First general outbreak of Verocytotoxin-producing Escherichia coli O157 in Denmark.

Abstract:

:This report describes the first general outbreak of verocytotoxin-producing E. coli (VTEC) in Denmark. Twenty five patients, 18 children and seven adults, with culture-confirmed VTEC O157:H- infection and indistinguishable pulsed-field gel electrophoresis DNA profiles, were identified during a six month period from September 2003 to March 2004. The outbreak strain possessed the virulence genes: eae, vtx1 and vtx2c. All patients but one presented with diarrhoea; none developed haemolytic uraemic syndrome. The outbreak was restricted to Copenhagen and surrounding areas. A case-control study including 11 cases and 55 matched controls revealed an association between VTEC O157:H- infection and shopping in a specific supermarket chain in Copenhagen and surrounding area, matched odds ratio (OR): 8.7 (95% confidence interval (CI): 1.1-71). After exclusion of three assumed secondary cases, only consumption of a particular kind of organic milk from a small dairy was associated with disease OR: 8.7 (95% CI 1.6-48). Environmental and microbiological investigations at the suspected dairy did not confirm the presence of the outbreak strain, but the outbreak stopped once the dairy was closed and thoroughly cleaned.

journal_name

Euro Surveill

authors

Jensen C,Ethelberg S,Gervelmeyer A,Nielsen EM,Olsen KE,Mølbak K,The Outbreak Investigation Team

doi

10.2807/esm.11.02.00597-en

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

1-2

issue

2

eissn

1025-496X

issn

1560-7917

journal_volume

11

pub_type

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