LncRNA SNHG9 is downregulated in osteoarthritis and inhibits chondrocyte apoptosis by downregulating miR-34a through methylation.

abstract：BACKGROUND:A body of evidence demonstrating changes to the glutaminergic system in tendinopathy has recently emerged. This hypothesis was further tested by studying the effects of glutamate on the tenocyte phenotype, and the impact of loading and exposure to glucocorticoids on the glutamate signaling machinery. METHOD...

journal_title：BMC musculoskeletal disorders

authors： Spang C,Backman LJ,Le Roux S,Chen J,Danielson P

更新日期：2017-05-25 00:00:00

abstract：BACKGROUND:Early femoral stem subsidence following a cementless THA is correlated with aseptic loosening of the femoral component. The short femoral stems allow bone sparing and implantation through a minimally invasive approach; however, due to their metaphyseal anchoring, they might demonstrate different subsidence p...

journal_title：BMC musculoskeletal disorders

authors： Schaer MO,Finsterwald M,Holweg I,Dimitriou D,Antoniadis A,Helmy N

更新日期：2019-12-12 00:00:00

abstract：BACKGROUND:Total Hip Replacement (THR) is an effective treatment for end-stage hip osteoarthritis. Since the introduction of total joint replacement, the effect on the Sexual Quality of Life (SQoL) following THR has been addressed in scant studies. The aim of our study was to systematically review the literature, to su...

journal_title：BMC musculoskeletal disorders

authors： Harmsen RT,Haanstra TM,Sierevelt IN,Jansma EP,Nolte PA,Nicolai MP,Wall PD,Van Royen BJ

更新日期：2016-05-04 00:00:00

abstract：BACKGROUND:Calcification of the medial collateral ligament (MCL) of the knee is a very rare disease. We report on a case of a patient with a calcifying lesion within the MCL and simultaneous calcifying tendinitis of the rotator cuff in both shoulders. CASE PRESENTATION:Calcification of the MCL was diagnosed both via x...

journal_title：BMC musculoskeletal disorders

authors： Kamawal Y,Steinert AF,Holzapfel BM,Rudert M,Barthel T

更新日期：2016-07-13 00:00:00

abstract：BACKGROUND:Patients with whiplash-associated disorders (WAD) have a generally favourable prognosis, yet some develop longstanding pain and disability. Predicting who will recover from WAD shortly after a traffic collision is very challenging for health care providers such as physical therapists. Therefore, we aimed to ...

journal_title：BMC musculoskeletal disorders

authors： Bohman T,Côté P,Boyle E,Cassidy JD,Carroll LJ,Skillgate E

更新日期：2012-12-29 00:00:00

abstract：BACKGROUND:ADAMTS (a disintegrin and metalloprotease with thrombospondin motifs) proteins play an important pathological role in matrix degeneration. Aggrecan degradation is a significant and critical event in early-stage osteoarthritis. To determine the effect of hemoglobin (Hb) on the ability of synovial tissues to p...

journal_title：BMC musculoskeletal disorders

authors： Tajima T,Sekimoto T,Yamaguchi N,Taniguchi N,Kurogi S,Maruyama M,Chosa E

更新日期：2017-11-14 00:00:00

abstract：BACKGROUND:Surgery is usually recommended for thoracolumbar fracture with neurologic deficit. However, traditional open posterior approach requires massive paraspinal muscles stripping, and the canal decompression may be limited and incomplete. We aimed to investigate a new approach via the Wiltse approach and the Kamb...

journal_title：BMC musculoskeletal disorders

authors： Zhang B,Zhou F,Wang L,Wang H,Jiang J,Guo Q,Lu X

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The prosthesis of contemporary total knee arthroplasty (TKA) has been modified to provide a more familiar environment for higher flexion angle of the replaced knee. The design modifications continue based on evidence reported in the literature. However, whether these modifications of the prosthesis design le...

journal_title：BMC musculoskeletal disorders

authors： Seo JG,Moon YW,Chang MJ,Jo BC,Park YB,Lim DS,Lee BH

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:Shoulder pain is the third most common reason for consultation with a physiotherapist and up to 26% of the general population might be expected to experience an episode at any one time. Disorders of the shoulder muscles and tendons (rotator cuff) are thought to be the commonest cause of this pain. The long-t...

journal_title：BMC musculoskeletal disorders

authors： Littlewood C,Ashton J,Mawson S,May S,Walters S

更新日期：2012-04-30 00:00:00

abstract：BACKGROUND:Distance running is a popular recreational exercise. It is a beneficial activity for health and well being. However, running may also cause injuries, especially of the lower extremities. In literature there is no agreement what intrinsic and extrinsic factors cause running related injuries (RRIs). In theory,...

journal_title：BMC musculoskeletal disorders

authors： Bredeweg SW,Zijlstra S,Buist I

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Juvenile idiopathic arthritis (JIA) refers to a number of rare chronic inflammatory diseases. Although JIA imposes a significant societal burden, limited data are available on the cost of JIA. The study's objective is to quantify the socioeconomic burden of JIA patients in the United Kingdom (UK), along with...

journal_title：BMC musculoskeletal disorders

authors： Angelis A,Kanavos P,López-Bastida J,Linertová R,Serrano-Aguilar P,BURQOL-RD Research Network.

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:The Hueter-Volkmann law describes growth principles around joints and joint deformation. It states that decreased stress leads to increased growth and that excessive stress leads to growth retardation. Aim of this study was to test the possible results of this principle by measuring the effect of dorsal hume...

journal_title：BMC musculoskeletal disorders

authors： van Gelein Vitringa VM,van Royen BJ,van der Sluijs JA

更新日期：2013-03-22 00:00:00

abstract：BACKGROUND:Lower extremity joint contractures have negative effects on gait in children with Duchenne muscular dystrophy (DMD). Thus, contracture prevention is essential for maintaining a patient's functional ability and an acceptable quality of life. This study investigated hip flexion (HF), knee flexion (KF), and ank...

journal_title：BMC musculoskeletal disorders

authors： Choi YA,Chun SM,Kim Y,Shin HI

更新日期：2018-08-16 00:00:00

abstract：BACKGROUND:The role of altered joint mechanics on cartilage degeneration in in vivo models has not been studied successfully due to a lack of pre-injury information. We aimed 1) to develop an accurate in vivo canine model to measure the changes in joint loading and T2 star (T2*) relaxation time before and after unilate...

journal_title：BMC musculoskeletal disorders

authors： Lee D,Hong KT,Lim TS,Lee E,Lee YH,Park JS,Kim W,Oh JH,Choi JA,Song Y

更新日期：2020-07-02 00:00:00

abstract：BACKGROUND:Osteochondroma is a benign tumor that occurs mainly at the metaphysis of long bones and seldom arises from carpal bones. We describe an extremely rare case of osteochondroma of the hamate without a typical cartilaginous cap and with a spiky bony protrusion in an elderly patient. CASE PRESENTATION:A 78-year-...

journal_title：BMC musculoskeletal disorders

authors： Motomiya M,Sakazaki T,Iwasaki N

更新日期：2020-04-13 00:00:00

abstract：BACKGROUND:Valid measures of physical activity are critical research tools. The objective of this study was to develop a Spanish translation of the Yale Physical Activity Survey, and to provide preliminary evidence of its validity in a population of Dominican patients with lower extremity arthritis. METHODS:A Dominica...

journal_title：BMC musculoskeletal disorders

authors： Katz JN,Perez MT,Niu NN,Dong Y,Brownlee SA,Elman SA,Stenquist DS,Santiago A,Sanchez ES,Collins JE

更新日期：2014-04-07 00:00:00

abstract：BACKGROUND:Lumbar microdiscectomy is the most commonly performed spinal surgery procedure, with over 300,000 cases performed annually in the United States alone. Traditionally, patients were advised to restrict post-operative activity as this was believed to reduce the risk of disc reherniation and progressive instabil...

journal_title：BMC musculoskeletal disorders

authors： Daly CD,Lim KZ,Lewis J,Saber K,Molla M,Bar-Zeev N,Goldschlager T

更新日期：2017-07-20 00:00:00

abstract：BACKGROUND:Open dislocations are infrequent, often associated with damage to the neuro vascular structures. We present an unusual case of an open antero-lateral dislocation of the elbow, which was not associated with any vascular or neural injury. CASE PRESENTATION:A 34 year female dance instructor sustained an open d...

journal_title：BMC musculoskeletal disorders

authors： Alonso JA,Roy BR,Shaw DL

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Whether the increase in vascular disease prevalence and mortality in OA populations is a result of co-occurrence of cardiovascular disease and OA, which are both common in the older population, is due to OA treatments or to the common association with reduced physical activity and/or obesity is unclear. One ...

journal_title：BMC musculoskeletal disorders

authors： Davies-Tuck ML,Kawasaki R,Wluka AE,Wong TY,Hodgson L,English DR,Giles GG,Cicuttini F

更新日期：2012-12-20 00:00:00

abstract：BACKGROUND:Overall performance, particularly in a very popular sports activity such as running, is typically influenced by the status of the musculoskeletal system and the level of training and conditioning of the biological structures. Any change in the musculoskeletal system's biomechanics, especially in the feet and...

journal_title：BMC musculoskeletal disorders

authors： Matias AB,Taddei UT,Duarte M,Sacco IC

更新日期：2016-04-14 00:00:00

abstract：BACKGROUND:Destructive spondyloarthropathy (DSA) is one of the major complications in patients undergoing long-term hemodialysis. To the best of our knowledge, an epidural abscess occurring at the level of preexisting cervical DSA has not been well described in the literature. We report a unique case of quadriplegia ca...

journal_title：BMC musculoskeletal disorders

authors： Lee JS,Ryu JH,Park JT,Kim KW

更新日期：2017-01-10 00:00:00

abstract：BACKGROUND:Social media is increasingly used by patients to source information for managing chronic disease. The aim of this study was to understand patient information needs about gout by a content analysis of questions posted on the social news website Reddit. METHODS:We analysed questions posted onto the 'Gout suff...

journal_title：BMC musculoskeletal disorders

authors： Derksen C,Serlachius A,Petrie KJ,Dalbeth N

更新日期：2017-11-23 00:00:00

abstract：BACKGROUND:Vertebroplasty with posterior spinal fusion (VP + PSF) is one of the most widely accepted surgical techniques for treating osteoporotic vertebral collapse (OVC). Nevertheless, the effect of the extent of fusion on surgical outcomes remains to be established. This study aimed to evaluate the surgical outcomes...

journal_title：BMC musculoskeletal disorders

authors： Ishikawa Y,Watanabe K,Katsumi K,Ohashi M,Shibuya Y,Izumi T,Hirano T,Endo N,Kaito T,Yamashita T,Fujiwara H,Nagamoto Y,Matsuoka Y,Suzuki H,Nishimura H,Terai H,Tamai K,Tagami A,Yamada S,Adachi S,Yoshii T,Ushio S,

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Anterior cruciate ligament (ACL) tears are common, functionally disabling, and predispose to subsequent injuries and early onset of osteoarthritis in the knee. Injuries result in muscular atrophy and impaired muscular activation. To optimize surgical methods and rehabilitation strategies, knowledge of the ef...

journal_title：BMC musculoskeletal disorders

authors： Strandberg S,Lindström M,Wretling ML,Aspelin P,Shalabi A

更新日期：2013-04-29 00:00:00

abstract：BACKGROUND:It is known that there are large regional variations in treatment methods for the management of proximal humeral fractures. The objective of this study was to investigate the national surgical trends in elderly patients with proximal humeral fractures in South Korea. METHODS:We analyzed the Korean Health In...

journal_title：BMC musculoskeletal disorders

authors： Jo YH,Lee KH,Lee BG

更新日期：2019-03-30 00:00:00

abstract：BACKGROUND:Impaired lumbo-pelvic movement in people with low back pain during bending task has been reported previously. However, the regional mobility and the pattern of the lumbo-pelvic movement were found to vary across studies. The inconsistency of the findings may partly be related to variations in the speed at wh...

journal_title：BMC musculoskeletal disorders

authors： Tsang SMH,Szeto GPY,Li LMK,Wong DCM,Yip MMP,Lee RYW

更新日期：2017-04-17 00:00:00

abstract：BACKGROUND:Health-related quality of life (HRQoL) is defined as the patient's perception of their health status. HRQoL can be modified by illnesses, treatments or social and health policies. Chronic musculoskeletal pain is a modifying factor of HRQoL that leads to lower quality of life, elevated suffering and disabilit...

journal_title：BMC musculoskeletal disorders

authors： Mena-Iturriaga MJ,Mauri-Stecca MV,Sizer PS,Leppe J

更新日期：2020-04-21 00:00:00

abstract：BACKGROUND:Leg pain associated with low back pain (LBP) is recognized as a risk factor for a poor prognosis, and is included as a component in most LBP classification systems. The location of leg pain relative to the knee and the presence of a positive straight leg raise test have been suggested to have clinical implic...

journal_title：BMC musculoskeletal disorders

authors： Kongsted A,Kent P,Albert H,Jensen TS,Manniche C

更新日期：2012-11-28 00:00:00

abstract：BACKGROUND:The erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are two commonly used measures of inflammation in rheumatoid arthritis (RA). As current RA treatment guidelines strongly emphasize early and aggressive treatment aiming at fast remission, optimal measurement of inflammation becomes increas...

journal_title：BMC musculoskeletal disorders

authors： Siemons L,Ten Klooster PM,Vonkeman HE,van Riel PL,Glas CA,van de Laar MA

更新日期：2014-11-06 00:00:00

abstract：BACKGROUND:Low-Dye taping is used for excessive pronation at the subtalar joint of the foot. Previous research has focused on the tape's immediate effect on plantar pressure. Its effectiveness following exercise has not been investigated. Peak plantar pressure distribution provides an indirect representation of subtala...

journal_title：BMC musculoskeletal disorders

authors： Nolan D,Kennedy N

更新日期：2009-04-21 00:00:00