Abstract:
BACKGROUND:Overweight and obesity is a major public health concern that includes associations with the development of cardiovascular disease (CVD) risk factors during childhood and adolescence as well as premature mortality in adults. Despite the high prevalence of childhood and adolescent obesity as well as adult CVD, individual studies as well as previous systematic reviews examining the relationship between childhood obesity and adult CVD have yielded conflicting results. The purpose of this study was to use the aggregate data meta-analytic approach to address this gap. METHODS:Studies were included if they met the following criteria: (1) longitudinal and cohort studies (including case-cohort), (2) childhood exposure and adult outcomes collected on the same individual over time, (3) childhood obesity, as defined by the original study authors, (4) English-language articles, (5) studies published up to June, 2015, (6) one or more of the following CVD risk factors [systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol (TC), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), non-high-density lipoprotein cholesterol (non-HDL), and triglycerides (TG)], (7) outcome(s) not self-reported, and (8) exposure measurements (child's adiposity) assessed by health professionals, trained investigators, or self-reported. Studies were retrieved by searching three electronic databases as well as citation tracking. Fisher's r to z score was calculated for each study for each outcome. Pooled effect sizes were calculated using random-effects models while risk of bias was assessed using the STROBE instrument. In order to try and identify sources of heterogeneity, random-effects meta-regression was also performed. RESULTS:Of the 4840 citations reviewed, a total of 23 studies were included in the systematic review and 21 in the meta-analysis. The findings suggested that childhood obesity is significantly and positively associated with adult SBP (Zr = 0.11; 95% CI: 0.07, 0.14), DBP (Zr = 0.11; 95% CI: 0.07, 0.14), and TG (Zr =0.08; 95% CI: 0.03, 0.13), and significantly and inversely associated with adult HDL (Zr = -0.06; 95% CI: -0.10, -0.02). For those studies that adjusted for adult body mass index (BMI), associations were reversed, suggesting that adult BMI may be a potential mediator. Nine studies had more than 33% of items that placed them at an increased risk for bias. CONCLUSIONS:The results of this study suggest that childhood obesity may be a risk factor for selected adult CVD risk factors. However, a need exists for additional, higher-quality studies that include, but are not limited to, both unadjusted and adjusted measures such as BMI before any definitive conclusions can be reached. SYSTEMATIC REVIEW AND META-ANALYSIS:PROSPERO 2015: CRD42015019763 .
journal_name
BMC Public Healthjournal_title
BMC public healthauthors
Umer A,Kelley GA,Cottrell LE,Giacobbi P Jr,Innes KE,Lilly CLdoi
10.1186/s12889-017-4691-zsubject
Has Abstractpub_date
2017-08-29 00:00:00pages
683issue
1issn
1471-2458pii
10.1186/s12889-017-4691-zjournal_volume
17pub_type
杂志文章,meta分析,评审abstract:BACKGROUND:There is strong evidence for the beneficial effects of physical activity in diabetes. There has been little research demonstrating a dose-response relationship between physical activity and self-rated health in diabetics. The aim of this study was to explore the dose-response association between leisure time...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-10-277
更新日期:2010-05-26 00:00:00
abstract:BACKGROUND:Globally, two billion workers are employed informally but there is limited research on the relationship between informal work and health. Existing studies have focused on informality as an employment condition, with little emphasis on the diversity of physical and social contexts in which informal work takes...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-020-08624-6
更新日期:2020-04-19 00:00:00
abstract:BACKGROUND:South Africa's maternal mortality ratio remains high although it has substantially declined in the past few years. Numerous studies undertaken in South Africa on maternal mortality have not paid much attention to how the causes are distributed in different socio-demographic groups. This study assesses and an...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-020-8179-x
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Little is known about how sitting time, alone or in combination with markers of physical activity (PA), influences mental well-being and work productivity. Given the need to develop workplace PA interventions that target employees' health related efficiency outcomes; this study examined the associations betw...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-015-1447-5
更新日期:2015-01-31 00:00:00
abstract:BACKGROUND:Few studies in China have examined personal ultraviolet radiation (UVR) exposure using polysulfone dosimetry. METHODS:In this study, 93 mother and adolescent child pairs (N = 186) from two locations in China, one rural (higher latitude) and one urban (lower latitude), completed 3 days of personal UVR dosime...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-019-6610-y
更新日期:2019-03-08 00:00:00
abstract:BACKGROUND:In July 2011, the Malawi national HIV program implemented the integrated antiretroviral therapy (ART) and prevention of mother-to-child transmission (PMTCT) guidelines. Among the principle goals of the guidelines were increasing ART uptake among TB/HIV co-infected patients and treating TB/HIV patients with a...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-14-183
更新日期:2014-02-20 00:00:00
abstract:BACKGROUND:Although physical activity (PA) integrated in schools' classrooms have shown a positive effect on children's behaviors, its effectiveness on cognitive functions, PA levels and other health variables remains unclear. This article outlines the rationale and methods of two classroom-based PA interventions (MOVI...
journal_title:BMC public health
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12889-019-6742-0
更新日期:2019-04-18 00:00:00
abstract:BACKGROUND:Health systems have experienced unprecedented stress in recent years, and as yet no consensus has emerged as to how to deal with the multiple burden of disease in the context of HIV and AIDS and other competing health priorities. Priority setting is essential, yet this is a complex, multifaceted process. Dra...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-12-1071
更新日期:2012-12-11 00:00:00
abstract:BACKGROUND:Immunization is an effective public health intervention to reduce morbidity and mortality among children and it will become more effective if the child can receive the full course of recommended immunization doses. The objective of this study was to determine the prevalence of childhood immunization defaulte...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-019-7561-z
更新日期:2019-09-18 00:00:00
abstract:BACKGROUND:The technical efficiency (TE) of care among the elderly in long-term care facilities (LTCF) have become increasingly crucial policy concerns faced by developing countries and Asia, especially China. The purpose of this study was to evaluate the TE and the quality of care and identify its influencing factors ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-019-7571-x
更新日期:2019-09-05 00:00:00
abstract:BACKGROUND:This study tests associations between psychosocial stress at work measured by the effort-reward imbalance model in a dynamic perspective, and multiple indicators of poor mental health, in a prospective design. METHODS:1986 male and female employees from four Belgian enterprises were followed-up over one yea...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-5-67
更新日期:2005-06-15 00:00:00
abstract:BACKGROUND:Social relations influence mental health through different pathways. To capture the complexity of social relations, it is beneficial to consider both the structural (e.g., reachability of social network and social integration) and functional (e.g., instrumental and emotional support) aspects of the concept. ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-017-4871-x
更新日期:2017-11-03 00:00:00
abstract:BACKGROUND:Fear of falling and avoidance of activity are common in old age and are suggested to be (public) health problems of equal importance to falls. Earlier studies of correlates of fear of falling and avoidance of activity did hardly differentiate between severe and mild levels of fear of falling and avoidance of...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-9-170
更新日期:2009-06-02 00:00:00
abstract:BACKGROUND:Parental knowledge of child development has been associated with more effective parenting strategies and better child outcomes. However, little is known about what adults who interact with children under the age of 14 years know about child development. METHODS:Between September 2007 and March 2008, compute...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-10-183
更新日期:2010-04-08 00:00:00
abstract:BACKGROUND:Previous studies have focused on the relationship between employment pathways and health-related outcomes based on cross-sectional or longitudinal approaches. However, little is known about the cumulative effects of employment status mobility on sickness absence (SA) over time. The aim of the present study w...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-020-09396-9
更新日期:2020-08-27 00:00:00
abstract:BACKGROUND:Young breast cancer patients have a lower rate of survival than old breast cancer patients due to being diagnosed at advanced stages. Breast self-examination makes women more "breast aware", which in turn may lead to an earlier diagnosis of breast cancer. The purpose of this study was to investigate knowledg...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-8-359
更新日期:2008-10-17 00:00:00
abstract:BACKGROUND:Since prevalence estimates of recommended physical activity (PA) considerably vary between different surveys, prevalence might be crucially affected by the choice of measuring instrument. The aim of the present study is to compare the results of four PA questionnaires regarding the current moderate- and vigo...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-020-10113-9
更新日期:2021-01-07 00:00:00
abstract:BACKGROUND:Mixed evidence exists with respect to the association between household food insecurity (HFIS) and obesity in low-to-middle income countries (LMICs), particularly among women. This study aimed to measure socioeconomic correlates of HFIS and explores its association with dietary intake and odds of obesity amo...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-017-4317-5
更新日期:2017-06-12 00:00:00
abstract:BACKGROUND:The debate on socioeconomic inequalities in health dominates the research and policy agenda of many countries. The prevalence of non-communicable diseases (NCDs) is on the rise in recent years in Botswana. As a prevention and policy effort, the study provided an empirical evidence on socioeconomic inequaliti...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-019-7405-x
更新日期:2019-08-07 00:00:00
abstract:BACKGROUND:Respiratory infections are the leading cause of childhood deaths in Bangladesh. Promoting respiratory hygiene may reduce infection transmission. This formative research explored community perceptions about respiratory infections. METHODS:We conducted 34 in-depth interviews and 16 focus group discussions wit...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-11-901
更新日期:2011-12-04 00:00:00
abstract:BACKGROUND:Mental health problems have become more common among young people over the last twenty years, especially in certain countries. The reasons for this have remained unclear. The hypothesis tested in this study is that national trends in young people's mental health are associated with national trends in young p...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-9-325
更新日期:2009-09-08 00:00:00
abstract:BACKGROUND:The introduction of antiretroviral therapy (ART) has sharply decreased morbidity and mortality rates among HIV infected patients. Due to this, more and more people with HIV live longer and healthier lives. Yet if they practice sex without condom, those with high viral load have the potential to infect their ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-12-308
更新日期:2012-04-26 00:00:00
abstract:BACKGROUND:The aims of this study were 1) to clarify the prevalence of sleep problems (insomnia, insufficient sleep, and delayed sleep-wake phase) among Japanese university students; 2) to examine sociodemographic characteristics, lifestyle, and sleep-related symptoms in each sleep problem; and 3) to evaluate the assoc...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-020-08483-1
更新日期:2020-03-20 00:00:00
abstract:BACKGROUND:In May 2010, Switzerland introduced a heterogeneous smoking ban in the hospitality sector. While the law leaves room for exceptions in some cantons, it is comprehensive in others. This longitudinal study uses different measurement methods to examine airborne nicotine levels in hospitality venues and the leve...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-13-536
更新日期:2013-06-04 00:00:00
abstract:BACKGROUND:Parent-child communication about sexual issues can reduce risky sexual behaviour amongst adolescents. Risky sexual behaviour is of concern in sub-Saharan Africa where the prevalence of early pregnancy, unsafe abortion and HIV are high. Parent-child communication about sexual issues presents a feasible approa...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-020-09218-y
更新日期:2020-07-16 00:00:00
abstract:BACKGROUND:In France, 2-15% of the population is affected annually by influenza, which causes significant socioeconomic disruption. Nevertheless, despite its importance for policy makers, few published studies have evaluated the impact of influenza B. Therefore, we assessed the costs associated with influenza B during ...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/1471-2458-14-56
更新日期:2014-01-20 00:00:00
abstract:BACKGROUND:Age disparities in sexual relationships have been proposed as a key risk factor for HIV transmission in Sub-Saharan Africa, but evidence remains inconclusive. The SIHR study, a cluster randomised trial of a cash transfer programme in Malawi, found that young women in the intervention groups were less likely ...
journal_title:BMC public health
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12889-018-5327-7
更新日期:2018-03-27 00:00:00
abstract:BACKGROUND:Chlamydia trachomatis (CT) is a common sexually transmitted infection (STI) with significant morbidity. The study aimed to explore the willingness to undergo routine CT screening and its associated factors among hospital-based patients in Shenzhen. METHODS:We used data from the Shenzhen Gonorrhea and Chlamy...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-020-09828-6
更新日期:2020-11-16 00:00:00
abstract:BACKGROUND:Research has shown that sexual minorities (SMs) (e.g. lesbian, gay, and bisexual individuals), compared to their heterosexual counterparts, may engage in riskier health behaviors, are at higher risk of some adverse health outcomes, and are more likely to experience reduced health care access and utilization....
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-017-4937-9
更新日期:2017-12-19 00:00:00
abstract:BACKGROUND:Societal expenditures on work-disability benefits is high in most Western countries. As a precursor of long-term work restrictions, long-term sickness absence (LTSA) is under continuous attention of policy makers. Different healthcare professionals can play a role in identification of persons at risk of LTSA...
journal_title:BMC public health
pub_type: 杂志文章
doi:10.1186/s12889-020-08843-x
更新日期:2020-05-15 00:00:00