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High detection rate of osteoporosis with screening of a general hospitalized population: a 6-year study in 6406 patients in a university hospital setting.

Abstract：

BACKGROUND:Osteoporosis is a highly prevalent disease identified by Dual Energy X-ray Absorptiometry (DEXA) that can be performed in an ambulatory (out-patient) or hospitalized population. We evaluated the use of baseline in-hospital DEXA screening to identify osteoporosis in ambulatory care and hospitalized patients; we also assessed specific risk factors for osteoporosis among these populations. METHODS:We included a baseline initial DEXA from 6406 consecutive patients at our tertiary referral University Hospital. RESULTS:Osteoporosis was diagnosed in 22.3% of the study population. In univariate analysis, osteoporosis risk factors were age, fracture history and low BMI (for all 3 sites), but also corticotherapy (lumbar spine and femoral neck) and male (lumbar spine). In multivariate analysis, age, fracture history, low BMI, and male increased osteoporosis risk. In-hospital screening yielded a higher percentage of osteoporosis positive scans than ambulatory care screening (31.8% vs 18.5%, p < 0.001). In-hospital screening targeted an older and more predominantly male population with a higher fracture history. Z-scores revealed that this difference was not only due to an older age of the population and mainly concerned cortical bone. CONCLUSIONS:In-hospital osteoporosis screening revealed more osteoporosis than screening in ambulatory practice and could be an additional tool to improve the identification and management of osteoporosis. In addition to typical risk factors, we identified male gender as associated with osteoporosis detection in our cohort.

journal_name

BMC Musculoskelet Disord

journal_title

BMC musculoskeletal disorders

authors

Malaise O,Detroz M,Leroy M,Leonori L,Seidel L,Malaise MG

doi

10.1186/s12891-020-3116-9

subject

Has Abstract

pub_date

2020-02-10 00:00:00

pages

90

issue

1

issn

1471-2474

pii

10.1186/s12891-020-3116-9

journal_volume

21

pub_type

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