Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) for chronic insomnia disorder ('CANSLEEP' trial): protocol for a randomised, placebo-controlled, double-blinded, proof-of-concept trial.

abstract：INTRODUCTION:The Bristol Stool Form Scale (BSS) which consists of 7 photographs of different stool forms allows assessment of stool consistency (scale 1 for hard lumps to scale 7 for watery stools), in an objective manner in adults. The BSS is also sometimes used to characterise the stools of infants and young children...

journal_title：BMJ open

authors： Vandenplas Y,Szajewska H,Benninga M,Di Lorenzo C,Dupont C,Faure C,Miqdadi M,Osatakul S,Ribes-Konickx C,Saps M,Shamir R,Staiano A,BITSS Study Group.

更新日期：2017-03-29 00:00:00

abstract：INTRODUCTION:Auditory verbal hallucinations (AVH) are prevalent experiences that can induce distress and impede social functioning. While most voice hearers benefit from antipsychotic medication or cognitive-behavioural therapy, additional effective interventions are needed to reduce the burden of experiencing AVH. 'Te...

journal_title：BMJ open

authors： Jongeneel A,Scheffers D,Tromp N,Nuij C,Delespaul P,Riper H,van der Gaag M,van den Berg D

更新日期：2018-03-06 00:00:00

abstract：OBJECTIVES:This study reviews the current state of the published peer-reviewed literature related to physician burnout and two quality of care dimensions. The purpose of this systematic literature review is to address the question, 'How does physician burnout affect the quality of healthcare related to the dimensions o...

journal_title：BMJ open

authors： Dewa CS,Loong D,Bonato S,Trojanowski L

更新日期：2017-06-21 00:00:00

abstract：INTRODUCTION:Obesity is a global epidemic and is a risk factor for developing other comorbidities. Young adulthood is a critical period for body weight change and establishing healthy lifestyle behaviours. The 'Freshman 15' suggests that undergraduate students gain 15 lbs (6.8 kg) during their first year of university,...

journal_title：BMJ open

authors： Morassut RE,Langlois C,Alyass A,Ishola AF,Yazdi FT,Mayhew AJ,Reddon H,MacKillop J,Pigeyre M,Meyre D

更新日期：2017-12-10 00:00:00

abstract：OBJECTIVES:Healthcare professionals are expected to firmly ground their practice in sound evidence. That implies that they know and use evidence-based medicine (EBM). In this study, our aim was to know how often health professionals actually made use of EBM in their daily practice. DESIGN:A questionnaire survey of hea...

journal_title：BMJ open

authors： Lafuente-Lafuente C,Leitao C,Kilani I,Kacher Z,Engels C,Canouï-Poitrine F,Belmin J

更新日期：2019-03-30 00:00:00

abstract：INTRODUCTION:Psychosocial factors are increasingly recognised as important determinants of cardiovascular disease risk. The North Texas Heart Study aims to understand the mechanisms responsible for this association with a focus on social vigilance (ie, scanning the environment for social threats). There is also growing...

journal_title：BMJ open

authors： Ruiz JM,Taylor DJ,Uchino BN,Smith TW,Allison M,Ahn C,Johnson JJ,Smyth JM

更新日期：2017-08-14 00:00:00

abstract：OBJECTIVE:The objective of this study was to assess the effects of long-term offshore work on cerebral oxygenation oscillations in sailors based on the wavelet phase coherence (WPCO) of near-infrared spectroscopy (NIRS) signals. METHODS:The fatigue severity scale (FSS) was first applied to assess the fatigue level of ...

journal_title：BMJ open

authors： Bu L,Li J,Li F,Liu H,Li Z

更新日期：2016-11-03 00:00:00

abstract：INTRODUCTION:Cancer diagnosis in primary care is an important challenge for general practitioners (GPs) due to the relatively low frequency of any single type of cancer and the heterogeneous signs and symptoms that can be present. In addition to analytical reasoning, GPs may become aware of gut feelings (GFs) as they s...

journal_title：BMJ open

authors： Oliva-Fanlo B,March S,Medina D,Martín-Rabadán M,Tamborero G,Stolper E,Esteva M

更新日期：2019-10-28 00:00:00

abstract：OBJECTIVES:To establish the prevalence and correlates of continuum beliefs for five mental illnesses in a multiethnic population and to explore its association with stigma. DESIGN:A community-based, cross-sectional study. SETTING:A national study in a multiethnic Asian country. PARTICIPANTS:A comprehensive study of ...

journal_title：BMJ open

authors： Subramaniam M,Abdin E,Picco L,Shahwan S,Jeyagurunathan A,Vaingankar JA,Chong SA

更新日期：2017-04-05 00:00:00

abstract：INTRODUCTION:In children with asthma, daily symptoms and exacerbations have a significant impact on the quality of life of both children and parents. More effective use of asthma medication and, consequently, better asthma control is advocated, since both overtreatment and undertreatment are reported in primary care. T...

journal_title：BMJ open

authors： Bousema S,Verwoerd AJ,Goossens LM,Bohnen AM,Bindels PJE,Elshout G

更新日期：2019-09-27 00:00:00

abstract：INTRODUCTION:A significant proportion of the global burden of disease has been attributed to mental and behavioural disorders. People with mental disorders (MDs) have lower levels of health-related quality of life than those without MDs. Several studies have shown that in low-resource countries, a range of social deter...

journal_title：BMJ open

authors： Uddin MN,Bhar S,Al Mahmud A,Islam FMA

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:The proper use of safety measures by welders is an important way of preventing and/or reducing a variety of health hazards that they are exposed to during welding. There is a lack of knowledge about hazards and personal protective equipments (PPEs) and the use of PPE among the welders in Nepal is limited. We ...

journal_title：BMJ open

authors： Budhathoki SS,Singh SB,Sagtani RA,Niraula SR,Pokharel PK

更新日期：2014-06-02 00:00:00

abstract：INTRODUCTION:Parkinson's disease is the second most common chronic neurodegenerative condition with bladder dysfunction affecting up to 71%. Symptoms affect quality of life and include urgency, frequency, hesitancy, nocturia and incontinence. Addressing urinary dysfunction is one of the top 10 priority research areas i...

journal_title：BMJ open

authors： McClurg D,Panicker J,Walker RW,Cunnington A,Deane KHO,Harari D,Elders A,Booth J,Hagen S,Mason H,Stratton S

更新日期：2020-02-17 00:00:00

abstract：INTRODUCTION:Expectant mothers in low-income and middle-income countries often lack access to vital information about pregnancy, preparation for birth and best practices when caring for their newborn. Innovative solutions are needed to bridge this knowledge gap and dramatically improve maternal and neonatal health in t...

journal_title：BMJ open

authors： Su Y,Yuan C,Zhou Z,Heitner J,Campbell B

更新日期：2016-08-10 00:00:00

abstract：BACKGROUND:In areas where HIV and intestinal schistosomiasis are highly endemic, co-infections of the two diseases in a single human host are frequent. Evidence in adult populations indicates that HIV and intestinal schistosomiasis are associated with negative health impacts. However, the topic of HIV and schistosomias...

journal_title：BMJ open

authors： Mazigo HD,Kirway L,Ambrose EA

更新日期：2019-07-24 00:00:00

abstract：OBJECTIVES:This study compared the impact of two different 8-week mindfulness based courses (.b Foundations and Mindfulness-Based Stress Reduction (MBSR)), delivered to school teachers, on quantitative (stress, anxiety and depression) and qualitative (experience, acceptability and implementation) outcomes. DESIGN:A mi...

journal_title：BMJ open

authors： Todd C,Cooksey R,Davies H,McRobbie C,Brophy S

更新日期：2019-07-04 00:00:00

abstract：OBJECTIVES:Nursing home residents (NHRs) are frequently suffering from multimorbidity, functional and cognitive impairment, often leading to hospital admissions. Studies have found that male NHRs are more often hospitalised. The influence of age is inconclusive. We aimed to investigate the epidemiology of hospitalisati...

journal_title：BMJ open

authors： Hoffmann F,Allers K

更新日期：2016-10-08 00:00:00

abstract：OBJECTIVE:To investigate whether two primary care activities that are framed as indicators of primary care quality (comprehensive care plans and annual reviews of physical health) influence unplanned utilisation of hospital services for people with serious mental illness (SMI). DESIGN, SETTING, PARTICIPANTS:Retrospect...

journal_title：BMJ open

authors： Ride J,Kasteridis P,Gutacker N,Kronenberg C,Doran T,Mason A,Rice N,Gravelle H,Goddard M,Kendrick T,Siddiqi N,Gilbody S,Dare CR,Aylott L,Williams R,Jacobs R

更新日期：2018-11-28 00:00:00

abstract：INTRODUCTION:With almost 50% of cases preventable and the Australian National Bowel Cancer Screening Program in place, colorectal cancer (CRC) is a prime candidate for investment to reduce the cancer burden. The challenge is determining effective ways to reduce morbidity and mortality and their implementation through p...

journal_title：BMJ open

authors： Feletto E,Lew JB,Worthington J,He E,Caruana M,Butler K,Hui H,Taylor N,Banks E,Barclay K,Broun K,Butt A,Carter R,Cuff J,Dessaix A,Ee H,Emery J,Frayling IM,Grogan P,Holden C,Horn C,Jenkins MA,Kench JG,Laaksone

更新日期：2020-06-21 00:00:00

abstract：BACKGROUND:Pembrolizumab was recently demonstrated to have survival benefit in patients with recurrent or metastatic head and neck squamous cell carcinoma (r/mHNSCC). However, the cost-effectiveness of pembrolizumab versus chemotherapy in China remains uncertain. OBJECTIVE:This analysis aimed to describe the cost-effe...

journal_title：BMJ open

authors： Xin W,Ding H,Fang Q,Zheng X,Tong Y,Xu G,Yang G

更新日期：2020-12-18 00:00:00

abstract：OBJECTIVES:Exposure to tobacco and alcohol content in audio-visual media is a risk factor for smoking and alcohol use in young people. Previous UK research has quantified tobacco and alcohol content in films and broadcast television but not that of video-on-demand (VOD) services such as Netflix and Amazon Prime. Furthe...

journal_title：BMJ open

authors： Barker AB,Smith J,Hunter A,Britton J,Murray RL

更新日期：2019-02-13 00:00:00

abstract：OBJECTIVES:For people with end-stage renal disease requiring haemodialysis, exercise can improve aspects of quality of life (QoL). However, the relative benefits and risks of different types of exercise in this population are unknown. Therefore, this pilot study aimed to evaluate the feasibility of a main study evaluat...

journal_title：BMJ open

authors： Thompson S,Klarenbach S,Molzahn A,Lloyd A,Gabrys I,Haykowsky M,Tonelli M

更新日期：2016-09-06 00:00:00

abstract：OBJECTIVE:Recent studies have shown that people with mental illnesses have higher mortality and morbidity rates due to long-term conditions and lifestyle diseases. This knowledge has led to health promotion initiatives in mental health care to improve the physical health of people with mental illness. This article expl...

journal_title：BMJ open

authors： Møller JE,Møller A,Ledderer L

更新日期：2020-12-24 00:00:00

abstract：INTRODUCTION:Pharmacological interventions to address behavioural and psychological symptoms of dementia (BPSD) can have undesirable side effects, therefore non-pharmacological approaches to managing symptoms may be preferable. Past studies show that music therapy can reduce BPSD, and other studies have explored how fo...

journal_title：BMJ open

authors： Baker FA,Bloska J,Braat S,Bukowska A,Clark I,Hsu MH,Kvamme T,Lautenschlager N,Lee YC,Smrokowska-Reichmann A,Sousa TV,Stensaeth KA,Tamplin J,Wosch T,Odell-Miller H

更新日期：2019-11-19 00:00:00

abstract：OBJECTIVES:The study aims to compare the risk of chronic kidney diseases (CKDs) between patients with schizophrenia using first and second-generation antipsychotics. SETTING:Datasets of 2000-2013 National Health Insurance in Taiwan were used. PARTICIPANTS:The National Health Insurance reimbursement claims data have b...

journal_title：BMJ open

authors： Wang HY,Huang CL,Feng IJ,Tsuang HC

更新日期：2018-05-24 00:00:00

abstract：OBJECTIVES:Fibre-endoscopic evaluation of swallowing (FEES) to detect dysphagia is gaining more and more importance as a diagnostic tool. Therefore, we have investigated the impact of FEES in neurological patients in a clinical setting. DESIGN:Cross-sectional hospital-based registry. SETTING:Primary acute care in a n...

journal_title：BMJ open

authors： Braun T,Juenemann M,Viard M,Meyer M,Fuest S,Reuter I,Kaps M,Prosiegel M,Tanislav C

更新日期：2018-03-06 00:00:00

abstract：INTRODUCTION:Idiopathic subglottic stenosis (iSGS) is an unexplained progressive obstruction of the upper airway that occurs almost exclusively in adult, Caucasian women. The disease is characterised by mucosal inflammation and localised fibrosis resulting in life-threatening blockage of the upper airway. Because of hi...

journal_title：BMJ open

authors： Gelbard A,Shyr Y,Berry L,Hillel AT,Ekbom DC,Edell ES,Kasperbauer JL,Lott DG,Donovan DT,Garrett CG,Sandhu G,Daniero JJ,Netterville JL,Schindler JS,Smith ME,Bryson PC,Lorenz RR,Francis DO

更新日期：2018-04-10 00:00:00

abstract：INTRODUCTION:Multiple interventions are effective for migraine prophylaxis. However, the comparative effectiveness of these interventions is still not clear. Therefore, the aim of this study is to summarise the direct and indirect evidence for pharmacological and non-pharmacological interventions to prevent migraine at...

journal_title：BMJ open

authors： Zheng H,Chen M,Huang D,Li J,Chen Q,Fang J

更新日期：2015-05-06 00:00:00

abstract：OBJECTIVES:To investigate the risk of emergency hospital admissions for violence (EHAV) associated with demographic and socioeconomic factors in Wales between 2007/2008 and 2013/2014, and to describe the site of injury causing admission. DESIGN:Database analysis of 7 years' hospital admissions using the Patient Episod...

journal_title：BMJ open

authors： Long SJ,Fone D,Gartner A,Bellis MA

更新日期：2016-08-24 00:00:00

abstract：INTRODUCTION:Seasonal influenza vaccination is recommended for all individuals aged 65 years and over and in individuals younger than 65 years with comorbidities. There is good evidence of vaccine effectiveness (VE) in young healthy individuals but less robust evidence for effectiveness in the populations targeted for ...

journal_title：BMJ open

authors： Lone NI,Simpson C,Kavanagh K,Robertson C,McMenamin J,Ritchie L,Sheikh A

更新日期：2012-03-15 00:00:00