Abstract:
BACKGROUND:Bacteraemia of the donor is not considered to be contraindication of organ procurement. On the other hand, infection of solid organ transplant recipients remains to be a major cause of their morbidity and mortality. When using organs from bacteraemic donors, individual risks need to be assessed and the appropriate antibiotic treatment applied. CASE PRESENTATION:In this case series we report several serious donor-derived infectious complications in four out of five recipients of different organs from one single donor in the early posttransplant period. Donor-transmitted multi-drug resistant strains of Escherichia coli and Klebsiella pneumonia was confirmed by both serologic and molecular testing. CONCLUSIONS:To prevent donor-derived infections, careful microbiological screening followed by targeted antibiotic treatment is essential. Although such complications can never by completely prevented, a high index for potential bacterial infection in organ donors and transplant recipients should be routinely employed.
journal_name
BMC Surgjournal_title
BMC surgeryauthors
Kieslichova E,Protus M,Nemcova D,Uchytilova Edoi
10.1186/s12893-019-0574-9subject
Has Abstractpub_date
2019-08-14 00:00:00pages
111issue
1issn
1471-2482pii
10.1186/s12893-019-0574-9journal_volume
19pub_type
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