Abstract:
BACKGROUND:Infections with soil-transmitted helminths and pathogenic intestinal protozoa pose a considerable public health burden, particularly in low- and middle-income countries, including Nepal. We assessed the extent of intestinal parasite infections among schoolchildren in two districts of Nepal and determined underlying risk factors. METHODS:A cross-sectional survey was conducted between March and May 2015 in the districts of Dolakha and Ramechhap, Nepal. A total of 708 children, aged 8-16 years from 16 purposively selected schools, were enrolled. Each child provided a single stool sample that was subjected to a suite of copro-microscopic diagnoses for intestinal protozoa and helminths. Drinking water samples from different sources at schools (n = 29), community places (n = 43) and households (n = 562) were analysed for contamination with thermotolerant coliforms (TTC). A questionnaire was administered to determine individual- and household-level risk factors of intestinal parasite infections. Self-reported symptoms were assessed and a clinical examination was undertaken by a physician. Haemoglobin was measured and used as a proxy for anaemia. Mixed logistic regression models were applied to investigate associations. RESULTS:The overall prevalence of intestinal parasite infections was 39.7%. Trichuris trichiura (30.9%), Giardia intestinalis (30.5%) and hookworm (30.2%) were the predominant intestinal parasite infections. Children from households lacking soap for handwashing were at higher odds of intestinal parasite infections than children who had soap [adjusted odds ratio (aOR) 1.81; 95% confidence interval (CI): 1.13-2.89; P = 0.01]. Children from households without freely roaming domestic animals showed lower odds of G. intestinalis compared to children from households with freely roaming animals (aOR 0.52; 95% CI: 0.33-0.83; P = 0.01). One out of three (31.0%) children suffered from fever and 22.4% had watery diarrhoea within a two-week recall period. Anaemia was diagnosed in 23.6% of the children. Water contamination with TTC showed no clear association with intestinal parasite infection. CONCLUSIONS:Intestinal parasites are common among schoolchildren in the two surveyed districts of Nepal. An important risk factor was lack of soap for handwashing. Our findings call for efforts to control intestinal parasite infection and emphasis should be placed on improvements in water, sanitation and hygiene interventions. TRIAL REGISTRATION:ISRCTN17968589 (date assigned: 17 July 2015).
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
Shrestha A,Schindler C,Odermatt P,Gerold J,Erismann S,Sharma S,Koju R,Utzinger J,Cissé Gdoi
10.1186/s13071-018-3105-0subject
Has Abstractpub_date
2018-09-29 00:00:00pages
532issue
1issn
1756-3305pii
10.1186/s13071-018-3105-0journal_volume
11pub_type
杂志文章abstract:BACKGROUND:Widespread deforestation occurring in the tropics is hypothesized to impact the transmission of vector-borne diseases (VBD). Predicting how environmental changes will impact VBD transmission is dependent on understanding the ecology and behaviour of potential vector species outside of domestic settings. Howe...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-2926-1
更新日期:2018-06-14 00:00:00
abstract:BACKGROUND:Knowledge of the potential vector role of Culicidae mosquitoes in Germany is very scanty, and until recently it was generally assumed that they are not involved in the transmission of anthroponotic or zoonotic pathogens in this country. However, anticipated changes in the course of global warming and globali...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-5-14
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journal_title:Parasites & vectors
pub_type: 杂志文章
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更新日期:2015-05-14 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-017-2283-5
更新日期:2017-07-18 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
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更新日期:2021-01-19 00:00:00
abstract::The Companion Vector-Borne Diseases (CVBD) World Forum is a working group of leading international experts who meet annually to evaluate current scientific findings and future trends concerning the distribution, pathogenesis, clinical presentation, diagnosis and prevention of vector-borne infections of dogs and cats. ...
journal_title:Parasites & vectors
pub_type: 信件
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journal_title:Parasites & vectors
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journal_title:Parasites & vectors
pub_type: 杂志文章
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journal_title:Parasites & vectors
pub_type: 杂志文章
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journal_title:Parasites & vectors
pub_type: 杂志文章
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journal_title:Parasites & vectors
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journal_title:Parasites & vectors
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更新日期:2012-01-10 00:00:00
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journal_title:Parasites & vectors
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journal_title:Parasites & vectors
pub_type: 杂志文章,随机对照试验
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更新日期:2014-07-29 00:00:00
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journal_title:Parasites & vectors
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更新日期:2014-12-16 00:00:00
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journal_title:Parasites & vectors
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journal_title:Parasites & vectors
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journal_title:Parasites & vectors
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journal_title:Parasites & vectors
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journal_title:Parasites & vectors
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journal_title:Parasites & vectors
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journal_title:Parasites & vectors
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更新日期:2015-02-22 00:00:00
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journal_title:Parasites & vectors
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更新日期:2015-10-08 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
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更新日期:2015-02-24 00:00:00
abstract:BACKGROUND:Feline babesiosis, sporadically reported from various countries, is of major clinical significance in South Africa, particularly in certain coastal areas. Babesia felis, B. leo, B. lengau and B. microti have been reported from domestic cats in South Africa. Blood specimens from domestic cats (n = 18) showing...
journal_title:Parasites & vectors
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更新日期:2019-03-26 00:00:00
abstract:BACKGROUND:Several studies were carried out in experimental hut station in areas surrounding the city of Bouaké, after the crisis in Côte d'Ivoire. They reported increasing resistance levels to insecticide for malaria transmiting mosquitoes. The present work aims to evaluate the current resistance level of An. gambiae ...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-2702-2
更新日期:2018-03-02 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-017-2060-5
更新日期:2017-04-21 00:00:00
abstract:BACKGROUND:The East Route Project (ERP) of the South-to-North Water Diversion Project (SNWDP) stretches across schistosomiasis endemic and non-endemic areas in China, which may lead to the dispersal of Oncomelania hupensis, the intermediate host of Schistosoma japonicum, from permissive areas along the Yangtze River Ba...
journal_title:Parasites & vectors
pub_type: 杂志文章
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更新日期:2020-03-19 00:00:00