Abstract:
BACKGROUND:Saturated fatty acids (SFA) have been reported to promote inflammation. Nevertheless, evidence linking dietary SFA and low-grade inflammation in adolescents is scarce and inconsistent. The modulatory role of physical activity (PA) on fat metabolism and inflammation may provide a potential explanation. Thus, we assessed the association of dietary SFA with high-sensitivity C-reactive protein (hsCRP), a marker of low-grade inflammation, in 15-year-olds, and evaluated possible interactions between dietary SFA and different levels of PA. METHODS:Children participating in the 15-year follow-ups of the GINIplus and LISA German birth cohort studies were included (N = 824). SFA intake was estimated by means of a food frequency questionnaire and PA recorded by accelerometers. Average daily minutes of PA were classified into "sedentary", "light" and "moderate-to-vigorous" (MVPA), using Freedson's cut-offs. HsCRP concentrations were measured in serum and categorized into 3 sex-specific levels (below detection limit (I), above 75th percentile (III), in between (II)). Sex-stratified cross-sectional associations between SFA and hsCRP were assessed using multinomial logistic regression, adjusting for potential confounders. Interaction terms were included between SFA and the different PA levels; and if significant interactions were observed, analyses stratified by tertiles of the relevant PA levels were performed. Relative risk ratios (RRR) and 95% confidence intervals (95%CI) were presented for a 1% increase in SFA. RESULTS:An inverse association was observed between SFA intake and hsCRP (II vs. I) in males (RRR = 0.85 [95%CI = 0.76;0.96], p = 0.008), whereas no significant association was observed in females. A significant interaction was observed with "sedentary" and "light" PA but not with MVPA in both sexes (p < 0.05). Stratified analyses indicated a significant inverse association between SFA and medium hsCRP levels in males in the highest light PA tertile (hsCRP II vs. I: 0.67 [0.517;0.858], p = 0.002). CONCLUSION:Our findings do not support a detrimental role of dietary SFA in low-grade inflammation among adolescents. In males, higher dietary SFA was associated with lower hsCRP, although this should be interpreted in the context of possibly correlated nutrients. Children spending the most time in light PA drove the observed inverse association, suggesting a synergistic effect of SFA and lifestyle PA in the resultant inflammatory response.
journal_name
BMC Public Healthjournal_title
BMC public healthauthors
Harris CP,von Berg A,Berdel D,Bauer CP,Schikowski T,Koletzko S,Heinrich J,Schulz H,Standl Mdoi
10.1186/s12889-019-7113-6subject
Has Abstractpub_date
2019-06-25 00:00:00pages
818issue
1issn
1471-2458pii
10.1186/s12889-019-7113-6journal_volume
19pub_type
杂志文章abstract:BACKGROUND:Societal expenditures on work-disability benefits is high in most Western countries. As a precursor of long-term work restrictions, long-term sickness absence (LTSA) is under continuous attention of policy makers. Different healthcare professionals can play a role in identification of persons at risk of LTSA...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-020-08843-x
更新日期:2020-05-15 00:00:00
abstract:BACKGROUND:Efforts undertaken during the Return-to-Work (RTW) process need to be sufficient in order to optimize the quality of the RTW process. The purpose of this study was to explore factors relevant to Return-to-Work Effort Sufficiency (RTW-ES) in cases of sick-listed employees with a Depressive Disorder (DD). MET...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-12-103
更新日期:2012-02-06 00:00:00
abstract:BACKGROUND:Overweight in children and adolescents has reached dimensions of a global epidemic during recent years. Simultaneously, information and communication technology use has rapidly increased. METHODS:A population-based sample of Finnish twins born in 1983-1987 (N = 4098) was assessed by self-report questionnair...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-7-24
更新日期:2007-02-26 00:00:00
abstract:BACKGROUND:A recent community-based disease management (CBDM) pilot study reported a 20.5% prevalence of hypertension and a 0.5 and 3.6% prevalence of stroke and coronary heart disease (CHD), respectively, in an elderly population (mean age 65 years) in the Xin Jiang autonomous region of China. The CBDM was initiated i...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-020-09157-8
更新日期:2020-06-29 00:00:00
abstract:BACKGROUND:Waist circumference has been identified as a valuable predictor of cardiovascular risk in children. The development of waist circumference percentiles and cut-offs for various ethnic groups are necessary because of differences in body composition. The purpose of this study was to develop waist circumference ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-10-82
更新日期:2010-02-19 00:00:00
abstract:BACKGROUND:The epidemic of diabetes continues leaving an enormous and growing burden of chronic disease to public health. This study investigates this growing burden of diabetes independent of increasing BMI in a large population based female sample, 2006-2010. METHODS:Serial cross-sectional data using the Behavioral ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-14-954
更新日期:2014-09-15 00:00:00
abstract:BACKGROUND:Diabetes is a leading cause of death and disability in the United States, and its precursor, pre-diabetes, is estimated to occur in one-third of American adults. Understanding the geographic disparities in the distribution of these conditions and identifying high-prevalence areas is critical to guiding contr...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-020-09311-2
更新日期:2020-08-12 00:00:00
abstract:BACKGROUND:Screening programmes should be organized to translate theoretical efficacy into effectiveness. An evidence-based organizational model of colorectal cancer screening (CRCS) should assure feasibility and high compliance. METHODS:A multidisciplinary Working Group (WG), reviewed literature and guidelines to def...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-8-318
更新日期:2008-09-19 00:00:00
abstract:BACKGROUND:Physical inactivity levels are rising in many countries with major implications for the prevalence of non-communicable diseases and the general health of the population worldwide. We conducted this study to examine leisure-time physical activity levels among African adults in an urban setting. METHODS:We co...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-14-529
更新日期:2014-05-29 00:00:00
abstract:BACKGROUND:Despite an increasing body of knowledge concerning gender and lifestyle factors as determinants of sickness absence in well-developed countries, the relationship between these variables has not been elucidated in emerging economic power countries, where the burden of non-communicable diseases is particularly...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-14-317
更新日期:2014-04-06 00:00:00
abstract:BACKGROUND:A "diet high in sodium" is the second most important dietary risk factor for health loss identified in the Global Burden of Disease Study 2013. We therefore aimed to model health gains and costs (savings) of salt reduction interventions related to salt substitution and maximum levels in bread, including by e...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-016-3102-1
更新日期:2016-05-23 00:00:00
abstract:BACKGROUND:News media are key sources of information regarding tobacco issues, and help set the tobacco control policy agenda. We examined US news coverage of voluntarily smokefree restaurants and bars in locales without mandatory policies to understand how such initiatives are perceived. METHODS:We searched three onl...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-015-2094-6
更新日期:2015-08-08 00:00:00
abstract:BACKGROUND:The use of khat among youths can be harmful leading to decreased academic performance, increased risk of contracting HIV and other sexually transmitted diseases or other psychiatric symptoms. It is believed to be one of the factors associated with unprotected risky sexual behavior predisposing the youth for ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-13-1199
更新日期:2013-12-18 00:00:00
abstract:BACKGROUND:Due to the large mortality from inactivity-related non-communicable diseases in low- and middle- income countries, accurate assessment of physical activity is important for surveillance, monitoring and understanding of physical (in)activity epidemiology in many of these countries. Research on relative perfor...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-016-3693-6
更新日期:2016-09-22 00:00:00
abstract:BACKGROUND:Long-term multicentre studies are subject to numerous factors that may affect the integrity of their conclusions. Quality control and standardization of data collection are crucial to minimise the biases induced by these factors. Nevertheless, tools implemented to manage biases are rarely described in public...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-016-3439-5
更新日期:2016-08-25 00:00:00
abstract:BACKGROUND:Mass screening for celiac disease (CD) as a public health intervention is controversial. Prior to implementation, acceptability to the targeted population should be addressed. We aimed at exploring adolescents' and parents' experiences of having the adolescents' CD detected through mass screening, and their ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-11-822
更新日期:2011-10-21 00:00:00
abstract:BACKGROUND:The ATLAS programme aims to promote and implement HIV self-testing (HIVST) in three West African countries: Côte d'Ivoire, Mali, and Senegal. During 2019-2021, in close collaboration with the national AIDS implementing partners and communities, ATLAS plans to distribute 500,000 HIVST kits through eight deliv...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-021-10212-1
更新日期:2021-01-21 00:00:00
abstract:BACKGROUND:As the world's largest developing country, China has entered into the epidemiological phase characterized by high life expectancy and high morbidity and mortality from chronic diseases. Cardiovascular diseases, chronic obstructive pulmonary diseases, and malignant tumors have become the leading causes of dea...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-12-988
更新日期:2012-11-16 00:00:00
abstract:BACKGROUND:Self-rated health is a measure expressing the general condition of health of individuals. Self-rated health studies are common in developed countries and in some developing regions. Despite increasing proportion of adult and older population in sub-Saharan Africa and poor population health indicators, there ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-016-3552-5
更新日期:2016-08-24 00:00:00
abstract:BACKGROUND:Nearly all California casinos currently allow smoking, which leads to potentially high patron exposure to secondhand tobacco smoke pollutants. Some argue that smoking restrictions or bans would result in a business drop, assuming > 50% of patrons smoke. Evidence in Nevada and responses from the 2008 Californ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-12-819
更新日期:2012-09-22 00:00:00
abstract:BACKGROUND:Colorectal cancer is the third and fourth leading cause of cancer incidence and mortality among men and women, respectively in Iran. However, the role of dietary factors that could contribute to this high cancer incidence remains unclear. The aim of this study was to determine major dietary patterns and its ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-13-222
更新日期:2013-03-12 00:00:00
abstract:BACKGROUND:Colorectal cancer screening uptake within the South Asian population in England is approximately half that of the general population (33 % vs 61 %), and varies by Muslim (31.9 %), Sikh (34.6 %) and Hindu (43.7 %) faith background. This study sought to explore reasons for low uptake of CRC screening in South ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-015-2334-9
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Few studies have evaluated health impacts, especially biomarker changes, following implementation of a new environmental policy. This study examined changes in water fluoride, urinary fluoride (UF), and bone metabolism indicators in children after supplying low fluoride public water in endemic fluorosis area...
journal_title:BMC public health
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2458-13-156
更新日期:2013-02-20 00:00:00
abstract:BACKGROUND:Projections of health and social care need are highly sensitive to assumptions about cohort trends in health and disability. We use a repeated population-based cross-sectional study from the Cambridgeshire centre of the UK Medical Research Council Cognitive Function and Ageing Study to investigate trends in ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-7-156
更新日期:2007-07-13 00:00:00
abstract:BACKGROUND:Physical inactivity is deemed to be the fourth leading cause for premature death. Nevertheless, only a minority of children and adolescents in Germany fulfil the guideline of the World Health Organization of at least 60 min of moderate-to-vigorous physical activity per day. Children and adolescents with a lo...
journal_title:BMC public health
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12889-019-6817-y
更新日期:2019-05-06 00:00:00
abstract:BACKGROUND:The UK has one of the highest rates for deaths from fire and flames in children aged 0-14 years compared to other high income countries. Evidence shows that smoke alarms can reduce the risk of fire-related injury but little exists on their cost-effectiveness. We aimed to compare the cost effectiveness of dif...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-14-459
更新日期:2014-05-16 00:00:00
abstract:BACKGROUND:In adults, as little as 10 minutes of moderate physical activity (PA) three times a day can help prevent non-communicable diseases and prolong life expectancy. The aim of the study was to evaluate the process and impact of scaling up a complex intervention (PAFES) implemented in Catalonia, aimed to increase ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-018-5773-2
更新日期:2018-08-03 00:00:00
abstract:BACKGROUND:The aim of this paper was to ascertain whether greater familiarity with a smartphone or tablet was associated with participants' preferred mobile delivery modality for eHealth interventions. METHODS:Data from 1865 people who participated in the Australian Health and Social Science panel study were included ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-016-3316-2
更新日期:2016-07-22 00:00:00
abstract:BACKGROUND:Human Papilloma Virus (HPV) vaccine has undergone successful trials and has recently been approved for use for the primary prevention of cervical cancer. The aim of this study was to determine knowledge and attitudes towards HPV vaccination. METHODS:Semi-structured interview and questionnaire delivered in a...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-8-368
更新日期:2008-10-23 00:00:00
abstract:BACKGROUND:Common mental disorders are frequent psychiatric comorbid conditions among people with HIV/AIDS. The presence of such psychiatric disorders negatively affects the treatment adherence, viral load suppression, quality of life, treatment outcomes and functionality of people with HIV/AIDS. However, available stu...
journal_title:BMC public health
pub_type: 杂志文章,meta分析
doi:10.1186/s12889-020-08800-8
更新日期:2020-05-14 00:00:00