Increased tartrate-resistant acid phosphatase (TRAP) expression in malignant breast, ovarian and melanoma tissue: an investigational study.

abstract：BACKGROUND:KIAA1199 is a recently identified novel gene that is up-regulated in human cancer with poor survival. Our proteomic study on signaling polarity in chemotactic cells revealed KIAA1199 as a novel protein target that may be involved in cellular chemotaxis and motility. In the present study, we examined the func...

journal_title：BMC cancer

authors： Jami MS,Hou J,Liu M,Varney ML,Hassan H,Dong J,Geng L,Wang J,Yu F,Huang X,Peng H,Fu K,Li Y,Singh RK,Ding SJ

更新日期：2014-03-15 00:00:00

abstract：BACKGROUND:A low cost and accurate method for detecting high-risk (HR) human papillomavirus (HPV) is important to permit HPV testing for cervical cancer prevention. We used a commercially available HPV method (H13, Hybribio) which was documented to function accurately in a reduced volume of cervical specimen to determi...

journal_title：BMC cancer

authors： Lou H,Gharzouzi E,Guerra SP,Fokom Domgue J,Sawitzke J,Villagran G,Garland L,Boland JF,Wagner S,Rosas H,Troxler J,McMillen H,Kessing B,Alvirez E,Castillo M,Morales H,Argueta V,Rosingh A,van Aerde-van Nunen FJHB,Lopez

更新日期：2018-05-15 00:00:00

abstract：BACKGROUND:DEK is a transcription factor involved in stabilization of heterochromatin and cruciform structures. It plays an important role in development and progression of different types of cancer. This study aims to analyze the role of DEK in metastatic colorectal cancer. METHODS:Baseline DEK expression was firstly...

journal_title：BMC cancer

authors： Martinez-Useros J,Rodriguez-Remirez M,Borrero-Palacios A,Moreno I,Cebrian A,Gomez del Pulgar T,del Puerto-Nevado L,Vega-Bravo R,Puime-Otin A,Perez N,Zazo S,Senin C,Fernandez-Aceñero MJ,Soengas MS,Rojo F,Garcia-Foncillas J

更新日期：2014-12-16 00:00:00

abstract：BACKGROUND:Long non-coding RNAs have been shown to have critical regulatory roles in cancer biology. However, the contributions of lncRNAs to gastric cancer remain largely unknown. METHODS:The differential expression of lncRNAs in gastric cancer and paired non-cancerous tissues were identified by microarray and valida...

journal_title：BMC cancer

authors： Han Y,Ye J,Wu D,Wu P,Chen Z,Chen J,Gao S,Huang J

更新日期：2014-12-11 00:00:00

abstract：BACKGROUND:Desmoid tumour is a benign, non metastasising neoplasm characterised by an elevated deposition of organic macromolecules in the extracellular matrix (ECM). The matrix metalloproteinases (MMPs) are a family of zinc-dependent proteinases involved in the degradation of ECM macromolecules. The MMPs and their nat...

journal_title：BMC cancer

authors： Balducci C,Lilli C,Stabellini G,Marinucci L,Giustozzi G,Becchetti A,Cagini L,Locci P

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Immune checkpoint inhibitors (ICIs) were approved to have a significant antitumor activity in various tumor types. In practice, some patients do not seem to benefit from ICIs but rather to have accelerating disease. The aim of this study was to evaluate hyperprogression in patients with malignant tumors of d...

journal_title：BMC cancer

authors： Ji Z,Peng Z,Gong J,Zhang X,Li J,Lu M,Lu Z,Shen L

更新日期：2019-07-17 00:00:00

abstract：BACKGROUND:Cognitive therapy has been shown to reduce fear of cancer recurrence (FCR), mainly in breast cancer survivors. The accessibility of cognitive behavioural interventions could be further improved by Internet delivery, but self-guided interventions have shown limited efficacy. The aim of this study is to test t...

journal_title：BMC cancer

authors： Lyhne JD,Smith A'B,Frostholm L,Fink P,Jensen LH

更新日期：2020-03-16 00:00:00

abstract：BACKGROUND:The EphB4 receptor tyrosine kinase has been reported as increased in tumours originating from several different tissues and its expression in a prostate cancer xenograft model has been reported. METHODS:RT-PCR, western blotting and immunohistochemical techniques were used to examine EphB4 expression and pro...

journal_title：BMC cancer

authors： Lee YC,Perren JR,Douglas EL,Raynor MP,Bartley MA,Bardy PG,Stephenson SA

更新日期：2005-09-20 00:00:00

abstract：BACKGROUND:Colorectal peritoneal carcinomatosis (CRPC) is a common form of systemic metastasis of intra-abdominal cancers. Intraperitoneal chemotherapy is a preferable option for colorectal cancer. Here we reported that a new system, 5-FU-loaded hydrogel system, can improve the therapeutic effects of intraperitoneal ch...

journal_title：BMC cancer

authors： Wang Y,Gong C,Yang L,Wu Q,Shi S,Shi H,Qian Z,Wei Y

更新日期：2010-08-02 00:00:00

abstract：BACKGROUND:Improving the coordination of cancer care is a priority area for service improvement. However, quality improvement initiatives are hindered by the lack of accurate and reliable measures of this aspect of cancer care. This study was conducted to develop a questionnaire to measures patients' experience of canc...

journal_title：BMC cancer

authors： Young JM,Walsh J,Butow PN,Solomon MJ,Shaw J

更新日期：2011-07-15 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via the original article. ...

journal_title：BMC cancer

authors： Al-Khayal K,Vaali-Mohammed MA,Elwatidy M,Traiki TB,Al-Obeed O,Azam M,Khan Z,Abdulla M,Ahmad R

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:With the availability of effective anti-EGFR therapies for various solid malignancies, such as non-cell small lung cancer, colorectal cancer and squamous cell carcinoma of the head and neck, the knowledge of EGFR and K-RAS status becomes clinically important. The aim of this study was to analyse EGFR express...

journal_title：BMC cancer

authors： Van Damme N,Deron P,Van Roy N,Demetter P,Bols A,Van Dorpe J,Baert F,Van Laethem JL,Speleman F,Pauwels P,Peeters M

更新日期：2010-05-11 00:00:00

abstract：BACKGROUND:As aging is the most significant risk factor for cancer development, long-term prostate cancer (PCa) survivors have an evident risk of developing subsequent primary cancers (SPCs). Radiotherapy itself is an additional risk factor for cancer development and the SPCs appearing beyond 5 years after radiotherapy...

journal_title：BMC cancer

authors： Vuolukka K,Auvinen P,Palmgren JE,Aaltomaa S,Kataja V

更新日期：2020-05-20 00:00:00

abstract：BACKGROUND:We evaluated if the survival benefit of adding rituximab to standard chemotherapy for non-Hodgkin lymphoma (NHL) observed in clinical trials has been experienced by an Australian NHL patient population. METHODS:NHL cases diagnosed in 1985-2004 in New South Wales (NSW) were followed-up to the end of 2004. Ri...

journal_title：BMC cancer

authors： Yu XQ,Chen WH,O'Connell DL

更新日期：2010-05-24 00:00:00

abstract：BACKGROUND:The discovery of a solitary pulmonary nodule (SPN) on a chest imaging exam is of major clinical concern. However, the incidence rates of SPNs in a general population have not been estimated. The objective of this study was to provide incidence estimates of SPNs in a general population in 5 northeastern regio...

journal_title：BMC cancer

authors： Marrer É,Jolly D,Arveux P,Lejeune C,Woronoff-Lemsi MC,Jégu J,Guillemin F,Velten M

更新日期：2017-01-11 00:00:00

abstract：BACKGROUND:SPINK4 is known as a gastrointestinal peptide in the gastrointestinal tract and is abundantly expressed in human goblet cells. The clinical significance of SPINK4 in colorectal cancer (CRC) is largely unknown. METHODS:We retrieved the expression data of 1168 CRC patients from 3 Gene Expression Omnibus (GEO)...

journal_title：BMC cancer

authors： Wang X,Yu Q,Ghareeb WM,Zhang Y,Lu X,Huang Y,Huang S,Sun Y,Lin J,Liu J,Chi P

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:Excision repair cross-complementing group 2 (ERCC2) plays important roles in the repair of DNA damage and adducts. Single nucleotide polymorphisms (SNPs) of ERCC2 gene are suspected to influence the risks of oral cancer. We performed a meta-analysis to systematically summarize the possible association of ERC...

journal_title：BMC cancer

authors： Zhang E,Cui Z,Xu Z,Duan W,Huang S,Tan X,Yin Z,Sun C,Lu L

更新日期：2013-12-12 00:00:00

abstract：BACKGROUND:Breast carcinomas with neuroendocrine features (NEBC) are a very rare entity of mammary neoplasms, WHO classification of which has recently been revised. There are very limited data available about the clinical behaviour and treatment options of NEBC. METHODS:We collected retrospectively patients with NEBC ...

journal_title：BMC cancer

authors： Roininen N,Takala S,Haapasaari KM,Jukkola-Vuorinen A,Mattson J,Heikkilä P,Karihtala P

更新日期：2017-01-24 00:00:00

abstract：BACKGROUND:To determine, in a meta-analysis, the diagnostic performance of quantitative diffusion-weighted (DW) MR imaging in patients with breast lesions. METHODS:English and Chinese studies published prior to June 2009 to assess the diagnostic performance of quantitative DWI in patients with breast lesions were revi...

journal_title：BMC cancer

authors： Chen X,Li WL,Zhang YL,Wu Q,Guo YM,Bai ZL

更新日期：2010-12-29 00:00:00

abstract：BACKGROUND:Pancreatic adenocarcinoma is one of the most dreaded cancers with very low survival rate and poor prognosis to the existing frontline chemotherapeutic drugs. Gene therapy in combination with a cytotoxic agent could be a promising approach to circumvent the limitations of previously attempted therapeutic inte...

journal_title：BMC cancer

authors： Xu J,Singh A,Amiji MM

更新日期：2014-02-08 00:00:00

abstract：:It has been highlighted that the original manuscript [1] contains a typesetting error in the surname of Jesson Butcon. This was incorrectly captured as Jessica Butcon in the original manuscript which has since been updated. ...

journal_title：BMC cancer

authors： Chan RJ,Yates P,Li Q,Komatsu H,Lopez V,Thandar M,Chacko ST,So WKW,Pongthavornkamol K,Yi M,Pittayapan P,Butcon J,Wyld D,Molassiotis A,STEP study collaborators.

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The effect of current therapies in improving the survival of lung cancer patients remains far from satisfactory. It is consequently desirable to find more appropriate therapeutic opportunities based on informed insights. A molecular pharmacological analysis was undertaken to design an improved chemotherapeut...

journal_title：BMC cancer

authors： Gemma A,Li C,Sugiyama Y,Matsuda K,Seike Y,Kosaihira S,Minegishi Y,Noro R,Nara M,Seike M,Yoshimura A,Shionoya A,Kawakami A,Ogawa N,Uesaka H,Kudoh S

更新日期：2006-06-30 00:00:00

abstract：BACKGROUND:The impact of local tumor ablative therapy in oligometastasized prostate cancer (PC) is still under debate. To gain data for this approach, we evaluated oligometastasized PC patients receiving stereotactic body radiotherapy (SBRT) to bone metastases. METHODS:In this retrospective study, 15 oligometastasized...

journal_title：BMC cancer

authors： Habl G,Straube C,Schiller K,Duma MN,Oechsner M,Kessel KA,Eiber M,Schwaiger M,Kübler H,Gschwend JE,Combs SE

更新日期：2017-05-22 00:00:00

abstract：OBJECTIVE:C-reactive protein (CRP) is considered a useful serum marker for patients with RCC. However, its clinical utility in advanced metastatic renal cell carcinoma (AM-RCC), particularly in deciding whether to perform nephrectomy at the onset, is not well studied. PATIENTS AND METHODS:We retrospectively evaluated ...

journal_title：BMC cancer

authors： Ito H,Shioi K,Murakami T,Takizawa A,Sano F,Kawahara T,Mizuno N,Makiyama K,Nakaigawa N,Kishida T,Miura T,Kubota Y,Yao M

更新日期：2012-08-02 00:00:00

abstract：BACKGROUND:Recent large trials have shown the survival benefits of 10-year use of tamoxifen by reducing late recurrence compared with 5-year therapy in estrogen receptor(ER)-positive breast cancer. We tried to identify clinical factors associated with the late recurrence. METHODS:We reviewed our database of ER-positiv...

journal_title：BMC cancer

authors： Lee ES,Han W,Kim MK,Kim J,Yoo TK,Lee MH,Lee KH,Kim TY,Moon HG,Im SA,Noh DY,Lee ES

更新日期：2016-07-07 00:00:00

abstract：BACKGROUND:TGFβ signaling has typically been associated with suppression of tumor initiation while the role it plays in metastasis is generally associated with progression of malignancy. However, we present evidence here for an anti-metastatic role of TGFβ signaling. METHODS:To test the importance of TGFβ signaling to...

journal_title：BMC cancer

authors： Simms NA,Rajput A,Sharratt EA,Ongchin M,Teggart CA,Wang J,Brattain MG

更新日期：2012-06-06 00:00:00

abstract：BACKGROUND:The transcription factor nuclear factor erythroid 2-related factor 2 (NFE2L2; previously known as NRF2) is a crucial regulator of the intracellular antioxidant response. It controls the expression of genes involved in the detoxification and elimination of reactive oxidants and electrophilic agents. The role ...

journal_title：BMC cancer

authors： Wolf B,Goebel G,Hackl H,Fiegl H

更新日期：2016-10-22 00:00:00

abstract：:ABSTRACT: BACKGROUND: The aim of this study was to assess the extent of knowledge of primary health care (PHC) patients about colorectal cancer (CRC), their attitudes toward population-based screening for this disease and gender differences in these respects. METHODS: A questionnaire-based survey of PHC patients in t...

journal_title：BMC cancer

authors： Ramos M,Llagostera M,Esteva M,Cabeza E,Cantero X,Segarra M,Martín-Rabadán M,Artigues G,Torrent M,Taltavull JM,Vanrell JM,Marzo M,Llobera J

更新日期：2011-09-25 00:00:00

abstract：BACKGROUND:Bladder cancer is the ninth most common type of cancer worldwide. In the past, radical cystectomy via open surgery has been considered the gold-standard treatment for muscle invasive bladder cancer. However, in recent years there has been a progressive increase in the use of robot-assisted laparoscopic radic...

journal_title：BMC cancer

authors： Porreca A,Palmer K,Artibani W,Antonelli A,Bianchi L,Brunocilla E,Bocciardi AM,Brausi M,Busetto GM,Carini M,Carrieri G,Celia A,Cindolo L,Cochetti G,Colombo R,De Berardinis E,De Cobelli O,Di Maida F,Ercolino A,Gaboard

更新日期：2021-01-11 00:00:00

abstract：BACKGROUND:The 'common variant, common disease' model predicts that a significant component of hereditary breast cancer unexplained by pathogenic variants in moderate or high-penetrance genes is due to the cumulative effect of common risk variants in DNA (polygenic risk). Assessing a woman's breast cancer risk by testi...

journal_title：BMC cancer

authors： Yanes T,Meiser B,Young MA,Kaur R,Mitchell G,Barlow-Stewart K,Roscioli T,Halliday J,James P

更新日期：2017-07-18 00:00:00