Abstract:
BACKGROUND:Albumin is an important protein that transports hormones, fatty acids, and exogenous drugs; it also maintains plasma oncotic pressure. Albumin is considered a negative active phase protein because it decreases during injuries and sepsis. In spite of other factors predicting surgical outcomes, the effect of pre and postoperative serum albumin to surgical complications can be assessed by calculating the percentage decrease in albumin (delta albumin). This study aimed to explore perioperative serum albumin as a predictor of adverse outcomes in major abdominal surgeries. METHODS:All eligible adult participants from Kilimanjaro Christian Medical Centre Surgical Department were enrolled in a convenient manner. Data were collected using a study questionnaire. Full Blood Count (FBP), serum albumin levels preoperatively and on postoperative day 1 were measured in accordance with Laboratory Standard Operating Procedures (SOP). Data was entered and analyzed using STATA version 14. Association and extent of decrease in albumin levels as a predictor of surgical site infection (SSI), delayed wound healing and death within 30 days of surgery was determined using ordinal logistic regression models. In determining the diagnostic accuracy, a Non-parametric Receiver Operating Curve (ROC) model was used. We adjusted for ASA classification, which had a negative confounding effect on the predictive power of the percent drop in albumin to adverse outcomes. RESULTS:Sixty one participants were studied; the mean age was 51.6 (SD16.3), the majorities were males 40 (65.6%) and post-operative adverse outcomes were experienced by 28 (45.9%) participants. In preoperative serum albumin values, 40 (67.8%) had lower than 3.4 g/l while 51 (91%) had postoperative albumin values lower than 3.4 g/l. Only 15 (27.3%) had high delta albumin with the median percentage value of 14.77%. Delta albumin was an independent significant factor associated with adverse outcome (OR: 6.68; 95% CI: 1.59, 28.09); with a good predictive power and area under ROC curve (AUC) of 0.72 (95% CI 0.55 0.89). The best cutoff value was 11.61% with a sensitivity of 76.92% and specificity of 51.72%. CONCLUSION:Early perioperative decreases in serum albumin levels may be a good, simple and cost effective tool to predict adverse outcomes in major abdominal surgeries.
journal_name
BMC Surgjournal_title
BMC surgeryauthors
Issangya CE,Msuya D,Chilonga K,Herman A,Shao E,Shirima F,Naman E,Mkumbi H,Pyuza J,Mtui E,Sanga LA,Abdul S,Leyaro BJ,Chugulu Sdoi
10.1186/s12893-020-00820-wsubject
Has Abstractpub_date
2020-07-14 00:00:00pages
155issue
1issn
1471-2482pii
10.1186/s12893-020-00820-wjournal_volume
20pub_type
杂志文章相关文献
BMC Surgery文献大全abstract:BACKGROUND:Kimura's disease is a rare, benign chronic inflammatory disease of unknown etiology that mostly affects Asians. The disease typically presents as subcutaneous masses in the head or neck region that are predominantly found in the preauricular and submandibular areas. CASE PRESENTATION:A 7-year-old boy presen...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-00870-0
更新日期:2020-09-21 00:00:00
abstract:BACKGROUND:Acupuncture is a famous traditional medicine in China, but the complications caused by broken acupuncture needles have been rarely reported. It seems easy to remove the foreign matters usually, but things become difficulty in special issues. Here, we reported a recently encountered case to provide an importa...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-019-0572-y
更新日期:2019-08-06 00:00:00
abstract:BACKGROUND:Increases in the levels of serum C-reactive protein (CRP) and creatinine (Cr) and decreases in those of albumin (Alb) are commonly observed in acute pancreatitis (AP). We aimed to evaluate the efficacy of the Cr/Alb and CRP/Alb ratios in the prediction of surgical treatment effect in AP patients. METHODS:Th...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-00991-6
更新日期:2020-12-09 00:00:00
abstract:BACKGROUND:Myelolipoma is a rare neoplasm composed of yellowish adipose tissue and reddish-brown tissue corresponding to hematopoietic or hemorrhages. It typically occurs in adrenal glands as a solitary, well-circumscribed mass, and the thoracic location is extremely unusual. CASE PRESENTATION:We present a rare case w...
journal_title:BMC surgery
pub_type: 杂志文章,评审
doi:10.1186/1471-2482-14-42
更新日期:2014-07-09 00:00:00
abstract:BACKGROUND:Infected nonunion of the humeral diaphysis is a challenging problem for orthopedic surgeons. This study aimed to evaluate the outcome of using a locking compression plate (LCP) as a definitive external fixator in the management of infected nonunion of the humeral diaphysis after failure of internal fixation....
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-016-0167-9
更新日期:2016-08-05 00:00:00
abstract:BACKGROUND:Bezoars are collections of indigestible material in the gastrointestinal tract, mostly described in children. Polyurethane "plastobezoars" consisting of composites used in the construction industry are rarely described bezoars formed in the esophagus and stomach, causing gastrointestinal obstruction, usually...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-00945-y
更新日期:2020-11-12 00:00:00
abstract:BACKGROUND:Endovascular aneurysm repair (EVAR) has been a revolutionary development in the treatment of abdominal aortic aneurysms (AAAs). Meanwhile, unfavorable anatomy of the aneurysm has always been a challenge to vascular surgeons, and the application of EVAR in emergent and elderly patients are still in dispute. ...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-14-11
更新日期:2014-03-05 00:00:00
abstract:BACKGROUND:We present a series of patients with blunt abdominal trauma who underwent damage control laparotomy (DCL) and introduce a nomogram that we created to predict survival among these patients. METHODS:This was a retrospective study. From January 2002 to June 2012, 91 patients underwent DCL for hemorrhagic shock...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-14-24
更新日期:2014-04-28 00:00:00
abstract:BACKGROUND:A standard of care for the treatment of small renal masses is partial nephrectomy. The open and laparoscopic approaches have been well described in the literature. Robotic assistance may augment partial nephrectomy by aiding in dissection and renal reconstruction. In this communication we describe the surgic...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-8-16
更新日期:2008-09-24 00:00:00
abstract:BACKGROUND:To compare the clinical efficacy of single posterior debridement, bone grafting and instrumentation with that of single-stage anterior debridement, bone grafting and posterior instrumentation for treatment of adult patients with thoracic and thoracolumbar spinal tuberculosis (TB). METHODS:We performed a ret...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-018-0405-4
更新日期:2018-09-03 00:00:00
abstract:BACKGROUND:Laparoscopy induces adhesion due to ischemia-reperfusion injury. However, the detail pathomechanism is poorly understood. This study aimed to investigate the impact of laparoscopy on mast cell and mesothelium morphological changes in the rat. METHODS:Forty-nine males of Sprague-Dawley Rattus norvegicus were...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-00775-y
更新日期:2020-05-24 00:00:00
abstract:BACKGROUND:Three-dimensional (3D) printing may represent a useful tool to provide, in surgery, a good representation of surgical scenario before surgery, particularly in complex cases. Recently, such a technology has been utilized to plan operative interventions in spinal, neuronal, and cardiac surgeries, but few data ...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-019-0621-6
更新日期:2019-10-25 00:00:00
abstract:BACKGROUND:Herein we present our experience with laparoscopic common bile duct exploration (LCBDE) in managing common bile duct stones. METHODS:Data of 129 consecutive patients who underwent laparoscopic cholecystectomy (LC) and LCBDE done at our institutes from April 2011 through June 2016 were prospectively recorded...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-017-0225-y
更新日期:2017-03-31 00:00:00
abstract:BACKGROUND:Necrotising Fasciitis is a life threatening soft tissue infection which requires aggressive, early surgical management. CASE PRESENTATION:We present a rare case of a retroperitoneal perforation of a carcinoma of the caecum presenting as a necrotising fasciitis of the anterior abdominal wall. CONCLUSION:Thi...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-6-11
更新日期:2006-09-29 00:00:00
abstract:BACKGROUND:This study aimed to explore mid-term clinical results of cementless total hip arthroplasty (THA) with modified trochanteric osteotomy in Crowe type IV developmental dysplasia of the hip (DDH). METHODS:Thirteen patients (13 hips) with Crowe type IV DDH who underwent THA with modified trochanteric osteotomy b...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-01002-4
更新日期:2021-01-06 00:00:00
abstract:BACKGROUND:Bleeding and rupture of blood vessels has been correlated with weather conditions in the past. This is the first study in the world literature with the aim of investigating the relationship between atmospheric pressure and temperature with the presentation of aortic dissection. METHODS:The dates of all emer...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-5-21
更新日期:2005-10-15 00:00:00
abstract:BACKGROUND:Fecal incontinence is a common and severely disabling disorder. For patients with severe fecal incontinence, surgery may prove to be the only adequate treatment option. METHODS:This study reports on 43 patients that were treated with a prosthetic sphincter system between 2005 and 2009 in three coloproctolog...
journal_title:BMC surgery
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2482-13-45
更新日期:2013-10-08 00:00:00
abstract:BACKGROUND:Immediate laparoscopic cholecystectomy is the accepted standard for the treatment of acute cholecystitis. The aim of the present study was to evaluate the feasibility of a standardized approach with tailored care maps for pre- and postoperative care by comparing pain, nausea and patient satisfaction after el...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-016-0194-6
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Suspected acute appendicitis is the most frequent cause for emergency operations in visceral surgery worldwide. In approximately twenty percent of all cases however, the diagnosis is incorrect and patients undergo surgery without having acute appendicitis. Operations of bland appendices put patients at risk ...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-2-2
更新日期:2002-04-10 00:00:00
abstract:BACKGROUND:Mucinous cyst neoplasm of the liver (MCN-L) comprise less than 5% of all cystic liver lesions and is characterized by the presence of ovarian stroma and absence of bile duct communication. CASE PRESENTATION:Here, we discuss a 45-year-old woman who presented with symptomatic liver mass. Diagnostic workup det...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-01003-3
更新日期:2020-12-11 00:00:00
abstract:BACKGROUND:Surgical bleeding can be associated with an increased risk of morbidity and mortality across all surgical areas. Thus, numerous products have been developed to achieve haemostasis. A flowable haemostatic matrix such as Floseal® can quickly and reliably stop bleeding across the full spectrum of bleeding scena...
journal_title:BMC surgery
pub_type: 杂志文章,评审
doi:10.1186/1471-2482-14-111
更新日期:2014-12-20 00:00:00
abstract:BACKGROUND:Overall cancer incidence rates decreased in the most recent time period in both men and women, largely due to improvements in surgical therapeutic approaches (tertiary prevention) and screening programs (secondary prevention), but differences in cancer incidence and survival according to socioeconomic status...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-13-S2-S17
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:One of the potential benefits of surgical audit is improved hospital cost-efficiencies arising from lower resource consumption associated with fewer adverse events. The aim of this study was to estimate the potential cost-savings for Australian hospitals from improved surgical performance for colorectal surg...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-10-4
更新日期:2010-01-27 00:00:00
abstract:BACKGROUND:The aim of this study was to compared laparoscopic (LWR) and open wedge resection (OWR) for the treatment of gastric gastrointestinal stromal tumors (GISTs). METHODS:The data of 156 consecutive GISTs patients underwent LWR or OWR between January 2006 and December 2013 were collected retrospectively. The sur...
journal_title:BMC surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12893-015-0040-2
更新日期:2015-05-09 00:00:00
abstract:BACKGROUND:The National Comprehensive Cancer Network (NCCN) and the American Society of Clinical Oncology (ASCO) provide guidelines regarding axillary nodal evaluation in ductal carcinoma in situ (DCIS), but data regarding national compliance with these guidelines remains incomplete. METHODS:We conducted a retrospecti...
journal_title:BMC surgery
pub_type: 杂志文章,多中心研究
doi:10.1186/s12893-017-0210-5
更新日期:2017-02-07 00:00:00
abstract:BACKGROUND:Obesity is a growing public health concern in most western countries. More and more patients with high body mass index (BMI) are undergoing surgical procedures of all kinds and, in this context, obese patients are undergoing thyroid surgery more than ever before. The aim of the present study was to evaluate ...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-00939-w
更新日期:2020-11-07 00:00:00
abstract:BACKGROUND:Complete pathological response occurs in 10-20% of patients with rectal cancer who are treated with neoadjuvant chemoradiation therapy prior to pelvic surgery. The possibility that complete pathological response of rectal cancer can also occur with neoadjuvant chemotherapy alone (without radiation) is an int...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-14-4
更新日期:2014-01-17 00:00:00
abstract:BACKGROUND:In the treatment of spinal cord tumors, complete tumor resection with complete reconstruction of the spine represents the ideal goal. However, for the treatment of heavily calcified spinal meningioma, en-bloc resection of the tumor together with the involved dura at the tumor base through laminectomy is quit...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-015-0066-5
更新日期:2015-07-04 00:00:00
abstract:BACKGROUND:This study investigated perioperative clinical risk factors for early post-transplant bacteremia in patients undergoing living donor liver transplantation (LDLT). Additionally, postoperative outcomes were compared between patients with and without early post-transplant bacteremia. METHODS:Clinical data of 6...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-019-0658-6
更新日期:2020-03-12 00:00:00
abstract:BACKGROUND:Primary amyloidosis of the breast is an unusual benign disease that mostly occurs in postmenopausal elderly women. Amyloidosis is the deposition of amorphous protein within tissues. Breast biopsy is necessary to make a definite diagnosis in order to avoid unnecessary surgical methods. Localized primary amylo...
journal_title:BMC surgery
pub_type: 杂志文章,评审
doi:10.1186/s12893-016-0178-6
更新日期:2016-09-13 00:00:00