Abstract:
BACKGROUND:Chronic low back pain (cLBP) affects millions of Americans and costs billions. Studies suggest a link between cLBP and joint hypermobility. METHODS:We conducted cross-sectional primary analyses of joint hypermobility and cLBP, lumbar spine osteoarthritis (OA), and lumbar facet joint OA (FOA) in 3 large studies-the Generalized Osteoarthritis Study, Genetics of Generalized Osteoarthritis Study, and Johnston County Osteoarthritis Project (total n = 5072). Associations of joint hypermobility and Beighton trunk flexion with cLBP and lumbar OA were estimated using separate adjusted logistic regression models. Adjusted pooled odds ratios (pORs) and 95% confidence intervals (CIs) were then summarized-using random effect univariate, multivariate crude, and adjusted models-and heterogeneity was determined (I2 statistic). RESULTS:In univariate models, hypermobility was associated with symptomatic FOA (pOR = 0.64 [95% CI 0.44, 0.93]) but this result was not found in the multivariate models. In multivariate adjusted models, hypermobility was not significantly associated with cLBP and lumbar OA, but trunk flexion was inversely associated with cLBP (pOR = 0.40 [95% 0.26, 0.62]), spine OA (pOR = 0.66 [95% CI 0.50, 0.87]), symptomatic spine OA (pOR = 0.39 [95% CI 0.28, 0.53]), and symptomatic FOA (pOR = 0.53 [95% CI 0.37, 0.77]). Generally, between-study heterogeneity was moderate-high. CONCLUSIONS:Hypermobility was not associated with cLBP or lumbar OA. The inverse association of trunk flexion with cLBP and lumbar OA may indicate a role for a flexible spine in avoiding or managing these conditions.
journal_name
BMC Musculoskelet Disordjournal_title
BMC musculoskeletal disordersauthors
Goode AP,Cleveland RJ,Schwartz TA,Nelson AE,Kraus VB,Hillstrom HJ,Hannan MT,Flowers P,Renner JB,Jordan JM,Golightly YMdoi
10.1186/s12891-019-2523-2subject
Has Abstractpub_date
2019-04-09 00:00:00pages
158issue
1issn
1471-2474pii
10.1186/s12891-019-2523-2journal_volume
20pub_type
杂志文章abstract:BACKGROUND:Many studies show a relation between reduced lumbar motor control (LMC) and low back pain (LBP). However, test circumstances vary and during test performance, subjects may change position. In other words, the reliability--i.e. reproducibility and validity--of tests for LMC should be based on quantitative dat...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章
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更新日期:2009-01-13 00:00:00
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更新日期:2020-02-21 00:00:00
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更新日期:2020-05-07 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,随机对照试验
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