Serum magnesium levels and risk of coronary artery disease: Mendelian randomisation study.

abstract：BACKGROUND:Although vaccination has been proved to be a safe, efficacious, and cost-effective intervention, immunisation rates remain suboptimal in many European countries, resulting in poor control of many vaccine-preventable diseases. DISCUSSION:The Summit of Independent European Vaccination Experts focused on the p...

journal_title：BMC medicine

authors： Schmitt HJ,Booy R,Aston R,Van Damme P,Schumacher RF,Campins M,Rodrigo C,Heikkinen T,Weil-Olivier C,Finn A,Olcén P,Fedson D,Peltola H

更新日期：2007-05-29 00:00:00

abstract：BACKGROUND:Armed conflict can indirectly affect population health through detrimental impacts on political and social institutions and destruction of infrastructure. This study aimed to quantify indirect mortality impacts of armed conflict in civilian populations globally and explore differential effects by armed confl...

journal_title：BMC medicine

authors： Jawad M,Hone T,Vamos EP,Roderick P,Sullivan R,Millett C

更新日期：2020-09-10 00:00:00

abstract：BACKGROUND:The peer review process is a cornerstone of biomedical research. We aimed to evaluate the impact of interventions to improve the quality of peer review for biomedical publications. METHODS:We performed a systematic review and meta-analysis. We searched CENTRAL, MEDLINE (PubMed), Embase, Cochrane Database of...

journal_title：BMC medicine

authors： Bruce R,Chauvin A,Trinquart L,Ravaud P,Boutron I

更新日期：2016-06-10 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer deaths globally. However, there is overwhelming evidence that a large proportion of CRC cases and deaths could be prevented by screening. Nevertheless, CRC screening programmes are offered in a minority of coun...

journal_title：BMC medicine

authors： Brenner H,Stock C,Hoffmeister M

更新日期：2015-10-13 00:00:00

abstract：BACKGROUND:Wide implementation of mammography screening has resulted in increased numbers of women diagnosed with breast carcinoma in situ. We aimed to determine the risk of invasive breast cancer in relatives of patients with breast carcinoma in situ in comparison to the risk in relatives of patients with invasive bre...

journal_title：BMC medicine

authors： Mukama T,Fallah M,Brenner H,Xu X,Sundquist K,Sundquist J,Kharazmi E

更新日期：2020-11-05 00:00:00

abstract：BACKGROUND:To reduce inequalities between individuals with and without mental health problems, a better understanding is required of triggers and success of quit attempts among the third of smokers with mental health problems. The aim was to assess whether there are differences by mental health status in (i) triggers f...

journal_title：BMC medicine

authors： Brose LS,Brown J,McNeill A

更新日期：2020-06-25 00:00:00

abstract：BACKGROUND:In animal models, lack of thyroid hormone is associated with cone photoreceptor preservation, while administration of high doses of active thyroid hormone leads to deterioration. The association between thyroid function and age-related macular degeneration (AMD) has not been investigated in the general popul...

journal_title：BMC medicine

authors： Chaker L,Buitendijk GH,Dehghan A,Medici M,Hofman A,Vingerling JR,Franco OH,Klaver CC,Peeters RP

更新日期：2015-04-23 00:00:00

abstract：BACKGROUND:While step counter use has become popular among type 2 diabetes (T2D) patients, its effectiveness in increasing physical activity (PA) and improving glycemic control has been poorly defined. The aim of this meta-analysis of randomized controlled trials (RCTs) was to evaluate the association of step counter u...

journal_title：BMC medicine

authors： Qiu S,Cai X,Chen X,Yang B,Sun Z

更新日期：2014-02-27 00:00:00

abstract：BACKGROUND:The benign character formerly attributed to Plasmodium vivax infection has been dismantled by the increasing number of reports of severe disease associated with infection with this parasite, prompting the need for more thorough and comprehensive characterization of the spectrum of resulting clinical complica...

journal_title：BMC medicine

authors： Siqueira AM,Lacerda MV,Magalhães BM,Mourão MP,Melo GC,Alexandre MA,Alecrim MG,Kochar D,Kochar S,Kochar A,Nayak K,del Portillo H,Guinovart C,Alonso P,Bassat Q

更新日期：2015-03-20 00:00:00

abstract：BACKGROUND:Accurate and timely cause of death (COD) data are essential for informed public health policymaking. Medical certification of COD generally provides the majority of COD data in a population and is an essential component of civil registration and vital statistics (CRVS) systems. Accurate completion of the med...

journal_title：BMC medicine

authors： Hart JD,Sorchik R,Bo KS,Chowdhury HR,Gamage S,Joshi R,Kwa V,Li H,Mahesh BPK,Mclaughlin D,Mikkelsen L,Miki J,Napulan R,Rampatige R,Reeve M,Sarmiento C,War NS,Richards N,Riley ID,Lopez AD

更新日期：2020-03-09 00:00:00

abstract：BACKGROUND:Current policies encourage healthcare institutions to acquire clinical information systems (CIS) so that captured data can be used for secondary purposes, including clinical process improvement. Such policies do not account for the extra work required to repurpose data for uses other than direct clinical car...

journal_title：BMC medicine

authors： Morrison C,Jones M,Jones R,Vuylsteke A

更新日期：2013-04-10 00:00:00

abstract：BACKGROUND:In recent years, medical practice has followed two different paradigms: evidence-based medicine (EBM) and values-based medicine (VBM). There is an urgent need to promote medical education that strengthens the relationship between these two paradigms. This work is designed to establish the foundations for a c...

journal_title：BMC medicine

authors： Altamirano-Bustamante MM,Altamirano-Bustamante NF,Lifshitz A,Mora-Magaña I,de Hoyos A,Avila-Osorio MT,Quintana-Vargas S,Aguirre JA,Méndez J,Murata C,Nava-Diosdado R,Martínez-González O,Calleja E,Vargas R,Mejía-Arangure JM,C

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:Cardiovascular Risk Factors, Aging, and Incidence of Dementia (CAIDE) risk score is the only currently available midlife risk score for dementia. We compared CAIDE to Framingham cardiovascular Risk Score (FRS) and FINDRISC diabetes score as predictors of dementia and assessed the role of age in their associa...

journal_title：BMC medicine

authors： Fayosse A,Nguyen DP,Dugravot A,Dumurgier J,Tabak AG,Kivimäki M,Sabia S,Singh-Manoux A

更新日期：2020-05-19 00:00:00

abstract：BACKGROUND:Mathematical and computational models for infectious diseases are increasingly used to support public-health decisions; however, their reliability is currently under debate. Real-time forecasts of epidemic spread using data-driven models have been hindered by the technical challenges posed by parameter estim...

journal_title：BMC medicine

authors： Tizzoni M,Bajardi P,Poletto C,Ramasco JJ,Balcan D,Gonçalves B,Perra N,Colizza V,Vespignani A

更新日期：2012-12-13 00:00:00

abstract：:Nanooncology, the application of nanobiotechnology to the management of cancer, is currently the most important chapter of nanomedicine. Nanobiotechnology has refined and extended the limits of molecular diagnosis of cancer, for example, through the use of gold nanoparticles and quantum dots. Nanobiotechnology has als...

journal_title：BMC medicine

authors： Jain KK

更新日期：2010-12-13 00:00:00

abstract：BACKGROUND:In an era when obesity prevalence is high throughout much of the world, there is a correspondingly pervasive and strong culture of weight stigma. For example, representative studies show that some forms of weight discrimination are more prevalent even than discrimination based on race or ethnicity. DISCUSSI...

journal_title：BMC medicine

authors： Tomiyama AJ,Carr D,Granberg EM,Major B,Robinson E,Sutin AR,Brewis A

更新日期：2018-08-15 00:00:00

abstract：BACKGROUND:Dietary assessment is complex, and strategies to select the most appropriate dietary assessment tool (DAT) in epidemiological research are needed. The DIETary Assessment Tool NETwork (DIET@NET) aimed to establish expert consensus on Best Practice Guidelines (BPGs) for dietary assessment using self-report. M...

journal_title：BMC medicine

authors： Cade JE,Warthon-Medina M,Albar S,Alwan NA,Ness A,Roe M,Wark PA,Greathead K,Burley VJ,Finglas P,Johnson L,Page P,Roberts K,Steer T,Hooson J,Greenwood DC,Robinson S,DIET@NET consortium.

更新日期：2017-11-15 00:00:00

abstract：:Primary care clinicians and researchers are growing increasingly aware of the prevalence of multimorbidity among long-term conditions, and the impact on patient experience, health, and utilisation of care. The correspondence paper by Muth et al. entitled 'The Ariadne principles: how to handle multimorbidity in primary...

journal_title：BMC medicine

authors： Bower P

更新日期：2014-12-08 00:00:00

abstract：BACKGROUND:Although a number of risk factors are known to predict mortality within the first years after myocardial infarction, little is known about interactions between risk factors, whereas these could contribute to accurate differentiation of patients with higher and lower risk for mortality. This study explored th...

journal_title：BMC medicine

authors： van Loo HM,van den Heuvel ER,Schoevers RA,Anselmino M,Carney RM,Denollet J,Doyle F,Freedland KE,Grace SL,Hosseini SH,Parakh K,Pilote L,Rafanelli C,Roest AM,Sato H,Steeds RP,Kessler RC,de Jonge P

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:Over the last 100 years, several persistent misconceptions or 'false beliefs' have built up around allergen immunotherapy and its use in allergic rhinitis. This is perhaps because enthusiastic physicians administered complex allergen extracts to a diverse population of patients suffering from heterogeneous a...

journal_title：BMC medicine

authors： Calderón MA,Frankland AW,Demoly P

更新日期：2013-12-05 00:00:00

abstract：BACKGROUND:Human T lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic myelopathy characterized by motor dysfunction of the lower extremities and urinary disturbance. Immunomodulatory treatments are the main strategy for HAM/TSP, but several issues are associated...

journal_title：BMC medicine

authors： Nakamura T,Matsuo T,Fukuda T,Yamato S,Yamaguchi K,Kinoshita I,Matsuzaki T,Nishiura Y,Nagasato K,Narita-Masuda T,Nakamura H,Satoh K,Sasaki H,Sakai H,Kawakami A

更新日期：2013-08-15 00:00:00

abstract：BACKGROUND:Tumor necrosis factor (TNF)-α inhibitors are increasingly being used in inflammatory bowel disease (IBD). Because this chronic intestinal disorder often affects women of fertile age, it is essential to assess the effect of biologics on pregnancy outcome. METHODS:We performed a systematic review of the Engli...

journal_title：BMC medicine

authors： Nielsen OH,Loftus EV Jr,Jess T

更新日期：2013-07-31 00:00:00

abstract：BACKGROUND:A sizeable fraction of tuberculosis (TB) cases go undiagnosed. By analysing data from enhanced demographic, microbiological and geospatial surveillance of TB registrations, we aimed to identify modifiable predictors of inequitable access to diagnosis and care. METHODS:Governmental community health workers (...

journal_title：BMC medicine

authors： MacPherson P,Khundi M,Nliwasa M,Choko AT,Phiri VK,Webb EL,Dodd PJ,Cohen T,Harris R,Corbett EL

更新日期：2019-01-29 00:00:00

abstract：BACKGROUND:In adults with febrile urinary tract infection (fUTI), data on optimal treatment duration in patients other than non-pregnant women without comorbidities are lacking. METHODS:A randomized placebo-controlled, double-blind, non-inferiority trial among 35 primary care centers and 7 emergency departments of reg...

journal_title：BMC medicine

authors： van Nieuwkoop C,van der Starre WE,Stalenhoef JE,van Aartrijk AM,van der Reijden TJ,Vollaard AM,Delfos NM,van 't Wout JW,Blom JW,Spelt IC,Leyten EM,Koster T,Ablij HC,van der Beek MT,Knol MJ,van Dissel JT

更新日期：2017-04-03 00:00:00

abstract：BACKGROUND:Contrast-induced nephropathy is an important cause of acute renal failure. We assess the efficacy of acetylcysteine for prevention of contrast-induced nephropathy among patients undergoing intravascular angiography. METHODS:We conducted a systematic review and meta-analysis of randomized controlled trials c...

journal_title：BMC medicine

authors： Bagshaw SM,Ghali WA

更新日期：2004-10-22 00:00:00

abstract：BACKGROUND:Polymorphism in antigens is a common mechanism for immune evasion used by many important pathogens, and presents major challenges in vaccine development. In malaria, many key immune targets and vaccine candidates show substantial polymorphism. However, knowledge on antigenic diversity of key antigens, the im...

journal_title：BMC medicine

authors： Terheggen U,Drew DR,Hodder AN,Cross NJ,Mugyenyi CK,Barry AE,Anders RF,Dutta S,Osier FH,Elliott SR,Senn N,Stanisic DI,Marsh K,Siba PM,Mueller I,Richards JS,Beeson JG

更新日期：2014-10-16 00:00:00

abstract：BACKGROUND:Ancestral environmental exposures to a variety of environmental factors and toxicants have been shown to promote the epigenetic transgenerational inheritance of adult onset disease. The present work examined the potential transgenerational actions of the insecticide dichlorodiphenyltrichloroethane (DDT) on o...

journal_title：BMC medicine

authors： Skinner MK,Manikkam M,Tracey R,Guerrero-Bosagna C,Haque M,Nilsson EE

更新日期：2013-10-23 00:00:00

abstract：BACKGROUND:We now know that depression is associated with a chronic, low-grade inflammatory response and activation of cell-mediated immunity, as well as activation of the compensatory anti-inflammatory reflex system. It is similarly accompanied by increased oxidative and nitrosative stress (O&NS), which contribute to ...

journal_title：BMC medicine

authors： Berk M,Williams LJ,Jacka FN,O'Neil A,Pasco JA,Moylan S,Allen NB,Stuart AL,Hayley AC,Byrne ML,Maes M

更新日期：2013-09-12 00:00:00

abstract：BACKGROUND:Many agree that the biopsychosocial contributions to psychopathology are complex, yet it is unclear how we can make sense of this complexity. One approach is to reduce this complexity to a few necessary and sufficient biopsychosocial factors; although this approach is easy to understand, it has little explan...

journal_title：BMC medicine

authors： Franklin JC

更新日期：2019-10-18 00:00:00

abstract：BACKGROUND:It is known that antimalarial drugs reduce the risk of low birth weight (LBW) in pregnant patients. However, a previous Cochrane review did not evaluate whether the level of antimalarial drug resistance could modify the protective effect of antimalarial drugs in this regard. In addition, no systematic review...

journal_title：BMC medicine

authors： Muanda FT,Chaabane S,Boukhris T,Santos F,Sheehy O,Perreault S,Blais L,Bérard A

更新日期：2015-08-14 00:00:00