Pokemon expression in malignant glioma: an application of bioinformatics methods.

Abstract:

OBJECT:In this report the authors review the role of bioinformatics in the design of a research project in which the molecular genetics of malignant glioma were studied. A project to characterize Pokemon expression in malignant glioma was developed, refined, and implemented using bioinformatics methods. METHODS:Using the resources available from the National Center for Biotechnology Information, the messenger RNA (mRNA) sequence for Pokemon was determined. With this information and online primer design tools, novel primers were designed that would specifically amplify Pokemon mRNA by using reverse transcription-polymerase chain reaction assays. CONCLUSIONS:The promise of bioinformatics is in the rapid and widespread dissemination and analysis of genomic information. This information is then used in research investigating the genetic basis of disease. In this paper the authors review the bioinformatics methods used in their study of Pokemon expression in malignant glioma.

journal_name

Neurosurg Focus

journal_title

Neurosurgical focus

authors

Rovin RA,Winn R

doi

10.3171/foc.2005.19.4.9

subject

Has Abstract

pub_date

2005-10-15 00:00:00

pages

E8

issue

4

issn

1092-0684

pii

190408

journal_volume

19

pub_type

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