Induction of a therapeutic antitumor immunological response by intratumoral injection of genetically engineered Semliki Forest virus to produce interleukin-12.

abstract：:Trepanation is the process by which a hole is drilled into the skull, exposing the intracranial contents for either medical or mystical purposes. It represents one of the oldest surgical procedures, and its practice was widespread in many ancient cultures and several parts of the world. Trepanation was used in ancient...

journal_title：Neurosurgical focus

authors： Missios S

更新日期：2007-01-01 00:00:00

abstract：:The development of less invasive methods to evacuate intracerebral hematomas (ICHs) has improved outcome in patients with traumatic brain injury. Eighteen patients with ICHs underwent surgery via one of two methods: stereotactic endoscopic removal (SER) or stereotactic catheter drainage (SCD). The outcome results were...

journal_title：Neurosurgical focus

authors： Kim MH,Song JH,Kim SH,Park DB,Shin KM

更新日期：1996-10-15 00:00:00

abstract：:OBJECTIVE The long-term effects on adjacent-segment pathology after nonfusion dynamic stabilization is unclear, and, in particular, changes at the adjacent facet joints have not been reported in a clinical study. This study aims to compare changes in the adjacent facet joints after lumbar spinal surgery. METHODS Patie...

journal_title：Neurosurgical focus

authors： Lee SE,Jahng TA,Kim HJ

更新日期：2016-01-01 00:00:00

abstract：:The craniocervical junction (CCJ) functions within a complicated regional anatomy necessary to protect and support vital neurovascular structures. In select instances, vascular pathology can be attributed to this complicated interplay of motion and structure found within this narrow space. The authors report 3 cases o...

journal_title：Neurosurgical focus

authors： Ravindra VM,Neil JA,Mazur MD,Park MS,Couldwell WT,Taussky P

更新日期：2015-04-01 00:00:00

abstract：:OBJECTIVE Anterior skull base meningiomas are benign lesions that cause neurological symptoms through mass effect on adjacent neurovascular structures. While traditional transcranial approaches have proven to be effective at removing these tumors, minimally invasive approaches that involve using an endoscope offer the...

journal_title：Neurosurgical focus

authors： Ottenhausen M,Rumalla K,Alalade AF,Nair P,La Corte E,Younus I,Forbes JA,Ben Nsir A,Banu MA,Tsiouris AJ,Schwartz TH

更新日期：2018-04-01 00:00:00

abstract：:Deep brain stimulation (DBS) has been reported to have beneficial effects in severe, treatment-refractory cases of obsessive-compulsive disorder (OCD) and Tourette syndrome (TS). In this report, the authors present the first case in which DBS was used to treat the neuropsychiatric symptoms of Kleefstra syndrome, a rar...

journal_title：Neurosurgical focus

authors： Segar DJ,Chodakiewitz YG,Torabi R,Cosgrove GR

更新日期：2015-06-01 00:00:00

abstract：:Arteriovenous malformation (AVM) presenting with epilepsy significantly impacts patient quality of life, and it should be considered very much a seizure disorder. Although hemorrhage prevention is the primary treatment aim of AVM surgery, seizure control should also be at the forefront of therapeutic management. Sever...

journal_title：Neurosurgical focus

authors： Soldozy S,Norat P,Yağmurlu K,Sokolowski JD,Sharifi KA,Tvrdik P,Park MS,Kalani MYS

更新日期：2020-04-01 00:00:00

abstract：OBJECT:Using strict biochemical remission criteria, the authors assessed surgical outcomes after endoscopic transsphenoidal resection of growth hormone (GH)-secreting pituitary adenomas and identified preoperative factors that significantly influence the rate of remission. METHODS:A retrospective review of a prospecti...

journal_title：Neurosurgical focus

authors： Campbell PG,Kenning E,Andrews DW,Yadla S,Rosen M,Evans JJ

更新日期：2010-10-01 00:00:00

abstract：:Iatrogenic intervertebral disc space infection is encountered following microsurgical discectomy, percutaneous laser disc decompression, automated percutaneous lumbar nucleotomy operations, and discography. The purpose of this paper is to present a case report and review the literature on the uncommon origins of pyoge...

journal_title：Neurosurgical focus

authors： Taşdemiroğlu E,Sengöz A,Bagatur E

更新日期：2004-06-15 00:00:00

abstract：:There is growing evidence to suggest that pregnancy may increase the risk of hemorrhage from cavernous malformations (CMs). In the present case, a 21-year-old primigravida was admitted to the authors' neurosurgical service after a cesarean section. Three weeks before admission she had experienced rapidly progressive b...

journal_title：Neurosurgical focus

authors： Safavi-Abbasi S,Feiz-Erfan I,Spetzler RF,Kim L,Dogan S,Porter RW,Sonntag VK

更新日期：2006-07-15 00:00:00

abstract：:During the past 20 years, the traditional supportive treatment for stroke has been radically transformed by advances in catheter technologies and a cohort of prominent randomized controlled trials that unequivocally demonstrated significant improvement in stroke outcomes with timely endovascular intervention. However,...

journal_title：Neurosurgical focus

authors： Vuong SM,Carroll CP,Tackla RD,Jeong WJ,Ringer AJ

更新日期：2017-04-01 00:00:00

abstract：OBJECT:Intracranial hypotension (ICH) can present with a wide variety of visual symptoms and findings. Deficits in visual acuity and visual fields as well as ophthalmoplegia due to cranial nerve dysfunction have been frequently described. The aim of this review was to identify the most commonly reported ocular manifest...

journal_title：Neurosurgical focus

authors： Zada G,Solomon TC,Giannotta SL

更新日期：2007-01-01 00:00:00

abstract：OBJECT:The authors present a series of 4 patients with rare facial nerve tumors. The relevant literature is reviewed and is discussed regarding diagnostic features, the role of operative management, and surgical approach. METHODS:A retrospective chart review was conducted for patients with tumors of the facial nerve t...

journal_title：Neurosurgical focus

authors： Ross L,Drazin D,Eboli P,Lekovic GP

更新日期：2013-03-01 00:00:00

abstract：:Neuroimaging is an indispensable tool in the workup and management of patients with neurological disorders. Arterial spin labeling (ASL) is an imaging modality that permits the examination of blood flow and perfusion without the need for contrast injection. Noninvasive in nature, ASL provides a feasible alternative to...

journal_title：Neurosurgical focus

authors： Soldozy S,Galindo J,Snyder H,Ali Y,Norat P,Yağmurlu K,Sokolowski JD,Sharifi K,Tvrdik P,Park MS,Kalani MYS

更新日期：2019-12-01 00:00:00

abstract：:Dumbbell tumors of the cervical spine can present considerable management challenges related to adequate exposure of both intraspinal and paraspinal tumor components, potential injury to the vertebral artery, and spinal stability. This video demonstrates the microsurgical removal of a large cervical dumbbell schwannom...

journal_title：Neurosurgical focus

authors： McCormick PC

更新日期：2014-09-01 00:00:00

abstract：OBJECT:Glioblastoma multiforme (GBM) is a rare tumor whose prognosis has remained poor over the years despite innovative radio- and chemotherapies, and important technical advances in neurosurgery such as intraoperative imaging, fluorescence, Cavitron ultrasonic surgical aspirator, and neuronavigation. Particular atten...

journal_title：Neurosurgical focus

authors： Pompili A,Telera S,Villani V,Pace A

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:Tractography is a useful technique that is standardly applied to visualize subcortical pathways. However, brain shift hampers tractography use during the course of surgery. While intraoperative MRI (ioMRI) has been shown to be beneficial for use in oncology, intraoperative tractography can rarely be performed...

journal_title：Neurosurgical focus

authors： Ille S,Schroeder A,Wagner A,Negwer C,Kreiser K,Meyer B,Krieg SM

更新日期：2021-01-01 00:00:00

abstract：:OBJECTIVE Tectal gliomas constitute a rare and inhomogeneous group of lesions with an uncertain clinical course. Because these supposedly benign tumors are frequently followed up by observation over many years, the authors undertook this analysis of their own case series in an effort to demonstrate that the clinical c...

journal_title：Neurosurgical focus

authors： Mohme M,Fritzsche FS,Mende KC,Matschke J,Löbel U,Kammler G,Westphal M,Emami P,Martens T

更新日期：2018-06-01 00:00:00

abstract：OBJECT:The authors undertook this study to examine the surgical approaches used to treat posterior petrous bone meningiomas at a single institution and retrospectively evaluate their surgical strategy based on a previously published classification. METHODS:Cases in which craniotomies were performed to treat posterior ...

journal_title：Neurosurgical focus

authors： Roche PH,Lubrano V,Noudel R,Melot A,Régis J

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:The COVID-19 pandemic has forced medical professionals throughout the world to adapt to the changing medical scenario. The objective of this survey was to assess the change in neurosurgical training in India following the COVID-19 pandemic. METHODS:Between May 7, 2020, and May 16, 2020, a validated questionn...

journal_title：Neurosurgical focus

authors： Dash C,Venkataram T,Goyal N,Chaturvedi J,Raheja A,Singla R,Sardhara J,Gupta R

更新日期：2020-12-01 00:00:00

abstract：:Focal cortical dysplasias (FCDs) are congenital malformations of cortical development that are a frequent cause of refractory epilepsy in both children and adults. With advances in structural and functional neuroimaging, these lesions are increasingly being identified as a cause of intractable epilepsy in patients und...

journal_title：Neurosurgical focus

authors： Diaz RJ,Sherman EM,Hader WJ

更新日期：2008-09-01 00:00:00

abstract：OBJECT:The goal in this study was to determine if there was a change in intracranial venous diameters after endovascular treatment of carotid distribution vasospasm caused by subarachnoid hemorrhage. METHODS:The venous diameters were measured in all patients who received intraarterial papaverine and/or balloon angiopl...

journal_title：Neurosurgical focus

authors： Elsayed AA,Moran CJ,Cross DT 3rd,Derdeyn CP,Pilgram TK,Milburn JM,Dacey RG Jr,Diringer MN Jr

更新日期：2006-09-15 00:00:00

abstract：OBJECT:Lamotrigine is an antiepileptic drug that inhibits presynaptic voltage-gated sodium channels and reduces the presynaptic release of glutamate in pathological states. Neuroprotective effects of this drug have already been demonstrated in cerebral ischemia models. The aim of the present study was to determine the ...

journal_title：Neurosurgical focus

authors： Tufan K,Oztanir N,Ofluoglu E,Ozogul C,Uzum N,Dursun A,Pasaoglu H,Pasaoglu A

更新日期：2008-01-01 00:00:00

abstract：:OBJECTIVE The American Association of Neurological Surgeons launched the Quality Outcomes Database (QOD), a prospective longitudinal registry that includes demographic, clinical, and patient-reported outcome (PRO) data, to measure the safety and quality of neurosurgical procedures, including spinal surgery. Differing ...

journal_title：Neurosurgical focus

authors： Chan AK,Bisson EF,Bydon M,Glassman SD,Foley KT,Potts EA,Shaffrey CI,Shaffrey ME,Coric D,Knightly JJ,Park P,Fu KM,Slotkin JR,Asher AL,Virk MS,Kerezoudis P,Chotai S,DiGiorgio AM,Chan AY,Haid RW,Mummaneni PV

更新日期：2018-01-01 00:00:00

abstract：:Chronic subarachnoid hemorrhage may cause deposition of hemosiderin on the leptomeninges and subpial layers of the neuraxis, leading to superficial siderosis (SS). The symptoms and signs of SS are progressive and fatal. Exploration of potential sites responsible for intrathecal bleeding and subsequent hemosiderin depo...

journal_title：Neurosurgical focus

authors： Cohen-Gadol AA,Krauss WE,Spinner RJ

更新日期：2004-05-15 00:00:00

abstract：:Interventional neuroradiology is a less invasive modality than open neurosurgery for the treatment of a wide range of neurovascular disorders. Refinements in technique and improvements in the design of microcatheters, guide wires, and embolic materials have yielded superior clinical outcomes and provided an impetus to...

journal_title：Neurosurgical focus

authors： Ng PP,Higashida RT,Cullen S,Malek R,Halbach VV,Dowd CF

更新日期：2003-10-15 00:00:00

abstract：OBJECT:Jugular foramen tumors are rare skull base lesions that present diagnostic and complex management problems. The purpose of this study was to evaluate a series of patients with jugular foramen tumors who were surgically treated in the past 16 years, and to analyze the surgical technique, complications, and outcom...

journal_title：Neurosurgical focus

authors： Ramina R,Maniglia JJ,Fernandes YB,Paschoal JR,Pfeilsticker LN,Neto MC,Borges G

更新日期：2004-08-15 00:00:00

abstract：:The goals of this study were to analyze the effect of pallidotomy on parkinsonian tremor and to ascertain whether an association exists between microrecording findings and tremor outcome. Forty-four patients with Parkinson's disease (PD) who had drug-induced dyskinesia, bradykinesia, rigidity, and tremor underwent pos...

journal_title：Neurosurgical focus

authors： Taha JM,Favre J,Baumann TK,Burchiel KJ

更新日期：1997-03-15 00:00:00

abstract：:Foramen magnum meningiomas (FMMs) are slow growing, most often intradural and extramedullary tumors that pose significant challenges to the skull base neurosurgeon. The indolent clinical course of FMMs and their insidious onset of symptoms are important factors that contribute to delayed diagnosis and relative large s...

journal_title：Neurosurgical focus

authors： Flores BC,Boudreaux BP,Klinger DR,Mickey BE,Barnett SL

更新日期：2013-12-01 00:00:00

abstract：OBJECT:The direct transnasal transsphenoidal approach to the sellar region has become a widely adopted surgical procedure among neurosurgeons and ear, nose, and throat specialists. Nasal complications and their incidence have been investigated, but a systematic testing of olfactory disturbance has not previously been p...

journal_title：Neurosurgical focus

authors： Actor B,Sarnthein J,Prömmel P,Holzmann D,Bernays RL

更新日期：2010-10-01 00:00:00