Hydrogen peroxide and sodium hypochlorite disinfectants are more effective against Staphylococcus aureus and Pseudomonas aeruginosa biofilms than quaternary ammonium compounds.

Abstract:

Background:Antimicrobial disinfectants are used as primary treatment options against pathogens on surfaces in healthcare facilities to help prevent healthcare associated infections (HAIs). On many surfaces, pathogenic microorganisms exist as biofilms and form an extracellular matrix that protects them from the antimicrobial effects of disinfectants. Disinfectants are used as all-purpose antimicrobials though very few specifically make biofilm efficacy claims. The objective of this study was to evaluate the efficacy of eight registered disinfectants (six registered by the Environmental Protection Agency and two products registered in by the European Chemical Agency) with general bactericidal claims, but currently no biofilm efficacy claims, against Staphylococcus aureus ATTC-6538 and Pseudomonas aeruginosa ATCC-15442 biofilms. We hypothesized that hydrogen peroxide and sodium hypochlorite disinfectant products would be more effective than quaternary ammonium chlorides. Methods:This study tested the bactericidal efficacy of eight registered disinfectant products against S. aureus ATCC-6538 and P. aeruginosa ATCC-15442 grown on glass coupons using a Center for Disease Control (CDC) biofilm reactor and EPA MLB SOP MB-19. Bactericidal efficacy was determined after treating coupons with disinfectants following standard EPA MLB SOP MB-20. Results:Overall, sodium hypochlorite and hydrogen peroxide disinfectants had significantly higher bactericidal efficacies than quaternary ammonium chloride disinfectants. We also found that all tested disinfectants except for quaternary ammonium chloride disinfectants met and exceeded the EPA standard for bactericidal efficacy against biofilms. Conclusion:In general, bactericidal efficacy against biofilms differed by active ingredient. The efficacies of sodium hypochlorite and hydrogen peroxide disinfectants did not vary between strains, but there were significant differences between strains treated with quaternary ammonium chloride disinfectants.

authors

Lineback CB,Nkemngong CA,Wu ST,Li X,Teska PJ,Oliver HF

doi

10.1186/s13756-018-0447-5

subject

Has Abstract

pub_date

2018-12-17 00:00:00

pages

154

issn

2047-2994

pii

447

journal_volume

7

pub_type

杂志文章
  • Using the best available data to estimate the cost of antimicrobial resistance: a systematic review.

    abstract:Background:Valuation of the economic cost of antimicrobial resistance (AMR) is important for decision making and should be estimated accurately. Highly variable or erroneous estimates may alarm policy makers and hospital administrators to act, but they also create confusion as to what the most reliable estimates are an...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章,meta分析

    doi:10.1186/s13756-019-0472-z

    authors: Wozniak TM,Barnsbee L,Lee XJ,Pacella RE

    更新日期:2019-02-01 00:00:00

  • Development of amoxicillin resistance in Escherichia coli after exposure to remnants of a non-related phagemid-containing E. coli: an exploratory study.

    abstract:OBJECTIVE:To determine the effect of exposure to remnants of a phagemid-containing E. coli, killed by treatment with a propanol-based hand rub, on antimicrobial resistance in E. coli isolates. METHODS:An in vitro model was developed in which a clinical E. coli isolate (EUR1) was exposed to remnants of an E. coli K-12 ...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-020-00708-7

    authors: Stohr JJJM,Kluytmans-van den Bergh MFQ,Verhulst CJMM,Rossen JWA,Kluytmans JAJW

    更新日期:2020-03-16 00:00:00

  • Optimizing antimicrobial prescribing: Are clinicians following national trends in methicillin-resistant staphylococcus aureus (MRSA) infections rather than local data when treating MRSA wound infections.

    abstract:BACKGROUND:Clinicians often prescribe antimicrobials for outpatient wound infections before culture results are known. Local or national MRSA rates may be considered when prescribing antimicrobials. If clinicians prescribe in response to national rather than local MRSA trends, prescribing may be improved by making loca...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/2047-2994-2-28

    authors: Schweizer ML,Perencevich EN,Eber MR,Cai X,Shardell MD,Braykov N,Laxminarayan R

    更新日期:2013-10-15 00:00:00

  • Individual units rather than entire hospital as the basis for improvement: the example of two Methicillin resistant Staphylococcus aureus cohort studies.

    abstract:UNLABELLED: BACKGROUND:Two MRSA surveillance components exist within the German national nosocomial infection surveillance system KISS: one for the whole hospital (i.e. only hospital based data and no rates for individual units) and one for ICU-based data (rates for each individual ICU). The objective of this study wa...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/2047-2994-1-8

    authors: Gastmeier P,Schwab F,Chaberny I,Geffers C

    更新日期:2012-02-13 00:00:00

  • Risk factors for surgical site infection after craniotomy: a prospective cohort study.

    abstract:Background:Although surgical site infection after craniotomy (SSI-CRAN) is a serious complication, risk factors for its development have not been well defined. We aim to identify the risk factors for developing SSI-CRAN in a large prospective cohort of adult patients undergoing craniotomy. Methods:A series of consecut...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-019-0525-3

    authors: Jiménez-Martínez E,Cuervo G,Hornero A,Ciercoles P,Gabarrós A,Cabellos C,Pelegrin I,García-Somoza D,Adamuz J,Carratalà J,Pujol M

    更新日期:2019-05-02 00:00:00

  • Surface area wiped, product type, and target strain impact bactericidal efficacy of ready-to-use disinfectant Towelettes.

    abstract:Background:Disinfectant products are often used on environmental surfaces (e.g. countertops, patient beds) and patient care equipment in healthcare facilities to help prevent the transmission of healthcare-associated infections. Ready-to-use (RTU) disinfectants in the form of pre-wetted towelettes are increasingly popu...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-018-0416-z

    authors: West AM,Nkemngong CA,Voorn MG,Wu T,Li X,Teska PJ,Oliver HF

    更新日期:2018-10-11 00:00:00

  • Adjustment of the MRSA Search and Destroy policy for outpatients in the Netherlands: a prospective cohort study with repeated prevalence measurements.

    abstract:BACKGROUND:In the Netherlands a successful MRSA Search and Destroy policy is applied in healthcare institutes. We determined the effect of an adjustment in the MRSA Search and Destroy policy for patients in the outpatient clinic on the MRSA transmission to health care workers (HCW). METHODS:In June 2008 an adjustment ...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/2047-2994-3-3

    authors: van Rijen MM,Kluytmans JA

    更新日期:2014-01-15 00:00:00

  • Risk of SARS-CoV-2 transmission by aerosols, the rational use of masks, and protection of healthcare workers from COVID-19.

    abstract:OBJECTIVES:To determine the risk of SARS-CoV-2 transmission by aerosols, to provide evidence on the rational use of masks, and to discuss additional measures important for the protection of healthcare workers from COVID-19. METHODS:Literature review and expert opinion. SHORT CONCLUSION:SARS-CoV-2, the pathogen causin...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章,评审

    doi:10.1186/s13756-020-00763-0

    authors: Sommerstein R,Fux CA,Vuichard-Gysin D,Abbas M,Marschall J,Balmelli C,Troillet N,Harbarth S,Schlegel M,Widmer A,Swissnoso.

    更新日期:2020-07-06 00:00:00

  • Prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in retail food in Singapore.

    abstract::We characterised 227 Staphylococcus aureus isolates from retail food and food handlers' gloves samples obtained through food surveillance and risk assessment studies between 2011 and 2014. Of 227 isolates, five (2.2%) were methicillin-resistant and belonged to sequence types ST80 (n = 3) and ST6 (n = 2). All five isol...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-017-0255-3

    authors: Aung KT,Hsu LY,Koh TH,Hapuarachchi HC,Chau ML,Gutiérrez RA,Ng LC

    更新日期:2017-09-08 00:00:00

  • Scenario-based simulation training for the WHO hand hygiene self-assessment framework.

    abstract::The WHO SAVE LIVES: Clean Your Hands global hand hygiene campaign, launched in 2009 and celebrated annually on the 5th of May, features specific calls to action seeking to increase engagement from stakeholders' collaborations in hand hygiene improvement. WHO calls on everyone to be inspired by the global movement towa...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-019-0511-9

    authors: Tartari E,Fankhauser C,Peters A,Sithole BL,Timurkaynak F,Masson-Roy S,Allegranzi B,Pires D,Pittet D

    更新日期:2019-03-28 00:00:00

  • Epidemiology and microbiology of Gram-positive bloodstream infections in a tertiary-care hospital in Beijing, China: a 6-year retrospective study.

    abstract:Background:Gram-positive bacterial bloodstream infections (BSIs) are serious diseases associated with high morbidity and mortality. The following study examines the incidence, clinical characteristics and microbiological features, drug resistance situations and mortality associated with Gram-positive BSIs at a large Ch...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-018-0398-x

    authors: Zhu Q,Yue Y,Zhu L,Cui J,Zhu M,Chen L,Yang Z,Liang Z

    更新日期:2018-09-03 00:00:00

  • Prolonged outbreak of clonal MDR Pseudomonas aeruginosa on an intensive care unit: contaminated sinks and contamination of ultra-filtrate bags as possible route of transmission?

    abstract:BACKGROUND:We report on an outbreak in a surgical, interdisciplinary intensive care unit (ICU) of a tertiary care hospital. We detected a cluster of ICU patients colonized or infected with multidrug-resistant Pseudomonas aeruginosa. We established an outbreak investigation team, performed an exploratory epidemiological...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-016-0157-9

    authors: Salm F,Deja M,Gastmeier P,Kola A,Hansen S,Behnke M,Gruhl D,Leistner R

    更新日期:2016-12-06 00:00:00

  • Nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) among undocumented migrants and uninsured legal residents in Amsterdam, the Netherlands: a cross-sectional study.

    abstract:BACKGROUND:Nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) is associated with an increased risk of infection. Colonization with MRSA is observed in < 1% of the general Dutch population. Increased risk for MRSA carriage is known to occur in several key groups, one of which is asylum seekers. However...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-020-00785-8

    authors: van Dulm E,Klok S,Boyd A,Joore IK,Prins M,van Dam AP,Tramper-Stranders GA,van Duijnhoven YTHP

    更新日期:2020-07-29 00:00:00

  • Practice of over-the-counter dispensary of antibiotics for childhood illnesses in Addis Ababa, Ethiopia: a simulated patient encounter study.

    abstract:Background:Dispensary and use of antibiotics without prescriptions from qualified providers is a common practice in countries with poor pharmaceutical regulations and where due focus is not given to rational use. This practice is a main factor for the spread of antimicrobial resistance due to its non-reliance on pre-tr...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s13756-019-0571-x

    authors: Koji EM,Gebretekle GB,Tekle TA

    更新日期:2019-07-16 00:00:00

  • The impact of staffing on central venous catheter-associated bloodstream infections in preterm neonates - results of nation-wide cohort study in Germany.

    abstract:BACKGROUND:Very low birthweight (VLBW) newborns on neonatal intensive care units (NICU) are at increased risk for developing central venous catheter-associated bloodstream infections (CVC BSI). In addition to the established intrinsic risk factors of VLBW newborns, it is still not clear which process and structure para...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/2047-2994-2-11

    authors: Leistner R,Thürnagel S,Schwab F,Piening B,Gastmeier P,Geffers C

    更新日期:2013-04-04 00:00:00

  • Antibiotic use on paediatric inpatients in a teaching hospital in the Gambia, a retrospective study.

    abstract:Background:Antibiotics are useful but increasing resistance is a major problem. Our objectives were to assess antibiotic use and microbiology testing in hospitalized children in the Gambia. Methods:We conducted a retrospective analysis of paediatric inpatient data at The Edward Francis Small Teaching Hospital in Banju...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-018-0380-7

    authors: Chaw PS,Schlinkmann KM,Raupach-Rosin H,Karch A,Pletz MW,Huebner J,Nyan O,Mikolajczyk R

    更新日期:2018-07-16 00:00:00

  • Implementation of a surgical unit-based safety programme in African hospitals: a multicentre qualitative study.

    abstract:Background:A Surgical Unit-based Safety Programme (SUSP) has been shown to improve perioperative prevention practices and to reduce surgical site infections (SSI). It is critical to understand the factors influencing the successful implementation of the SUSP approach in low- and middle-income settings. We undertook a q...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s13756-019-0541-3

    authors: Clack L,Willi U,Berenholtz S,Aiken AM,Allegranzi B,Sax H

    更新日期:2019-05-30 00:00:00

  • Evaluating risk factors for Clostridium difficile infection in adult and pediatric hematopoietic cell transplant recipients.

    abstract:BACKGROUND:Although hematopoietic cell transplant (HCT) recipients are routinely exposed to classic risk factors for Clostridium difficile infection (CDI), few studies have assessed CDI risk in these high-risk patients, and data are especially lacking for pediatric HCT recipients. We aimed to determine incidence and ri...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-015-0081-4

    authors: Boyle NM,Magaret A,Stednick Z,Morrison A,Butler-Wu S,Zerr D,Rogers K,Podczervinski S,Cheng A,Wald A,Pergam SA

    更新日期:2015-10-14 00:00:00

  • Will healthcare workers improve infection prevention and control behaviors as COVID-19 risk emerges and increases, in China?

    abstract:BACKGROUND:COVID-19 arise global attention since their first public reporting. Infection prevention and control (IPC) is critical to combat COVID-19, especially at the early stage of pandemic outbreak. This study aimed to measure level of healthcare workers' (HCW') self-reported IPC behaviors with the risk of COVID-19 ...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-020-00746-1

    authors: Lai X,Wang X,Yang Q,Xu X,Tang Y,Liu C,Tan L,Lai R,Wang H,Zhang X,Zhou Q,Chen H

    更新日期:2020-06-11 00:00:00

  • Hip and knee arthroplasty: quo vadis?

    abstract::Despite of the steady decrease of surgical site infection (SSI) over the last two decades, the incidence of SSI after hip and knee arthroplasty has recently surged. This may be explained by technical changes that may result in an increased risk of SSI, such as the broad implementation of fast track programs, and/or ea...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-015-0060-9

    authors: Ho J,Meis JF,Nabuurs-Franssen M,Voss A

    更新日期:2015-05-15 00:00:00

  • The use of typing methods and infection prevention measures to control a bullous impetigo outbreak on a neonatal ward.

    abstract:UNLABELLED: BACKGROUND:We describe an outbreak of Bullous Impetigo (BI), caused by a (methicillin susceptible, fusidic acid resistant) Staphylococcus aureus (SA) strain, spa-type t408, at the neonatal and gynaecology ward of the Jeroen Bosch hospital in the Netherlands, from March-November 2011. METHODS:We performed ...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/2047-2994-1-37

    authors: Koningstein M,Groen L,Geraats-Peters K,Lutgens S,Rietveld A,Jira P,Kluytmans J,de Greeff SC,Hermans M,Schneeberger PM

    更新日期:2012-11-20 00:00:00

  • The incidence of MRSA infections in the United States: is a more comprehensive tracking system needed?

    abstract::A review of epidemiological studies on the incidence of MRSA infections overtime was performed along with an analysis of data available for download from Hospital Compare (https://data.medicare.gov/data/hospital-compare). We found the estimations of the incidence of MRSA infections varied widely depending upon the typ...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-017-0193-0

    authors: Kavanagh KT,Abusalem S,Calderon LE

    更新日期:2017-04-07 00:00:00

  • The species distribution, antimicrobial resistance and risk factors for poor outcome of coagulase-negative staphylococci bacteraemia in China.

    abstract:Objective:Coagulase-negative staphylococci (CoNS) are one of the major opportunistic pathogens and the incidence of CoNS bacteraemia is increasing. However, most of the CoNS-positive blood cultures are contaminants rather than true CoNS bacteraemia. In order to minimize contamination, we defined true CoNS bacteraemia a...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-019-0523-5

    authors: Cui J,Liang Z,Mo Z,Zhang J

    更新日期:2019-04-24 00:00:00

  • Social media posts and online search behaviour as early-warning system for MRSA outbreaks.

    abstract:Background:Despite many preventive measures, outbreaks with multi-drug resistant micro-organisms (MDROs) still occur. Moreover, current alert systems from healthcare organizations have shortcomings due to delayed or incomplete notifications, which may amplify the spread of MDROs by introducing infected patients into a ...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-018-0359-4

    authors: van de Belt TH,van Stockum PT,Engelen LJLPG,Lancee J,Schrijver R,Rodríguez-Baño J,Tacconelli E,Saris K,van Gelder MMHJ,Voss A

    更新日期:2018-05-30 00:00:00

  • Mixed methods evaluation of the impact of a short term training program on sterile processing knowledge, practice, and attitude in three hospitals in Benin.

    abstract:Background:Proper sterile processing is fundamental to safe surgical practice and optimal patient outcomes. Sterile processing practices in low and middle-income countries often fall short of recommended standards. The impact of education and training on sterile processing practices in low and middle-income countries i...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-018-0312-6

    authors: Fast O,Fast C,Fast D,Veltjens S,Salami Z,White M

    更新日期:2018-02-13 00:00:00

  • Newest data on fluoroquinolone resistance mechanism of Shigella flexneri isolates in Jiangsu Province of China.

    abstract:BACKGROUND:To determine the prevalence, antimicrobial susceptibility patterns and related presence of mutations in quinolone resistance-determining region (QRDR) genes and plasmid-mediated quinolone resistance (PMQR) among Shigella flexneri isolates obtained from Jiangsu Province, China. METHODS:A total of 400 Shigell...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-017-0249-1

    authors: Qin T,Qian H,Fan W,Ma P,Zhou L,Dong C,Gu B,Huo X

    更新日期:2017-09-19 00:00:00

  • Why psychiatry is different - challenges and difficulties in managing a nosocomial outbreak of coronavirus disease (COVID-19) in hospital care.

    abstract:OBJECTIVE:Coronavirus disease (COVID-19) was officially declared a pandemic in March 2020. Many cases of COVID-19 are nosocomial, but to the best of our knowledge, no nosocomial outbreaks on psychiatric departments of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported in Europe. The differe...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/s13756-020-00853-z

    authors: Rovers JJE,van de Linde LS,Kenters N,Bisseling EM,Nieuwenhuijse DF,Oude Munnink BB,Voss A,Nabuurs-Franssen M

    更新日期:2020-12-01 00:00:00

  • Keeping PPE barriers in COVID-19 wards while doing proper auscultation.

    abstract::The emerging COVID-19 pandemic poses many difficulties to medical professionals. One of them is the need to use personal protective equipment (PPE) in order to protect themselves and their families, while not compromising their care. Physical examination is one of the cornerstones of medical assessment but parts of it...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 信件

    doi:10.1186/s13756-020-00854-y

    authors: Seidel E,Luski S,Ribak Y,Nama A,Saraya T,Nishiyama T,Oster Y,Nir-Paz R

    更新日期:2020-12-09 00:00:00

  • High proportion of healthcare-associated urinary tract infection in the absence of prior exposure to urinary catheter: a cross-sectional study.

    abstract:BACKGROUND:Exposure to urinary catheters is considered the most important risk factor for healthcare-associated urinary tract infection (UTI) and is associated with significant morbidity and substantial extra-costs. In this study, we assessed the impact of urinary catheterisation (UC) on symptomatic healthcare-associat...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/2047-2994-2-5

    authors: Uçkay I,Sax H,Gayet-Ageron A,Ruef C,Mühlemann K,Troillet N,Petignat C,Bernasconi E,Balmelli C,Widmer A,Boubaker K,Pittet D,Swiss-NOSO network.

    更新日期:2013-02-07 00:00:00

  • Changing epidemiology of infections due to extended spectrum beta-lactamase producing bacteria.

    abstract:BACKGROUND:Community-associated infections caused by extended-spectrum beta-lactamase (ESBL) producing bacteria are a growing concern. METHODS:Retrospective cohort study of clinical infections due to ESBL-producing bacteria requiring admission from 2006-2011 at a tertiary care academic medical center in Providence, RI...

    journal_title:Antimicrobial resistance and infection control

    pub_type: 杂志文章

    doi:10.1186/2047-2994-3-9

    authors: Kassakian SZ,Mermel LA

    更新日期:2014-03-25 00:00:00