Abstract:
:Aortic stenosis is the most common valvular heart disease in the developed world. About 7% of the population over age 65 years suffers from degenerative aortic stenosis. The prognosis of patients with symptomatic severe aortic stenosis is dismal without valve replacement. Even though the American College of Cardiology recommends aortic valve replacement to treat this condition as a class I recommendation, approximately one third of these patients over the age of 75 years are not referred for surgery. Typically, this is from concern about prohibitive surgical risk associated with patient frailty, comorbidities, age, and severe left ventricular dysfunction. The advent in France of transcatheter aortic valve replacement has raised the hope in the United States for an alternative, less invasive treatment for aortic stenosis. Two recent trials-the Placement of AoRTic TraNscathetER Valve Trial Edwards SAPIEN Transcatheter Heart Valve (Partner) and the CoreValve US Pivotal-have established transcatheter aortic valve replacement as the preferred approach in patients who are at high or prohibitive surgical risk. The more recently published Partner 2 trial has shown the feasibility of transcatheter aortic valve replacement in intermediate-surgical-risk patients as well. With a profile that promises easier use and better valve performance and delivery, newer-generation valves have shown their potential for further improvement in safety profile and overall outcomes. We review the history and status of this topic.
journal_name
Tex Heart Inst Jjournal_title
Texas Heart Institute journalauthors
Arora S,Misenheimer JA,Ramaraj Rdoi
10.14503/THIJ-16-5852subject
Has Abstractpub_date
2017-02-01 00:00:00pages
29-38issue
1eissn
0730-2347issn
1526-6702journal_volume
44pub_type
历史文章,杂志文章,评审abstract::In this study, we retrospectively analyzed the outcomes of adults with bicuspid aortic valve (BAV) disease who underwent aortic valve reconstructive surgery (AVRS), consisting of replacement of the diseased BAV with 2 or 3 pericardial leaflets plus fixation of the sinotubular junction for accurate and constant leaflet...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
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journal_title:Texas Heart Institute journal
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journal_title:Texas Heart Institute journal
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journal_title:Texas Heart Institute journal
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journal_title:Texas Heart Institute journal
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journal_title:Texas Heart Institute journal
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journal_title:Texas Heart Institute journal
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journal_title:Texas Heart Institute journal
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journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
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journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
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journal_title:Texas Heart Institute journal
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doi:
更新日期:2006-01-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Texas Heart Institute journal
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doi:
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journal_title:Texas Heart Institute journal
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journal_title:Texas Heart Institute journal
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journal_title:Texas Heart Institute journal
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