当前位置： SCI文献检索 > DISEASES OF THE ESOPHAGUS期刊下所有文献 > Outcomes of definitive chemoradiation in patients with esophageal cancer.

Outcomes of definitive chemoradiation in patients with esophageal cancer.

Abstract：

:The incidence of esophageal cancer has risen dramatically in the Western world. Although surgical resection of esophageal tumors is considered the cornerstone of curative approaches in localized esophageal cancer, approximately 40% of patients who undergo chemoradiation followed by surgery will experience a recurrence. Additionally, surgical resection is not a viable option for many patients with locally advanced unresectable disease, poor general condition or whose condition deteriorated following chemoradiation. Several investigators have, therefore, attempted to evaluate the outcomes of definitive chemoradiation in patients with localized or locally advanced esophageal cancer. The outcomes of concurrent chemoradiation remain a matter of debate given the heterogenous study design and treatment regimens used in recent trials. Understanding the clinical benefit of chemoradiation is essential prior to recommending it as an alternative to surgery. In our review, we present the most recent studies evaluating the role of chemoradiation to better define the clinical outcomes of patients with special attention to overall survival.

journal_name

Dis Esophagus

journal_title

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors

Mikhail S,Wei L,Salem ME,Bekaii-Saab T

doi

10.1111/dote.12506

subject

Has Abstract

pub_date

2017-02-01 00:00:00

pages

1-7

issue

2

eissn

1120-8694

issn

1442-2050

journal_volume

30

pub_type

杂志文章,评审

相关文献

DISEASES OF THE ESOPHAGUS文献大全
  • The utility of endoscopic screening for patients with esophageal or head and neck cancer.

    abstract：:In a series of 378 patients with esophageal carcinoma, 43 patients with head and neck carcinoma were divided into two groups: 30 patients without symptoms whose esophageal or head and neck second primary carcinomas were incidentally detected by an endoscopic examination for the second carcinoma (group 1) and 13 patien...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1046/j.1442-2050.1999.00045.x

    authors： Murakami S,Hashimoto T,Noguchi T,Hazamada S,Uchida Y,Suzuki M,Yanagisawa S

    更新日期：1999-01-01 00:00:00

  • Comparative retrospective study on the use of plastic prostheses and self-expanding metal stents in the palliative treatment of malignant strictures of the esophagus and cardia.

    abstract：:Palliative treatment of malignant strictures of the esophagus and cardia is usually carried out by the endoscopic placement of a prosthesis. The aim of this retrospective study was to evaluate short- and long-term outcomes of the use of expandable stents, compared with conventional plastic prostheses. One hundred and ...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1046/j.1442-2050.2003.00308.x

    authors： Mosca F,Consoli A,Stracqualursi A,Persi A,Portale TR

    更新日期：2003-01-01 00:00:00

  • Results after laparoscopic Heller-Dor operation for esophageal achalasia in 100 consecutive patients.

    abstract：:The laparoscopic Heller-Dor operation has been the procedure of choice for the treatment of achalasia. However, because the incidence of achalasia is low, reports on the outcome of surgical treatment for achalasia are limited. In this study, the therapeutic results after laparoscopic Heller-Dor operation for achalasia...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2008.00891.x

    authors： Tsuboi K,Omura N,Yano F,Kashiwagi H,Yanaga K

    更新日期：2009-01-01 00:00:00

  • Predictive biomarkers for Barrett's esophagus: so near and yet so far.

    abstract：:Barrett's esophagus (BE) is the strongest risk factor for the development of esophageal adenocarcinoma. However, the risk of cancer progression is difficult to ascertain in individuals, as a significant number of patients with BE do not necessarily progress to esophageal adenocarcinoma. There are several issues with t...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章,评审

    doi：10.1111/dote.12015

    authors： Timmer MR,Sun G,Gorospe EC,Leggett CL,Lutzke L,Krishnadath KK,Wang KK

    更新日期：2013-08-01 00:00:00

  • Intraoperative recurrent laryngeal nerve monitoring: a useful method for patients with esophageal cancer.

    abstract：:It is well accepted that recurrent laryngeal nerve paralysis is a severe complication of esophagectomy or lymphadenectomy performed adjacent to the recurrent laryngeal nerves. Herein, determination of the effectiveness of implementing continuous recurrent laryngeal nerve monitoring to reduce the incidence of recurrent...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2012.01414.x

    authors： Zhong D,Zhou Y,Li Y,Wang Y,Zhou W,Cheng Q,Chen L,Zhao J,Li X,Yan X

    更新日期：2014-07-01 00:00:00

  • Prognostic relevance of serial endoscopic ultrasound after chemoradiation in esophageal cancer.

    abstract：:The objective of this study is the feasibility of sequential endoscopic and endosonographic measurement of locoregional tumor load for the prediction of tumor recurrence in patients after neoadjuvant or definitive chemoradiotherapy, treated in curative intent for locally advanced esophageal carcinoma. In 67 patients w...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1093/dote/dox065

    authors： Bohle W,Kasper M,Zoller WG

    更新日期：2017-10-01 00:00:00

  • Achalasia: physiology and etiopathogenesis.

    abstract：:Achalasia is a disorder of esophageal motility that has been well documented for over 300 years. Despite this, the initiating factor or factors and the underlying mechanisms leading to the characteristic features of achalasia, the absence of distal esophageal peristalsis and abnormal lower esophageal sphincter relaxat...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章,评审

    doi：10.1111/j.1442-2050.2006.00569.x

    authors： Kraichely RE,Farrugia G

    更新日期：2006-01-01 00:00:00

  • Validation of a biomarker panel in Barrett's esophagus to predict progression to esophageal adenocarcinoma.

    abstract：:In a prior study, baseline mutational load (ML) predicted progression to high-grade dysplasia (HGD) or esophageal adenocarcinoma (EAC) in Barrett's esophagus (BE) with an area under the curve (AUC) of 0.95. We aimed to validate the test characteristics of this predictive biomarker panel using crude DNA lysates in a la...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1093/dote/doy026

    authors： Eluri S,Klaver E,Duits LC,Jackson SA,Bergman JJ,Shaheen NJ

    更新日期：2018-11-01 00:00:00

  • FA01.02: THE EFFECT OF POSTOPERATIVE COMPLICATIONS AFTER MIE ON LONG-TERM SURVIVAL: A RETROSPECTIVE, MULTI-CENTER COHORT STUDY.

    abstract：Background:Esophagectomy has a high incidence of postoperative morbidity. Complications lead to a decreased short-term survival, however the influence of those complications on long-term survival is still unclear. Most of the performed studies are small, single center cohort series with inconclusive or conflicting resu...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章,多中心研究

    doi：10.1093/dote/doy089.FA01.02

    authors： Fransen L,Berkelmans G,Asti E,Van Berge Henegouwen M,Berlth F,Bonavina L,Brown A,Bruns C,Gisbertz S,Grimminger P,Gutschow C,Hölscher A,Kauppi J,Lagarde SM,Mercer S,Moons J,Nafteux P,Nilsson M,Palazzo F,Pattyn P,Ph

    更新日期：2018-09-01 00:00:00

  • Management of patients with giant paraesophageal hernia.

    abstract：:Paraesophageal herniation can cause massive bleeding, strangulation or perforation. This study reviews the experience with 24 patients (74.6 years, range 63-89 years, 20 males, 4 females) with a total or near-total intrathoracic stomach, managed at the Royal Lancaster Infirmary. All patients were symptomatic with 3/24...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1093/dote/11.3.177

    authors： Leese T,Perdikis G

    更新日期：1998-07-01 00:00:00

  • Trimodality therapy and definitive chemoradiotherapy for esophageal cancer: a single-center experience and review of the literature.

    abstract：:In the UK, the standard of care for esophageal cancer has generally combined surgery with neoadjuvant chemotherapy, with definitive chemoradiotherapy (dCRT) being reserved for certain subgroups. Chemoradiotherapy followed by surgery (trimodality therapy) has not been widely adopted. The outcomes of patients undergoing...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章,评审

    doi：10.1111/dote.12242

    authors： Hategan M,Cook N,Prewett S,Hindmarsh A,Qian W,Gilligan D

    更新日期：2015-10-01 00:00:00

  • Evaluation of clinical significance of 18F-fluorodeoxyglucose positron emission tomography in superficial squamous cell carcinomas of the thoracic esophagus.

    abstract：:(18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is used for pre-treatment staging and evaluation of response to pre-operative therapy in advanced thoracic esophageal cancers. To evaluate the clinical significance of PET diagnosis of superficial thoracic esophageal cancers, FDG-PET was conducted preop...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2007.00743.x

    authors： Miyata H,Doki Y,Yasuda T,Yamasaki M,Higuchi I,Makari Y,Matsuyama J,Hirao T,Takiguchi S,Fujiwara Y,Monden M

    更新日期：2008-01-01 00:00:00

  • Outcome and risk factors assessment for adverse events in advanced esophageal cancer patients after self-expanding metal stents placement.

    abstract：:Self-expanding metal stents (SEMS) are the treatment of choice for advanced esophageal cancers. Literature is scarce on risk factors predictors for adverse events after SEMS placement. Assess risk factors for adverse events after SEMS placement in advanced esophageal cancer and evaluate survival after SEMS placement. ...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/dote.12467

    authors： Rodrigues-Pinto E,Pereira P,Coelho R,Andrade P,Ribeiro A,Lopes S,Moutinho-Ribeiro P,Macedo G

    更新日期：2017-02-01 00:00:00

  • Colon interposition in the treatment of esophageal caustic strictures: 40 years of experience.

    abstract：:The objective of this article was to analyze 40 years of experience of colon interposition in the surgical treatment of caustic esophageal strictures from the standpoints of our long-term personal experience. Colon interposition has proved to be the most suitable type of reconstruction for esophageal corrosive strictu...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2007.00694.x

    authors： Knezević JD,Radovanović NS,Simić AP,Kotarac MM,Skrobić OM,Konstantinović VD,Pesko PM

    更新日期：2007-01-01 00:00:00

  • Impedance nadir values correlate with barium bolus amount.

    abstract：:We examined the value of impedance monitoring in measuring bolus volume compared with videoesophagram. Eighty consecutive subjects were studied with simultaneous impedance-manometry-videoesophagram. A catheter with both an impedance electrode pair and a pressure transducer at four sites (5, 10, 15, 20 cm above lower e...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2011.01302.x

    authors： Imam H,Marrero F,Shay S

    更新日期：2012-09-01 00:00:00

  • Novel association of achalasia with hereditary sensory and motor neuropathy with sensorineural deafness.

    abstract：:Achalasia is a primary esophageal motility disorder. Unlike diffuse esophageal spasm, it has not previously been described in association with hereditary sensory and motor neuropathy (HSMN). An 18-year-old-male with HSMN with sensorineural deafness presented with a 2-day history of dysphagia to solids and liquids. Ach...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type：

    doi：10.1111/dote.12111

    authors： Asthana AK,Lubel JS,Kohn GP

    更新日期：2016-08-01 00:00:00

  • Reduced toxicity with three-dimensional conformal radiotherapy or intensity-modulated radiotherapy compared with conventional two-dimensional radiotherapy for esophageal squamous cell carcinoma: a secondary analysis of data from four prospective clinical

    abstract：:We conducted a retrospective analysis to assess the toxicity and long-term survival of esophageal squamous cell carcinoma patients treated with three-dimensional conformal radiotherapy (3DCRT) or intensity-modulated radiotherapy (IMRT) versus conventional two-dimensional radiotherapy (2DRT). All data in the present st...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/dote.12435

    authors： Deng JY,Wang C,Shi XH,Jiang GL,Wang Y,Liu Y,Zhao KL

    更新日期：2016-11-01 00:00:00

  • Coexistence of esophageal granular cell tumor and squamous cell carcinoma: a case report.

    abstract：:Granular cell tumors (GCTs) are relatively uncommon, usually benign and solitary neoplasms. Until now, about 200 cases of esophageal GCTs have been reported in the literature. We present a rare case of synchronous occurrence of esophageal GCT and moderately differentiated squamous cell carcinoma in a 40-year-old white...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章,评审

    doi：10.1046/j.1442-2050.2002.00232.x

    authors： Szumilo J,Dabrowski A,Skomra D,Chibowski D

    更新日期：2002-01-01 00:00:00

  • Thoracic esophageal perforation: one surgeon's experience.

    abstract：:Recognition of the importance of early diagnosis and aggressive, definitive surgical intervention has brought about a dramatic decline in mortality related to distal esophageal perforation. In the following retrospective analysis, we have examined all cases of thoracic esophageal perforations diagnosed, consulted, and...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2006.00533.x

    authors： Kiernan PD,Sheridan MJ,Hettrick V,Vaughan B,Graling P

    更新日期：2006-01-01 00:00:00

  • Inverse correlation between NKG2D expression on CD8+ T cells and the frequency of CD4+CD25+ regulatory T cells in patients with esophageal cancer.

    abstract：:Although malignant diseases are known to be associated with immune suppression, detailed mechanisms of this phenomenon are still unknown. NKG2D is an activating cell surface receptor expressed by natural killer (NK) cells and CD8+ T cells, and it has been reported that NKG2D engagement is extremely important for T cel...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2008.00855.x

    authors： Osaki T,Saito H,Fukumoto Y,Yamada Y,Fukuda K,Tatebe S,Tsujitani S,Ikeguchi M

    更新日期：2009-01-01 00:00:00

  • Long-term weight development after esophagectomy for cancer-comparison between open Ivor-Lewis and minimally invasive surgical approaches.

    abstract：:Esophagectomy is an extensive procedure with severe postoperative effects. It can be assumed that the greater the trauma, the longer the nutritional recovery. This retrospective observational single-center cohort study compared weight development after esophagectomy with open and minimally invasive techniques. Three g...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1093/dote/doy075

    authors： Ericson J,Lundell L,Klevebro F,Kamiya S,Nilsson M,Rouvelas I

    更新日期：2019-04-01 00:00:00

  • Circumferential and axial distribution of esophageal mucosal damage in reflux disease.

    abstract：:The aim of this study was to evaluate the axial and radial distribution of histological markers including hyperplasia of the basal cell layer, elongation of the papillae and dilatation of the intercellular spaces of the squamous epithelium in patients with nonerosive reflux disease compared to controls and to relate t...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2007.00678.x

    authors： Edebo A,Vieth M,Tam W,Bruno M,van Berkel AM,Stolte M,Schoeman M,Tytgat G,Dent J,Lundell L

    更新日期：2007-01-01 00:00:00

  • Novel stent in the palliation of malignant esophageal strictures: a retrospective study.

    abstract：:The placement of metal stents is often used as a palliative treatment for malignant esophageal stenosis. We designed a novel stent that has been used clinically since 2011, and we therefore performed a retrospective study to compare the therapeutic effects of this novel metal stent to a conventional partially covered ...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/dote.12446

    authors： Chen H,Ni Z,Jing D,He L,Qiao L,Liu L,Wei X,Jiang M,Tang S,Xu H

    更新日期：2017-02-01 00:00:00

  • Laparoscopic inversion esophagectomy: simplifying a daunting operation.

    abstract：:Minimally invasive esophageal resection is a technically demanding procedure that may reduce patient morbidity and improve convalescence when compared with the open approach. Despite these proposed advantages, the minimally invasive approach has not been widely embraced and is routinely performed in only a few special...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2004.00383.x

    authors： Jobe BA,Reavis KM,Davis JJ,Hunter JG

    更新日期：2004-01-01 00:00:00

  • Two novel polymorphisms in PLCE1 are associated with the susceptibility to esophageal squamous cell carcinoma in Chinese population.

    abstract：:Esophageal cancer is the sixth leading cause of cancer-associated death worldwide. Phospholipase C epsilon 1 (PLCE1) gene was found to be associated with the risk of esophageal squamous cell carcinoma (ESCC) by three large-scale genome-wide association studies (GWAS) in Chinese populations. To evaluate the association...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/dote.12463

    authors： Qu Y,Zhang S,Cui L,Wang K,Song C,Wang P,Zhang J,Dai L

    更新日期：2017-01-01 00:00:00

  • Expression of p21(Waf1/Cip1) predicts response and survival of esophageal cancer patients treated by chemoradiotherapy.

    abstract：:Chemoradiotherapy is a multimodal therapy routinely used as a primary treatment for advanced esophageal cancer. However, it is beneficial only to patients who respond. To identify pretreatment markers predicting response and survival, we examined the expression of cell cycle regulatory molecules, p53, p21(Waf1/Cip1) c...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2004.00433.x

    authors： Nakamura T,Hayashi K,Ota M,Ide H,Takasaki K,Mitsuhashi M

    更新日期：2004-01-01 00:00:00

  • Comparison of the effect of a cornstarch thickened formula and strengthened regular formula on regurgitation, gastric emptying and weight gain in infantile regurgitation.

    abstract：:The purpose of this study was to evaluate the efficacy of a specially selected cornstarch-supplemented formula on clinical symptoms, gastric emptying and weight gain in infants with regurgitation. We performed a prospective randomised trial evaluating the therapeutic efficacy of two different formula feedings (cornsta...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/j.1442-2050.2007.00662.x

    authors： Chao HC,Vandenplas Y

    更新日期：2007-01-01 00:00:00

  • Differential expression of TCEAL1 in esophageal cancers by custom cDNA microarray analysis.

    abstract：:To find new genes involved in esophageal squamous cell carcinogenesis, we constructed custom cDNA arrays and used the arrays to compare gene expression profiles of 12 matched normal and malignant esophageal samples including seven superficial cancer tissues. The arrays represented nearly 4000 genes, including 1728 tha...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2005.00432.x

    authors： Makino H,Tajiri T,Miyashita M,Sasajima K,Anbazhagan R,Johnston J,Gabrielson E

    更新日期：2005-01-01 00:00:00

  • Outcomes of induction chemotherapy followed by chemoradiation using intensity-modulated radiation therapy for esophageal adenocarcinoma.

    abstract：:This study looks at toxicity and survival data when chemoradiation (CRT) is delivered using intensity-modulated radiation therapy (IMRT) after induction chemotherapy. Forty-one patients with esophageal adenocarcinoma treated with IMRT from March 2007 to May 2009 at Memorial Sloan-Kettering Cancer Center were analyzed....

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/dote.12082

    authors： Gerber N,Ilson DH,Wu AJ,Janjigian YY,Kelsen DP,Zheng J,Zhang Z,Bains MS,Rizk N,Rusch VW,Goodman KA

    更新日期：2014-04-01 00:00:00

  • Voluntary and controlled weight loss can reduce symptoms and proton pump inhibitor use and dosage in patients with gastroesophageal reflux disease: a comparative study.

    abstract：:A wide variety of pieces of evidence has suggested that obesity is associated with a significant increase in the risk for gastroesophageal reflux disease (GERD) symptoms and its complications. The aim of this study was to evaluate the effect of weight loss on reflux symptoms in overweight/obese patients with proven GE...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/dote.12319

    authors： de Bortoli N,Guidi G,Martinucci I,Savarino E,Imam H,Bertani L,Russo S,Franchi R,Macchia L,Furnari M,Ceccarelli L,Savarino V,Marchi S

    更新日期：2016-02-01 00:00:00