Electrophysiology of Hypothalamic Magnocellular Neurons In vitro: A Rhythmic Drive in Organotypic Cultures and Acute Slices.

abstract：:There are few behavioral effects as ubiquitous as the speed-accuracy tradeoff (SAT). From insects to rodents to primates, the tendency for decision speed to covary with decision accuracy seems an inescapable property of choice behavior. Recently, the SAT has received renewed interest, as neuroscience approaches begin ...

journal_title：Frontiers in neuroscience

authors： Heitz RP

更新日期：2014-06-11 00:00:00

abstract：:Brain functional connectivity network (BFCN) analysis has been widely used in the diagnosis of mental disorders, such as schizophrenia. In BFCN methods, brain network construction is one of the core tasks due to its great influence on the diagnosis result. Most of the existing BFCN construction methods only consider t...

journal_title：Frontiers in neuroscience

authors： Zhu Q,Li H,Huang J,Xu X,Guan D,Zhang D

更新日期：2019-06-14 00:00:00

abstract：:Anesthetized rodent models are ubiquitous in pre-clinical neuroimaging studies. However, because the associated cerebral morphology and experimental methodology results in a profound negative brain-core temperature differential, cerebral temperature changes during functional activation are likely to be principally dri...

journal_title：Frontiers in neuroscience

authors： Harris SS,Boorman LW,Das D,Kennerley AJ,Sharp PS,Martin C,Redgrave P,Schwartz TH,Berwick J

更新日期：2018-08-14 00:00:00

abstract：:We describe the steps involved in analysis of multi-modal, multi-subject human neuroimaging data using the SPM12 free and open source software (https://www.fil.ion.ucl.ac.uk/spm/) and a publically-available dataset organized according to the Brain Imaging Data Structure (BIDS) format (https://openneuro.org/datasets/ds...

journal_title：Frontiers in neuroscience

authors： Henson RN,Abdulrahman H,Flandin G,Litvak V

更新日期：2019-04-24 00:00:00

abstract：:Oxylipins are a series of bioactive lipid metabolites derived from polyunsaturated fatty acids that are involved in cerebral homeostasis and the development of intracerebral hemorrhage (ICH). However, comprehensive quantification of the oxylipin profile in ICH remains unknown. Therefore, an ICH mouse model was constru...

journal_title：Frontiers in neuroscience

authors： Yuan JJ,Chen Q,Xiong XY,Zhang Q,Xie Q,Huang JC,Yang GQ,Gong CX,Qiu ZM,Sang HF,Zi WJ,He Q,Xu R,Yang QW

更新日期：2020-09-23 00:00:00

abstract：:Diabetic neuropathy (DPN) is one of the most severe and yet most poorly understood complications of diabetes mellitus. In vivo imaging of dorsal root ganglia (DRG), a key structure for the understanding of DPN, has been restricted to animal studies. These have shown a correlation of decreased DRG volume with neuropath...

journal_title：Frontiers in neuroscience

authors： Jende JME,Kender Z,Rother C,Alvarez-Ramos L,Groener JB,Pham M,Morgenstern J,Oikonomou D,Hahn A,Juerchott A,Kollmer J,Heiland S,Kopf S,Nawroth PP,Bendszus M,Kurz FT

更新日期：2020-09-25 00:00:00

abstract：:Speech perception under audiovisual (AV) conditions is well known to confer benefits to perception such as increased speed and accuracy. Here, we investigated how AV training might benefit or impede auditory perceptual learning of speech degraded by vocoding. In Experiments 1 and 3, participants learned paired associa...

journal_title：Frontiers in neuroscience

authors： Bernstein LE,Auer ET Jr,Eberhardt SP,Jiang J

更新日期：2013-03-18 00:00:00

abstract：:Spatial group independent component analysis (GICA) methods decompose multiple-subject functional magnetic resonance imaging (fMRI) data into a linear mixture of spatially independent components (ICs), some of which are subsequently characterized as brain functional networks. Group information guided independent compo...

journal_title：Frontiers in neuroscience

authors： Du Y,Lin D,Yu Q,Sui J,Chen J,Rachakonda S,Adali T,Calhoun VD

更新日期：2017-05-19 00:00:00

abstract：:Alzheimer disease (AD) and vascular dementia (VaD) together represent the majority of dementia cases. Since their neuropsychological profiles often overlap and white matter lesions are observed in elderly subjects including AD, differentiating between VaD and AD can be difficult. Characterization of these different fo...

journal_title：Frontiers in neuroscience

authors： Palesi F,De Rinaldis A,Vitali P,Castellazzi G,Casiraghi L,Germani G,Bernini S,Anzalone N,Ramusino MC,Denaro FM,Sinforiani E,Costa A,Magenes G,D'Angelo E,Gandini Wheeler-Kingshott CAM,Micieli G

更新日期：2018-04-25 00:00:00

abstract：:Despite decades of research, current therapeutic interventions for Parkinson's disease (PD) are insufficient as they fail to modify disease progression by ameliorating the underlying pathology. Cellular proteostasis (protein homeostasis) is an essential factor in maintaining a persistent environment for neuronal activ...

journal_title：Frontiers in neuroscience

authors： Lehtonen Š,Sonninen TM,Wojciechowski S,Goldsteins G,Koistinaho J

更新日期：2019-05-10 00:00:00

abstract：:A patient with early achalasia presented spontaneous strong rhythmic non-propulsive contractions at ~7/min, independent of swallows. Our aim was to evaluate characteristics of the rhythmic contractions, provide data on the structure of pacemaker cells in the esophagus and discuss a potential role for interstitial cell...

journal_title：Frontiers in neuroscience

authors： Chen JH,Wang XY,Liu LW,Yu W,Yu Y,Zhao L,Huizinga JD

更新日期：2013-05-21 00:00:00

abstract：:The present study interrogated a quantitative trait locus (QTL) on Chr 4 associated with the population sizes of two types of bipolar cell in the mouse retina. This locus was identified by quantifying the number of rod bipolar cells and Type 2 cone bipolar cells across a panel of recombinant inbred (RI) strains of mic...

journal_title：Frontiers in neuroscience

authors： Kautzman AG,Keeley PW,Ackley CR,Leong S,Whitney IE,Reese BE

更新日期：2018-12-03 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) is increasingly used in both research and therapeutic settings, but its precise mechanisms remain largely unknown. At a neuronal level, tDCS modulates cortical excitability by shifting the resting membrane potential in a polarity-dependent way: anodal stimulation increase...

journal_title：Frontiers in neuroscience

authors： Varoli E,Pisoni A,Mattavelli GC,Vergallito A,Gallucci A,Mauro LD,Rosanova M,Bolognini N,Vallar G,Romero Lauro LJ

更新日期：2018-05-15 00:00:00

abstract：:Wireless electroencephalography (EEG) of small animal subjects typically utilizes miniaturized EEG devices which require a robust recording and electrode assembly that remains in place while also being well-tolerated by the animal so as not to impair the ability of the animal to perform normal living activities or exp...

journal_title：Frontiers in neuroscience

authors： Vogler EC,Flynn DT,Busciglio F,Bohannan RC,Tran A,Mahavongtrakul M,Busciglio JA

更新日期：2017-11-14 00:00:00

abstract：:Recent progress in tissue engineering has led to increasingly complex approaches to investigate human neurodegenerative diseases in vitro, such as Alzheimer's disease, aiming to provide more functional and physiological models for the study of their pathogenesis, and possibly the identification of novel diagnostic bio...

journal_title：Frontiers in neuroscience

authors： Brighi C,Cordella F,Chiriatti L,Soloperto A,Di Angelantonio S

更新日期：2020-06-17 00:00:00

abstract：:Monoamine oxidase-A (MAO-A) and MAO-B have both been implicated in the pathology of Alzheimer disease (AD). We examined 60 autopsied control and AD donor brain samples to determine how well MAO function aligned with two major risk factors for AD, namely sex and APOE ε4 status. MAO-A activity was increased in AD cortic...

journal_title：Frontiers in neuroscience

authors： Quartey MO,Nyarko JNK,Pennington PR,Heistad RM,Klassen PC,Baker GB,Mousseau DD

更新日期：2018-06-26 00:00:00

abstract：:Whereas major insights into the neuronal basis of adaptive behavior have been gained from the study of automatic behaviors, including reflexive and rhythmic motor acts, the neural substrates for goal-directed behaviors in which decision-making about action selection and initiation are crucial, remain poorly understood...

journal_title：Frontiers in neuroscience

authors： Nargeot R,Simmers J

更新日期：2012-07-26 00:00:00

abstract：:Nocturnal secretion of melatonin from the pineal gland may affect central and peripheral timing, in addition to its well-known involvement in the control of seasonal physiology. The Syrian hamster is a photoperiodic species, which displays gonadal atrophy and increased adiposity when adapted to short (winter-like) pho...

journal_title：Frontiers in neuroscience

authors： Chakir I,Dumont S,Pévet P,Ouarour A,Challet E,Vuillez P

更新日期：2015-05-27 00:00:00

abstract：:Neuromorphic computing employs models of neuronal circuits to solve computing problems. Neuromorphic hardware systems are now becoming more widely available and "neuromorphic algorithms" are being developed. As they are maturing toward deployment in general research environments, it becomes important to assess and com...

journal_title：Frontiers in neuroscience

authors： Diamond A,Nowotny T,Schmuker M

更新日期：2016-01-08 00:00:00

abstract：:Here, we present the first description of an isolation syndrome in a patient who suffered prolonged cardiac arrest and underwent a standard therapeutic hypothermia protocol. Two years after the arrest, the patient demonstrated no motor responses to commands, communication capabilities, or visual tracking at the bedsid...

journal_title：Frontiers in neuroscience

authors： Forgacs PB,Fridman EA,Goldfine AM,Schiff ND

更新日期：2016-06-09 00:00:00

abstract：:Antimicrobial peptides (AMPs) are promising next generation antibiotics that hold great potential for combating bacterial resistance. AMPs can be both bacteriostatic and bactericidal, induce rapid killing and display a lower propensity to develop resistance than do conventional antibiotics. Despite significant progres...

journal_title：Frontiers in neuroscience

authors： Li J,Koh JJ,Liu S,Lakshminarayanan R,Verma CS,Beuerman RW

更新日期：2017-02-14 00:00:00

abstract：:A recent report claims that functional brain networks defined with resting-state functional magnetic resonance imaging (fMRI) can be recapitulated with correlated gene expression (i.e., high within-network tissue-tissue "strength fraction," SF) (Richiardi et al., 2015). However, the authors do not adequately control f...

journal_title：Frontiers in neuroscience

authors： Pantazatos SP,Li X

更新日期：2017-07-18 00:00:00

abstract：:Value-based decision making relies on distributed neural systems that weigh the benefits of actions against the cost required to obtain a given outcome. Perturbations of these systems are thought to underlie abnormalities in action selection seen across many neuropsychiatric disorders. Genetic tools in mice provide a ...

journal_title：Frontiers in neuroscience

authors： Alabi OO,Fortunato MP,Fuccillo MV

更新日期：2019-02-07 00:00:00

abstract：:Vagus nerve stimulation (VNS) therapy is associated with laryngeal muscle activation and induces voice modifications, well-known side effects of the therapy resulting from co-activation of the recurrent laryngeal nerve. In this study, we describe the non-invasive transcutaneous recording of laryngeal motor evoked pote...

journal_title：Frontiers in neuroscience

authors： Vespa S,Stumpp L,Bouckaert C,Delbeke J,Smets H,Cury J,Ferrao Santos S,Rooijakkers H,Nonclercq A,Raedt R,Vonck K,El Tahry R

更新日期：2019-08-27 00:00:00

abstract：:The structure of gene coexpression networks reflects the activation and interaction of multiple cellular systems. Since the pathology of neuropsychiatric disorders is influenced by diverse cellular systems and pathways, we investigated gene coexpression networks in major depression, and searched for putative unifying ...

journal_title：Frontiers in neuroscience

authors： Gaiteri C,Sibille E

更新日期：2011-08-30 00:00:00

abstract：:Beside diverse therapeutic properties of palmitoylethanolamide (PEA) including: neuroprotection, inflammation and pain alleviation, prophylactic effects have also been reported in animal models of infections, inflammation, and neurological diseases. The availability of PEA as (ultra)micronized nutraceutical formulatio...

journal_title：Frontiers in neuroscience

authors： Lerner R,Pascual Cuadrado D,Post JM,Lutz B,Bindila L

更新日期：2019-06-11 00:00:00

abstract：:L-DOPA-induced dyskinesia (LID) represents one of the major problems of the long-term therapy of patients with Parkinson's disease (PD). Although, the pathophysiologic mechanisms underlying LID are not completely understood, activation of the extracellular signal regulated kinase (ERK) is recognized to play a key role...

journal_title：Frontiers in neuroscience

authors： Chen G,Nie S,Han C,Ma K,Xu Y,Zhang Z,Papa SM,Cao X

更新日期：2017-03-09 00:00:00

abstract：:Up to 50% of traumatic brain injury (TBI) survivors demonstrate persisting and late-onset anxiety disorders indicative of limbic system dysregulation, yet the pathophysiology underlying the symptoms is unclear. We hypothesize that the development of TBI-induced anxiety-like behavior in an experimental model of TBI is ...

journal_title：Frontiers in neuroscience

authors： Beitchman JA,Griffiths DR,Hur Y,Ogle SB,Bromberg CE,Morrison HW,Lifshitz J,Adelson PD,Thomas TC

更新日期：2020-01-21 00:00:00

abstract：:D-norpseudoephedrine (NPE), also known as cathine, is found naturally in the shrub Catha edulis "Khat." NPE has been widely used as an appetite suppressant for the treatment of obesity. Although it is known that NPE acts on α1-adrenergic receptors, there is little information about the role of dopamine receptors on NP...

journal_title：Frontiers in neuroscience

authors： Kalyanasundar B,Perez CI,Arroyo B,Moreno MG,Gutierrez R

更新日期：2020-10-16 00:00:00

abstract：:The Iowa Gambling Task (IGT) has been widely used to assess differences in decision-making under uncertainty. Recently, several studies have shown that healthy subjects do not meet the basic predictions of the task (i.e., prefer options with positive long-term outcome), hence questioning its basic assumptions. Since c...

journal_title：Frontiers in neuroscience

authors： Horstmann A,Villringer A,Neumann J

更新日期：2012-05-14 00:00:00