Impaired Firing Behavior of Individually Tracked Paretic Motor Units During Fatiguing Contractions of the Dorsiflexors and Functional Implications Post Stroke.

abstract：:Accurate prediction of the early stage of Alzheimer's disease (AD) is important but very challenging. The goal of this study was to utilize predictors for diagnosis conversion to AD based on integrating resting-state functional MRI (rs-fMRI) connectivity analysis and structural MRI (sMRI). We included 177 subjects in ...

journal_title：Frontiers in neurology

authors： Hojjati SH,Ebrahimzadeh A,Babajani-Feremi A

更新日期：2019-08-30 00:00:00

abstract：:Aims: To examine trajectories of employment probability up to 10 years following moderate-to-severe traumatic brain injury (TBI) and identify significant predictors from baseline socio-demographic and injury characteristics. Methods: A longitudinal observational study followed 97 individuals with moderate-to-severe TB...

journal_title：Frontiers in neurology

authors： Howe EI,Andelic N,Perrin PB,Røe C,Sigurdardottir S,Arango-Lasprilla JC,Lu J,Løvstad M,Forslund MV

更新日期：2018-12-05 00:00:00

abstract：PURPOSE:Traumatic brain injury involving loss of consciousness has focal effects in the human brainstem, suggesting that it may have particular consequences for eye movement control. This hypothesis was investigated by measurements of vergence eye movement parameters. METHODS:Disparity vergence eye movements were meas...

journal_title：Frontiers in neurology

authors： Tyler CW,Likova LT,Mineff KN,Elsaid AM,Nicholas SC

更新日期：2015-02-03 00:00:00

abstract：:Localization of the epileptogenic zone (EZ) is crucial in the surgical treatment of focal epilepsy. Recently, EEG studies have revealed that the EZ exhibits abnormal connectivity, which has led investigators to now consider connectivity as a biomarker to localize the EZ. Further, abnormal connectivity of the EZ may pr...

journal_title：Frontiers in neurology

authors： Gupta K,Grover P,Abel TJ

更新日期：2020-11-25 00:00:00

abstract：:Objective: As a recently defined disease entity, vestibular migraine (VM) is a variant of migraine with broad spectrum of manifestations. We evaluated a prospective cohort of patients with VM in two centers to assess severity of VM attacks and investigate its contributing factors in patients with VM. Methods: Adult pa...

journal_title：Frontiers in neurology

authors： Liu W,Dong H,Yang L,Zhao H,Dong W,Yang Y

更新日期：2020-12-16 00:00:00

abstract：:Microglia are activated during pathological events in the brain and are capable of releasing various types of inflammatory cytokines. Here, we demonstrate that the addition of 5% microglia activated by 1 μg/ml lipopolysaccharides (LPS) to hippocampal cultures upregulates Na(+) current densities (INavD) of bipolar as w...

journal_title：Frontiers in neurology

authors： Klapal L,Igelhorst BA,Dietzel-Meyer ID

更新日期：2016-03-30 00:00:00

abstract：:Introduction: Eslicarbazepine acetate (ESL) is an antiepileptic drug approved as monotherapy or add-on for the treatment of epilepsy with seizures of focal onset. ESL owns a good profile in terms of efficacy and tolerability, but its effects on EEG activity and connectivity are unknown. The purpose of this study was t...

journal_title：Frontiers in neurology

authors： Pellegrino G,Mecarelli O,Pulitano P,Tombini M,Ricci L,Lanzone J,Brienza M,Davassi C,Di Lazzaro V,Assenza G

更新日期：2018-12-11 00:00:00

abstract：:Autism Spectrum Disorders comprise conditions that may affect cognitive development, motor skills, social interaction, communication, and behavior. This set of functional deficits often results in lack of independence for the diagnosed individuals, and severe distress for patients, families, and caregivers. There is a...

journal_title：Frontiers in neurology

authors： Fleury-Teixeira P,Caixeta FV,Ramires da Silva LC,Brasil-Neto JP,Malcher-Lopes R

更新日期：2019-10-31 00:00:00

abstract：:This review begins with the history of the events starting with the death of Libby Zion that lead to the Bell Commission, that the studied her death and made recommendations for improvement that were codified into law in New York state as the 405 law that the ACGME essentially adopted in putting a cap on work hours an...

journal_title：Frontiers in neurology

authors： Kramer M

更新日期：2010-10-20 00:00:00

abstract：:Background: Differentiating idiopathic Parkinson's disease (IPD) from atypical Parkinsonian disorders (APD) is challenging, especially in early disease stages. Postural instability and gait difficulty (PIGD) are substantial motor impairments of IPD and APD. Clinical evidence implies that patients with APD have larger ...

journal_title：Frontiers in neurology

authors： Gaßner H,Raccagni C,Eskofier BM,Klucken J,Wenning GK

更新日期：2019-01-22 00:00:00

abstract：:Objective: The platelet-to-lymphocyte ratio (PLR) is a new marker of atherosclerotic inflammation and has been identified as a predictive factor in cardiovascular diseases, but its significance in patients with acute ischaemic stroke (AIS) who have undergone intravenous thrombolysis (IVT) is still unknown. Methods: Co...

journal_title：Frontiers in neurology

authors： Xu JH,He XW,Li Q,Liu JR,Zhuang MT,Huang FF,Bao GS

更新日期：2019-11-13 00:00:00

abstract：Background:Cerebral microcirculation after severe head injury is heterogeneous and temporally variable. Microcirculation is dependent upon the severity of injury, and it is unclear how histology relates to cerebral regional blood flow. Objective:This study assesses the changes of cerebral microcirculation blood flow o...

journal_title：Frontiers in neurology

authors： Bellapart J,Cuthbertson K,Dunster K,Diab S,Platts DG,Raffel OC,Gabrielian L,Barnett A,Paratz J,Boots R,Fraser JF

更新日期：2018-05-07 00:00:00

abstract：:PLA2G6 has been certified as a causative gene in patients with autosomal recessive early-onset Parkinson's disease (EOPD). We reported an EOPD case caused by PLA2G6 gene mutation, and performed neurological examination, genetic analysis, and multimodal neuroimaging to describe this phenotype. A compound heterozygous m...

journal_title：Frontiers in neurology

authors： Shen T,Hu J,Jiang Y,Zhao S,Lin C,Yin X,Yan Y,Pu J,Lai HY,Zhang B

更新日期：2019-08-21 00:00:00

abstract：Background:Previous studies demonstrated that cardioembolism (CE) was prone to develop hemorrhagic transformation (HT), whereas hyper-permeability of blood-brain barrier (BBB) might be one reason for the development of HT. We, thus, aimed to investigate whether the BBB permeability (BBBP) was higher in CE stroke than o...

journal_title：Frontiers in neurology

authors： Liu C,Shi F,Chen Z,Yan S,Ding X,Lou M

更新日期：2018-02-08 00:00:00

abstract：:Introduction: Symptoms following a mild traumatic brain injury (mTBI) usually resolve quickly but may persist past 3 months in up to 15% of children. Mechanisms of mTBI recovery are poorly understood, but may involve alterations in cortical neurophysiology. Transcranial Magnetic Stimulation (TMS) can non-invasively in...

journal_title：Frontiers in neurology

authors： King R,Kirton A,Zewdie E,Seeger TA,Ciechanski P,Barlow KM

更新日期：2019-05-17 00:00:00

abstract：:Recurrent stroke is becoming an increasingly important public health issue owing to the increased risk of disability and death. However, population-based studies investigating the rate of recurrent stroke in China are rare. We explored the rate and determinants of recurrent stroke within 1 and 5 years after the initia...

journal_title：Frontiers in neurology

authors： Han J,Mao W,Ni J,Wu Y,Liu J,Bai L,Shi M,Tu J,Ning X,Wang J

更新日期：2020-01-23 00:00:00

abstract：:Chronic subdural hematoma (cSDH) is a common disease process associated with significant morbidity that occurs most often in elderly patients. Asymptomatic patients are typically treated conservatively, with surgical intervention reserved for patients with symptomatic and/or large hematomas that cause brain compressio...

journal_title：Frontiers in neurology

authors： Catapano JS,Nguyen CL,Wakim AA,Albuquerque FC,Ducruet AF

更新日期：2020-10-20 00:00:00

abstract：:Background and Purpose: Stability stratification of intracranial aneurysms (IAs) is crucial for individualized clinical management, especially for small IAs. We aim to develop and validate a nomogram based on clinical and morphological risk factors for individualized instability stratification of small IAs. Methods: S...

journal_title：Frontiers in neurology

authors： Zhu W,Li W,Tian Z,Zhang M,Zhang Y,Wang K,Zhang Y,Yang X,Liu J

更新日期：2021-01-15 00:00:00

abstract：:Background: Automated ASPECTS has the potential of reducing interobserver variability in the determination of early ischemic changes. We aimed to assess the performance of an automated ASPECTS vs. ASPECTS interpreted for sent CT images on WhatsApp and to correlate these results with the outcome. Materials and Methods:...

journal_title：Frontiers in neurology

authors： Mansour OY,Ramadan I,Abdo A,Hamdi M,Eldeeb H,Marouf H,Elsalamawy D,Elfatatry A,Elnekidy A,Reda MI

更新日期：2020-05-19 00:00:00

abstract：:Background: Sphingosine 1-phosphate (S1P) is a lipid metabolite that mediates various physiological processes, including vascular endothelial cell function, inflammation, coagulation/thrombosis, and angiogenesis. As a result, S1P may contribute to the pathogenesis of stroke. Objective: This study aimed to evaluate the...

journal_title：Frontiers in neurology

authors： Liu J,Sugimoto K,Cao Y,Mori M,Guo L,Tan G

更新日期：2020-09-08 00:00:00

abstract：:Approaches to furthering our understanding of the bioeffects, behavioral changes, and treatment options following exposure to blast are a worldwide priority. Of particular need is a more concerted effort to employ animal models to determine possible sex differences, which have been reported in the clinical literature....

journal_title：Frontiers in neurology

authors： McCabe JT,Tucker LB

更新日期：2020-09-30 00:00:00

abstract：:Objective: Myotonia congenita (MC) is a rare muscle disease characterized by sarcolemma over-excitability inducing skeletal muscle stiffness. It can be inherited either as an autosomal dominant (Thomsen's disease) or an autosomal recessive (Becker's disease) trait. Both types are caused by loss-of-function mutations i...

journal_title：Frontiers in neurology

authors： Altamura C,Ivanova EA,Imbrici P,Conte E,Camerino GM,Dadali EL,Polyakov AV,Kurbatov SA,Girolamo F,Carratù MR,Desaphy JF

更新日期：2020-09-04 00:00:00

abstract：Objective:To investigate the correlation between initial response to antiepileptic drugs (AEDs) and long-term outcomes after 3 years in patients with newly diagnosed epilepsy. Methods:This prospective study included 204 patients with newly diagnosed epilepsy, who were followed-up for at least 36 months. The long-term ...

journal_title：Frontiers in neurology

authors： Xia L,Ou S,Pan S

更新日期：2017-12-08 00:00:00

abstract：:Objective: Health care personnel in Europe is increasingly involved in care of displaced persons from non-European countries; we investigated the spectrum of neurological disorders and medical management in refugees presenting to the emergency room (ER) of a German university hospital. Methods: We retrospectively stud...

journal_title：Frontiers in neurology

authors： Brinckmann MP,van Noort BM,Leithner C,Ploner CJ

更新日期：2018-12-11 00:00:00

abstract：:Objective: Episodic memory is frequently impaired in Multiple Sclerosis (MS), but the cognitive characteristics and neuropsychological processes involved remain controversial. Our aim was to study episodic memory dysfunction in MS, using the LASSI-L, a novel memory-based cognitive stress test that uses a new paradigm ...

journal_title：Frontiers in neurology

authors： Matias-Guiu JA,Cortés-Martínez A,Curiel RE,Delgado-Álvarez A,Fernández-Oliveira A,Pytel V,Montero P,Moreno-Ramos T,Loewenstein DA,Matías-Guiu J

更新日期：2020-04-21 00:00:00

abstract：:Although orthodontic treatment is common, orthodontic force often induced pain. Low-level laser therapy (LLLT) has been investigated to improve therapeutic comfort. In dentistry, LLLT is mainly applied using two types of lasers, CO2 and diode lasers, whose biological actions are thought to be associated with wavelengt...

journal_title：Frontiers in neurology

authors： Tsuchiya T,Hasegawa N,Yugawa M,Sasaki A,Suda N,Adachi K

更新日期：2020-06-05 00:00:00

abstract：:Patients with severe mental illnesses may present extrapyramidal symptoms as part of a concomitant neurological disorder or secondary to medications. Extrapyramidal symptoms are frequently unrecognized, have negative consequences for adherence to treatment, negatively affect quality of life and can induce stigma. We e...

journal_title：Frontiers in neurology

authors： Roiter B,Pigato G,Antonini A

更新日期：2020-11-10 00:00:00

abstract：:Apathy is pervasive across many neuropsychiatric disorders but is poorly characterized mechanistically, so targeted therapeutic interventions remain elusive. A key impediment has been the lack of validated assessment tools to facilitate translation of promising findings between preclinical disease models and patients....

journal_title：Frontiers in neurology

authors： Heath CJ,O'Callaghan C,Mason SL,Phillips BU,Saksida LM,Robbins TW,Barker RA,Bussey TJ,Sahakian BJ

更新日期：2019-08-09 00:00:00

abstract：:Glycogenosis VII (GSD VII) is a rare autosomal recessive glycogen storage disorder caused by mutations in the PFKM gene encoding the phosphofructokinase (PFK) enzyme. A classical form with exercise intolerance, contractures, and myoglobinuria, a severe multisystem infantile form, an hemolytic variant and a late-onset ...

journal_title：Frontiers in neurology

authors： Filosto M,Cotti Piccinelli S,Pichiecchio A,Musumeci O,Galvagni A,Caria F,Gallo Cassarino S,Baldelli E,Vitale R,Padovani A,Toscano A

更新日期：2019-02-07 00:00:00

abstract：INTRODUCTION:Limited evidence exists on effective interventions to improve knowledge of preventive medications in patients with chronic diseases, such as stroke. We investigated the effectiveness of a nurse-led intervention, where a component was to improve knowledge of prevention medications, in patients with stroke o...

journal_title：Frontiers in neurology

authors： Olaiya MT,Cadilhac DA,Kim J,Ung D,Nelson MR,Srikanth VK,Bladin CF,Gerraty RP,Fitzgerald SM,Phan TG,Frayne J,Thrift AG

更新日期：2016-11-18 00:00:00