Elemene for the treatment of lung cancer.

abstract：BACKGROUND:Rarer dementias include Huntington's disease (HD), cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), frontotemporal dementia (FTD), dementia in multiple sclerosis (MS) and progressive supranuclear palsy (PSP). Cholinesterase inhibitors, including donepezil,...

journal_title：The Cochrane database of systematic reviews

authors： Li Y,Hai S,Zhou Y,Dong BR

更新日期：2015-03-03 00:00:00

abstract：BACKGROUND:Primary open angle glaucoma (POAG) is a progressive optic neuropathy with an elevated intraocular pressure (IOP), where the optic nerve head becomes pathologically excavated and the visual field (VF) is characteristically altered. Ocular hypertension (OHT) is a condition with elevated IOP but without discern...

journal_title：The Cochrane database of systematic reviews

authors： Vass C,Hirn C,Sycha T,Findl O,Bauer P,Schmetterer L

更新日期：2007-10-17 00:00:00

abstract：BACKGROUND:Cycling is an attractive form of transport. It is beneficial to the individual as a form of physical activity that may fit more readily into an individual's daily routine, such as for cycling to work and to the shops, than other physical activities such as visiting a gym. Cycling is also beneficial to the wi...

journal_title：The Cochrane database of systematic reviews

authors： Mulvaney CA,Smith S,Watson MC,Parkin J,Coupland C,Miller P,Kendrick D,McClintock H

更新日期：2015-12-10 00:00:00

abstract：BACKGROUND:This is an updated version of the original review that was first published in the Cochrane Database of Systematic Reviews 2008, Issue 4. Laparoscopy has become an increasingly common approach to surgical staging of apparent early-stage ovarian tumours. This review was undertaken to assess the available evide...

journal_title：The Cochrane database of systematic reviews

authors： Lawrie TA,Medeiros LR,Rosa DD,da Rosa MI,Edelweiss MI,Stein AT,Zelmanowicz A,Ethur AB,Zanini RR

更新日期：2013-02-28 00:00:00

abstract：BACKGROUND:Intracerebral haemorrhage (ICH) causes significant morbidity and mortality. Prognosis for ICH patients is poor. Edaravone may be safe and effective in reducing the risk of early death and improving long-term functional outcomes in survivors. OBJECTIVES:To assess the safety and efficacy of edaravone for acut...

journal_title：The Cochrane database of systematic reviews

authors： Yang J,Liu M,Zhou J,Zhang S,Lin S,Zhao H

更新日期：2011-02-16 00:00:00

abstract：BACKGROUND:Gout is one of the most frequently occurring rheumatic diseases, worldwide. Given the well-known drawbacks of the regular treatments for acute gout (non-steroidal anti-inflammatory drugs (NSAIDs), colchicine), systemic corticosteroids might be safe alternatives. OBJECTIVES:To assess the efficacy and safety ...

journal_title：The Cochrane database of systematic reviews

authors： Janssens HJ,Lucassen PL,Van de Laar FA,Janssen M,Van de Lisdonk EH

更新日期：2008-04-16 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI), which is common in hospitalised patients, is associated with significant morbidity and mortality. Despite recent advances in treatment, AKI outcomes have not changed substantially during the past four decades, and incidence is increasing. There is an urgent need to explore novel th...

journal_title：The Cochrane database of systematic reviews

authors： Nigwekar SU,Strippoli GF,Navaneethan SD

更新日期：2013-01-31 00:00:00

abstract：BACKGROUND:Delivery of pain-free dentistry is crucial for reducing fear and anxiety, completion of treatment, and increasing acceptance of future dental treatment in children. Local anaesthetic (LA) facilitates this pain-free approach but it remains challenging. A number of interventions to help children cope with deli...

journal_title：The Cochrane database of systematic reviews

authors： Monteiro J,Tanday A,Ashley PF,Parekh S,Alamri H

更新日期：2020-02-27 00:00:00

abstract：BACKGROUND:Despite evidence supporting the effectiveness of diabetic retinopathy screening (DRS) in reducing the risk of sight loss, attendance for screening is consistently below recommended levels. OBJECTIVES:The primary objective of the review was to assess the effectiveness of quality improvement (QI) intervention...

journal_title：The Cochrane database of systematic reviews

authors： Lawrenson JG,Graham-Rowe E,Lorencatto F,Burr J,Bunce C,Francis JJ,Aluko P,Rice S,Vale L,Peto T,Presseau J,Ivers N,Grimshaw JM

更新日期：2018-01-15 00:00:00

abstract：BACKGROUND:Obstructive sleep apnoea is the periodic reduction (hypopnoea) or cessation (apnoea) of breathing due to narrowing or occlusion of the upper airway during sleep. The main symptom is daytime sleepiness and it has been suggested it is linked to premature death, hypertension, ischaemic heart disease, stroke and...

journal_title：The Cochrane database of systematic reviews

authors： Giles TL,Lasserson TJ,Smith BH,White J,Wright J,Cates CJ

更新日期：2006-07-19 00:00:00

abstract：BACKGROUND:Chronic wounds are common and present a health problem with significant effect on quality of life. Various pathologies may cause tissue breakdown, including poor blood supply resulting in inadequate oxygenation of the wound bed. Hyperbaric oxygen therapy (HBOT) has been suggested to improve oxygen supply to ...

journal_title：The Cochrane database of systematic reviews

authors： Kranke P,Bennett MH,Martyn-St James M,Schnabel A,Debus SE,Weibel S

更新日期：2015-06-24 00:00:00

abstract：BACKGROUND:Lactoferrin, a normal component of human colostrum and milk, can enhance host defenses and may be effective for prevention of sepsis and necrotizing enterocolitis (NEC) in preterm neonates. OBJECTIVES:Primary objective 1. To assess the safety and effectiveness of lactoferrin supplementation to enteral feeds...

journal_title：The Cochrane database of systematic reviews

authors： Pammi M,Suresh G

更新日期：2017-06-28 00:00:00

abstract：BACKGROUND:Decreased concentration of nitric oxide has been proposed as one of the possible cellular mechanisms of necrotising enterocolitis (NEC). Arginine can act as a substrate for production of nitric oxide in the tissues, and arginine supplementation may help to prevent NEC. OBJECTIVES:To examine the effect of ar...

journal_title：The Cochrane database of systematic reviews

authors： Shah PS,Shah VS,Kelly LE

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:Governments use different approaches to ensure that private for-profit healthcare services meet certain quality standards. Such government guidance, referred to as public stewardship, encompasses government policies, regulatory mechanisms, and implementation strategies for ensuring accountability in the deli...

journal_title：The Cochrane database of systematic reviews

authors： Wiysonge CS,Abdullahi LH,Ndze VN,Hussey GD

更新日期：2016-08-11 00:00:00

abstract：BACKGROUND:Epilepsy is a common chronic neurological disease with an estimated prevalence of 1% in the UK. Approximately one third of these people continue to have seizures despite drug treatment. In order to try to improve outcomes a number of new antiepileptic drugs have been developed and pregabalin is one of these....

journal_title：The Cochrane database of systematic reviews

authors： Pulman J,Hemming K,Marson AG

更新日期：2014-03-12 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA) is a systemic auto-immune disorder, involving persistent joint inflammation. NSAIDs are used to control the symptoms of RA, but are associated with significant gastro-intestinal toxicity, including a risk of potentially life threatening gastroduodenal perforations, ulcers and bleeds...

journal_title：The Cochrane database of systematic reviews

authors： Garner S,Fidan D,Frankish R,Judd M,Shea B,Towheed T,Wells G,Tugwell P

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Lifestyle changes and cardiovascular prevention measures are a primary treatment for intermittent claudication (IC). Symptomatic treatment with vasoactive agents (Anatomic Therapeutic Chemical Classification (ATC) for medicines from the World Health Organisation class CO4A) is controversial. OBJECTIVES:To e...

journal_title：The Cochrane database of systematic reviews

authors： de Backer TL,Vander Stichele R,Lehert P,Van Bortel L

更新日期：2012-12-12 00:00:00

abstract：BACKGROUND:In most pregnancies that miscarry, arrest of embryonic or fetal development occurs some time (often weeks) before the miscarriage occurs. Ultrasound examination can reveal abnormal findings during this phase by demonstrating anembryonic pregnancies or embryonic or fetal death. Treatment has traditionally bee...

journal_title：The Cochrane database of systematic reviews

authors： Lemmers M,Verschoor MA,Kim BV,Hickey M,Vazquez JC,Mol BWJ,Neilson JP

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:Interstitial lung disease (ILD) is characterised by reduced functional capacity, dyspnoea and exercise-induced hypoxia. Pulmonary rehabilitation, an intervention that includes exercise training, is beneficial for people with other chronic lung conditions; however its effects in ILD have not been well charact...

journal_title：The Cochrane database of systematic reviews

authors： Dowman L,Hill CJ,Holland AE

更新日期：2014-10-06 00:00:00

abstract：BACKGROUND:Liver transplantation is an established treatment option for end-stage liver failure. Now that newer, more potent immunosuppressants have been developed, glucocorticosteroids may no longer be needed and their removal may prevent adverse effects. OBJECTIVES:To assess the benefits and harms of glucocorticoste...

journal_title：The Cochrane database of systematic reviews

authors： Fairfield C,Penninga L,Powell J,Harrison EM,Wigmore SJ

更新日期：2018-04-09 00:00:00

abstract：BACKGROUND:Despite use in many countries of tapered methadone for detoxification from opiate, the evidence of efficacy to prevent relapse and promote lifestyle change has not been systematically evaluated. OBJECTIVES:To determine whether tapered methadone is effective to manage withdrawal from opioids. SEARCH STRATEG...

journal_title：The Cochrane database of systematic reviews

authors： Amato L,Davoli M,Ferri M,Ali R

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Myofascial pain syndrome (MPS) is a regional muscular pain syndrome characterised by the presence of trigger points, which are painful points in one or more muscles. The pain can be felt at the site where the trigger point is located or it can be felt away from that place when the muscle is pressed (referred...

journal_title：The Cochrane database of systematic reviews

authors： Soares A,Andriolo RB,Atallah AN,da Silva EM

更新日期：2012-04-18 00:00:00

abstract：BACKGROUND:Intermittent pneumatic compression (IPC) is a mechanical method of delivering compression to swollen limbs that can be used to treat venous leg ulcers and limb swelling due to lymphoedema. OBJECTIVES:To determine whether IPC increases the healing of venous leg ulcers. To determine the effects of IPC on heal...

journal_title：The Cochrane database of systematic reviews

authors： Nelson EA,Hillman A,Thomas K

更新日期：2014-05-12 00:00:00

abstract：BACKGROUND:Cholecystectomy is a common surgical procedure. In the open cholecystectomy area, antibiotic prophylaxis showed beneficial effects, but it is not known if its benefits and harms are similar in laparoscopic cholecystectomy. Some clinical trials suggest that antibiotic prophylaxis may not be necessary in lapar...

journal_title：The Cochrane database of systematic reviews

authors： Sanabria A,Dominguez LC,Valdivieso E,Gomez G

更新日期：2010-12-08 00:00:00

abstract：BACKGROUND:Graduated driver licensing (GDL) has been proposed as a means of reducing crash rates among novice drivers by gradually introducing them to higher risk driving situations. OBJECTIVES:To examine the effectiveness of GDL systems in reducing crash rates of young drivers. SEARCH STRATEGY:Studies were identifie...

journal_title：The Cochrane database of systematic reviews

authors： Hartling L,Wiebe N,Russell K,Petruk J,Spinola C,Klassen TP

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:So-called 'third wave' cognitive and behavioural therapies represent a new generation of psychological therapies that are increasingly being used in the treatment of psychological problems. However, the effectiveness and acceptability of third-wave cognitive and behavioural therapy (CBT) approaches as treatm...

journal_title：The Cochrane database of systematic reviews

authors： Churchill R,Moore TH,Furukawa TA,Caldwell DM,Davies P,Jones H,Shinohara K,Imai H,Lewis G,Hunot V

更新日期：2013-10-18 00:00:00

abstract：BACKGROUND:In osteogenesis imperfecta (OI) a genetic defect in type I collagen results in multiple fractures with little or no trauma. Bisphosphonates are used to attempt to reduce these fractures. OBJECTIVES:To assess the effectiveness and safety of bisphosphonates in increasing bone mineral density (BMD), reducing f...

journal_title：The Cochrane database of systematic reviews

authors： Phillipi CA,Remmington T,Steiner RD

更新日期：2008-10-08 00:00:00

abstract：BACKGROUND:Asthma is a common condition characterised by airway inflammation and airway narrowing, which can result in intermittent symptoms of wheezing, coughing and chest tightness, possibly limiting activities of daily life. Water-based exercise is believed to offer benefits for people with asthma through pollen-fre...

journal_title：The Cochrane database of systematic reviews

authors： Grande AJ,Silva V,Andriolo BN,Riera R,Parra SA,Peccin MS

更新日期：2014-07-17 00:00:00

abstract：BACKGROUND:Asthma management guidelines recommend low-dose inhaled corticosteroids (ICS) as first-line therapy for adults and adolescents with persistent asthma. The addition of anti-leukotriene agents to ICS offers a therapeutic option in cases of suboptimal control with daily ICS. OBJECTIVES:To assess the efficacy a...

journal_title：The Cochrane database of systematic reviews

authors： Chauhan BF,Jeyaraman MM,Singh Mann A,Lys J,Abou-Setta AM,Zarychanski R,Ducharme FM

更新日期：2017-03-16 00:00:00

abstract：BACKGROUND:Poliomyelitis mainly affects unvaccinated children under five years of age, causing irreversible paralysis or even death. The oral polio vaccine (OPV) contains live attenuated virus, which can, in rare cases, cause a paralysis known as vaccine-associated paralytic polio (VAPP), and also vaccine-derived polio...

journal_title：The Cochrane database of systematic reviews

authors： Ciapponi A,Bardach A,Rey Ares L,Glujovsky D,Cafferata ML,Cesaroni S,Bhatti A

更新日期：2019-12-05 00:00:00