当前位置： SCI文献检索 > DISEASES OF THE ESOPHAGUS期刊下所有文献 > Changing role of in vivo models in columnar-lined lower esophagus.

Changing role of in vivo models in columnar-lined lower esophagus.

Abstract：

:Columnar-lined lower esophagus (CLE) or Barrett's esophagus (BE) is caused by chronic reflux of the gastrointestinal tract and can progress to invasive adenocarcinoma. However, the pathophysiology, cell of origin, and management of this condition is incompletely understood. This review evaluates the role of in vivo models in resolving these debates. A search was performed on the Ovid and Pub Medline for 1964-2001 and Cochrane Collaboration. The keywords used were adenocarcinoma, animal model, Barrett's esophagus, columnar-lined esophagus, esophageal neoplasms, and esophageal carcinogenesis. All relevant papers were scrutinized and an attempt at tabulation was made. In vivo models have been used at several stages of debate on the pathophysiology of BE. They provide conclusive evidence for its acquired nature secondary to duodenogastroesophageal reflux. The cell of origin of experimental BE may arise from adjacent columnar epithelium, basal layer multipotent cells, or esophageal glands. Experimental work on BE is lacking in assessing therapeutic modalities.

journal_name

Dis Esophagus

journal_title

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors

Koak Y,Winslet M

doi

10.1046/j.1442-2050.2002.00268.x

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

271-7

issue

4

eissn

1120-8694

issn

1442-2050

pii

268

journal_volume

15

pub_type

杂志文章,评审

相关文献

DISEASES OF THE ESOPHAGUS文献大全
  • Heller's esophagomyotomy with or without a 360 degrees floppy Nissen fundoplication for achalasia. Long-term results from a prospective randomized study.

    abstract：:Heller's esophagomyotomy relieves dysphagia but does not restore esophageal peristalsis. The myotomy may induce reflux and the addition of a 360 degrees fundoplication may be hazardous with regard to the remaining aperistaltic esophagus. The aim of this prospectively randomized clinical trial was to compare the outcom...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1111/j.1442-2050.2003.00348.x

    authors： Falkenback D,Johansson J,Oberg S,Kjellin A,Wenner J,Zilling T,Johnsson F,Von Holstein CS,Walther B

    更新日期：2003-01-01 00:00:00

  • Comparative retrospective study on the use of plastic prostheses and self-expanding metal stents in the palliative treatment of malignant strictures of the esophagus and cardia.

    abstract：:Palliative treatment of malignant strictures of the esophagus and cardia is usually carried out by the endoscopic placement of a prosthesis. The aim of this retrospective study was to evaluate short- and long-term outcomes of the use of expandable stents, compared with conventional plastic prostheses. One hundred and ...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1046/j.1442-2050.2003.00308.x

    authors： Mosca F,Consoli A,Stracqualursi A,Persi A,Portale TR

    更新日期：2003-01-01 00:00:00

  • Proceedings from an international conference on ablation therapy for Barrett's mucosa: Brittany, France, 31 August - 2 September 1997.

    abstract：:The increasing incidence of adenocarcinoma of the lower esophagus and cardia arising in Barrett's metaplastic epithelium continues to be of great concern because medical and surgical efforts to reverse the process have been disappointing. A potential answer to the problem is removal of the metaplastic epithelium. Mode...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type：

    doi：10.1093/dote/11.1.1

    authors： Bremner CG,Demeester TR

    更新日期：2017-11-01 00:00:00

  • Definitive concomitant chemoradiotherapy with docetaxel and cisplatin in squamous esophageal carcinoma.

    abstract：:Chemoradiotherapy is a standard treatment for esophageal carcinoma. This study evaluated the docetaxel-based definitive concomitant chemoradiotherapy in patients with esophageal squamous cell carcinoma to determine its clinical response and overall survival. In this unicenter trail, we enrolled 59 patients with histol...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 临床试验,杂志文章

    doi：10.1111/j.1442-2050.2009.01003.x

    authors： Li QQ,Liu MZ,Hu YH,Liu H,He ZY,Lin HX

    更新日期：2010-04-01 00:00:00

  • Esophageal schistosomiasis in a patient with megaesophagus.

    abstract：:The authors report a case of schistosomiasis of uncommon location. A patient submitted to esophagectomy for Chagas' megaesophagus was found to have eggs of Schistosoma mansoni upon pathologic examination of the surgical specimen. The authors discuss the anatomopathological aspects of schistosomiasis, as well as its oc...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1093/dote/10.1.71

    authors： Gagliardi D,Corsi PR,Eckley CA,Marigo C,Fava J

    更新日期：1997-01-01 00:00:00

  • Successfully treated case of cervical abscess and mediastinitis due to esophageal perforation after gastrointestinal endoscopy.

    abstract：:Perforations of the esophagus are uncommon complications of flexible gastrointestinal endoscopy. Perforations after endoscopy are likely to occur in the cervical esophagus, where fiber insertion is difficult anatomically. The diagnosis should be made as soon as possible, because mediastinitis and sepsis frequently dev...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1046/j.1442-2050.2002.00253.x

    authors： Sato S,Kajiyama Y,Kuniyasu T,Machida M,Ouchi K,Sakai N,Sakamoto S,Iwanuma Y,Kamano T,Okamura S,Nagahama A,Tsurumaru M

    更新日期：2002-01-01 00:00:00

  • Benign esophagorespiratory fistula: a case series and a novel technique of definitive management.

    abstract：:Benign esophagorespiratory fistula is a relatively rare condition in adults that poses a technical challenge to manage. This case series describes our experience in the treatment of benign esophagorespiratory fistula in 12 adults. A retrospective review of case records of 12 patients with benign esophagorespiratory fi...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2012.01347.x

    authors： Deshpande G,Samarasam I,Banerjee S,Gnanamuthu RB,Chandran S,Mathew G

    更新日期：2013-02-01 00:00:00

  • Quantitative endoscopy in the chemoprevention of Barrett's Esophagus Trial.

    abstract：:The Chemoprevention for Barrett's Esophagus Trial (CBET) was a phase IIb, multicenter, randomized, placebo-controlled trial of celecoxib in patients with Barrett's esophagus. The overall outcome of the study was that there were no significant differences in primary, secondary, or tertiary outcomes. The purpose of the ...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1111/j.1442-2050.2008.00835.x

    authors： Shar AO,Gaudard MA,Heath EI,Forastiere AA,Yang VW,Sontag SJ

    更新日期：2008-01-01 00:00:00

  • Psychological impact of esophageal atresia: review of the research and clinical evidence.

    abstract：:Esophageal atresia (EA) occurs in one out of 2500 to 4500 live births. As the vast majority of infants are now surviving neonatal corrective surgery, the focus has shifted from mortality to morbidity associated with EA. However, little is known about its psychological morbidity. This paper synthesizes research and cli...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章,评审

    doi：10.1111/dote.12056

    authors： Caplan A

    更新日期：2013-05-01 00:00:00

  • Angiolipoma of the esophagus: a rare clinical dilemma.

    abstract：:Benign tumors of the esophagus are a rare but diverse group of lesions. Although non-malignant in biology, their presence can cause significant morbidity, including dysphagia, bleeding, gastrointestinal obstruction, and even asphyxiation. Diagnosis is frequently made using radiographic and endoscopic means, even in th...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2006.00567.x

    authors： Jensen EH,Klapman JB,Kelley ST

    更新日期：2006-01-01 00:00:00

  • Gastric fundus tension before and after division of the short gastric vessels in a cadaveric model of fundoplication.

    abstract：:Short gastric vessels (SGV) division is a controversial topic in antireflux surgery. Some surgeons do not divide the SGV routinely to perform a fundoplication; however, excessive tension of the gastric fundus (GF) forces this procedure necessary in some cases. This study aims to evaluate in a cadaveric model of Nissen...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2009.00945.x

    authors： Szor DJ,Herbella FA,Bonini AL,Moreno DG,Del Grande JC

    更新日期：2009-01-01 00:00:00

  • Achalasia and chronic opiate use: innocent bystanders or associated conditions?

    abstract：:High-resolution manometry identifies three subtypes of achalasia. However, type 3 differs from classic achalasia. Although opiates affect esophageal motility, opiate use and achalasia have not been studied. Patients with a new diagnosis of achalasia at Mayo Clinic Rochester between June 1, 2012 and January 3, 2014 wer...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/dote.12291

    authors： Ravi K,Murray JA,Geno DM,Katzka DA

    更新日期：2016-01-01 00:00:00

  • Esophagectomy for failed endoscopic therapy in patients with high-grade dysplasia or intramucosal carcinoma.

    abstract：:Endoscopic therapy (ablation +/- endoscopic resection) for high-grade dysplasia and/or intramucosal carcinoma (IMC) of the esophagus has demonstrated promising results. However, there is a concern that a curable, local disease may progress to systemic disease with repeated endotherapy. We performed a retrospective rev...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/dote.12096

    authors： Hunt BM,Louie BE,Dunst CM,Lipham JC,Farivar AS,Sharata A,Aye RW

    更新日期：2014-05-01 00:00:00

  • Same-day discharge in benign esophageal surgery: a prospective cohort study.

    abstract：:Day-case esophageal surgery has been demonstrated to be safe in small prospective cohorts and only for laparoscopic fundoplication. The aims of this study are to assess the feasibility and safety of a large series of esophageal day-case surgeries, including laparoscopic Nissen fundoplication (LNF), Zenker diverticulec...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1093/dote/dow036

    authors： Desbeaux A,Gronnier C,Piessen G,Vanderbeken M,Ruolt N,Triboulet JP,Mariette C

    更新日期：2017-04-01 00:00:00

  • Treatment choices and outcomes of patients with manometrically diagnosed achalasia.

    abstract：:This prospective population-based study was designed to evaluate treatment choices in patients with new manometrically diagnosed achalasia and their outcomes. Patients referred to the esophageal function laboratory were enrolled after a new manometric diagnosis of achalasia. Patients completed an initial achalasia sym...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/dote.12348

    authors： Yeung JC,Finley C,Hanna WC,Miller L,Ferri L,Urbach DR,Darling GE

    更新日期：2016-07-01 00:00:00

  • Expression of p53, bcl-2, and bax as predictors of response to radiotherapy in esophageal cancer.

    abstract：:The sensitivity of cancers to radiotherapy or chemotherapy may be influenced by susceptibility to apoptosis. We evaluated whether expression of three proteins regulating apoptosis, p53, bcl-2, and bax, could predict the effect of radiotherapy in esophageal cancers. We used immunohistochemical staining for these protei...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1046/j.1442-2050.2000.00097.x

    authors： Shimoji H,Miyazato H,Nakachi A,Kuniyoshi S,Isa T,Shiraishi M,Muto Y,Toda T

    更新日期：2000-01-01 00:00:00

  • Jackhammer esophagus: high-resolution manometry and therapeutic approach using peroral endoscopic myotomy (POEM).

    abstract：:We present the first report on peroral endoscopic myotomy (POEM) in the treatment of jackhammer esophagus. A 34-year-old female patient was newly diagnosed with a jackhammer esophagus. After failure of medical treatment, the patient underwent POEM procedure for myotomy of the spastic segment. Postoperatively, a mild e...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type：

    doi：10.1111/dote.12182

    authors： Kandulski A,Fuchs KH,Weigt J,Malfertheiner P

    更新日期：2016-08-01 00:00:00

  • Management of eosinophilic esophagitis is often discordant with guidelines and not patient-centered: results of a survey of gastroenterologists.

    abstract：:Published guidelines for the management of eosinophilic esophagitis (EoE) recommend an initial trial of proton pump inhibitors (PPI), histologic assessment for response to therapy, and tailoring treatments to patient needs and provider resources. Effectiveness studies directly comparing therapies are lacking, leaving ...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1093/dote/doy133

    authors： Chang JW,Saini SD,Mellinger JL,Chen JW,Zikmund-Fisher BJ,Rubenstein JH

    更新日期：2019-06-01 00:00:00

  • Accuracy and interrater reliability for the diagnosis of Barrett's neoplasia among users of a novel, portable high-resolution microendoscope.

    abstract：:The high-resolution microendoscope (HRME) is a novel imaging modality that may be useful in the surveillance of Barrett's esophagus in low-resource or community-based settings. In order to assess accuracy and interrater reliability of microendoscopists in identifying Barrett's-associated neoplasia using HRME images, w...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/dote.12040

    authors： Vila PM,Kingsley MJ,Polydorides AD,Protano MA,Pierce MC,Sauk J,Kim MK,Patel K,Godbold JH,Waye JD,Richards-Kortum R,Anandasabapathy S

    更新日期：2014-01-01 00:00:00

  • Long esophagomyotomy for diffuse esophageal spasm and related disorders: an historical overview.

    abstract：:In summary, the role of long esophagomyotomy for patients with DES and related motor disorders remains controversial. The results are poorer than those following esophagomyotomy for achalasia, and long-term postoperative follow-up of these patients is essential because early good results may be misleading. Two methods...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 历史文章,杂志文章

    doi：10.1093/dote/11.4.210

    authors： Ellis FH Jr

    更新日期：1998-10-01 00:00:00

  • Epidemiology, diagnosis, and management of esophageal perforations: systematic review.

    abstract：:We performed a systematic review of epidemiological, diagnostic, and therapeutic outcomes of esophageal perforations. A systematic review was performed in PubMed database using the key-phrase 'esophageal perforation'. All studies regarding acute esophageal perforations were reviewed and parameters of epidemiology, dia...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章,评审

    doi：10.1093/dote/dox013

    authors： Sdralis EIK,Petousis S,Rashid F,Lorenzi B,Charalabopoulos A

    更新日期：2017-08-01 00:00:00

  • Characterization of tissue chromogranin A (CgA) immunostaining and clinicohistopathological changes for the 125 Chinese patients with primary small cell carcinoma of the esophagus.

    abstract：:The rarity of primary small cell carcinoma of the esophagus (PSCE) has limited the clinical feature and survival analysis with large sample size. Tissue chromogranin A (CgA) protein expression has been reported to be a useful biomarker for diagnosing PSCE. Interestingly, recent studies have indicated tissue CgA as a s...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1093/dote/dox041

    authors： Ku JW,Zhang DY,Song X,Li XM,Zhao XK,Lv S,Hu SJ,Cheng R,Zhou FY,Wu HF,Wang LD

    更新日期：2017-08-01 00:00:00

  • Palliation of malignant dysphagia by laser therapy.

    abstract：:The outcome of 211 patients undergoing laser therapy as palliation for inoperable carcinoma of the esophagus is presented. The median age was 73 (range 44-97). The histology was adenocarcinoma for 127 patients and squamous-cell carcinoma for 84 patients. For 133 patients, laser was the only therapy while 56 patients h...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1093/dote/10.4.243

    authors： Savage AP,Baigrie RJ,Cobb RA,Barr H,Kettlewell MG

    更新日期：1997-10-01 00:00:00

  • Respiratory management and outcome of non-malignant tracheo-bronchial fistula following esophagectomy.

    abstract：:Tracheo-bronchial lesions with air leak are rare but a catastrophic complications of esophageal resections. We analyzed the management and outcome of 31 patients who developed a non-malignant lesion of the trachea or main stem bronchus after esophagectomy for esophageal cancer. All patients initially required endotrac...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 临床试验,杂志文章

    doi：10.1093/dote/11.2.125

    authors： Bartels HE,Stein HJ,Siewert JR

    更新日期：1998-04-01 00:00:00

  • Neoadjuvant chemoradiotherapy followed by esophagectomy for initially resectable squamous cell carcinoma of the esophagus with multiple lymph node metastasis.

    abstract：:Neoadjuvant chemoradiotherapy (CRT) was expected to improve surgical curability and prognosis for advanced esophageal cancer. However, the clinical efficacy of neoadjuvant CRT followed by esophagectomy with three-field lymphadenectomy (3FL) for initially resectable esophageal squamous cell carcinoma (SCC) remains uncl...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1111/j.1442-2050.2005.00521.x

    authors： Nabeya Y,Ochiai T,Matsubara H,Okazumi S,Shiratori T,Shuto K,Aoki T,Miyazaki S,Gunji Y,Uno T,Ito H,Shimada H

    更新日期：2005-01-01 00:00:00

  • Outcomes of definitive chemoradiation in patients with esophageal cancer.

    abstract：:The incidence of esophageal cancer has risen dramatically in the Western world. Although surgical resection of esophageal tumors is considered the cornerstone of curative approaches in localized esophageal cancer, approximately 40% of patients who undergo chemoradiation followed by surgery will experience a recurrence...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章,评审

    doi：10.1111/dote.12506

    authors： Mikhail S,Wei L,Salem ME,Bekaii-Saab T

    更新日期：2017-02-01 00:00:00

  • Psychological and emotional aspects of gastroesophageal reflux disease.

    abstract：:A synergy exists between the psychological and physiological aspects of esophageal and other gastrointestinal symptoms. Based on a biopsychosocial model of disease, several multidisciplinary concepts of interventions in gastrointestinal disorders have been evaluated. The role of psychological factors in gastroesophage...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章,评审

    doi：10.1046/j.1442-2050.2002.00261.x

    authors： Kamolz T,Velanovich V

    更新日期：2002-01-01 00:00:00

  • Outcome of thoracoscopic repair of type-C esophageal atresia: a single-center experience from North Africa.

    abstract：:Thoracoscopic repair of esophageal atresia is gaining popularity worldwide attributable to availability and advances in minimally invasive instruments. In this report, we presented our experience with thoracoscopic esophageal atresia/tracheoesophageal fistula (EA/TEF) repair in our tertiary care institute. A prospecti...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1093/dote/doaa001

    authors： Elbarbary MM,Shalaby A,Elseoudi M,Seleim HM,Ragab M,Fares AE,Khairy D,Wishahy AMK,Alkonaiesy RM,Eltagy G,Bahaaeldin K

    更新日期：2020-02-12 00:00:00

  • Simultaneous leiomyosarcoma and squamous cell carcinoma of the esophagus: report of a new case.

    abstract：:Leiomyosarcoma of the esophagus is an uncommon neoplasm of mesenchymal origin. The simultaneous occurrence of leiomyosarcoma and squamous cell carcinoma in the esophagus as separate tumors is a very rare event. We present a case leiomyosarcoma associated with squamous cell carcinoma that was diagnosed after surgical r...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1046/j.1442-2050.2001.00194.x

    authors： Eroğlu A,Kürkçüoğlu C,Karaoğlanoğlu N,Erdoğan F,Polat P

    更新日期：2001-01-01 00:00:00

  • Morbidity following salvage esophagectomy for squamous cell carcinoma: the MD Anderson experience.

    abstract：:The survival advantage associated with the addition of surgical therapy in esophageal squamous cell carcinoma (ESCC) patients who demonstrate a complete clinical response to chemoradiotherapy is unclear, and many institutions have adopted an organ-preserving strategy of selective surgery in this population. We sought ...

    journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type： 杂志文章

    doi：10.1093/dote/doz067

    authors： Mitchell KG,Nelson DB,Corsini EM,Vaporciyan AA,Antonoff MB,Mehran RJ,Rice DC,Roth JA,Sepesi B,Walsh GL,Bhutani MS,Maru DM,Wu CC,Nguyen QN,Ajani JA,Swisher SG,Hofstetter WL

    更新日期：2020-03-16 00:00:00