The role of inferior petrosal sinus sampling in the diagnostic localization of Cushing's disease.

Abstract:

:Cushing's syndrome can present a complex problem of differential diagnosis. Of cases in which hypercortisolemia results from an adrenocorticotropic hormone (ACTH)-dependent process, approximately 80% are due to a pituitary adenoma (Cushing's disease [CD]), 10% are due to adrenal lesions, and the remaining 10% are secondary to ectopic ACTH secretion. For patients with CD, surgical removal of the pituitary adenoma is the treatment of choice. Thus, localization of the source of ACTH secretion is critical in guiding timely treatment decisions. Inferior petrosal sinus sampling (IPSS) is considered to be the gold standard for confirming the origin of ACTH secretion in patients with Cushing's syndrome. The authors present an overview of IPSS--both the technique and its interpretation--as well as a summary of recent studies. A number of other techniques are discussed including sampling from the cavernous sinus, the jugular vein, and multiple sites to aid the diagnosis and lateralization of ACTH-producing pituitary adenomas. Management is best undertaken by a comprehensive multidisciplinary team taking into account the results of all the biochemical and imaging studies available, to provide the best advice in patient treatment decisions.

journal_name

Neurosurg Focus

journal_title

Neurosurgical focus

authors

Lad SP,Patil CG,Laws ER Jr,Katznelson L

doi

10.3171/foc.2007.23.3.3

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

E2

issue

3

issn

1092-0684

journal_volume

23

pub_type

杂志文章,评审
  • The impact of African-trained neurosurgeons on sub-Saharan Africa.

    abstract:OBJECTIVE:Sub-Saharan Africa (SSA) represents 17% of the world's land, 14% of the population, and 1% of the gross domestic product. Previous reports have indicated that 81/500 African neurosurgeons (16.2%) worked in SSA-i.e., 1 neurosurgeon per 6 million inhabitants. Over the past decades, efforts have been made to imp...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2019.12.FOCUS19853

    authors: Karekezi C,El Khamlichi A,El Ouahabi A,El Abbadi N,Ahokpossi SA,Ahanogbe KMH,Berete I,Bouya SM,Coulibaly O,Dao I,Djoubairou BO,Doleagbenou AAK,Egu KP,Ekouele Mbaki HB,Kinata-Bambino SB,Habibou LM,Mousse AN,Ngamasata T,

    更新日期:2020-03-01 00:00:00

  • Historical perspectives on the diagnosis and treatment of trigeminal neuralgia.

    abstract::Since the earliest recorded history of medicine, physicians have been challenged by the difficulty in relieving the great pain experienced by individuals suffering from trigeminal neuralgia (TN). The nature of the pain and the events that incite it have been well described, but effective treatments with acceptable lev...

    journal_title:Neurosurgical focus

    pub_type: 历史文章,杂志文章

    doi:10.3171/foc.2005.18.5.5

    authors: Cole CD,Liu JK,Apfelbaum RI

    更新日期:2005-05-15 00:00:00

  • Transcirculation Pipeline embolization device deployment: a rescue technique.

    abstract::The Pipeline embolization device (PED) has become a very important tool in the treatment of nonruptured cerebral aneurysms. However, a patient's difficult anatomy or vascular stenosis may affect the device delivery. The purpose of this article was to describe an alternate technique for PED deployment when ipsilateral ...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2017.2.FOCUS16485

    authors: Valle-Giler EP,Atallah E,Tjoumakaris S,Rosenwasser RH,Jabbour P

    更新日期:2017-06-01 00:00:00

  • Decision making for patients with multiple brain metastases: radiosurgery, radiotherapy, or resection?

    abstract:OBJECT:Multiple brain metastases are a common health problem, frequently found in patients with cancer. The prognosis, even after treatment with whole-brain radiation therapy (WBRT), is poor, with an average expected survival time of less than 6 months. Investigators at numerous centers have evaluated the role of stere...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,随机对照试验

    doi:10.3171/foc.2000.9.2.5

    authors: Kondziolka D,Patel A,Lunsford LD,Flickinger JC

    更新日期:2000-08-15 00:00:00

  • The strokes that killed Churchill, Roosevelt, and Stalin.

    abstract::From February 4 to 11, 1945, President Franklin D. Roosevelt of the United States, Soviet Union Premier Joseph Stalin, and British Prime Minister Winston Churchill met near Yalta in Crimea to discuss how post-World War II (WWII) Europe should be organized. Within 2 decades of this conference, all 3 men had died. Presi...

    journal_title:Neurosurgical focus

    pub_type: 传,历史文章,杂志文章

    doi:10.3171/2016.4.FOCUS1575

    authors: Ali R,Connolly ID,Li A,Choudhri OA,Pendharkar AV,Steinberg GK

    更新日期:2016-07-01 00:00:00

  • Ultrasonographic guidance for spinal extracranial radiosurgery: technique and application for metastatic spinal lesions.

    abstract:OBJECT:The relatively stationary anatomy of the intracranial compartment has allowed the development of stereotactic radiosurgery as an effective treatment option for many intracranial lesions. Difficulty in accurately tracking extracranial targets has limited its development in the treatment of these lesions. The abil...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/foc.2001.11.6.9

    authors: Ryken TC,Meeks SL,Traynelis V,Haller J,Bouchet LG,Bova FJ,Pennington EC,Buatti JM

    更新日期:2001-12-15 00:00:00

  • Contralateral C-7 transfer: is direct repair really superior to grafting?

    abstract::It is not uncommon for a severe traumatic brachial plexus injury to involve all 5 roots, resulting in a flail upper limb. In such cases, surgical reconstruction is often palliative, providing only rudimentary function. Nerve transfers are the mainstay of reconstructive strategies due to the predominance of root avulsi...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2017.4.FOCUS1794

    authors: Bhatia A,Doshi P,Koul A,Shah V,Brown JM,Salama M

    更新日期:2017-07-01 00:00:00

  • Surgical approaches for resection of vestibular schwannomas: translabyrinthine, retrosigmoid, and middle fossa approaches.

    abstract::Surgical removal remains one of the key treatment modalities for vestibular schwannomas. A team approach between a neurotologist and a neurosurgeon offers the patient the expertise of both specialties and maximizes the chances for an optimal outcome. Vestibular schwannomas can typically be resected through 1 of 3 main...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/2012.6.FOCUS12190

    authors: Chamoun R,MacDonald J,Shelton C,Couldwell WT

    更新日期:2012-09-01 00:00:00

  • Endovascular strategies for carotid cavernous and intracerebral dural arteriovenous fistulas.

    abstract::Interventional neuroradiology is a less invasive modality than open neurosurgery for the treatment of a wide range of neurovascular disorders. Refinements in technique and improvements in the design of microcatheters, guide wires, and embolic materials have yielded superior clinical outcomes and provided an impetus to...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/foc.2003.15.4.7

    authors: Ng PP,Higashida RT,Cullen S,Malek R,Halbach VV,Dowd CF

    更新日期:2003-10-15 00:00:00

  • Stereotactic radiosurgery boost to the resection bed for oligometastatic brain disease: challenging the tradition of adjuvant whole-brain radiotherapy.

    abstract:OBJECT:Whole-brain radiation therapy (WBRT) has been the traditional approach to minimize the risk of intracranial recurrence following resection of brain metastases, despite its potential for late neurotoxicity. In 2007, the authors demonstrated an equivalent local recurrence rate to WBRT by using stereotactic radiosu...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2009.9.FOCUS09191

    authors: Karlovits BJ,Quigley MR,Karlovits SM,Miller L,Johnson M,Gayou O,Fuhrer R

    更新日期:2009-12-01 00:00:00

  • Predictors of outcome of subdural empyema in children.

    abstract:OBJECTIVE:The aim of this study was to report the etiology, clinical features, microbiology, surgical outcome, and predictors of outcome of spontaneous subdural empyema (SDE). METHODS:The authors conducted a retrospective study in a tertiary hospital. Children up to 18 years of age, with a diagnosis of SDE with infect...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2019.5.FOCUS19268

    authors: Konar S,Gohil D,Shukla D,Sadashiva N,Uppar A,Bhat DI,Srinivas D,Arimappamagan A,Devi BI

    更新日期:2019-08-01 00:00:00

  • Comparison of minimally invasive transspinous and open approaches for thoracolumbar intradural-extramedullary spinal tumors.

    abstract::OBJECT Spinal tumor resection has historically been performed via open approaches, although minimally invasive approaches have recently been found to be effective in small cohort series. The authors compare surgical characteristics and clinical outcomes of surgery in patients undergoing mini-open and open approaches f...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2015.5.FOCUS15187

    authors: Raygor KP,Than KD,Chou D,Mummaneni PV

    更新日期:2015-08-01 00:00:00

  • Influence of indocyanine green angiography on microsurgical treatment of spinal perimedullary arteriovenous fistulas.

    abstract:OBJECTIVE:The microvascular anatomy of spinal perimedullary arteriovenous fistulas (AVFs) is more complicated than that of dural AVFs, and occlusion rates of AVF after open microsurgery or endovascular embolization are lower in patients with perimedullary AVFs (29%-70%) than they are in those with dural AVF (97%-98%). ...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2015.12.FOCUS15574

    authors: Takai K,Kurita H,Hara T,Kawai K,Taniguchi M

    更新日期:2016-03-01 00:00:00

  • Surgical treatment of tumors involving the cervicothoracic junction.

    abstract:OBJECT:Tumors involving the cervicothoracic junction can have a high propensity for causing instability, with kyphosis and spinal cord compression resulting. Treatment with decompression only can lead to further instability and worsening neurological status. In this article, the authors review their surgical experience...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/foc.2003.15.5.3

    authors: Le H,Balabhadra R,Park J,Kim D

    更新日期:2003-11-15 00:00:00

  • Technical considerations in transforaminal endoscopic spine surgery at the thoracolumbar junction: report of 3 cases.

    abstract::OBJECTIVE In this study the authors describe the technical considerations and feasibility of transforaminal discectomy and foraminoplasty for the treatment of lumbar radiculopathy in patients who have herniated discs at the thoracolumbar junction. METHODS After institutional review board approval, charts from 3 consec...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2015.10.FOCUS15372

    authors: Telfeian AE,Jasper GP,Oyelese AA,Gokaslan ZL

    更新日期:2016-02-01 00:00:00

  • Microsurgical clip reconstruction techniques for aneurysms with significant calcified neck.

    abstract::A common surgical complication of clipping aneurysms with a calcified neck is the calcified atheroma compromising the parent arteries after clipping the neck. Clips can slip downward at the calcified neck or cause calcified atheroma encroaching the parent arteries. This video demonstrates a reconstructive clip techniq...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2015.7.FocusVid.14615

    authors: H Turkmani A,Day AL,Kim DH,Chen PR

    更新日期:2015-07-01 00:00:00

  • Pediatric sports-related traumatic brain injury in United States trauma centers.

    abstract::OBJECTIVE Traumatic brain injury (TBI) in children is a significant public health concern estimated to result in over 500,000 emergency department (ED) visits and more than 60,000 hospitalizations in the United States annually. Sports activities are one important mechanism leading to pediatric TBI. In this study, the ...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2016.1.FOCUS15612

    authors: Yue JK,Winkler EA,Burke JF,Chan AK,Dhall SS,Berger MS,Manley GT,Tarapore PE

    更新日期:2016-04-01 00:00:00

  • The health care burden of patients with epilepsy in the United States: an analysis of a nationwide database over 15 years.

    abstract:OBJECT:The aim of this study was to analyze the national health care burden of patients diagnosed with epilepsy in the US and to analyze any changes in the length of stay, mean charges, in-hospital deaths (mortality), and disposition at discharge. METHODS:A retrospective review of the Nationwide Inpatient Sample (NIS)...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2012.1.FOCUS11322

    authors: Vivas AC,Baaj AA,Benbadis SR,Vale FL

    更新日期:2012-03-01 00:00:00

  • Ipsilateral hemiparesis: the forgotten history of this paradoxical neurological sign.

    abstract:OBJECTIVE:Establishing the neurological localization doctrine for the contralateral hemispheric control of motor functions in the second half of the 19th century, researchers faced the challenge of recognizing false localizing signs, in particular paradoxical or ipsilateral hemiparesis (IH). Despite tremendous progress...

    journal_title:Neurosurgical focus

    pub_type: 历史文章,杂志文章

    doi:10.3171/2019.6.FOCUS19337

    authors: Carrasco-Moro R,Castro-Dufourny I,Martínez-San Millán JS,Cabañes-Martínez L,Pascual JM

    更新日期:2019-09-01 00:00:00

  • Deep brain stimulation: current and future perspectives.

    abstract::Deep brain stimulation (DBS) has been used to treat various neurological and psychiatric disorders. Over the years, the most suitable surgical candidates and targets for some of these conditions have been characterized and the benefits of DBS well demonstrated in double-blinded randomized trials. This review will disc...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/2009.4.FOCUS0982

    authors: Awan NR,Lozano A,Hamani C

    更新日期:2009-07-01 00:00:00

  • What neurosurgeons should do to succeed in tomorrow's scientific and socioeconomic environment.

    abstract::There will be major scientific advances and socioeconomic changes in the 21st century that will influence the development of medicine and neurosurgery. These changes will affect those in academic medical centers and the private practitioners of medicine and neurosurgery. Neurosurgeons' philosophy and practice methods ...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/foc.2002.12.4.10

    authors: Ausman JI,Pawl RP

    更新日期:2002-04-15 00:00:00

  • Delayed central nervous system superficial siderosis following brachial plexus avulsion injury. Report of three cases.

    abstract::Chronic subarachnoid hemorrhage may cause deposition of hemosiderin on the leptomeninges and subpial layers of the neuraxis, leading to superficial siderosis (SS). The symptoms and signs of SS are progressive and fatal. Exploration of potential sites responsible for intrathecal bleeding and subsequent hemosiderin depo...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/foc.2004.16.5.11

    authors: Cohen-Gadol AA,Krauss WE,Spinner RJ

    更新日期:2004-05-15 00:00:00

  • Induction of a therapeutic antitumor immunological response by intratumoral injection of genetically engineered Semliki Forest virus to produce interleukin-12.

    abstract:OBJECT:The authors investigated immunogene therapy for malignant glioma to determine whether its therapeutic efficacy could be improved. METHODS:Four groups of 203-glioma-bearing mice were treated with injections of phosphate-buffered saline, Semliki Forest virus (SFV)-LacZ, retrovirus vector DFG-interleukin (IL)-12, ...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/foc.2000.9.6.8

    authors: Yamanaka R,Zullo SA,Tanaka R,Ramsey J,Blaese M,Xanthopoulos KG

    更新日期:2000-12-15 00:00:00

  • Growing up with spina bifida: bridging the gaps in the transition of care from childhood to adulthood.

    abstract::Spina bifida is the most common nonchromosomal birth defect, resulting in permanent disability of multiple organ systems, yet compatible with long-term survival. Important advances across various disciplines have now improved survival among the spina bifida population. Although the majority of individuals living with ...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2019.7.FOCUS19441

    authors: Patel SK,Staarmann B,Heilman A,Mains A,Woodward J,Bierbrauer KS

    更新日期:2019-10-01 00:00:00

  • Atypical tumors of the facial nerve: case series and review of the literature.

    abstract:OBJECT:The authors present a series of 4 patients with rare facial nerve tumors. The relevant literature is reviewed and is discussed regarding diagnostic features, the role of operative management, and surgical approach. METHODS:A retrospective chart review was conducted for patients with tumors of the facial nerve t...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/2013.1.FOCUS12380

    authors: Ross L,Drazin D,Eboli P,Lekovic GP

    更新日期:2013-03-01 00:00:00

  • The history of brain retractors throughout the development of neurological surgery.

    abstract::Early neurosurgical procedures dealt mainly with treatment of head trauma, especially skull fractures. Since the early medical writings by Hippocrates, a great deal of respect was given to the dura mater, and many other surgeons warned against violating the dura. It was not until the 19th century that neurosurgeons st...

    journal_title:Neurosurgical focus

    pub_type: 历史文章,杂志文章

    doi:10.3171/2014.2.FOCUS13564

    authors: Assina R,Rubino S,Sarris CE,Gandhi CD,Prestigiacomo CJ

    更新日期:2014-04-01 00:00:00

  • Lumbosacral ependymomas: a review of the management of intradural and extradural tumors.

    abstract:OBJECT:The goal of this study was to review the management of intra- and extradural ependymomas. Spinal ependymomas most commonly occur as intramedullary tumors throughout the spinal axis. In the lumbosacral region, ependymomas are most commonly associated with the conus medullaris and cauda equina, but can also occur ...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/foc.2003.15.5.13

    authors: Fassett DR,Schmidt MH

    更新日期:2003-11-15 00:00:00

  • An ancestor of the stereotactic atlases: the Tabulae Anatomicae of Bartolomeo Eustachio.

    abstract::The authors report the history of the Tabulae Anatomicae of Bartolomeo Eustachio (ca. 1510-1574). In the tables, the anatomical illustrations were drawn inside a numerical frame, with pairs of numbers on the y- and x-axes to identify single anatomical details in the reference table. The measures and the references cou...

    journal_title:Neurosurgical focus

    pub_type: 传,历史文章,杂志文章

    doi:10.3171/2019.6.FOCUS19339

    authors: Dario A,Armocida GO,Locatelli D

    更新日期:2019-09-01 00:00:00

  • Carotid endarterectomy: current indications for surgery.

    abstract::The study of carotid artery occlusive disease interventions can be divided clinically into the treatment of asymptomatic and symptomatic diseases. Clinical trials that have studied or are currently studying asymptomatic disease include: the Carotid Artery Stenosis with Asymptomatic Narrowing Operation Versus Aspirin s...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:

    authors: Brennan JJ,Loftus CM

    更新日期:1998-12-15 00:00:00

  • The impact of the reserve military neurosurgeon: practice, community, and service.

    abstract::OBJECTIVEPapers from 2002 to 2017 have highlighted consistent unique socioeconomic challenges and opportunities facing military neurosurgeons. Here, the authors focus on the reserve military neurosurgeon who carries the dual mission of both civilian and military responsibilities.METHODSSurvey solicitation of current a...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2018.9.FOCUS18378

    authors: Menger R,Mundell BF,Robbins JW,Letarte P,Bell R,in conjunction with Council of State Neurosurgical Societies and AANS\/CNS Joint Committee of Military Neurosurgeons.

    更新日期:2018-12-01 00:00:00