Abstract:
BACKGROUND:Overall cancer incidence rates decreased in the most recent time period in both men and women, largely due to improvements in surgical therapeutic approaches (tertiary prevention) and screening programs (secondary prevention), but differences in cancer incidence and survival according to socioeconomic status are documented worldwide. Health risk behaviors, defined as habits or practices that increase an individual's likelihood of harmful health outcomes, are thought to mediate such inequalities. DISCUSSION:Obesity has been related with increased cancer incidence and mortality due to imbalance of leptin and adiponectin which are connected to activation of PI3K, MAPK, and STAT3 pathways and decreasing insulin/insulin-like growth factor (IGF)-1 and mTOR signaling via activation of 5 AMP-activated protein kinase (AMPK), respectively. Physical activity has been associated to prevent cancer by the aforementioned obesity-related mechanisms, but also increasing level of circulating vitamin D, which has been related to lower risk of several cancers, and increasing prostaglandin F2a and reducing prostaglandin E2, which are both related with cancer prevention and promotion, respectively. A large number of different substances may induce themselves a direct cytotoxicity and mutagenic action on cells by smoking, whereas alcohol promote immune suppression, the delay of DNA repair, inhibition of the detoxification of carcinogens, the production of acetaldehyde, and the contribution to abnormal DNA methylation. The combined smoking and alcohol drinking habits have been shown to increase cancer risk by smoke action of increasing the acetaldehyde burden following alcohol consumption and alcohol action of enhancing the activation of various procarcinogens contained in tobacco smoke. CONCLUSIONS:Interventions at the social level may be done to increase awareness about cancer risks and promote changing in unhealthy behaviors.
journal_name
BMC Surgjournal_title
BMC surgeryauthors
Rametta S,Grosso G,Galvano F,Mistretta A,Marventano S,Nolfo F,Buscemi S,Gangi S,Basile F,Biondi Adoi
10.1186/1471-2482-13-S2-S17subject
Has Abstractpub_date
2013-01-01 00:00:00pages
S17issn
1471-2482pii
1471-2482-13-S2-S17journal_volume
13 Suppl 2pub_type
杂志文章相关文献
BMC Surgery文献大全abstract:BACKGROUND:There are no established standard criteria for choosing the most appropriate procedure of splenic artery dissection during laparoscopic distal pancreatectomy (LDP). The aim of this study was to evaluate the clinical benefits of individualized procedures for splenic artery dissection during LDP based on the v...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-00694-y
更新日期:2020-02-13 00:00:00
abstract:BACKGROUND:Neuralgia due to iliohypogastric nerve entrapment from sutures and mesh after inguinal hernioplasty is a rare entity in clinic. Its' awareness and management remain a clinical challenge. CASE PRESENTATION:We report a case of 54-year-old male who presented with post-operative pain after 1 month and sensory d...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-018-0391-6
更新日期:2018-08-16 00:00:00
abstract:BACKGROUND:Excisional haemorrhoidectomy is the gold standard technique in patients with III and IV degree haemorrhoidal disease (HD). However, it is associated with a significant rate of post-operative pain. The aim of our study was to evaluate the efficacy of mesoglycan in the post-operative period of patients who und...
journal_title:BMC surgery
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1186/s12893-020-00914-5
更新日期:2020-10-22 00:00:00
abstract:BACKGROUND:Inguinal hernias account for 75% of abdominal wall hernias, with a lifetime risk of 27% in men and 3% in women. Major complications are recurrence, chronic pain, and surgical site infection, but their frequency is low. Few studies have reported a calcified mesh causing neuropathy by chronic compression of th...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-015-0046-9
更新日期:2015-05-17 00:00:00
abstract:BACKGROUND:A horseshoe kidney is a congenital malformation involving the fusion of the bilateral kidneys and is often accompanied by anomalies of the ureteropelvic and vascular systems. When performing resection of colorectal cancer in a patient with horseshoe kidney, damage to the ureter or excessive renal arteries sh...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-01032-y
更新日期:2021-01-06 00:00:00
abstract:BACKGROUND:The aim of this study was to assess curative effect of hysteroscopic and laparoscopic myomectomy for type II submucous myomas between 3 and 5 cm in diameter and explore the optimal surgical indications. METHODS:A retrospective analysis was performed of those who underwent hysteroscopic or laparoscopic myome...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-016-0124-7
更新日期:2016-02-27 00:00:00
abstract:BACKGROUND:It's difficult but urgent to achieve the individualized rational medication of the warfarin, we aim to predict the individualized warfarin stable dose though the artificial intelligent Adaptive neural-fuzzy inference system (ANFIS). METHODS:Our retrospective analysis based on a clinical database, involving ...
journal_title:BMC surgery
pub_type: 杂志文章,多中心研究
doi:10.1186/s12893-018-0343-1
更新日期:2018-02-15 00:00:00
abstract:BACKGROUND:Total mesorectal excision (TME) with or without neoadjuvant concurrent chemoradiotherapy (CCRT) is the treatment for rectal cancer (RC). Recently, the use of conventional laparoscopic surgery (LS) or robotic-assisted surgery (RS) has been on a steady increase cases. However, various oncological outcomes from...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-0687-1
更新日期:2020-02-03 00:00:00
abstract:BACKGROUND:The outcomes in patients with pancreatic or ampulla tumors remain unsatisfactory, especially with invasion into the hepatic artery (HA) or the superior mesenteric artery (SMA). In this setting, pancreatectomy combined with arterial resection and reconstruction may offer the possibility of an en-block resecti...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-019-0560-2
更新日期:2019-10-10 00:00:00
abstract:BACKGROUND:Restorative proctocolectomy with ileopouch-anal anastomosis (IPAA) is the treatment of choice for intractable or complicated ulcerative colitis(UC). Elderly patients often present with acute colitis requiring emergent subtotal colectomy(SC). Frail patients are at risk of developing septic complications relat...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-12-S1-S31
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:We present a series of patients with blunt abdominal trauma who underwent damage control laparotomy (DCL) and introduce a nomogram that we created to predict survival among these patients. METHODS:This was a retrospective study. From January 2002 to June 2012, 91 patients underwent DCL for hemorrhagic shock...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-14-24
更新日期:2014-04-28 00:00:00
abstract:BACKGROUND:Incisional surgical site infection (SSI) is one of the most frequent complications that occur after colorectal surgery. Surgery for colorectal perforation carries an especially high risk of incisional SSI because fecal ascites contaminates the incision intraoperatively, and in patients who underwent stoma cr...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-015-0115-0
更新日期:2015-12-18 00:00:00
abstract:BACKGROUND:The present study aimed to compare the perioperative safety and long-term survival of patients with synchronous colorectal liver metastases undergoing sequential resection (SeR), delayed resection (DeR) and simultaneous resection (SiR). METHODS:From January 2007 to December 2016, data from patients undergoi...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-0681-7
更新日期:2020-01-17 00:00:00
abstract:BACKGROUND:Albumin is an important protein that transports hormones, fatty acids, and exogenous drugs; it also maintains plasma oncotic pressure. Albumin is considered a negative active phase protein because it decreases during injuries and sepsis. In spite of other factors predicting surgical outcomes, the effect of p...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-00820-w
更新日期:2020-07-14 00:00:00
abstract::Descending necrotizing mediastinitis is a life-threatening complication of an oropharyngeal infection that requires prompt and aggressive medical and surgical therapy. Herein, we report unusual case of man suffering of sub-acute mediastinal infection due to odontoiatric abscess which exacerbated at 3 months after its ...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-13-S2-S31
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to test the effect of different pulse frequencies and amplitudes during gastric stimulation (GS) on gastric emptying in the rat. METHODS:GS was performed in 2 groups of laparotomized rats: healthy control animals, and rats with acute diabetes. The effects of four pulse frequencies ...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-2-5
更新日期:2002-07-30 00:00:00
abstract:BACKGROUND:Official guidelines recommend palliative treatments for patients with liver metastases from gastric cancer. However, many case series reported that hepatectomy for such cases is safe and effective. This systematic review compares the overall survival between hepatectomy and palliative therapy in patients wit...
journal_title:BMC surgery
pub_type: 杂志文章,评审
doi:10.1186/s12893-017-0215-0
更新日期:2017-02-13 00:00:00
abstract:BACKGROUND:To estimate the proportion of elderly patients (>70 years) with breast cancer eligible for an Exclusive IntraOperative RadioTherapy (E-IORT) and to evaluate their local recurrence-free survival rate. METHODS:This retrospective study examining two cohorts focuses on patients over 70 years old: a multi-centri...
journal_title:BMC surgery
pub_type: 杂志文章,多中心研究
doi:10.1186/s12893-016-0191-9
更新日期:2016-11-15 00:00:00
abstract:BACKGROUND:The reported incidence of hollow viscus injuries (HVI) in blunt trauma patients is approximately 1%. The most common site of injury to the intestine in blunt abdominal trauma (BAT) is the small bowel followed by colon, with mesenteric injuries occurring three times more commonly than bowel injuries. Isolated...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-015-0108-z
更新日期:2015-10-30 00:00:00
abstract:BACKGROUND:Inguinal hernia repair has often been used as a showcase to illustrate practice variation in surgery. This study determined the degree of hospital variation in proportion of patients with an inguinal hernia undergoing operative repair and the effect of this variation on clinical outcomes. METHODS:A nationwi...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-01030-0
更新日期:2021-01-20 00:00:00
abstract:BACKGROUND:Several studies have emphasized the importance of restoring thoracic kyphosis (TK) in the setting of AIS, but very few have discussed changes in cervical spine alignment following surgery. Aim of this study was to evaluate reciprocal cervical alignment change after modification of global and regional thoraco...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-019-0471-2
更新日期:2019-01-15 00:00:00
abstract:BACKGROUND:Laparoscopic large para-oesophageal hiatal hernia (LPHH) repair using mesh reinforcement significantly reduces postoperative recurrence rates compared to conventional suture repair, especially within short follow-up times. However, the ideal strategy for repairing LPHH remains disputable because no clear gui...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-019-0607-4
更新日期:2019-10-28 00:00:00
abstract:BACKGROUND/PURPOSE:Perioperative complications cause significant pediatric morbidity and mortality in low- and lower middle -income countries. This study investigates factors associated with prolonged length of stay, 90-day readmission and in-hospital mortality among pediatric patients at Eastern Regional Hospital (ERH...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-00867-9
更新日期:2020-09-22 00:00:00
abstract:BACKGROUND:The incidence of lower extremity peripheral artery disease (LE-PAD) continues to increase and associated morbidity remains high. Despite the significant development of percutaneous revascularization strategies, over the past decade, LE-PAD still represents a unique challenge for interventional cardiologists ...
journal_title:BMC surgery
pub_type: 杂志文章,评审
doi:10.1186/1471-2482-12-S1-S13
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Rhabdomyosarcoma (RMS), a malignant neoplasm that normally differentiates to form striated muscle, is the most common type of childhood soft tissue sarcoma. However, it infrequently occurs in adults and is uncommon in the liver. We herein report a case of RMS of the liver in an adult. CASE PRESENTATION:A 73...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-00742-7
更新日期:2020-04-21 00:00:00
abstract:BACKGROUND:Bacteraemia of the donor is not considered to be contraindication of organ procurement. On the other hand, infection of solid organ transplant recipients remains to be a major cause of their morbidity and mortality. When using organs from bacteraemic donors, individual risks need to be assessed and the appro...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-019-0574-9
更新日期:2019-08-14 00:00:00
abstract:BACKGROUND:Evidence is accumulating that, similar to other ventral hernias, umbilical and epigastric hernias must be mesh repaired. The difficulties involved in mesh placement and in mesh-related complications could be the reason many small abdominal hernias are still primary closed. In laparoscopic repair, a mesh is p...
journal_title:BMC surgery
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/1471-2482-14-33
更新日期:2014-05-22 00:00:00
abstract:BACKGROUND:Patients with cirrhosis have a high incidence of abdominal wall hernias and carry an elevated perioperative morbidity and mortality. The optimal surgical management strategy as well as timing of abdominal hernia repair remains controversial. METHODS:A cohort study of 67 cirrhotic patients who underwent hern...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-015-0052-y
更新日期:2015-05-21 00:00:00
abstract:BACKGROUND:Laparoscopy induces adhesion due to ischemia-reperfusion injury. However, the detail pathomechanism is poorly understood. This study aimed to investigate the impact of laparoscopy on mast cell and mesothelium morphological changes in the rat. METHODS:Forty-nine males of Sprague-Dawley Rattus norvegicus were...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/s12893-020-00775-y
更新日期:2020-05-24 00:00:00
abstract:BACKGROUND:In view of the disturbed esophageal peristaltic activity and abnormal esophageal motility in gastroesophageal reflux disease, (GERD), we investigated the hypothesis that these changes result from a disordered myoelectric activity of the esophagus. METHODS:The electric activity of the esophagus (electroesoph...
journal_title:BMC surgery
pub_type: 杂志文章
doi:10.1186/1471-2482-4-13
更新日期:2004-10-05 00:00:00