QTc interval prolongation predicts postoperative mortality in heart failure patients undergoing surgical revascularization.

Abstract:

:QTc interval prolongation is associated with increased mortality rates in patients with advanced heart failure. We investigated the predictive value of prolonged QTc interval in 567 patients with heart failure who were undergoing coronary artery bypass graft surgery The patients were in New York Heart Association class III or IV, with left ventricular ejection fractions of 0.40 or less. Before surgery, the QT interval duration was measured in leads II and V4 of the standard electrocardiogram and corrected by use of the Bazett formula. The QTc interval was prolonged (>440 msec) in 243 patients (43%) and normal in 324 (57%). The 2 study groups--prolonged QTc versus normal QTc--did not differ in terms of age (62 +/- 11 years vs 64 +/- 10 years, P=0.65), sex (80% male vs 76% male, P=0.31), ejection fraction (0.29 +/- 0.08 vs 0.29 +/- 0.09, P=0.72), hypertension (82% vs 78%, P=0.34), or diabetes (11% vs 7%, P=0.10). Within 1 month after coronary artery bypass grafting, 22 of 243 patients (9.1%) in the prolonged QTc group died, compared with 5 of 324 in the normal QTc group (1.5%) (P=0.0001). QTc interval prolongation was the only independent predictor of postoperative mortality on multivariate analysis (P=0.002). We conclude that patients with heart failure and preoperative QTc interval prolongation have increased mortality rates after coronary artery bypass grafting.

journal_name

Tex Heart Inst J

authors

Vrtovec B,Ryazdanbakhsh AP,Pintar T,Collard CD,Gregoric ID,Radovancevic B

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

3-8

issue

1

eissn

0730-2347

issn

1526-6702

journal_volume

33

pub_type

杂志文章
  • Contemporary treatment of unstable angina and non-ST-segment-elevation myocardial infarction (part 2).

    abstract::In Part 1 of this review, we discussed how plaque rupture is the most common underlying cause of most cases of unstable angina/non-ST-segment-elevation myocardial infarction (UA/NSTEMI) and how early risk stratification is vital for the timely diagnosis and treatment of acute coronary syndromes (ACS). Now, in Part 2, ...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章,评审

    doi:

    authors: Sami S,Willerson JT

    更新日期:2010-01-01 00:00:00

  • Atrial sounds and endocardial electrograms recorded during coarse atrial fibrillation.

    abstract::Hearing atrial sounds is unusual during atrial flutter and rare during atrial fibrillation. We report a patient with hypertrophic cardiomyopathy and coarse atrial fibrillation in whom atrial sounds were recorded phonocardiographically during endocardial atrial electrography. The atrial sounds were recorded phonocardio...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Hill PE,Amos L,Haines DE

    更新日期:1991-01-01 00:00:00

  • Glucose-6-Phosphate Dehydrogenase Deficiency is Associated with Cardiovascular Disease in U.S. Military Centers.

    abstract::Glucose-6-phosphate dehydrogenase (G6PD) protects erythrocytes from oxidative stress and hemolysis; G6PD deficiency is the most prevalent enzymopathy. The United States military routinely performs tests to prevent exposing G6PD-deficient personnel to antimalarial drugs that might cause life-threatening hemolytic react...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章,多中心研究

    doi:10.14503/THIJ-16-6052

    authors: Thomas JE,Kang S,Wyatt CJ,Kim FS,Mangelsdorff AD,Weigel FK

    更新日期:2018-06-01 00:00:00

  • Matrix metalloproteinase-1 and tissue inhibitors do not predict incident coronary artery disease in the atherosclerosis risk in communities (ARIC) study.

    abstract::Matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) are thought to be associated with coronary artery disease. The association of these markers with incident coronary artery disease has not been well described. Using a case-cohort design, we selected 216 individuals who had inci...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Nambi V,Morrison AC,Hoogeveen RC,Coresh J,Miles S,Rhodes CE,Sharrett AR,Boerwinkle BE,Ballantyne CM

    更新日期:2008-01-01 00:00:00

  • Bronchogenic cyst.

    abstract::The clinical presentation of the bronchogenic cyst is variable, from respiratory distress at birth to late appearance of symptoms. In order to determine clinical features and treatments, we retrospectively studied the medical records and pathology reports of all patients with bronchogenic cysts (n = 22) referred to ou...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Sarper A,Ayten A,Golbasi I,Demircan A,Isin E

    更新日期:2003-01-01 00:00:00

  • Intracardiac metastatic melanoma: report of a case mimicking a right atrial myxoma, with a review of the literature.

    abstract::A 49-year-old patient, referred with a diagnosis of right atrial myxoma, was found at surgery to have extensive cardiac metastases from a previously undetected cutaneous melanoma. In reviewing the literature, we found 5 other patients with a clinical diagnosis of melanoma metastatic to the heart, all of whom had a pre...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Bortolotti U,Tursi V,Milano A,Mazzucco A,Gallucci V

    更新日期:1990-01-01 00:00:00

  • Coronary heart disease at altitude.

    abstract::In the past, it has been assumed that some basic physiologic responses to altitude, exposure in coronary patients are comparable to those in normal young subjects. In fact there are similar changes in sympathetic activation, heart rate, and blood pressure early after ascent, with decrements in plasma volume, cardiac o...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章,评审

    doi:

    authors: Alexander JK

    更新日期:1994-01-01 00:00:00

  • Changes in Coronary Plaque Volume: Comparison of Serial Measurements on Intravascular Ultrasound and Coronary Computed Tomographic Angiography.

    abstract::Serial measurements of coronary plaque volume have been used to evaluate drug efficacy in atherosclerotic progression. However, the usefulness of computed tomography for this purpose is unknown. We investigated whether the change in total plaque volume on coronary computed tomographic angiography is associated with th...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:10.14503/THIJ-15-5212

    authors: Nakanishi R,Alani A,Matsumoto S,Li D,Fahmy M,Abraham J,Dailing C,Broersen A,Kitslaar PH,Nasir K,Min JK,Budoff MJ

    更新日期:2018-04-07 00:00:00

  • Myocardial dysplasia in a 3rd-trimester fetus. An ultrasound and pathologic study.

    abstract::Arrested myocardial development, often described as spongiosum heart, has been reported in association with obstructive semilunar valve disease and, much more rarely, as a primary disease in adolescents and adults. To our knowledge, this condition has never been diagnosed in utero. We describe the echocardiographic an...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Paladini D,Russo M,Palmieri S,Pacileo G,Caruso G,Ianniruberto A,Martinelli P,Calabrò R

    更新日期:1997-01-01 00:00:00

  • Aortic valve reconstruction with use of pericardial leaflets in adults with bicuspid aortic valve disease: early and midterm outcomes.

    abstract::In this study, we retrospectively analyzed the outcomes of adults with bicuspid aortic valve (BAV) disease who underwent aortic valve reconstructive surgery (AVRS), consisting of replacement of the diseased BAV with 2 or 3 pericardial leaflets plus fixation of the sinotubular junction for accurate and constant leaflet...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:10.14503/THIJ-13-3619

    authors: Song MG,Yang HS,Choi JB,Shin JK,Chee HK,Kim JS

    更新日期:2014-12-01 00:00:00

  • Intraaortic balloon counterpulsation: an eleven-year review and analysis of determinants of survival.

    abstract::During an 11-year period ending January 1, 1985, 352 patients had insertions of an intraaortic balloon pump (IABP) as an adjunct to medical or surgical therapy. Group I, 175 patients, could not be weaned from cardiopulmonary bypass and required intraaortic balloon pump (IABP). Thirty-nine patients (22%) died in the op...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Corral CH,Vaughn CC

    更新日期:1986-03-01 00:00:00

  • Early degeneration of porcine xenograft valves in pediatric patients who have undergone apico-aortic bypass.

    abstract::The glutaraldehyde-preserved stented porcine xenograft valve has been durable in adult patients with a low incidence of valve-related complications. In children, however, early degeneration and calcification of this valve is now being reported. The etiology of the early degeneration is still unclear but may be related...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Chen R,Duncan JM,Nihill M,Cooley DA

    更新日期:1982-03-01 00:00:00

  • Repair of total anomalous pulmonary venous return: results after 47 years.

    abstract::We present herein the case of a 48-year-old patient who had undergone repair of total anomalous pulmonary venous return at the age of 14 months, in March 1960, at Texas Children's Hospital. When this patient voluntarily underwent re-examination in 2007, echocardiography revealed the late results of surgery that had be...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Cooley DA,Cabello OV,Preciado FM

    更新日期:2008-01-01 00:00:00

  • Two cases of apical ballooning syndrome masking apical hypertrophic cardiomyopathy.

    abstract::Apical akinesis and dilation in the absence of obstructive coronary artery disease is a typical feature of stress-induced (takotsubo) cardiomyopathy, whereas apical hypertrophy is seen in apical-variant hypertrophic cardiomyopathy. We report the cases of 2 patients who presented with takotsubo cardiomyopathy and were ...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:10.14503/THIJ-13-3191

    authors: Roy RR,Hakim FA,Hurst RT,Simper D,Appleton CP

    更新日期:2014-04-01 00:00:00

  • Pericardial effusion as an expression of thyrotoxicosis.

    abstract::Patients who have either hyperthyroidism or hypothyroidism can present with cardiovascular complications. These manifestations of thyroid disease-congestive heart failure, atrial tachyarrhythmias, atrioventricular conduction disorders, and mitral valve dysfunction-are well known to the clinician. Pericardial effusion ...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Ovadia S,Lysyy L,Zubkov T

    更新日期:2007-01-01 00:00:00

  • Initial experience with heart and lung transplantation.

    abstract::Between February 1983 and July 1987, twelve patients underwent heart-lung transplantation at the University of Cape Town and the University of Munich. The patients included eight men and four women, whose ages ranged from 15 to 49 years (mean, 27 years). The underlying pathologic condition was idiopathic primary pulmo...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Reichenspurner H,Odell JA,Cooper DK,Novitzky D,Rose AG,Klinner W,Reichart B

    更新日期:1988-01-01 00:00:00

  • Amiodarone for control of recurrent ventricular tachycardia secondary to cardiac metastasis.

    abstract::Metastatic tumors of the ventricles may cause symptomatic ventricular tachycardia such as described in this 66-year-old man, who presented with recurrent presyncope. The tumor may be readily diagnosed by 2-dimensional echocardiography, ultrafast computed tomography, or magnetic resonance imaging. Such tumors usually i...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Leak D

    更新日期:1998-01-01 00:00:00

  • Changing profile of infective endocarditis: a clinicopathologic study of 220 patients in a single medical center from 1998 through 2009.

    abstract::The epidemiologic profile of infective endocarditis has changed substantially over the past few years, especially in industrialized countries. Our study evaluates the clinical and pathologic characteristics of infective endocarditis patients treated by cardiac surgery in China during a 12-year period. We retrospective...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:10.14503/THIJ-13-3468

    authors: Li L,Wang H,Wang L,Pu J,Zhao H

    更新日期:2014-10-01 00:00:00

  • Accessory Mitral Valve Leaflet Causing Severe Left Ventricular Outflow Tract Obstruction in a Preterm Neonate with a Partial Atrioventricular Septal Defect.

    abstract::Atrioventricular septal defects represent a class of congenital cardiac malformations that vary in presentation and management strategy depending upon the severity of the particular lesions present. We present the case of a premature neonate who had a partial atrioventricular septal defect and an accessory mitral (or ...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:10.14503/THIJ-15-5675

    authors: Wilkes JK,Fraser CD,Seery TJ

    更新日期:2016-12-01 00:00:00

  • Partial anomalous pulmonary venous return: a ten-year experience.

    abstract::In this report, 24 patients with partial anomalous pulmonary venous return were reviewed. Six of the eight patients with left-sided drainage were repaired without extracorporeal circulation by anastomosing the left-sided vein to the left atrium. Symptoms resolved in five of the six. Two of the eight were surgically re...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Weiman DS,Lee K,Levett JM,Replogle RL

    更新日期:1985-09-01 00:00:00

  • Left Brachiocephalic Vein Cannulation in Bicaval Venous Drainage Is Safe, Effective, and Technically Advantageous.

    abstract::Direct cannulation of both venae cavae (bicaval venous cannulation) is the gold standard for right atrial isolation in intracavitary surgery, but there has been no consensus about an alternative site. Therefore, we studied an alternative method for bicaval venous drainage in which the left brachiocephalic vein (LBCV) ...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:10.14503/THIJ-14-4983

    authors: Aazami MH,Gholoobi A,Amini S,Abdollahi-Moghadam A,Soltani G

    更新日期:2016-04-01 00:00:00

  • Large left atrial myxoma with severe mitral regurgitation: the inverted T-shaped biatrial incision revisited.

    abstract::Cardiac myxomas are primary cardiac tumors. In some cases of atrial myxoma, the standard left atriotomy alone does not enable safe tumor resection and easy access to the mitral valve. We report the cases of 2 patients with huge left atrial myxomas associated with severe mitral valve regurgitation who underwent an inve...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Davoli G,Muzzi L,Lucchese G,Uricchio N,Chiavarelli M

    更新日期:2006-01-01 00:00:00

  • Atrial myxoma in a patient with hypertrophic cardiomyopathy.

    abstract::Atrial myxoma is the most common primary cardiac tumor. Patients with atrial myxoma typically present with obstructive, embolic, or systemic symptoms; asymptomatic presentation is very rare. To our knowledge, isolated association of atrial myxoma with hypertrophic cardiomyopathy has been reported only once in the Engl...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Abdou M,Hayek S,Williams BR 3rd

    更新日期:2013-01-01 00:00:00

  • Transcatheter aortic valve implantation through a left aortoiliac graft.

    abstract::The indications for transcatheter aortic valve implantation have been increasing with the development of new-generation valves and delivery systems. Our patient, an 81-year-old man with aortic stenosis, had an existing coronary artery bypass graft and bilateral aortoiliac bypass grafts. We used the transfemoral approa...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Gul M,Akgul O,Erturk M,Eksik A,Yildirim A

    更新日期:2012-01-01 00:00:00

  • The Two Anomalies of Wilhelm Ebstein.

    abstract::The year 2016 was the 180th anniversary of Wilhelm Ebstein's birth and the 150th anniversary of his description of the congenital tricuspid valve malformation that came to be known as Ebstein anomaly. We present a brief history of the life and work of Dr. Wilhelm Ebstein. Despite his distinguished career, he is seemin...

    journal_title:Texas Heart Institute journal

    pub_type: 传,历史文章,杂志文章,评审

    doi:10.14503/THIJ-16-6063

    authors: Mazurak M,Kusa J

    更新日期:2017-06-01 00:00:00

  • Latrogenic injury to the longthoracic nerve: an underestimated cause of morbidity after cardiac surgery.

    abstract::After heart surgery, complications affecting the brachial plexus have been reported in 2% to 38% of cases. The long thoracic nerve is vulnerable to damage at various levels, due to its long and superficial course. This nerve supplies the serratus anterior muscle, which has an important role in the abduction and elevat...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Bizzarri F,Davoli G,Bouklas D,Oncchio L,Frati G,Neri E

    更新日期:2001-01-01 00:00:00

  • Transcatheter retrieval of embolized AMPLATZER Septal Occluder.

    abstract::In selected patients, transcatheter closure of atrial septal defects with the AMPLATZER Septal Occluder has yielded excellent results. However, there is a slight risk of device embolization after deployment. We report the case of a 26-year-old woman in whom an embolized AMPLATZER device was retrieved percutaneously fr...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Goel PK,Kapoor A,Batra A,Khanna R

    更新日期:2012-01-01 00:00:00

  • Induction of early biomarkers in a thrombus-induced sheep model of ischemic heart failure.

    abstract::The levels of brain natriuretic peptide (BNP) and monocyte chemoattractant protein-1 (MCP-1) are known to be increased in the sera of subjects with heart failure. Existing models do not account for the biomass of thrombus that occurs in patients undergoing myocardial infarction. In this study, we compared the expressi...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Chandrakala AN,Kwiatkowski P,Sai-Sudhakar CB,Sun B,Phillips A,Parthasarathy S

    更新日期:2013-01-01 00:00:00

  • Cardiac resynchronization therapy as an adjunct to conventional surgical treatment for heart failure.

    abstract::From March 2004 through October 2007, we prospectively evaluated the benefits of cardiac resynchronization therapy as an adjunct to conventional procedures in patients who were undergoing surgery for heart failure.Twenty severely symptomatic patients (14 men and 6 women, with a mean age of 70 +/- 8 years) who displaye...

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:

    authors: Tesler UF,Lanzillo G,Novelli E,Cerin G,Diena M

    更新日期:2008-01-01 00:00:00

  • Regression of left ventricular mass after implantation of the sutureless 3f Enable aortic bioprosthesis.

    abstract::Left ventricular hypertrophy in aortic stenosis is considered a compensatory response for the maintenance of systolic function but a risk factor for cardiac morbidity and death. We investigated the degree of left ventricular mass regression after implantation of the sutureless Medtronic 3f Enable Aortic Bioprosthesis....

    journal_title:Texas Heart Institute journal

    pub_type: 杂志文章

    doi:10.14503/THIJ-13-3943

    authors: Concistrè G,Miceli A,Marchi F,Chiaramonti F,Glauber M,Solinas M

    更新日期:2015-04-01 00:00:00