High protein supplementation in pregnancy.

Abstract:

OBJECTIVES:To assess the effects of providing pregnant women with high-protein nutritional supplements on gestational weight gain and on the outcome of pregnancy, including fetal growth, gestational duration, and maternal and fetal/infant morbidity and mortality. SEARCH STRATEGY:The register of clinical trials maintained and updated by the Cochrane Pregnancy and Childbirth Group. SELECTION CRITERIA:All acceptably controlled comparisons of protein/energy supplementation in which the protein content of the supplement provided >25% of its total energy content. DATA COLLECTION AND ANALYSIS:Data were extracted by the author from published reports, and supplemented by additional information from trialists contacted by the author. MAIN RESULTS:Two studies involving 1076 women were included. High protein supplementation was associated with a small, statistically nonsignificant increase in weekly maternal weight gain. The two available trials provide no evidence of benefit on fetal growth; indeed, the adjusted mean difference in birth weight is -58. 4 g. One trial also reported a nonsignificantly increased risk of neonatal death with high-protein supplementation. REVIEWER'S CONCLUSIONS:There is not enough evidence to evaluate the use of high protein supplementation in pregnancy.

authors

Kramer MS

doi

10.1002/14651858.CD000105

keywords:

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

CD000105

issue

2

issn

1469-493X

pii

CD000105

pub_type

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