Abstract：
Background:A substantial portion of Clostridium difficile infection (CDI) cases occur in communities, and community-onset CDI (CO-CDI) can lead to serious complications including mortality. This study aimed to identify the risk factors for a poor outcome in CO-CDI. Methods:We performed a retrospective review of all inpatients with CDI, in a 1300-bed tertiary-care hospital in Korea, from 2008 through 2015. CO-CDI was defined as CDI occurring within 48 h of admission. Poor outcome was defined as follows: 1) all-cause 30-day mortality, 2) in-hospital mortality, or 3) surgery due to CDI. Results:Of a total 1256 CDIs occurring over 8 years, 152 (12.1%) cases were classified as CO-CDI and 23 (15.1%) had a poor outcome, including 22 (14.5%) cases of mortality and 2 (1.3%) cases of surgery. Patients with a poor outcome had a higher mean age than those without a poor outcome (75.8 vs. 69.6 years, p = 0.03). The proportion of men and prior proton pump inhibitor (PPI) use were significantly higher in the poor outcome group (65.2% vs. 41.9%, p = 0.04; 39.1% vs. 17.6%, p = 0.02, respectively). Multivariate binary logistic model showed that PPI use and anemia (hemoglobin < 10 g/dL) at presentation were significantly associated with a poor outcome (adjusted odds ratio [aOR], 3.76; 95% confidence interval [95CI], 1.26-11.21, aOR, 4.67; 95CI, 1.52-14.34, respectively). Conclusions:Clinicians should not only be aware of the possibility of CDI in the community setting but also pay more attention to PPI-using elderly patients with anemia in consideration of a poor outcome.
journal_name
Antimicrob Resist Infect Controljournal_title
Antimicrobial resistance and infection controlauthors
Lee E,Song KH,Bae JY,Yoon D,Hwang JH,Choe PG,Park WB,Bang JH,Kim ES,Park SW,Kim NJ,Oh MD,Kim HBdoi
10.1186/s13756-018-0365-6subject
Has Abstractpub_date
2018-06-15 00:00:00pages
75issn
2047-2994pii
365journal_volume
7pub_type
杂志文章abstract：Background:The methicillin-resistant clone Staphylococcus capitis NRCS-A, involved in sepsis in neonatal intensive care units (NICUs) worldwide, is able to persist and spread in NICUs, suggesting the presence of reservoirs inside each setting. The purpose of the present study was to identify these reservoirs and to inv...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-019-0616-1
更新日期：2019-10-17 00:00:00
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journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-017-0273-1
更新日期：2017-11-14 00:00:00
abstract：BACKGROUND:Preoperative skin antisepsis is an essential component of safe surgery. However, it is unclear how many antiseptic paints are needed to eliminate bacteria prior to incision. This study compared microbial skin counts after two and three antiseptic paints. METHODS:We conducted a prospective cohort study in no...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-020-00780-z
更新日期：2020-07-31 00:00:00
abstract：UNLABELLED: BACKGROUND:Vancomycin-resistant isolates of E. faecalis and E. faecium are of special concern and patients at risk of acquiring a VRE colonization/infection include also intensively-cared neonates. We describe here an ongoing high prevalence of VanB type E. faecium in a neonatal ICU hardly to identify by r...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/2047-2994-1-21
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journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-016-0157-9
更新日期：2016-12-06 00:00:00
abstract：:Despite improvements in hospital infection prevention and control, healthcare associated infections (HAIs) remain a challenge with significant patient morbidity, mortality, and cost for the healthcare system. In this review, we use a One Health framework (human, animal, and environmental health) to explain the epidemi...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章,评审
doi：10.1186/s13756-020-00737-2
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVE:To determine the effect of exposure to remnants of a phagemid-containing E. coli, killed by treatment with a propanol-based hand rub, on antimicrobial resistance in E. coli isolates. METHODS:An in vitro model was developed in which a clinical E. coli isolate (EUR1) was exposed to remnants of an E. coli K-12 ...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-020-00708-7
更新日期：2020-03-16 00:00:00
abstract：Background:This is the first review of literature and synthesis of data on community onset methicillin resistant Staphylococcus aureus (CO-MRSA) infections in Australia. Incidence of CO-MRSA varies considerably in Australia, depending on geographic and demographic factors. Methods:Data for the rates of MRSA infections...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-019-0485-7
更新日期：2019-02-12 00:00:00
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journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-017-0250-8
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journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-017-0283-z
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pub_type： 杂志文章
doi：10.1186/s13756-018-0337-x
更新日期：2018-04-03 00:00:00
abstract：Background:A Surgical Unit-based Safety Programme (SUSP) has been shown to improve perioperative prevention practices and to reduce surgical site infections (SSI). It is critical to understand the factors influencing the successful implementation of the SUSP approach in low- and middle-income settings. We undertook a q...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章,多中心研究
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更新日期：2019-05-30 00:00:00
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journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-017-0171-6
更新日期：2017-01-17 00:00:00
abstract：BACKGROUND:Healthcare-associated infections (HAI) especially outbreaks of multi-drug-resistant organisms within hospitals are recognized as a major contributor to morbidity and mortality of hospitalized patients. The healthcare environment can act as an amplifier of HAI during outbreaks. The risk of acquiring HAI are 2...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章,评审
doi：10.1186/s13756-020-00747-0
更新日期：2020-06-09 00:00:00
abstract：OBJECTIVE:To describe the containment of a widespread silent outbreak of vancomycin-resistant Enterococcus faecium (VRE-fm) in the Tel-Aviv Medical Center (TASMC) neonatal intensive care unit (NICU). METHODS:Setting - an NICU, participants - 49 cases of VRE-fm-colonized neonatal inpatients. RESULTS:A newborn was tran...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-020-00755-0
更新日期：2020-06-16 00:00:00
abstract：BACKGROUND:The burden of healthcare-associated infection (HAI) is 2 to 18 times higher in developing countries. However, few data are available regarding infection prevention and control (IPC) process indicators in these countries. We evaluated hand hygiene (HH) facilities and compliance amongst healthcare workers (HCW...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-020-0693-1
更新日期：2020-02-11 00:00:00
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journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-017-0292-y
更新日期：2018-01-06 00:00:00
abstract：OBJECTIVES:Surgical antibiotic prophylaxis (SAP) represents a major indication of antibiotic consumption worldwide. The present study aims to report the results of an enabling, long-term AMS intervention conducted between 2013 and 2019 on an Italian University Hospital performing more than 40.000 surgical interventions...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-020-00814-6
更新日期：2020-10-26 00:00:00
abstract：Objective:To describe the epidemiology of carbapenem-resistant Enterobacteriaceae (CRE) healthcare-associated infections (HAI) in Egyptian hospitals reporting to the national HAI surveillance system. Methods:Design: Descriptive analysis of CRE HAIs and retrospective observational cohort study using national HAI survei...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-019-0639-7
更新日期：2020-01-03 00:00:00
abstract：BACKGROUND:Due to limited therapeutic options and their association with high mortality and morbidity, carbapenem-non-susceptible Acinetobacter spp. (CNA) are of significant public health importance. This study aimed to describe current epidemiological trends of CNA proportions in Europe and to identify factors that ar...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-020-00750-5
更新日期：2020-06-19 00:00:00
abstract：BACKGROUND:Pseudomonas endocarditis is exceedingly rare, especially in patients without predisposing risks. We present such a case that included unexpected switches in antibacterial resistance profiles in two Pseudomonas aeruginosa (PA) strains with the same whole-genome sequence. The case also involved diagnostic and ...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-017-0245-5
更新日期：2017-08-29 00:00:00
abstract：BACKGROUND:Surgical site infections (SSI) are one of the most common healthcare associated infections in the low-middle income countries. Data on incidence and risk factors for SSI following surgeries in general and Obstetric and Gynecological surgeries in particular are scare. This study set out to identify risk facto...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-017-0223-y
更新日期：2017-06-14 00:00:00
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journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-018-0380-7
更新日期：2018-07-16 00:00:00
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journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-019-0658-4
更新日期：2019-12-04 00:00:00
abstract：BACKGROUND:The extent of the occurrence of the plasmid-encoded colistin resistance genes mcr-1 and mcr-2 among humans is currently sparsely studied in Western Europe. OBJECTIVES:To determine the occurrence of MCR-producing Enterobacteriaceae in fecal samples of healthy humans with high occupational exposure to food an...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-017-0186-z
更新日期：2017-03-14 00:00:00
abstract：Background:Escherichia coli is one of the most common strains of extended-spectrum β-lactam (ESBL)-producing bacteria, and the prevention and treatment of ESBL-producing E. coli infections is an ongoing challenge. The clinical characteristics and outcomes of ESBL-producing E. coli bacteremia in non-transplant patients ...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-019-0599-y
更新日期：2019-08-27 00:00:00
abstract：BACKGROUND:Very low birthweight (VLBW) newborns on neonatal intensive care units (NICU) are at increased risk for developing central venous catheter-associated bloodstream infections (CVC BSI). In addition to the established intrinsic risk factors of VLBW newborns, it is still not clear which process and structure para...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/2047-2994-2-11
更新日期：2013-04-04 00:00:00
abstract：Purpose:This study aims to determine the effectiveness of an Antimicrobial Stewardship Program based on a Clinical Pathway (CP) to improve appropriateness in perioperative antibiotic prophylaxis (PAP). Materials and methods:This pre-post quasi-experimental study was conducted in a 12 month period (six months before an...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-019-0464-z
更新日期：2019-01-15 00:00:00
abstract：BACKGROUND:Candidemia is a common cause of nosocomial bloodstream infections, resulting in high morbidity and mortality. This study was conducted to describe the epidemiology, species distribution, antifungal susceptibility patterns and outcomes of candidemia in a large regional tertiary referral hospital. METHODS:A r...
journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-017-0184-1
更新日期：2017-03-11 00:00:00
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journal_title：Antimicrobial resistance and infection control
pub_type： 杂志文章
doi：10.1186/s13756-018-0447-5
更新日期：2018-12-17 00:00:00
