Abstract:
Background:Antimicrobial disinfectants are used as primary treatment options against pathogens on surfaces in healthcare facilities to help prevent healthcare associated infections (HAIs). On many surfaces, pathogenic microorganisms exist as biofilms and form an extracellular matrix that protects them from the antimicrobial effects of disinfectants. Disinfectants are used as all-purpose antimicrobials though very few specifically make biofilm efficacy claims. The objective of this study was to evaluate the efficacy of eight registered disinfectants (six registered by the Environmental Protection Agency and two products registered in by the European Chemical Agency) with general bactericidal claims, but currently no biofilm efficacy claims, against Staphylococcus aureus ATTC-6538 and Pseudomonas aeruginosa ATCC-15442 biofilms. We hypothesized that hydrogen peroxide and sodium hypochlorite disinfectant products would be more effective than quaternary ammonium chlorides. Methods:This study tested the bactericidal efficacy of eight registered disinfectant products against S. aureus ATCC-6538 and P. aeruginosa ATCC-15442 grown on glass coupons using a Center for Disease Control (CDC) biofilm reactor and EPA MLB SOP MB-19. Bactericidal efficacy was determined after treating coupons with disinfectants following standard EPA MLB SOP MB-20. Results:Overall, sodium hypochlorite and hydrogen peroxide disinfectants had significantly higher bactericidal efficacies than quaternary ammonium chloride disinfectants. We also found that all tested disinfectants except for quaternary ammonium chloride disinfectants met and exceeded the EPA standard for bactericidal efficacy against biofilms. Conclusion:In general, bactericidal efficacy against biofilms differed by active ingredient. The efficacies of sodium hypochlorite and hydrogen peroxide disinfectants did not vary between strains, but there were significant differences between strains treated with quaternary ammonium chloride disinfectants.
journal_name
Antimicrob Resist Infect Controljournal_title
Antimicrobial resistance and infection controlauthors
Lineback CB,Nkemngong CA,Wu ST,Li X,Teska PJ,Oliver HFdoi
10.1186/s13756-018-0447-5subject
Has Abstractpub_date
2018-12-17 00:00:00pages
154issn
2047-2994pii
447journal_volume
7pub_type
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-016-0157-9
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章,多中心研究
doi:10.1186/s13756-018-0390-5
更新日期:2018-08-13 00:00:00
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doi:10.1186/s13756-019-0639-7
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-019-0566-7
更新日期:2019-07-08 00:00:00
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-017-0284-y
更新日期:2017-12-13 00:00:00
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/2047-2994-1-37
更新日期:2012-11-20 00:00:00
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/2047-2994-1-12
更新日期:2012-03-16 00:00:00
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-017-0249-1
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journal_title:Antimicrobial resistance and infection control
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/2047-2994-1-8
更新日期:2012-02-13 00:00:00
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-018-0299-z
更新日期:2018-01-26 00:00:00
abstract:Objective:Coagulase-negative staphylococci (CoNS) are one of the major opportunistic pathogens and the incidence of CoNS bacteraemia is increasing. However, most of the CoNS-positive blood cultures are contaminants rather than true CoNS bacteraemia. In order to minimize contamination, we defined true CoNS bacteraemia a...
journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-019-0523-5
更新日期:2019-04-24 00:00:00
abstract:BACKGROUND:Beta-lactam and quinolone antimicrobials are commonly used for treatment of infections caused by non-typhoidal Salmonella (NTS) and other pathogens. Resistance to these classes of antimicrobials has increased significantly in the recent years. However, little is known on the genetic basis of resistance to th...
journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-017-0171-6
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-020-00794-7
更新日期:2020-08-05 00:00:00
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-020-00853-z
更新日期:2020-12-01 00:00:00
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-015-0096-x
更新日期:2015-12-18 00:00:00
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-020-00802-w
更新日期:2020-08-17 00:00:00
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-016-0119-2
更新日期:2016-05-21 00:00:00
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/2047-2994-3-9
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-019-0658-4
更新日期:2019-12-04 00:00:00
abstract:BACKGROUND:Very low birthweight (VLBW) newborns on neonatal intensive care units (NICU) are at increased risk for developing central venous catheter-associated bloodstream infections (CVC BSI). In addition to the established intrinsic risk factors of VLBW newborns, it is still not clear which process and structure para...
journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/2047-2994-2-11
更新日期:2013-04-04 00:00:00
abstract::As emergence and spread of multi-drug resistant organisms (MDRO) requires a standardized preventive approach, we aimed to evaluate current MDRO admission screening practices in Swiss hospitals and to identify potential barriers impeding their implementation. In early 2018, all Swiss public and private healthcare insti...
journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-019-0479-5
更新日期:2019-02-13 00:00:00
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-016-0165-9
更新日期:2017-01-05 00:00:00
abstract:UNLABELLED: BACKGROUND:Antimicrobial stewardship has been promoted as a key strategy for coping with the problems of antimicrobial resistance and Clostridium difficile. Despite the current call for stewardship in community hospitals, including smaller community hospitals, practical examples of stewardship programs are...
journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/2047-2994-1-32
更新日期:2012-10-09 00:00:00
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-017-0273-1
更新日期:2017-11-14 00:00:00
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journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-019-0616-1
更新日期:2019-10-17 00:00:00
abstract:Background:Disinfectant products are often used on environmental surfaces (e.g. countertops, patient beds) and patient care equipment in healthcare facilities to help prevent the transmission of healthcare-associated infections. Ready-to-use (RTU) disinfectants in the form of pre-wetted towelettes are increasingly popu...
journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章
doi:10.1186/s13756-018-0416-z
更新日期:2018-10-11 00:00:00
abstract:OBJECTIVES:To determine the risk of SARS-CoV-2 transmission by aerosols, to provide evidence on the rational use of masks, and to discuss additional measures important for the protection of healthcare workers from COVID-19. METHODS:Literature review and expert opinion. SHORT CONCLUSION:SARS-CoV-2, the pathogen causin...
journal_title:Antimicrobial resistance and infection control
pub_type: 杂志文章,评审
doi:10.1186/s13756-020-00763-0
更新日期:2020-07-06 00:00:00