Abstract：
:We have reviewed the clinical presentations, courses, and outcomes of 90 patients seen at Texas Children's Hospital from 1983 through 2008 who had an isolated cleft of the mitral valve without some form of endocardial cushion defect. Additional congenital cardiac defects were present in 61 of the 90 patients, 35 of whom had a congenital syndrome. Seven patients had isolated cleft of the mitral valve without other intracardiac defects, and in these 7 there was a progressive increase in the degree of mitral regurgitation during a median time of 26.5 months from diagnosis to surgery. The patients ranged from a gestational age of approximately 32 weeks to 21.9 years of age. No death was observed among the 39 surgical patients, including 32 who had additional cardiac defects. There was a significant reduction in the degree of mitral regurgitation in all patients who underwent surgery. Among the 51 patients who did not have surgery, the degree of regurgitation did not change significantly over the course of 1 to 27 years' observation. Isolated cleft of the mitral valve is an uncommon (but not rare) congenital malformation of the mitral valve that can cause all degrees of mitral regurgitation but can be managed medically or surgically.
journal_name
Tex Heart Inst Jjournal_title
Texas Heart Institute journalauthors
Zhu D,Bryant R,Heinle J,Nihill MRsubject
Has Abstractpub_date
2009-01-01 00:00:00pages
553-6issue
6eissn
0730-2347issn
1526-6702journal_volume
36pub_type
杂志文章abstract：:Between May 1976 and December 1982 (104 months), 152 patients from a total of 3592 patients who had coronary angiography at the Buffalo Veterans Administration Medical Center had coronary artery disease with left ventricular ejection fractions of 40% or below. Sixty-three patients in this group had coronary bypass sur...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1986-03-01 00:00:00
abstract：:We report the case of a 65-year-old man with a 6-year history of hypertension who presented with dilated cardiomyopathy, a transient cerebrovascular event, paroxysmal sweating, and intractable hypertension. Coronary angiography revealed no abnormality, but diagnostic testing was pursued because of the severe sweating ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：:This report describes the case of a 61-year-old woman who presented with dyspnea, aortic stenosis, and coronary artery disease-typical side effects of radiation therapy for Hodgkin lymphoma. A poor candidate for surgery, she underwent successful high-risk percutaneous coronary intervention and subsequent transcatheter...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：10.14503/THIJ-16-5806
更新日期：2016-08-01 00:00:00
abstract：:Paleopathology, the study of disease in ancient remains, adds the dimension of time to our study of health and disease. The oldest preserved heart is from a mummified rabbit of the Pleistocene epoch, over 20,000 years old. Cardiovascular disease has been identified in human mummies from Alaska and Egypt, covering a ti...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Atrioventricular septal defects represent a class of congenital cardiac malformations that vary in presentation and management strategy depending upon the severity of the particular lesions present. We present the case of a premature neonate who had a partial atrioventricular septal defect and an accessory mitral (or ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：10.14503/THIJ-15-5675
更新日期：2016-12-01 00:00:00
abstract：:A conservative nonoperative method of management was utilized in an atypical case of blunt traumatic rupture of the thoracic aorta. In unusual or complicated tears of the aortic arch, as described here, a delayed or expectant method of management may be justified. ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1982-09-01 00:00:00
abstract：:The surface electrocardiogram can be simply described as the P, QRS, and T (and U) waves, together with PR and ST segments. However, it is actually the summation of the action potential from the sinoatrial node, the atria, the atrioventricular node, the His-Purkinje system, and the ventricles. Although the action pote...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：:Sixty consecutive patients undergoing elective open-heart surgery were prospectively enrolled in a study to compare the efficacy of 3 different antifibrinolytic drugs to reduce postoperative bleeding and to reduce homologous blood requirements in combination with blood-saving techniques and restrictive indications for...
journal_title：Texas Heart Institute journal
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-01-01 00:00:00
abstract：:The central question that faces coronary laser investigators is whether interaction between laser energy and target tissues can be controlled in a dynamic in vivo environment. In considering this question, the author reviews the in vitro and in vivo experiments that his center carried out before it began using laser a...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Acquired long QT syndrome is typically caused by medications, electrolyte disturbances, bradycardia, or catastrophic central nervous system events. We report a case of myocardial infarction-related acquired long QT syndrome in a 58-year-old woman that had no clear cause and progressed to torsades de pointes requiring ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：10.14503/THIJ-18-6872
更新日期：2020-04-01 00:00:00
abstract：:Postoperative tricuspid valve regurgitation is moderate to severe in 15% to 20% of heart transplant recipients despite use of the bicaval surgical technique. We hypothesized that the regurgitation might be partly due to increased tension on the donor right atrium. To study the right atrial distortion, we modified the ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：:Juxtarenal abdominal aortic aneurysms (AAAs) are difficult to treat because they often have little or no proximal aortic neck. Patients with this complex anatomy are not usually candidates for an endovascular aneurysm repair (EVAR). Chimney-graft EVAR has been introduced, but type Ia endoleak is a typical risk. We hav...
journal_title：Texas Heart Institute journal
pub_type：
doi：10.14503/THIJ-17-6520
更新日期：2019-06-01 00:00:00
abstract：:The introduction of percutaneous ablative treatments for atrial fibrillation led to new information regarding the region of the left atrium and pulmonary veins, which electrophysiologists had previously overlooked. Initially, procedures for treating atrial fibrillation involved ablation and then the isolation of speci...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:In this study, we retrospectively analyzed the outcomes of adults with bicuspid aortic valve (BAV) disease who underwent aortic valve reconstructive surgery (AVRS), consisting of replacement of the diseased BAV with 2 or 3 pericardial leaflets plus fixation of the sinotubular junction for accurate and constant leaflet...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：10.14503/THIJ-13-3619
更新日期：2014-12-01 00:00:00
abstract：:One-stage surgery was successfully performed in a 44-year-old hypertensive man with uncontrolled angina, multiple coarctations of the thoracic and abdominal aorta, and a previous subtotal gastrectomy. There was a gradient of 120 mm Hg between the thoracic and abdominal aorta. A graft was placed retroperitoneally from ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1985-06-01 00:00:00
abstract：:We describe the case of a young woman with Takayasu's arteritis that initially manifested as heart failure due to left main coronary artery stenosis. The patient's occluded subclavian artery and the active inflammatory process of Takayasu's arteritis precluded coronary artery bypass grafting with the use of arterial g...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:The number of cancer survivors in the United States has exceeded 12 million and is increasing. After secondary malignancies, cardiovascular disease is the leading cause of late morbidity and death among cancer survivors. The cardiovascular needs of cancer survivors have not been described. We describe the clinical cha...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:We operated on a 14-year-old boy who had an echocardiographic diagnosis of ventricular septal defect. At surgery we found, in addition, an anomalous and obstructive intraventricular muscle bundle. Detection of a continuous thrill over the right pulmonary veins, prior to cardiopulmonary bypass, led to exploration of th...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:We report a patient who sustained a myocardial infarction after inhaling cocaine. He developed a persistent wall motion defect that was present 18 months after the acute event despite resolution of electrocardiographic evidence of infarction. ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1985-12-01 00:00:00
abstract：:Pseudoaneurysms of the ascending aorta after the original inclusion/wrap technique of the Bentall procedure present a difficult surgical management problem and are associated with substantial morbidity and mortality. Patients with Marfan syndrome frequently develop aneurysms and dissections that involve multiple aorti...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:Contrast echocardiography is recognized to be a safe, effective technique for evaluating the endocardial border and left ventricular function in patients who have suboptimal non-contrast echocardiograms. However, its use in diagnosing right-heart conditions is less well established. Herein, we report our experience wi...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
abstract：:Interventionalists encounter widely different coronary anatomies during left main coronary artery stenting. Optimal percutaneous coronary intervention in left main disease necessitates stents that achieve adequate apposition and adapt to frequently disparate diameters in the same lesion, without the need for overexpan...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：10.14503/THIJ-17-6190
更新日期：2017-10-01 00:00:00
abstract：:We present a case of aortic valve replacement combined with aortic root enlargement, performed on an achondroplastic dwarf with severe calcific aortic stenosis. There are no data about the incidence of valvular diseases in achondroplastic patients. To our knowledge, this is the 1st time that an aortic valve replacemen...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:Disease or dysfunction of the aortic valve in pediatric patients presents a substantial challenge. Valve preservation, even if not the definitive solution, is always optimal. Successful repair will enable somatic growth and avoid repeated valve replacement and the need for systemic anticoagulation. When repair of the ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:From 1956 through July 1981, 15 patients, ranging in age from 9 days to 20 years, underwent surgical correction of aortopulmonary (AP) window. Surface hypothermia and venous inflow occlusion were used in the first patient. In four patients, the technique for closure of AP window was similar to that for patent ductus a...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1983-03-01 00:00:00
abstract：:Orthoclone OKT3 (muromonab-CD3), a murine monoclonal antibody that virtually eliminates circulating T cells and inhibits medullary lymphocyte function, has recently been found effective in reversing stubborn severe allograft rejection after heart transplantation. To determine the influence of OKT3 therapy on the devel...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:Aneurysms of the axillary artery are rare and dangerous lesions that threaten the upper extremities with vascular and neurologic compromise. Most can be treated effectively with surgical excision and vascular grafting. We retrospectively assessed 4 axillary artery aneurysms upon which we operated from February 1998 th...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:In pulmonary arterial hypertension, the blood vessels that carry blood between the heart and lungs are constricted, making it difficult for the heart to pump blood through the lungs. Prostacyclin, a prostanoid metabolized from endogenous arachidonic acid through the cyclooxygenase (COX) pathway, is a potent vasodilato...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章,评审
doi：
更新日期：2010-01-01 00:00:00
abstract：:In conclusion, reduced nitric oxide bioactivity contributes to cardiac and vascular remodeling. Nitricoxide-enhancing therapy can slow cardiac andvascular remodeling. African-Americans with heart failure exhibit nitric oxide deficiency and a dramatic benefit from nitric-oxide-enhancing therapy. The potential benefit o...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章,评审
doi：
更新日期：2005-01-01 00:00:00
abstract：:We prospectively compared closure and complication rates in 91 children with secundum atrial septal defects: 44 (mean age, 8.1 +/- 4.7 years) were treated surgically and 47 (mean age, 10.1 +/- 4.9 years) were treated by percutaneous Amplatzer septal occluder Complications were classified as mild, moderate, or severe. ...
journal_title：Texas Heart Institute journal
pub_type： 临床试验,杂志文章
doi：
更新日期：2004-01-01 00:00:00
