A case of respiratory toxigenic diphtheria: contact tracing results and considerations following a 30-year disease-free interval, Catalonia, Spain, 2015.

Abstract:

:In May 2015, following a 30-year diphtheria-free interval in Catalonia, an unvaccinated 6-year-old child was diagnosed with diphtheria caused by toxigenic Corynebacterium diphtheriae. After a difficult search for equine-derived diphtheria antitoxin (DAT), the child received the DAT 4 days later but died at the end of June. Two hundred and seventeen contacts were identified in relation to the index case, and their vaccination statuses were analysed, updated and completed. Of these, 140 contacts underwent physical examination and throat swabs were taken from them for analysis. Results were positive for toxigenic C. diphtheriae in 10 contacts; nine were asymptomatic vaccinated children who had been in contact with the index case and one was a parent of one of the nine children. Active surveillance of the 217 contacts was initiated by healthcare workers from hospitals and primary healthcare centres, together with public health epidemiological support. Lack of availability of DAT was an issue in our case. Such lack could be circumvented by the implementation of an international fast-track procedure to obtain it in a timely manner. Maintaining primary vaccination coverage for children and increasing booster-dose immunisation against diphtheria in the adult population is of key importance.

journal_name

Euro Surveill

authors

Jané M,Vidal MJ,Camps N,Campins M,Martínez A,Balcells J,Martin-Gomez MT,Bassets G,Herrera-León S,Foguet A,Maresma M,Follia N,Uriona S,Pumarola T

doi

10.2807/1560-7917.ES.2018.23.13.17-00183

subject

Has Abstract

pub_date

2018-03-01 00:00:00

issue

13

eissn

1025-496X

issn

1560-7917

journal_volume

23

pub_type

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