Lumbar microdiscectomy and post-operative activity restrictions: a protocol for a single blinded randomised controlled trial.

Abstract:

BACKGROUND:Lumbar microdiscectomy is the most commonly performed spinal surgery procedure, with over 300,000 cases performed annually in the United States alone. Traditionally, patients were advised to restrict post-operative activity as this was believed to reduce the risk of disc reherniation and progressive instability. However, this practice would often delay patients return to work. In contemporary practice many surgeons do not restrict patient post-operative activity due to the perception this practice is unnecessary. We describe a randomised controlled trial to assess the impact of activity restrictions on clinical outcome following lumbar discectomy. METHODS/DESIGN:The lumbar microdiscectomy and post-operative activity restriction trial is a multi-centre, randomised, controlled single blinded trial. Two hundred ten patients due to undergo single level lumbar microdiscectomy without a history of previous spine surgery, infection or fracture are randomised to be advised either restricted or unrestricted activity for a period of 30 days following lumbar microdiscectomy. Actual adherence with trial allocation will be monitored bioelectronically via a wearable device. Outcome assessment at follow up will occur at 1, 3, 6 and 12 months. The primary outcome will be a composite endpoint comprising changes in Visual Analogue Scale (Leg and Back), Oswestry Disability Index and the absence of intervertebral disc reherniation or secondary intervention. DISCUSSION:This randomised controlled trial will directly compare post-operative protocols of activity restrictions and no restrictions following lumbar discectomy with adherence monitored bioelectronically. TRIAL REGISTRATION:Australian New Zealand Clinical Trials Registry: ACTRN12616001360404 (retrospectively registered 30/09/2016).

authors

Daly CD,Lim KZ,Lewis J,Saber K,Molla M,Bar-Zeev N,Goldschlager T

doi

10.1186/s12891-017-1681-3

subject

Has Abstract

pub_date

2017-07-20 00:00:00

pages

312

issue

1

issn

1471-2474

pii

10.1186/s12891-017-1681-3

journal_volume

18

pub_type

杂志文章,多中心研究,随机对照试验
  • Patellar sleeve avulsion fracture in a patient with Sinding-Larsen-Johansson syndrome: a case report.

    abstract:BACKGROUND:Patellar sleeve avulsion (PSA) fractures are rare injuries that occur in in skeletally immature patients. Initial diagnosis is key to a successful outcome, as these injuries are easily overlooked on plain radiographs with poor results well documented from delayed management. High index of suspicion from the ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-020-03297-z

    authors: Schmidt-Hebbel A,Eggers F,Schütte V,Achtnich A,Imhoff AB

    更新日期:2020-04-23 00:00:00

  • Effects of low-dye taping on plantar pressure pre and post exercise: an exploratory study.

    abstract:BACKGROUND:Low-Dye taping is used for excessive pronation at the subtalar joint of the foot. Previous research has focused on the tape's immediate effect on plantar pressure. Its effectiveness following exercise has not been investigated. Peak plantar pressure distribution provides an indirect representation of subtala...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-10-40

    authors: Nolan D,Kennedy N

    更新日期:2009-04-21 00:00:00

  • Six-week high-intensity exercise program for middle-aged patients with knee osteoarthritis: a randomized controlled trial [ISRCTN20244858].

    abstract:BACKGROUND:Studies on exercise in knee osteoarthritis (OA) have focused on elderly subjects. Subjects in this study were middle-aged with symptomatic and definite radiographic knee osteoarthritis. The aim was to test the effects of a short-term, high-intensity exercise program on self-reported pain, function and qualit...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2474-6-27

    authors: Thorstensson CA,Roos EM,Petersson IF,Ekdahl C

    更新日期:2005-05-30 00:00:00

  • Meat consumption and risk of primary hip and knee joint replacement due to osteoarthritis: a prospective cohort study.

    abstract:BACKGROUND:There is emerging evidence for a beneficial effect of meat consumption on the musculoskeletal system. However, whether it affects the risk of knee and hip osteoarthritis is unknown. We performed a prospective cohort study to examine the relationship between meat consumption and risk of primary hip and knee r...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-12-17

    authors: Wang Y,Simpson JA,Wluka AE,English DR,Giles GG,Graves S,Cicuttini FM

    更新日期:2011-01-16 00:00:00

  • A prospective cohort study identifying risk factors for shoulder injuries in adolescent elite handball players: the Karolinska Handball Study (KHAST) study protocol.

    abstract:BACKGROUND:Handball is a physical contact sport that includes frequent overhead throwing, and this combination leads to a high rate of shoulder injuries. Several factors have been associated with shoulder injuries in overhead athletes, but strong scientific evidence is lacking for most suggested risk factors. We theref...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-017-1852-2

    authors: Asker M,Waldén M,Källberg H,Holm LW,Skillgate E

    更新日期:2017-11-22 00:00:00

  • Postural changes in women with chronic pelvic pain: a case control study.

    abstract:BACKGROUND:Chronic pelvic pain (CPP) is a lower abdominal pain lasting at least 6 months, occurring continuously or intermittently and not associated exclusively with menstruation or intercourse. Although the musculoskeletal system has been found to be involved in CPP, few studies have assessed the contribution of post...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-10-82

    authors: Montenegro ML,Mateus-Vasconcelos EC,Rosa E Silva JC,Dos Reis FJ,Nogueira AA,Poli-Neto OB

    更新日期:2009-07-07 00:00:00

  • Effectiveness and cost-effectiveness of rehabilitation after lumbar disc surgery (REALISE): design of a randomised controlled trial.

    abstract:BACKGROUND:Patients who undergo lumbar disc surgery for herniated discs, are advocated two different postoperative management strategies: a watchful waiting policy, or referral for rehabilitation immediately after discharge from the hospital. A direct comparison of the effectiveness and cost-effectiveness of these two ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1186/1471-2474-14-124

    authors: Oosterhuis T,van Tulder M,Peul W,Bosmans J,Vleggeert-Lankamp C,Smakman L,Arts M,Ostelo R

    更新日期:2013-04-05 00:00:00

  • Validation of the Mayo Hip Score: construct validity, reliability and responsiveness to change.

    abstract:BACKGROUND:Previous studies have provided the initial evidence for construct validity and test-retest reliability of the Mayo Hip Score. Instruments used for Total Hip Arthroplasty (THA) outcomes assessment should be valid, reliable and responsive to change. Our main objective was to examine the responsiveness to chang...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-016-0868-3

    authors: Singh JA,Schleck C,Harmsen WS,Lewallen DG

    更新日期:2016-01-19 00:00:00

  • Increasing comorbidity is associated with worsening physical function and pain after primary total knee arthroplasty.

    abstract:BACKGROUND:Previous studies suggested that pre-operative comorbidity was a risk factor for worse outcomes after TKA. To our knowledge, studies have not examined whether postoperative changes in comorbidity impact pain and function outcomes longitudinally. Our objective was to examine if increasing comorbidity postopera...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-016-1261-y

    authors: Hilton ME,Gioe T,Noorbaloochi S,Singh JA

    更新日期:2016-10-07 00:00:00

  • Relationship between time-integrated disease activity estimated by DAS28-CRP and radiographic progression of anatomical damage in patients with early rheumatoid arthritis.

    abstract:BACKGROUND:The main aim of the study was to investigate the relationship between persistent disease activity and radiographic progression of joint damage in early rheumatoid arthritis (ERA). METHODS:Forty-eight patients with active ERA was assessed every 3 months for disease activity for 3 years. Radiographic damage w...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-12-120

    authors: Salaffi F,Carotti M,Ciapetti A,Gasparini S,Filippucci E,Grassi W

    更新日期:2011-05-30 00:00:00

  • Work-life conflict and musculoskeletal disorders: a cross-sectional study of an unexplored association.

    abstract:BACKGROUND:The health consequences of work-family or rather work-life conflict (WLC) have been studied by numerous researchers. The work-related causes of musculoskeletal disorders (MSD) are also well explored. And stress (at work) has been found to be a consequence of WLC as well as a cause of MSD. But very little is ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-12-60

    authors: Hämmig O,Knecht M,Läubli T,Bauer GF

    更新日期:2011-03-16 00:00:00

  • Minimal important improvement thresholds for the six-minute walk test in a knee arthroplasty cohort: triangulation of anchor- and distribution-based methods.

    abstract:BACKGROUND:The 6-minute walk test (6MWT) is a commonly used metric for measuring change in mobility after knee arthroplasty, however, what is considered an improvement after surgery has not been defined. The determination of important change in an outcome assessment tool is controversial and may require more than one a...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12891-016-1249-7

    authors: Naylor JM,Mills K,Buhagiar M,Fortunato R,Wright R

    更新日期:2016-09-13 00:00:00

  • Anti-infliximab antibodies are already detectable in most patients with rheumatoid arthritis halfway through an infusion cycle: an open-label pharmacokinetic cohort study.

    abstract:BACKGROUND:This study in patients with rheumatoid arthritis (RA) treated with infliximab describes prospectively the course of (anti)infliximab levels within an infusion cycle to assess at what moment patients develop low/no infliximab trough levels and/or detectable anti-infliximab levels. METHODS:Infliximab treated ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 临床试验,杂志文章

    doi:10.1186/1471-2474-12-12

    authors: van den Bemt BJ,den Broeder AA,Wolbink GJ,Hekster YA,van Riel PL,Benraad B,van den Hoogen FH

    更新日期:2011-01-13 00:00:00

  • Gel-type autologous chondrocyte (Chondron) implantation for treatment of articular cartilage defects of the knee.

    abstract:BACKGROUND:Gel-type autologous chondrocyte (Chondron) implantations have been used for several years without using periosteum or membrane. This study involves evaluations of the clinical results of Chondron at many clinical centers at various time points during the postoperative patient follow-up. METHODS:Data from 98...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-11-103

    authors: Choi NY,Kim BW,Yeo WJ,Kim HB,Suh DS,Kim JS,Kim YS,Seo YH,Cho JY,Chun CW,Park HS,Shetty AA,Kim SJ

    更新日期:2010-05-28 00:00:00

  • Injuries in professional male football players in Kosovo: a descriptive epidemiological study.

    abstract:BACKGROUND:The incidence and severity of football-related injuries has been found to differ strongly between professional leagues from different countries. The aims of this study were to record the incidence, type and severity of injuries in Kosovarian football players and investigate the relationship between injury in...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-016-1202-9

    authors: Shalaj I,Tishukaj F,Bachl N,Tschan H,Wessner B,Csapo R

    更新日期:2016-08-12 00:00:00

  • Consumption of medical resources and outcome of shoulder disorders in primary health care consulters.

    abstract:BACKGROUND:Shoulder disorders are common problems in primary health care. The course of disease of patients consulting for a new episode of a shoulder problem has been thought to be benign. In this prospective cohort study, we assessed the one-year consumption of medical resources and clinical outcome of shoulder disor...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-14-348

    authors: Paloneva J,Koskela S,Kautiainen H,Vanhala M,Kiviranta I

    更新日期:2013-12-13 00:00:00

  • Does the use of a closed-suction drain reduce the effectiveness of an antibiotic-loaded spacer in two-stage exchange Arthroplasty for Periprosthetic hip infection? A prospective, randomized, controlled study.

    abstract:BACKGROUND:There is a concern regarding the use of a closed-suction drain (CSD) in two-stage exchange arthroplasty for periprosthetic joint infection as it may decrease the antibiotic concentrations in the joint fluids. The purpose of this study was to identify whether the use of a CSD could reduce local antibiotic con...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12891-019-2974-5

    authors: Xu C,Jia CQ,Kuo FC,Chai W,Zhang MH,Chen JY

    更新日期:2019-12-04 00:00:00

  • Effect of preoperative vitamin D deficiency on functional outcomes after high tibial osteotomy: a retrospective case control study.

    abstract:BACKGROUND:This study aimed to evaluate the effects of vitamin D deficiency on the functional outcomes following a high tibial osteotomy (HTO). METHODS:Clinical data of 209 patients (327 knees) who underwent HTO done by a single surgeon were retrospectively registered for the study. Ninety-four patients (94 knees) who...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-020-03295-1

    authors: Choi W,Kim JH,Byun SE,Ryu HS,Rojas D

    更新日期:2020-04-17 00:00:00

  • INvestigational Vertebroplasty Efficacy and Safety Trial (INVEST): a randomized controlled trial of percutaneous vertebroplasty.

    abstract:BACKGROUND:The treatment of painful osteoporotic vertebral compression fractures has historically been limited to several weeks of bed rest, anti-inflammatory and analgesic medications, calcitonin injections, or external bracing. Percutaneous vertebroplasty (the injection of bone cement into the fractured vertebral bod...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1186/1471-2474-8-126

    authors: Gray LA,Jarvik JG,Heagerty PJ,Hollingworth W,Stout L,Comstock BA,Turner JA,Kallmes DF

    更新日期:2007-12-20 00:00:00

  • Differences in Achilles tendon stiffness in people with gout: a pilot study.

    abstract:BACKGROUND:Gout has been associated with weaker foot/leg muscles and altered gait patterns. There is also evidence of on-going foot pain and an increased risk of tendinopathy, with the Achilles and patella tendons most frequently affected in gout. Additionally, the inflammation associated with gout may change tissue el...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-020-03598-3

    authors: Otter S,Payne C,Jones AM,Webborn N,Watt P

    更新日期:2020-10-07 00:00:00

  • Non-fusion procedure using PEEK rod systems for lumbar degenerative diseases: clinical experience with a 2-year follow-up.

    abstract:BACKGROUND:Polyetheretherketone (PEEK) rod system is a novel pedicle-based dynamic stabilization system. This study evaluated clinical and radiographic outcomes of non-fusion surgery by PEEK rod systems for treatment of degenerative lumbar diseases with a 2-year follow-up. METHODS:From February 2012 to October 2012, 3...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-016-0913-2

    authors: Huang W,Chang Z,Song R,Zhou K,Yu X

    更新日期:2016-02-01 00:00:00

  • Effects of short- and long-term glucocorticoid-induced osteoporosis on plasma metabolome and lipidome of ovariectomized sheep.

    abstract:BACKGROUND:Understanding the metabolic and lipidomic changes that accompany bone loss in osteoporosis might provide insights about the mechanisms behind molecular changes and facilitate developing new drugs or nutritional strategies for osteoporosis prevention. This study aimed to examine the effects of short- or long-...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-020-03362-7

    authors: Cabrera D,Kruger M,Wolber FM,Roy NC,Fraser K

    更新日期:2020-06-05 00:00:00

  • Topical co-administration of zoledronate with recombinant human bone morphogenetic protein-2 can induce and maintain bone formation in the bone marrow environment.

    abstract:BACKGROUND:Bone morphogenetic proteins (BMPs) induce osteogenesis in various environments. However, when BMPs are used alone in the bone marrow environment, the maintenance of new bone formation is difficult owing to vigorous bone resorption. This is because BMPs stimulate the differentiation of not only osteoblast pre...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-021-03971-w

    authors: Ueyama H,Ohta Y,Imai Y,Suzuki A,Sugama R,Minoda Y,Takaoka K,Nakamura H

    更新日期:2021-01-20 00:00:00

  • Lentivirus-mediated short hairpin RNA interference targeting TNF-alpha in macrophages inhibits particle-induced inflammation and osteolysis in vitro and in vivo.

    abstract:BACKGROUND:Aseptic loosening is a significant impediment to joint implant longevity. Prosthetic wear particles are postulated to play a central role in the onset and progression of periprosthetic osteolysis, leading to aseptic loosening of the prosthesis. METHODS:We investigated the inhibitory effects of a lentivirus-...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-016-1290-6

    authors: Qin CQ,Huang DS,Zhang C,Song B,Huang JB,Ding Y

    更新日期:2016-10-18 00:00:00

  • An exploratory study investigating the effect of foot type and foot orthoses on gluteus medius muscle activity.

    abstract:BACKGROUND:Abnormal gluteus medius muscle activity is associated with a number of musculoskeletal conditions. Research investigating the effect of foot type and foot orthoses on gluteus medius muscle activity is both conflicting and limited. The primary aim was to investigate the relationship between foot type and glut...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-020-03683-7

    authors: Sadler S,Spink M,de Jonge XJ,Chuter V

    更新日期:2020-10-07 00:00:00

  • Kinematic characteristics of lumbar spinous processes during axial rotation in patients with lumbar degenerative disc disease lateral lumbar interbody fusion and intervention.

    abstract:BACKGROUND:Data about minimally invasive surgery for the treatment of patients with degenerative disc disease (DDD) has been reported. However, no quantitative knowledge about the biomechanical characteristics of the spinous processes in patients with DDD after operation was reported in the literature. METHODS:Fourtee...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-017-1504-6

    authors: Zhang B,Huang W,Xia H,Feng X

    更新日期:2017-04-04 00:00:00

  • Patients' experiences of living with and receiving treatment for fibromyalgia syndrome: a qualitative study.

    abstract:BACKGROUND:Fibromyalgia syndrome (FMS) presents a challenge for patients and health care staff across many medical specialities. The aetiology is multi-dimensional, involving somatic, psychological and social factors. Patients' views were obtained to understand their experience of living with this long-term condition, ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2474-10-124

    authors: Lempp HK,Hatch SL,Carville SF,Choy EH

    更新日期:2009-10-07 00:00:00

  • The predictive factors that are associated with the number of sutures used during meniscal repair.

    abstract:PURPOSE:To investigate factors associated with the consumption of a large number of sutures during arthroscopic meniscus repair procedures. METHODS:All patients who received meniscal repair, with or without concomitant anterior cruciate ligament (ACL) reconstruction, in our hospital from January 2015 to December 2019 ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-020-03911-0

    authors: Song X,Chen D,Qi X,Jiang Q,Xia C

    更新日期:2021-01-12 00:00:00

  • High detection rate of osteoporosis with screening of a general hospitalized population: a 6-year study in 6406 patients in a university hospital setting.

    abstract:BACKGROUND:Osteoporosis is a highly prevalent disease identified by Dual Energy X-ray Absorptiometry (DEXA) that can be performed in an ambulatory (out-patient) or hospitalized population. We evaluated the use of baseline in-hospital DEXA screening to identify osteoporosis in ambulatory care and hospitalized patients; ...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-020-3116-9

    authors: Malaise O,Detroz M,Leroy M,Leonori L,Seidel L,Malaise MG

    更新日期:2020-02-10 00:00:00

  • Psychometric evaluation of spinal assessment methods to screen for scoliosis in children and adolescents with cerebral palsy.

    abstract:BACKGROUND:In cerebral palsy (CP) there is an increased risk of scoliosis. It is important to identify a progressive scoliosis early-on because the results of surgery depend on the magnitude of the curve. The Swedish follow-up program for cerebral palsy (CPUP) includes clinical examinations of the spine. The reliabilit...

    journal_title:BMC musculoskeletal disorders

    pub_type: 杂志文章

    doi:10.1186/s12891-015-0801-1

    authors: Persson-Bunke M,Czuba T,Hägglund G,Rodby-Bousquet E

    更新日期:2015-11-14 00:00:00