Abstract：
:The effects of immunodepression on several disease states have constituted an important area of research, leading to the identification of relevant associations between immunodepression and a vast set of comorbidities, including infectious diseases, cardiovascular diseases and cancer. Research on the effects of immunodepression has mostly been conducted in individuals under immunodepression by the human immunodeficiency virus and transplant recipients under pharmacological immunosuppression, due to the difficulties in obtaining relevant samples sizes in other contexts of immunodepression. Overall, immunosuppressed individuals tend to show increased incidence of malignancies, but only transplant recipients show significantly increased incidence of skin cancer; human immunodeficiency virus-infected individuals only show increased incidence of malignancies of infectious origin. This paper presents a literature review on the effects of immunodepression in the development of tumours in humans, with special emphasis on the development of the different types of skin cancer. :Os efeitos da imunodepressão no desenvolvimento de estados de doença têm constituído uma importante área de investigação, tendo sido verificadas associações entre a imunodepressão e o desenvolvimento de um vasto conjunto de comorbilidades, entre as quais se destacam as doenças infeciosas, doenças cardiovasculares e o cancro. A investigação dos efeitos da imunodepressão em humanos tem sido sobretudo realizada em indivíduos imunodeprimidos pelo vírus da imunodeficiência humana e indivíduos sob imunossupressão farmacológica após transplante, devido aos constrangimentos associados à obtenção de amostras de número relevante noutros contextos. De um modo geral, doentes imunodeprimidos tendem a apresentar maior incidência de neoplasias malignas. No que respeita aos doentes transplantados, o cancro cutâneo tem uma incidência significativamente aumentada, ao passo que, entre doentes portadores da infeção com vírus da imunodeficiência humana, apenas as neoplasias de origem infeciosa apresentam incidência aumentada. Este artigo apresenta uma revisão da literatura relativa aos efeitos da imunodepressão no desenvolvimento de tumores em humanos, com especial enfâse no desenvolvimento dos diferentes tipos de cancro cutâneo.
journal_name
Acta Med Portjournal_title
Acta medica portuguesaauthors
Sanches MM,Travassos AR,Soares-de-Almeida Ldoi
10.20344/amp.7997subject
Has Abstractpub_date
2017-01-31 00:00:00pages
69-72issue
1eissn
0870-399Xissn
1646-0758journal_volume
30pub_type
杂志文章,评审abstract：:After defining U.I. as a symptom, sign and condition, the author claims, through epidemiological studies, that this reflects a major medical, social and economic problem. On the other hand the physiopathology of U.I. can be explained in a context of balance between the retention and emptying forces during the filling ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:Temporal arteritis is a chronic vasculitis of medium and large-size vessels and involves particularly extracranial branches of the aortic arch arteries. Authors report the case of a 73-year-old woman who presented to the hospital after looking for medical counselling three times because of unexplained fever, fatigue, ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2011-03-01 00:00:00
abstract：:On page 761, in the first sentence of the Introduction, where it reads: "Cardiovascular Botulinum toxin A (BoNT-A) has beenapproved for spasticity management."It should read: "Botulinum toxin A (BoNT-A) has been approved for spasticity management."Article published with errors: https://www.actamedicaportuguesa.com/rev...
journal_title：Acta medica portuguesa
pub_type： 已发布勘误
doi：10.20344/amp.15226
更新日期：2020-12-02 00:00:00
abstract：:The Authors retrospectively studied 17 patients who have been admitted to the Infectious Diseases Clinic of Coimbra University Hospital during a four year period and whose final diagnosis was brucellar spondylitis. Clinical, epidemiological, laboratory and imaging features are analyzed, as well as those related to the...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：:The authors present their clinical experience of leg and foot reconstruction with 227 clinical cases. Based on these cases the authors analyse the use of 18 musculocutaneous, 53 axial, 72 septocutaneous and 84 free flaps, totalling 29 different kinds of flaps performed. Although no definitive conclusions can be drawn ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1998-02-01 00:00:00
abstract：INTRODUCTION:Progressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by John Cunningham virus, mostly associated with immunodeficiency conditions, such as the human immunodeficiency virus infection. Progressive multifocal leukoencephalopathy can have multiple clinical ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：10.20344/amp.5950
更新日期：2015-05-01 00:00:00
abstract：:Elastosis perfurans serpiginosa is a rare perforating dermatosis found primarily in adolescents and young adults, characterized by transepidermal elimination of abnormal elastic fibers. The only drug known capable of inducing elastosis perfurans serpiginosa is D-penicillamine. We report the case of a 52 year-old woman...
journal_title：Acta medica portuguesa
pub_type：
doi：10.20344/amp.6749
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:The large wounds of the body wall, due to traumas, removal of tumors or prolonged laparostomies are a difficult surgical challenge with complex treatment. This paper presents the efficacy of the closure of large surgical wounds using rubber elastic bands. METHODS:One or two circular rubber elastic bands wer...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2011-05-01 00:00:00
abstract：INTRODUCTION:The surgical management of complete ureteral duplication anomalies is not consensual. OBJECTIVE:To characterize the pediatric population who underwent surgery for complete ureteral duplication and assess the outcomes of different approaches. MATERIAL AND METHODS:Clinical records from patients treated bet...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.6329
更新日期：2016-04-01 00:00:00
abstract：INTRODUCTION:The disruption of esophageal motility that characterizes achalasia typically provokes dysphagia, pain, loss of weight and malnutrition. Therefore, patients frequently report a reduction in quality of life and negative emotional states. Laparoscopic Heller myotomy proved to be an effective therapy, enabling...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.6758
更新日期：2016-02-01 00:00:00
abstract：:The aim of the study was to assess, in patients with non insulin dependent diabetes mellitus (NIDDM), either with previous failure to sulphonylureas or insulin treated since the disease started, if the combination of gliclazide to insulin therapy might induce a reduction of daily insulin requirement. 30 caucasian type...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1991-03-01 00:00:00
abstract：INTRODUCTION:An early investigation and management op cryptorchidism are essential for the diagnosis of associated pathologies, because intra-abdominal testis are associated with infertility and neoplasic risk. The authors describe a case of late presentation of cryptorchidism associated with genetic disorder. CASE RE...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
abstract：:Lithopedions are extremely rare conditions. Less than 300 cases were described worldwide. We report a case occurring in a woman of 77 years of age, admitted with dehydration, urinary tract infection and infected limb pressure ulcers. She had been recently admitted in a Surgery ward for incarcerated umbilical hernia. A...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2011-07-01 00:00:00
abstract：:The development of a kidney abscess is extremely rare despite the fact that urinary tract infections are quite common during pregnancy. The pathogenesis of renal abscess has changed over the years. Nowadays, more than 75% of the renal abscess arises from a previous urinary tract infection. The authors report the case ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2006-09-01 00:00:00
abstract：BACKGROUND:Meningitis is an uncommon clinical manifestation of invasive infection by Streptococcus pyogenes. CASE REPORT:A four years-old female child, previously healthy, started a history of high fever, associated to right otorrhea, prostration and vomiting. On admission she was haemodynamically stable but prostrate...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
abstract：:During pregnancy immunological, metabolic, hormonal and vascular changes occur, and can cause specific skin diseases. The specific dermatoses of pregnancy have undergone numerous changes in nomenclature and classification, partly due to advances in the knowledge of the pathogenesis of these skin diseases. Currently th...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：2013-09-01 00:00:00
abstract：:In Portugal, piroxicam is one of the most prescribed non-steroidal anti-inflammatory agents (NSAIDs) and is frequently associated to photosensitivity skin reactions, well known by all dermatologists. The authors review the physiopathology and clinical patterns of this adverse drug reaction. Importance is given to the ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：1998-11-01 00:00:00
abstract：:Inherited errors of purine and pyrimidine metabolism are a group of disorders with a broad spectrum of clinical manifestations. They may involve nervous, renal, haematological and immunological systems, presenting at any age. The incidence and prevalence of these disorders are unknown. Most clinicians are not aware of...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：BACKGROUND:Venous thromboembolism (VTE) risk assessment is a cornerstone for the achievement of best practices and outcomes. Epidemiologic data and practices related to venous thromboprophylaxis as considered by the global ENDORSE study, (Epidemiologic International Day for the Evaluation of Patients at Risk for Venous...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2011-11-01 00:00:00
abstract：OBJECTIVE:To compare the haemodynamic measurements of cardiac output (CO), central venous pressure (CVP), pulmonary capillary wedge pressure (Pw) and pulmonary artery systolic pressure (PASP), obtained by Swan-Ganz catheter and transthoracic echocardiography. MATERIAL AND METHODS:Prospective study in a Medical/Surgica...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
abstract：INTRODUCTION:Progressive multifocal leucoencefalopathy (PML) is a subacute demielinating disease of the Central Nervous System caused by the neurotropic virus John Cunningham (JC), common in immunodeficient patients, namely in HIV infection. PML encephalic lesions have a progressive nature that needs characterization a...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：2012-01-01 00:00:00
abstract：:Mitochondrial Encephalomyopathies are primary disorders of energy metabolism recently described. They are the result of mitochondrial abnormalities with a wide spectrum of syndromes implying a multisystemic but predominantly muscular and cerebral involvement. Biochemical, histological, imagiologic and clinical feature...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：1994-06-01 00:00:00
abstract：:The authors present a case of a 60-year-old male patient, previously diagnosed with B-cell chronic lymphocytic leukemia, who was admitted to the Emergency Room with dyspnea. The initial evaluation revealed severe anemia (Hgb = 5.0 g/dL) with hyperleukocytosis (800.000/µL), nearly all of the cells being mature lymphocy...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2016-05-01 00:00:00
abstract：:Fabry disease (FD) is a rare disorder resulting from mutations of the alpha-Galactosidase A lysosomal enzyme gene. Accumulation of enzyme substrates leads to multisystemic clinical manifestations and multiorgan progressive damage with high morbidity and mortality. Recombinant enzyme replacement therapy (RERT) now avai...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2010-05-01 00:00:00
abstract：:Sympathetic and parasympathetic nervous system evaluation was performed in 21 patients with rheumatoid arthritis. Every patient had autonomic nervous system (ANS) dysfunction, the parasympathetic involvement being the most frequent. ANS dysfunction may explain some manifestations and may well be the expression of a la...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：:Diaphragmatic Pacing was used to treat ventilatory failure in a young boy with bilateral diaphragmatic palsy secondary to cervical cord injury, on chronic mechanical ventilation for 6 months. The indications for diaphragmatic pacing in ventilatory failure were discussed, as well as the assessment of phrenic nerve inte...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：1995-11-01 00:00:00
abstract：INTRODUCTION:To evaluate sleep deprivation and its effects on young physicians in relation to concentration capacity and psychomotor performance. MATERIAL AND METHODS:Eighteen physicians aged 26 - 33 years were divided into 2 groups: non-sleep deprived group (with no night work) and sleep deprived group (minimum 12 ho...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.5777
更新日期：2015-07-01 00:00:00
abstract：INTRODUCTION:The immediate identification of infectious tuberculosis and implementation of effective isolation measures, are a priority of the national policies for disease control. OBJECTIVES:To identify clinical predictor's factors related with sputum smear-positive, in patients with pulmonary tuberculosis diagnosis...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2010-07-01 00:00:00
abstract：:The female varicocile is associated to the pelvic congestion syndrome that is described. Five patients 31 to 52 years old are presented. Four of them have continuous pelvic pain and the fifth had huge vaginal and vulvar varices. Flebography of the left ovarian vein showed retrograde flux of the dilated vein. Sclerothe...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：INTRODUCTION:Telemedicine is the provision of health services, where distance is a critical factor, using information and communication technologies. Cape Verde has bet on using this tool to increase access of the population of its islands to specialized care. MATERIAL AND METHODS:Qualitative study, covering the perio...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.7578
更新日期：2017-04-28 00:00:00
