Evidence From Web-Based Dietary Search Patterns to the Role of B12 Deficiency in Non-Specific Chronic Pain: A Large-Scale Observational Study.

Abstract:

BACKGROUND:Profound vitamin B12 deficiency is a known cause of disease, but the role of low or intermediate levels of B12 in the development of neuropathy and other neuropsychiatric symptoms, as well as the relationship between eating meat and B12 levels, is unclear. OBJECTIVE:The objective of our study was to investigate the role of low or intermediate levels of B12 in the development of neuropathy and other neuropsychiatric symptoms. METHODS:We used food-related Internet search patterns from a sample of 8.5 million people based in the US as a proxy for B12 intake and correlated these searches with Internet searches related to possible effects of B12 deficiency. RESULTS:Food-related search patterns were highly correlated with known consumption and food-related searches (ρ=.69). Awareness of B12 deficiency was associated with a higher consumption of B12-rich foods and with queries for B12 supplements. Searches for terms related to neurological disorders were correlated with searches for B12-poor foods, in contrast with control terms. Popular medicines, those having fewer indications, and those which are predominantly used to treat pain, were more strongly correlated with the ability to predict neuropathic pain queries using the B12 contents of food. CONCLUSIONS:Our findings show that Internet search patterns are a useful way of investigating health questions in large populations, and suggest that low B12 intake may be associated with a broader spectrum of neurological disorders than previously thought.

journal_name

J Med Internet Res

authors

Giat E,Yom-Tov E

doi

10.2196/jmir.8667

subject

Has Abstract

pub_date

2018-01-05 00:00:00

pages

e4

issue

1

eissn

1439-4456

issn

1438-8871

pii

v20i1e4

journal_volume

20

pub_type

杂志文章
  • One Digital Health: a unified framework for future health ecosystems.

    abstract::One Digital Health is a proposed unified structure. The conceptual framework of the One Digital Health Steering Wheel is built around two keys (ie, One Health and digital health), three perspectives (ie, individual health and well-being, population and society, and ecosystem), and five dimensions (ie, citizens' engage...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/22189

    authors: Benis A,Tamburis O,Chronaki C,Moen A

    更新日期:2021-01-24 00:00:00

  • Impact of Illness on Electronic Health Use (The Seventh Tromsø Study - Part 2): Population-Based Questionnaire Study.

    abstract:BACKGROUND:Patients who suffer from different diseases may use different electronic health (eHealth) resources. Thus, those who plan eHealth interventions should take into account which eHealth resources are used most frequently by patients that suffer from different diseases. OBJECTIVE:The aim of this study was to un...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/13116

    authors: Marco-Ruiz L,Wynn R,Oyeyemi SO,Budrionis A,Yigzaw KY,Bellika JG

    更新日期:2020-03-05 00:00:00

  • Developing a Hypothetical Implementation Framework of Expectations for Monitoring Early Signs of Psychosis Relapse Using a Mobile App: Qualitative Study.

    abstract:BACKGROUND:Relapse is a common experience for people diagnosed with psychosis, which is associated with increased service costs and profound personal and familial distress. EMPOWER (Early signs Monitoring to Prevent relapse in psychosis and prOmote Well-being, Engagement, and Recovery) is a peer worker-supported digita...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/14366

    authors: Allan S,Bradstreet S,Mcleod H,Farhall J,Lambrou M,Gleeson J,Clark A,EMPOWER Group.,Gumley A

    更新日期:2019-10-24 00:00:00

  • Effects, Adherence, and Therapists' Perceptions of Web- and Mobile-Supported Group Therapy for Depression: Mixed-Methods Study.

    abstract:BACKGROUND:Blended group therapy (bGT) has been investigated a several times for anxiety and depression, but information on patients' adherence to and therapists' perception of the novel format is nonexistent. Furthermore, many studies investigated mainly female and highly educated populations, limiting the validity of...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/11860

    authors: Schuster R,Kalthoff I,Walther A,Köhldorfer L,Partinger E,Berger T,Laireiter AR

    更新日期:2019-04-28 00:00:00

  • Sources of traffic and visitors' preferences regarding online public reports of quality: web analytics and online survey results.

    abstract:BACKGROUND:In the context of the Affordable Care Act, there is extensive emphasis on making provider quality transparent and publicly available. Online public reports of quality exist, but little is known about how visitors find reports or about their purpose in visiting. OBJECTIVE:To address this gap, we gathered web...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/jmir.3637

    authors: Bardach NS,Hibbard JH,Greaves F,Dudley RA

    更新日期:2015-05-01 00:00:00

  • Demographic and Indication-Specific Characteristics Have Limited Association With Social Network Engagement: Evidence From 24,954 Members of Four Health Care Support Groups.

    abstract:BACKGROUND:Digital health social networks (DHSNs) are widespread, and the consensus is that they contribute to wellness by offering social support and knowledge sharing. The success of a DHSN is based on the number of participants and their consistent creation of externalities through the generation of new content. To ...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章,多中心研究

    doi:10.2196/jmir.6330

    authors: van Mierlo T,Li X,Hyatt D,Ching AT

    更新日期:2017-02-17 00:00:00

  • Fifteen Challenges in Establishing a Multidisciplinary Research Program on eHealth Research in a University Setting: A Case Study.

    abstract:BACKGROUND:U-CARE is a multidisciplinary eHealth research program that involves the disciplines of caring science, clinical psychology, health economics, information systems, and medical science. It was set up from scratch in a university setting in 2010, funded by a governmental initiative. While establishing the rese...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/jmir.7310

    authors: Grönqvist H,Olsson EMG,Johansson B,Held C,Sjöström J,Lindahl Norberg A,Hovén E,Sanderman R,van Achterberg T,von Essen L

    更新日期:2017-05-23 00:00:00

  • "If I Were Nick": Men's Responses to an Interactive Video Drama Series to Support Smoking Cessation.

    abstract:BACKGROUND:Men continue to smoke in greater numbers than women; however, few interventions have been developed and tested to support men's cessation. Men tend to rely on quitting strategies associated with stereotypical manliness, such as willpower, stoicism, and independence, but they may lack the self-efficacy skills...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/jmir.4491

    authors: Bottorff JL,Sarbit G,Oliffe JL,Kelly MT,Lohan M,Stolp S,Sharp P

    更新日期:2015-08-10 00:00:00

  • The need for online information on the economic consequences of cancer diagnosis, treatment, and survivorship.

    abstract::The Internet is commonly used to provide treatment information to patients diagnosed with cancer. Notably missing from the existing websites is information on the cost of cancer care in terms of medical costs to the patient and work-related consequences. The purpose of this paper is to describe what is known about the...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/jmir.7.3.e29

    authors: Bradley CJ

    更新日期:2005-07-01 00:00:00

  • Using Social Media to Target Cancer Prevention in Young Adults: Viewpoint.

    abstract::Focusing on primary cancer prevention can reduce its incidence. Changing health behaviors is critical to cancer prevention. Modifiable cancer risk factors include lifestyle behaviors related to vaccination, physical activity, weight control and maintenance, alcohol consumption, and tobacco use. These health habits are...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/jmir.8882

    authors: Sarkar U,Le GM,Lyles CR,Ramo D,Linos E,Bibbins-Domingo K

    更新日期:2018-06-05 00:00:00

  • Evaluation of a Web-Based E-Learning Platform for Brief Motivational Interviewing by Nurses in Cardiovascular Care: A Pilot Study.

    abstract:BACKGROUND:Brief motivational interviewing (MI) can contribute to reductions in morbidity and mortality related to coronary artery disease, through health behavior change. Brief MI, unlike more intensive interventions, was proposed to meet the needs of clinicians with little spare time. While the provision of face-to-f...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/jmir.6298

    authors: Fontaine G,Cossette S,Heppell S,Boyer L,Mailhot T,Simard MJ,Tanguay JF

    更新日期:2016-08-18 00:00:00

  • Efficacy of quality criteria to identify potentially harmful information: a cross-sectional survey of complementary and alternative medicine web sites.

    abstract:BACKGROUND:Many users search the Internet for answers to health questions. Complementary and alternative medicine (CAM) is a particularly common search topic. Because many CAM therapies do not require a clinician's prescription, false or misleading CAM information may be more dangerous than information about traditiona...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/jmir.6.2.e21

    authors: Walji M,Sagaram S,Sagaram D,Meric-Bernstam F,Johnson C,Mirza NQ,Bernstam EV

    更新日期:2004-06-29 00:00:00

  • Understanding Monitoring Technologies for Adults With Pain: Systematic Literature Review.

    abstract:BACKGROUND:Monitoring of patients may decrease treatment costs and improve quality of care. Pain is the most common health problem that people seek help for in hospitals. Therefore, monitoring patients with pain may have significant impact in improving treatment. Several studies have studied factors affecting pain; how...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章,评审

    doi:10.2196/jmir.7279

    authors: Rodríguez I,Herskovic V,Gerea C,Fuentes C,Rossel PO,Marques M,Campos M

    更新日期:2017-10-27 00:00:00

  • Rates, Delays, and Completeness of General Practitioners' Responses to a Postal Versus Web-Based Survey: A Randomized Trial.

    abstract:BACKGROUND:Web-based surveys have become a new and popular method for collecting data, but only a few studies have directly compared postal and Web-based surveys among physicians, and none to our knowledge among general practitioners (GPs). OBJECTIVE:Our aim is to compare two modes of survey delivery (postal and Web-b...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章,随机对照试验

    doi:10.2196/jmir.6308

    authors: Sebo P,Maisonneuve H,Cerutti B,Fournier JP,Senn N,Haller DM

    更新日期:2017-03-22 00:00:00

  • No increase in response rate by adding a web response option to a postal population survey: a randomized trial.

    abstract:BACKGROUND:There is substantial interest in use of the Internet for surveys, but there have been few health-oriented, large, randomized trials of general population surveys on the Internet. It is unclear whether providing the option to respond via Internet increases the response rate, and to what degree the results wil...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章,随机对照试验

    doi:10.2196/jmir.9.5.e40

    authors: Brøgger J,Nystad W,Cappelen I,Bakke P

    更新日期:2007-12-31 00:00:00

  • The effects on health behavior and health outcomes of Internet-based asynchronous communication between health providers and patients with a chronic condition: a systematic review.

    abstract:BACKGROUND:In support of professional practice, asynchronous communication between the patient and the provider is implemented separately or in combination with Internet-based self-management interventions. This interaction occurs primarily through electronic messaging or discussion boards. There is little evidence as ...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章,评审

    doi:10.2196/jmir.3000

    authors: de Jong CC,Ros WJ,Schrijvers G

    更新日期:2014-01-16 00:00:00

  • Interdisciplinary Online Hackathons as an Approach to Combat the COVID-19 Pandemic: Case Study.

    abstract:BACKGROUND:The COVID-19 outbreak has affected the lives of millions of people by causing a dramatic impact on several healthcare systems and the global economy. This devastating pandemic has brought communities across the globe to work on this issue in an unprecedented manner. OBJECTIVE:This case study describes the s...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/25283

    authors: Braune K,de Rojas PD,Hofferbert J,Valera Sosa A,Lebedev A,Balzer F,Thun S,Lieber S,Kirchberger V,Poncette AS

    更新日期:2021-01-16 00:00:00

  • Using the Internet for surveys and health research.

    abstract::This paper concerns the use of the Internet in the research process, from identifying research issues through qualitative research, through using the Web for surveys and clinical trials, to pre-publishing and publishing research results. Material published on the Internet may be a valuable resource for researchers des...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章,评审

    doi:10.2196/jmir.4.2.e13

    authors: Eysenbach G,Wyatt J

    更新日期:2002-04-01 00:00:00

  • The Messages Presented in Electronic Cigarette-Related Social Media Promotions and Discussion: Scoping Review.

    abstract:BACKGROUND:There has been a rapid rise in the popularity of electronic cigarettes (e-cigarettes) over the last decade, with growth predicted to continue. The uptake of these devices has escalated despite inconclusive evidence of their efficacy as a smoking cessation device and unknown long-term health consequences. As ...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章,评审

    doi:10.2196/11953

    authors: McCausland K,Maycock B,Leaver T,Jancey J

    更新日期:2019-02-05 00:00:00

  • Application of an Adaptive, Digital, Game-Based Approach for Cognitive Assessment in Multiple Sclerosis: Observational Study.

    abstract:BACKGROUND:Cognitive impairment is one of the most debilitating manifestations of multiple sclerosis. Currently, the assessment of cognition relies on a time-consuming and extensive neuropsychological examination, which is only available in some centers. OBJECTIVE:To enable simpler, more accessible cognitive screening...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/24356

    authors: Hsu WY,Rowles W,Anguera JA,Zhao C,Anderson A,Alexander A,Sacco S,Henry R,Gazzaley A,Bove R

    更新日期:2021-01-20 00:00:00

  • Internet-based early intervention to prevent posttraumatic stress disorder in injury patients: randomized controlled trial.

    abstract:BACKGROUND:Posttraumatic stress disorder (PTSD) develops in 10-20% of injury patients. We developed a novel, self-guided Internet-based intervention (called Trauma TIPS) based on techniques from cognitive behavioral therapy (CBT) to prevent the onset of PTSD symptoms. OBJECTIVE:To determine whether Trauma TIPS is effe...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章,随机对照试验

    doi:10.2196/jmir.2460

    authors: Mouthaan J,Sijbrandij M,de Vries GJ,Reitsma JB,van de Schoot R,Goslings JC,Luitse JS,Bakker FC,Gersons BP,Olff M

    更新日期:2013-08-13 00:00:00

  • Can an Internet-based health risk assessment highlight problems of heart disease risk factor awareness? A cross-sectional analysis.

    abstract:BACKGROUND:Health risk assessments are becoming more popular as a tool to conveniently and effectively reach community-dwelling adults who may be at risk for serious chronic conditions such as coronary heart disease (CHD). The use of such instruments to improve adults' risk factor awareness and concordance with clinica...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/jmir.2369

    authors: Dickerson JB,McNeal CJ,Tsai G,Rivera CM,Smith ML,Ohsfeldt RL,Ory MG

    更新日期:2014-04-18 00:00:00

  • Development and Efficacy of an Electronic, Culturally Adapted Lifestyle Counseling Tool for Improving Diabetes-Related Dietary Knowledge: Randomized Controlled Trial Among Ethnic Minority Adults With Type 2 Diabetes Mellitus.

    abstract:BACKGROUND:Ethnic minority populations exhibit disproportionately high rates of type 2 diabetes mellitus (T2DM). Electronic health tools have the potential to facilitate the cultural adaptation and tailoring of T2DM education to improve the knowledge and management of diabetes mellitus (DM). OBJECTIVE:This study aimed...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章,随机对照试验

    doi:10.2196/13674

    authors: Abu-Saad K,Murad H,Barid R,Olmer L,Ziv A,Younis-Zeidan N,Kaufman-Shriqui V,Gillon-Keren M,Rigler S,Berchenko Y,Kalter-Leibovici O

    更新日期:2019-10-16 00:00:00

  • Cost-effectiveness and cost-utility of Internet-based computer tailoring for smoking cessation.

    abstract:BACKGROUND:Although effective smoking cessation interventions exist, information is limited about their cost-effectiveness and cost-utility. OBJECTIVE:To assess the cost-effectiveness and cost-utility of an Internet-based multiple computer-tailored smoking cessation program and tailored counseling by practice nurses w...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章,随机对照试验

    doi:10.2196/jmir.2059

    authors: Smit ES,Evers SM,de Vries H,Hoving C

    更新日期:2013-03-14 00:00:00

  • A Peer-Led, Social Media-Delivered, Safer Sex Intervention for Chinese College Students: Randomized Controlled Trial.

    abstract:BACKGROUND:The peer-led, social media-delivered intervention is an emerging method in sexual health promotion. However, no research has yet investigated its effectiveness as compared with other online channels or in an Asian population. OBJECTIVE:The objective of this study is to compare a peer-led, social media-deliv...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章,随机对照试验

    doi:10.2196/jmir.7403

    authors: Sun WH,Wong CKH,Wong WCW

    更新日期:2017-08-09 00:00:00

  • Improving physician performance through Internet-based interventions: who will participate?

    abstract:BACKGROUND:The availability of Internet-based continuing medical education is rapidly increasing, but little is known about recruitment of physicians to these interventions. OBJECTIVE:The purpose of this study was to examine predictors of physician participation in an Internet intervention designed to increase screeni...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/jmir.7.4.e48

    authors: Wall TC,Mian MA,Ray MN,Casebeer L,Collins BC,Kiefe CI,Weissman N,Allison JJ

    更新日期:2005-09-02 00:00:00

  • Building a transnational biosurveillance network using semantic web technologies: requirements, design, and preliminary evaluation.

    abstract:BACKGROUND:Antimicrobial resistance has reached globally alarming levels and is becoming a major public health threat. Lack of efficacious antimicrobial resistance surveillance systems was identified as one of the causes of increasing resistance, due to the lag time between new resistances and alerts to care providers....

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/jmir.2043

    authors: Teodoro D,Pasche E,Gobeill J,Emonet S,Ruch P,Lovis C

    更新日期:2012-05-29 00:00:00

  • Smartphones as multimodal communication devices to facilitate clinical knowledge processes: randomized controlled trial.

    abstract:BACKGROUND:Despite the widespread use and advancements of mobile technology that facilitate rich communication modes, there is little evidence demonstrating the value of smartphones for effective interclinician communication and knowledge processes. OBJECTIVE:The objective of this study was to determine the effects of...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章,随机对照试验

    doi:10.2196/jmir.2758

    authors: Pimmer C,Mateescu M,Zahn C,Genewein U

    更新日期:2013-11-27 00:00:00

  • Persuasive system design does matter: a systematic review of adherence to web-based interventions.

    abstract:BACKGROUND:Although web-based interventions for promoting health and health-related behavior can be effective, poor adherence is a common issue that needs to be addressed. Technology as a means to communicate the content in web-based interventions has been neglected in research. Indeed, technology is often seen as a bl...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章,评审

    doi:10.2196/jmir.2104

    authors: Kelders SM,Kok RN,Ossebaard HC,Van Gemert-Pijnen JE

    更新日期:2012-11-14 00:00:00

  • Validation of an Independent Web-Based Tool for Measuring Visual Acuity and Refractive Error (the Manifest versus Online Refractive Evaluation Trial): Prospective Open-Label Noninferiority Clinical Trial.

    abstract:BACKGROUND:Digital tools provide a unique opportunity to increase access to eye care. We developed a Web-based test that measures visual acuity and both spherical and cylindrical refractive errors. This test is Conformité Européenne marked and available on the Easee website. The purpose of this study was to compare the...

    journal_title:Journal of medical Internet research

    pub_type: 杂志文章

    doi:10.2196/14808

    authors: Wisse RPL,Muijzer MB,Cassano F,Godefrooij DA,Prevoo YFDM,Soeters N

    更新日期:2019-11-08 00:00:00