Abstract：
BACKGROUND:Two-stage exchange arthroplasty is still the preferred treatment choice for chronic PJI. However, the results remain unpredictable. We analyzed the treatment success of patients with an infected hip prosthesis, who were treated according to a standardized algorithm with a multidisciplinary team approach and evaluated with a strict definition of failure. METHODS:In this single-center prospective cohort study, all hip PJI episodes from March 2013 to May 2015 were included. Treatment failure was assessed according to the Delphi-based consensus definition. The Kaplan-Meier survival method was used to estimate the probability of infection-free survival. Patients were dichotomized into two groups depending on the number of previous septic revisions, duration of prosthesis-free interval, positive culture with difficult-to-treat microorganisms, microbiology at explantation, and microbiology at reimplantation. RESULTS:Eighty-four patients with hip PJI were the subject of this study. The most common isolated microorganisms were coagulase-negative staphylococci (CNS) followed by Staphylococcus aureus and Propionibacterium. Almost half of the study cohort (46%) had at least one previous septic revision before admission. The Kaplan-Meier estimated infection-free survival after 3 years was 89.3% (95% CI, 80% to 94%) with 30 patients at risk. The mean follow-up was 33.1 months (range, 24-48 months) with successful treatment of PJI. There were no statistical differences in infect eradication rate among the dichotomized groups. CONCLUSIONS:High infect eradication rates were achieved in a challenging cohort using a standardized two-stage exchange supported by a multidisciplinary approach.
journal_name
J Orthop Surg Resjournal_title
Journal of orthopaedic surgery and researchauthors
Akgün D,Müller M,Perka C,Winkler Tdoi
10.1186/s13018-019-1122-0subject
Has Abstractpub_date
2019-03-13 00:00:00pages
78issue
1issn
1749-799Xpii
10.1186/s13018-019-1122-0journal_volume
14pub_type
杂志文章abstract：BACKGROUND:Numerous quantitatively based studies measuring the association between gout and the risk of fractures remain inconclusive. In order to determine whether gout could increase the risk of fractures, a meta-analysis was performed systematically. METHODS:Electronic databases, MEDLINE/PubMed, Embase, and Cochran...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章,meta分析,评审
doi：10.1186/s13018-019-1317-4
更新日期：2019-08-27 00:00:00
abstract：BACKGROUND:This study aimed to investigate the effects of silk fiber (SF)/calcium phosphate cement (CPC) biocomposite on repairing radial bone defects in rabbits. METHODS:Four-month-old New Zealand rabbits were selected to create a bilateral radial bone defect model and divided into four groups according to implanted ...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-017-0529-8
更新日期：2017-02-21 00:00:00
abstract：PURPOSE:To compare the specificity and sensitivity of preoperative D-dimer and age-adjusted D-dimer value for predicting the incidence of the DVT preoperatively in total joint arthroplasty (TJA) patients. METHODS:We enrolled 406 patients finally above 50 years old. Everyone had done ultrasonography bedside, and D-dime...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-020-02172-w
更新日期：2021-01-25 00:00:00
abstract：OBJECTIVE:To compare the efficacy of medial and lateral entry pinning with lateral entry pinning for percutaneous fixation of displaced (Gartland type II and type III) extension type supracondylar fractures of the humerus in children. METHODS:The study was a single center, prospective, randomized controlled clinical t...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章,随机对照试验
doi：10.1186/1749-799X-7-6
更新日期：2012-02-15 00:00:00
abstract：BACKGROUND:Disease modifying anti-rheumatic drugs (DMARDs) may interfere with bone healing. Previous studies give conflicting advice regarding discontinuation of these drugs in the peri-operative setting. No consensus exists in current practice especially with the newer DMARDs such as Leflunomide, Etanercept, and Infli...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/1749-799X-4-17
更新日期：2009-05-26 00:00:00
abstract：BACKGROUND:Percutaneous fixation with cannulated screws is an effective method for treating medial malleolar epiphyseal fractures, which comprise a portion of bimalleolar and trimalleolar fractures. Lateral malleolar fractures also need to be fixed to achieve anatomical reduction and absolute stable fixation of the ank...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-019-1287-6
更新日期：2019-08-08 00:00:00
abstract：BACKGROUND:Intertrochanteric fracture (ITF) is increasing with the rapid increase in the aging population, often causes a high mortality rate in old patients and increases the economic burden of the family and society. ERAS (Enhanced Recovery after Surgery) is a powerful guarantee for patients to accelerate their recov...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章,随机对照试验
doi：10.1186/s13018-020-01586-w
更新日期：2020-03-05 00:00:00
abstract：BACKGROUND:Femoral trochanteric fractures are common among older adults. In the reduction of trochanteric fractures, acquiring the support of the anterior cortex at the fracture site on lateral view immediately after surgery is important. However, even if the cortical support is acquired, postoperative displacement due...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-018-1011-y
更新日期：2018-11-27 00:00:00
abstract：BACKGROUND:In recent years, the modified Dunn osteotomy has gained popularity to treat slipped capital femoral epiphysis (SCFE) with various complication rates. Most studies included patients with different severities. This study aimed to determine (1) the radiological and clinical outcome, (2) the health-related quali...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-019-1433-1
更新日期：2019-11-08 00:00:00
abstract：BACKGROUND:Surgical site infection (SSI) was the most common complication of tibial plateau fracture after open reduction and internal fixation (ORIF). Severe infections even required repeat surgeries, which would cause serious psychological harm to patients and increased the economic burden of treatment. In order to i...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-020-01885-2
更新日期：2020-08-24 00:00:00
abstract：: The treatment of an above knee amputee who has sustained a fracture of femoral neck is a challenge for both the orthopaedic surgeon and the rehabilitation team. We present a case of such a patient and discuss different difficulties in his treatment. ...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/1749-799X-4-30
更新日期：2009-07-31 00:00:00
abstract：BACKGROUND:This study was undertaken to establish a rat bipedal walking model of cervical kyphosis (CK) associated with chronic forward flexed neck and assess the effects of chronic forward flexed neck on endplate chondrocytes. METHODS:Forty-eight 1-month-old Sprague-Dawley rats were randomly divided into 3 groups: fo...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-020-02124-4
更新日期：2021-01-04 00:00:00
abstract：BACKGROUND:The anterior iliac crest (AIC) and proximal tibia (PT) are common donor sites for autologous bone graft harvesting. We compared pain levels at these harvest sites on 1 day, 5 days, 2 weeks, 4 weeks, and 8 weeks post-harvest. METHODS:We retrospectively reviewed 18 patients undergoing autologous bone grafting...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-018-0820-3
更新日期：2018-05-16 00:00:00
abstract：OBJECTIVE:The purpose of this study was to investigate the effects of the number of fused segments, the timing of surgery and their interaction on the prognosis of patients with cervical spinal cord injury without fracture and dislocation (CSCIWFD), and to determine the appropriate time restrictions for early surgery i...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-019-1487-0
更新日期：2019-12-05 00:00:00
abstract：BACKGROUND:Congenital muscular torticollis (CMT) is due to contracture of the sternocleidomastoid muscle which may cause activity limitations of the neck, tilt of the head, craniofacial asymmetry, and deformity of the skull. The authors present their experience of arthroscopic tight fibrous band release with radiofrequ...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-018-0801-6
更新日期：2018-05-03 00:00:00
abstract：BACKGROUND:The Orthopaedic Data Evaluation Panel (ODEP) monitors the performance of primary total knee arthroplasty (TKA) implants against guidance provided by the National Institute for Health and Care Excellence (NICE) and issues ratings based upon survivorship data meeting or exceeding 95 % at 10-year follow-up. The...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-016-0388-8
更新日期：2016-04-19 00:00:00
abstract：PURPOSE:The aim of this retrospective observational study of one cohort was to evaluate the long-term outcome in patients younger than 60 years after total hip arthroplasty using a straight uncemented stem and an uncemented threaded cup. METHODS:Between 1986 and 1987, 75 hips of 75 patients (mean age, 53.35 ± 6.17 yea...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-020-02102-w
更新日期：2020-11-26 00:00:00
abstract：BACKGROUND:We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the efficacy and safety of local infiltration anesthesia (LIA) versus epidural analgesia (EPA) for postoperative pain control in total knee arthroplasty (TKA). METHODS:In December 2017, a systematic compute...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章,meta分析,评审
doi：10.1186/s13018-018-0770-9
更新日期：2018-05-16 00:00:00
abstract：OBJECTIVE:The aim of this study is to investigate the morphological characteristics of distal radius die-punch fracture (DRDPF) with different types, based on the three-column theory. METHODS:The imaging data of 560 patients diagnosed with DRDPF were reviewed and divided into single-column, double-column, or three-col...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-019-1453-x
更新日期：2019-11-27 00:00:00
abstract：BACKGROUND:Femoral and sciatic nerves could be damaged during various stages of the periacetabular osteotomy. Changing the position of the hip could be the most effective way of preventing nerve injuries. The purpose of the present study was to investigate the distances of the nerves to various bony landmarks with diff...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-020-01937-7
更新日期：2020-09-11 00:00:00
abstract：BACKGROUND:Ganglion cyst of cruciate ligaments is a rare lesion; the prevalence is 0.3-0.8%. The purpose of this study was to present clinical features of symptomatic posterior cruciate ligament (PCL) cyst, introduce the arthroscopic excision technique, and evaluate the clinical outcome. METHODS:A series of 11 patient...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-018-0798-x
更新日期：2018-04-13 00:00:00
abstract：BACKGROUND:Glucocorticoid (GC)-induced osteonecrosis (ON) is an important complication of medical therapy. The exact pathomechanisms of ON has not been clearly elucidated. There is a need for a reproducible animal model that better approximates the clinical scenario. METHODS:To determine the genetic susceptibility of ...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/1749-799X-6-62
更新日期：2011-12-21 00:00:00
abstract：PURPOSE:The purpose of this study was to compare the interfragmentary compression force across a simulated scaphoid fracture by two commonly used compression screw systems; the Acutrak 2 Standard and the 3.0 mm Synthes headless compression screw. METHODS:Sixteen (8 pairs; 6 female, 2 male) cadaver scaphoids were rando...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/1749-799X-6-27
更新日期：2011-06-07 00:00:00
abstract：BACKGROUND:The infrapatellar fat pad (IPFP) or Hoffa's fat pad is often resected during total knee arthroplasty in order to improve visibility. However, the management of the IPFP during total knee arthroplasty (TKA) is the subject of an ongoing debate that has no clear consensus. The purpose of this review was to appr...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章,评审
doi：10.1186/s13018-020-01823-2
更新日期：2020-08-05 00:00:00
abstract：OBJECTIVE:Osteoarthritis (OA) is a prevalent degenerative disease caused by various factors. MicroRNAs are important regulators in OA. MiR-21-5p expression is decreased in OA cartilage, but the effects of modulating miR-21-5p on cartilage regeneration are unknown. Therefore, our aim was to investigate the effects of mi...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-019-1160-7
更新日期：2019-05-03 00:00:00
abstract：BACKGROUND:Training beginners of the pedicle screw instrumentation technique in the operating room is limited because of issues related to patient safety and surgical efficiency. Three-dimensional (3D) printing enables training or simulation surgery on a real-size replica of deformed spine, which is difficult to perfor...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-018-0788-z
更新日期：2018-04-16 00:00:00
abstract：OBJECTIVES:The purpose of this study is to identify the factors that influence the length of stay (LOS) in total knee arthroplasty (TKA) patients with an enhanced recovery after surgery (ERAS) program. METHODS:Information from 167 patients (31 males and 136 females, range from 43 years to 88 years old) who underwent t...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-019-1389-1
更新日期：2019-11-06 00:00:00
abstract：:We write in response to Lawton et al.'s (J Orthop Surg Res 12:76, 2017) important systematic review comparing the outcomes of total ankle replacement (TAR) and ankle arthrodesis (AA) after reviewing the existing literature. Traditionally, AA was the gold standard treatment for ankle osteoarthritis but there is renewed...
journal_title：Journal of orthopaedic surgery and research
pub_type： 信件
doi：10.1186/s13018-019-1190-1
更新日期：2019-05-20 00:00:00
abstract：BACKGROUND:Bone marrow lesions (BMLs) are a common finding in patients with osteoarthritis (OA), which are predictors of progression and pain related to cartilage damage in OA. The objective of the present research was to compare the short-term clinical effect of intramuscular calcitonin and oral celecoxib in treating ...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-020-01746-y
更新日期：2020-06-23 00:00:00
abstract：:Submuscular and minimally invasive plate insertion is gaining popularity reducing the need for large open approaches and resulting in a smaller operative 'footprint.' With pediatric fractures and titanium implants, fibrous and osseous ingrowth to the implant and osseous implant integration may interfere with implant r...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/1749-799X-8-21
更新日期：2013-07-11 00:00:00
