当前位置： SCI文献检索 > BMC Complementary and Alternative Medicine期刊下所有文献 > Neuroprotective effect of Aronia melanocarpa extract against glutamate-induced oxidative stress in HT22 cells.

Neuroprotective effect of Aronia melanocarpa extract against glutamate-induced oxidative stress in HT22 cells.

Abstract：

BACKGROUND:Glutamate (an endogenous excitatory neurotransmitter) at high concentrations contributes to the development of neurodegenerative diseases. Aronia melanocarpa (A. melanocarpa) berries contain anthocyanins and have high antioxidant activities. In this study, we evaluated whether A. melanocarpa berries could protect neuronal cells against glutamate-induced oxidative stress. METHOD:A. melanocarpa berries exerted a protective effect against cytotoxicity in HT22 mouse hippocampal cells by MTT assay. We evaluated oxidative stress parameters including ROS level, intracellular Ca2+ level, glutathione level and antioxidant enzyme activity in HT22 cells to elucidate the mechanism of its neuroprotective effect. RESULTS:A. melanocarpa berries decreased glutamate-induced death of HT22 cells. In addition, A. melanocarpa berries reduced ROS and intracellular Ca2+ levels. Glutathione level, antioxidant enzymes, glutathione reductase and glutathione peroxide activities and mitochondrial membrane potential were also increased in HT22 cells. CONCLUSION:These results suggested that A. melanocarpa berries protected HT22 cells by exerting an antioxidant effect.

journal_name

BMC Complement Altern Med

journal_title

BMC complementary and alternative medicine

authors

Lee HY,Weon JB,Ryu G,Yang WS,Kim NY,Kim MK,Ma CJ

doi

10.1186/s12906-017-1716-1

subject

Has Abstract

pub_date

2017-04-11 00:00:00

pages

207

issue

1

issn

1472-6882

pii

10.1186/s12906-017-1716-1

journal_volume

17

pub_type

杂志文章

相关文献

BMC Complementary and Alternative Medicine文献大全
  • Assessment of phytochemicals, antimicrobial and cytotoxic activities of extract and fractions from Fagonia olivieri (Zygophyllaceae).

    abstract：BACKGROUND:In Pakistan Fagonia olivieri (Zygophyllaceae) is commonly used in the indigenous system of medicine for treatment of conditions like diabetes, cancer, fever, asthma, toothache, stomach troubles and kidney disorders. This study evaluated the crude methanol extract of F. olivieri (FOM) and its derived fraction...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-13-167

    authors： Rashid U,Khan MR,Jan S,Bokhari J,Shah NA

    更新日期：2013-07-10 00:00:00

  • Perceptions, use and attitudes of pharmacy customers on complementary medicines and pharmacy practice.

    abstract：BACKGROUND:Complementary medicines (CMs) are popular amongst Australians and community pharmacy is a major supplier of these products. This study explores pharmacy customer use, attitudes and perceptions of complementary medicines, and their expectations of pharmacists as they relate to these products. METHODS:Pharmac...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-10-38

    authors： Braun LA,Tiralongo E,Wilkinson JM,Spitzer O,Bailey M,Poole S,Dooley M

    更新日期：2010-07-20 00:00:00

  • Potential effectiveness of Chinese herbal medicine Yu ping feng san for adult allergic rhinitis: a systematic review and meta-analysis of randomized controlled trials.

    abstract：BACKGROUND:Chinese herbal medicine formula Yu ping feng san (YPFS) is commonly used for allergic rhinitis (AR). Previous review had summarized the effectiveness and safety of YPFS, however without any subgroup analysis performed to provide detailed evidence for guiding clinical practice. YPFS was recommended for the ma...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章,meta分析,评审

    doi：10.1186/s12906-017-1988-5

    authors： Luo Q,Zhang CS,Yang L,Zhang AL,Guo X,Xue CC,Lu C

    更新日期：2017-11-06 00:00:00

  • Synergistic gastroprotective activity of methanolic extract of a mixture of Melastoma malabathricum and Muntingia calabura leaves in rats.

    abstract：BACKGROUND:Melastoma malabathricum L. (family Melastomaceae; MM) and Muntingia calabura L. (family Elaeocarpaceae; MC) have been separately reported to possess gastroprotective activity. In an attempt to develop a pharmaceutical product with antiulcer potential, the synergistic gastroprotective activity of methanolic e...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-017-1992-9

    authors： Halim SZ,Zakaria ZA,Omar MH,Mohtarrudin N,Wahab IRA,Abdullah MNH

    更新日期：2017-11-09 00:00:00

  • The effects of the court-type Thai traditional massage on anatomical relations, blood flow, and skin temperature of the neck, shoulder, and arm.

    abstract：BACKGROUND:Court-type Thai traditional massage (CTTM) has specific major signal points (MaSP) for treating musculoskeletal conditions. The objectives of this study are to investigate the anatomical surfaces and structures of MaSPs, and to examine blood flow (BF) and skin temperature (ST) changes after applying pressure...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-016-1282-y

    authors： Plakornkul V,Vannabhum M,Viravud Y,Roongruangchai J,Mutirangura P,Akarasereenont P,Laohapand T

    更新日期：2016-09-15 00:00:00

  • Appraisal of phytochemical and in vitro biological attributes of an unexplored folklore: Rhus Punjabensis Stewart.

    abstract：BACKGROUND:The role of plants for discovery of therapeutic potential accentuates the need to know their biological attributes. The present study aims to comprehend the biological attributes of Rhus punjabensis, an unexplored traditional medicinal plant. METHODS:Leaf and stem extracts of R. punjabensis prepared in 11 d...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-017-1659-6

    authors： Tabassum S,Ahmed M,Mirza B,Naeem M,Zia M,Shanwari ZK,Khan GM

    更新日期：2017-03-09 00:00:00

  • Citral induced apoptosis in MDA-MB-231 spheroid cells.

    abstract：BACKGROUND:Breast cancer remains a leading cause of death in women worldwide. Although breast cancer therapies have greatly advanced in recent years, many patients still develop tumour recurrence and metastasis, and eventually succumb to the disease due to chemoresistance. Citral has been reported to show cytotoxic eff...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-018-2115-y

    authors： Nigjeh SE,Yeap SK,Nordin N,Kamalideghan B,Ky H,Rosli R

    更新日期：2018-02-13 00:00:00

  • Rhodiola crenulata extract counteracts the effect of hypobaric hypoxia in rat heart via redirection of the nitric oxide and arginase 1 pathway.

    abstract：BACKGROUND:Rhodiola crenulata is traditionally used as a folk medicine in Tibet for preventing high-altitude illnesses, including sudden cardiac death (SCD). The cardio-protective effects of Rhodiola crenulata root extract (RCE) against hypoxia in vivo have been recently confirmed. However, the way in which RCE produce...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-016-1524-z

    authors： Hsu SW,Chang TC,Wu YK,Lin KT,Shi LS,Lee SY

    更新日期：2017-01-07 00:00:00

  • KOTMIN13, a Korean herbal medicine alleviates allergic inflammation in vivo and in vitro.

    abstract：BACKGROUND:The ethanol extract of KOTMIN13, composed of Inula japonica Flowers, Trichosanthes kirilowii Semen, Peucedanum praeruptorum Radix, and Allium macrostemon Bulbs, was investigated for its anti-asthmatic and anti-allergic activities. METHODS:The anti-asthmatic effects of KOTMIN13 were evaluated on ovalbumin (O...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-016-1155-4

    authors： Lee E,Kim SG,Park NY,Park HH,Jeong KT,Choi J,Lee IH,Lee H,Kim KJ,Lee E

    更新日期：2016-06-06 00:00:00

  • Anti-atherosclerotic effect of traditional fermented cheese whey in atherosclerotic rabbits and identification of probiotics.

    abstract：BACKGROUND:Traditional fermented cheese whey (TFCW), containing probiotics, has been used both as a dairy food with ethnic flavor and a medicine for cardiovascular disease, especially regulating blood lipid among Kazakh. We therefore investigated anti-atherosclerotic effects of TFCW in atherosclerotic rabbits and ident...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-016-1285-8

    authors： Nabi XH,Ma CY,Manaer T,Heizati M,Wulazibieke B,Aierken L

    更新日期：2016-08-24 00:00:00

  • Urox containing concentrated extracts of Crataeva nurvala stem bark, Equisetum arvense stem and Lindera aggregata root, in the treatment of symptoms of overactive bladder and urinary incontinence: a phase 2, randomised, double-blind placebo controlled tri

    abstract：BACKGROUND:Storage lower urinary tract symptoms (LUTS) including overactive bladder (OAB) and urinary incontinence (UI) affect millions of people worldwide, significantly impacting quality of life. Plant based medicines have been documented both empirically and in emerging scientific research to have varying benefits i...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章,随机对照试验

    doi：10.1186/s12906-018-2101-4

    authors： Schoendorfer N,Sharp N,Seipel T,Schauss AG,Ahuja KDK

    更新日期：2018-01-31 00:00:00

  • Biological properties of Elaeagnus rhamnoides (L.) A. Nelson twig and leaf extracts.

    abstract：BACKGROUND:Sea buckthorn (Elaeagnus rhamnoides (L.) A. Nelson, SBT) is a valuable plant because of its medical and therapeutic potential. Different bioactive compounds in SBT berries are of special interest to various researchers. However, not only sea buckthorn berries, but also leaves of this plant (both fresh and dr...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-019-2564-y

    authors： Skalski B,Kontek B,Lis B,Olas B,Grabarczyk Ł,Stochmal A,Żuchowski J

    更新日期：2019-06-25 00:00:00

  • Thai plants with high antioxidant levels, free radical scavenging activity, anti-tyrosinase and anti-collagenase activity.

    abstract：BACKGROUND:Ultraviolet radiation from sunlight induces overproduction of reactive oxygen species (ROS) resulting in skin photoaging and hyperpigmentation disorders. Novel whitening and anti-wrinkle compounds from natural products have recently become of increasing interest. The purpose of this study was to find product...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-017-1994-7

    authors： Chatatikun M,Chiabchalard A

    更新日期：2017-11-09 00:00:00

  • The combination of Artemisia princeps Pamp, Leonurus japonicas Houtt, and Gardenia jasminoides Ellis fruit attenuates the exacerbation of energy, lipid, and glucose by increasing hepatic PGC-1α expression in estrogen-deficient rats.

    abstract：BACKGROUND:Artemisia princeps Pamp (APP), Leonurus japonicas Houtt (LJH), and Gardenia jasminoides Ellis fruit (GJE) have been traditionally used in East Asia to treat women's diseases related to reproductive system. They may attenuate the deterioration of energy, lipid, glucose and bone metabolism by estrogen deficien...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-016-1109-x

    authors： Yang HJ,Kim MJ,Kwon DY,Moon BR,Kim AR,Kang S,Park S

    更新日期：2016-05-23 00:00:00

  • Perceptions of traditional Chinese medicine for chronic disease care and prevention: a cross-sectional study of Chinese hospital-based health care professionals.

    abstract：BACKGROUND:In China, demands for disease prevention and health care and the prevalence of chronic non-communicable diseases have increased. TCM and general hospitals are increasingly utilizing TCM strategies for chronic non-communicable disease care and prevention. This study aimed to investigate health care profession...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-018-2273-y

    authors： Fan X,Meng F,Wang D,Guo Q,Ji Z,Yang L,Ogihara A

    更新日期：2018-07-06 00:00:00

  • Isolation and biological activity of triglycerides of the fermented mushroom of Coprinus Comatus.

    abstract：BACKGROUND:Although many physiological functions of Coprinus comatus have been reported, there has been no report on the antinociceptive activity of Coprinus comatus. Therefore, the objective of the present study is to demonstrate the production, isolation, and biological properties of triglycerides (TFC) of the fermen...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-12-52

    authors： Ren J,Shi JL,Han CC,Liu ZQ,Guo JY

    更新日期：2012-04-24 00:00:00

  • In vitro biological assessment of Berberis vulgaris and its active constituent, berberine: antioxidants, anti-acetylcholinesterase, anti-diabetic and anticancer effects.

    abstract：BACKGROUND:Berberis vulgaris is a well known plant with traditional herbal medical history. The aims of this study was to bioscreen and compare the in vitro biological activity (antioxidant, cholinergic, antidaibetic and the anticancer) of barberry crude extract and berberine active compound. METHODS:The effect of B. ...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-13-218

    authors： Abd El-Wahab AE,Ghareeb DA,Sarhan EE,Abu-Serie MM,El Demellawy MA

    更新日期：2013-09-05 00:00:00

  • Building resilience: a preliminary exploration of women's perceptions of the use of acupuncture as an adjunct to In Vitro Fertilisation.

    abstract：BACKGROUND:In Vitro Fertilisation (IVF) is now an accepted and effective treatment for infertility, however IVF is acknowledged as contributing to, rather than lessening, the overall psychosocial effects of infertility. Psychological and counselling interventions have previously been widely recommended in parallel with...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-9-50

    authors： de Lacey S,Smith CA,Paterson C

    更新日期：2009-12-12 00:00:00

  • Differences in the quality of interpersonal care in complementary and conventional medicine.

    abstract：BACKGROUND:The study was part of a nationwide evaluation of complementary and alternative medicine (CAM) in Swiss primary care. The aim of the study was to compare patient-physician relationships and the respective patient-reported relief of symptoms between CAM and conventional primary care (COM). METHODS:A comparati...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-10-63

    authors： Busato A,Künzi B

    更新日期：2010-11-04 00:00:00

  • Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells.

    abstract：BACKGROUND:Flavonoid-rich extracts from the mature roots of Scutellaria baicalensis have been shown to exhibit antiproliferative effects on various cancer cell lines. We assessed the ability of an ethanolic extract of S. baicalensis root to inhibit the proliferation of malignant glioma cells. METHODS:Cell lines derive...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-6-27

    authors： Scheck AC,Perry K,Hank NC,Clark WD

    更新日期：2006-08-16 00:00:00

  • Impact of Tai Chi exercise on multiple fracture-related risk factors in post-menopausal osteopenic women: a pilot pragmatic, randomized trial.

    abstract：BACKGROUND:Tai Chi (TC) is a mind-body exercise that shows potential as an effective and safe intervention for preventing fall-related fractures in the elderly. Few randomized trials have simultaneously evaluated TC's potential to reduce bone loss and improve fall-predictive balance parameters in osteopenic women. MET...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章,随机对照试验

    doi：10.1186/1472-6882-12-7

    authors： Wayne PM,Kiel DP,Buring JE,Connors EM,Bonato P,Yeh GY,Cohen CJ,Mancinelli C,Davis RB

    更新日期：2012-01-30 00:00:00

  • Cytotoxic, antioxidative, genotoxic and antigenotoxic effects of Horchata, beverage of South Ecuador.

    abstract：BACKGROUND:"Horchata" is an herbal mixture infusion consumed in Southern Ecuador; 66% of its plants are anti-inflammatory medicinal plant, and 51% are analgesics. Anti-inflammatory substances can prevent carcinogenesis mediated by cytotoxic effects and can prevent DNA damage. The aim of this study was to evaluate the c...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-017-2048-x

    authors： Bailon-Moscoso N,Tinitana F,Martínez-Espinosa R,Jaramillo-Velez A,Palacio-Arpi A,Aguilar-Hernandez J,Romero-Benavides JC

    更新日期：2017-12-19 00:00:00

  • How might acupuncture work? A systematic review of physiologic rationales from clinical trials.

    abstract：BACKGROUND:Scientific interest in acupuncture has led numerous investigators to conduct clinical trials to test the efficacy of acupuncture for various conditions, but the mechanisms underlying acupuncture are poorly understood. METHODS:The author conducted a PubMed search to obtain a fair sample of acupuncture clinic...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章,评审

    doi：10.1186/1472-6882-6-25

    authors： Moffet HH

    更新日期：2006-07-07 00:00:00

  • Preliminary study of the antioxidant properties of flowers and roots of Pyrostegia venusta (Ker Gawl) Miers.

    abstract：BACKGROUND:Free radical stress leads to tissue injury and can eventually to arthritis, atherosclerosis, diabetes mellitus, neurodegenerative diseases and carcinogenesis. Several studies are ongoing worldwide to find natural antioxidants of plant origin. We assessed the in-vitro antioxidant activities and screened the p...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-11-69

    authors： Roy P,Amdekar S,Kumar A,Singh V

    更新日期：2011-08-23 00:00:00

  • Gastroprotective effect of desmosdumotin C isolated from Mitrella kentii against ethanol-induced gastric mucosal hemorrhage in rats: possible involvement of glutathione, heat-shock protein-70, sulfhydryl compounds, nitric oxide, and anti-Helicobacter pylo

    abstract：BACKGROUND:Mitrella kentii (M. kentii) (Bl.) Miq, is a tree-climbing liana that belongs to the family Annonaceae. The plant is rich with isoquinoline alkaloids, terpenylated dihydrochalcones and benzoic acids and has been reported to possess anti-inflammatory activity. The purpose of this study is to assess the gastrop...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-13-183

    authors： Sidahmed HM,Azizan AH,Mohan S,Abdulla MA,Abdelwahab SI,Taha MM,Hadi AH,Ketuly KA,Hashim NM,Loke MF,Vadivelu J

    更新日期：2013-07-19 00:00:00

  • The effect of freeze-dried Carica papaya leaf juice treatment on NS1 and viremia levels in dengue fever mice model.

    abstract：BACKGROUND:Carica papaya leaf juice (CPLJ) was well known for its thrombocytosis activity in rodents and dengue patients. However, the effect of CPLJ treatment on other parameters that could contribute to dengue pathogenesis such as nonstructural protein 1 (NS1) production and viremia level have never been highlighted ...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-018-2390-7

    authors： Mohd Abd Razak MR,Mohmad Misnan N,Md Jelas NH,Norahmad NA,Muhammad A,Ho TCD,Jusoh B,Sastu UR,Zainol M,Wasiman MI,Muhammad H,Thayan R,Syed Mohamed AF

    更新日期：2018-12-05 00:00:00

  • What do clinicians want? Interest in integrative health services at a North Carolina academic medical center.

    abstract：BACKGROUND:Use of complementary medicine is common, consumer driven and usually outpatient focused. We wished to determine interest among the medical staff at a North Carolina academic medical center in integrating diverse therapies and services into comprehensive care. METHODS:We conducted a cross sectional on-line s...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-7-5

    authors： Kemper KJ,Dirkse D,Eadie D,Pennington M

    更新日期：2007-02-09 00:00:00

  • New Canadian natural health product regulations: a qualitative study of how CAM practitioners perceive they will be impacted.

    abstract：BACKGROUND:New Canadian policy to regulate natural health products (NHPs), such as herbs and vitamins were implemented on January 1st, 2004. We explored complementary and alternative medicine (CAM) practitioners' perceptions of how the new regulations may affect their practices and relationships with patients/consumers...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/1472-6882-6-18

    authors： Moss K,Boon H,Ballantyne P,Kachan N

    更新日期：2006-05-10 00:00:00

  • Effect of DanQi Pill on PPARα, lipid disorders and arachidonic acid pathway in rat model of coronary heart disease.

    abstract：BACKGROUND:Danqi pill (DQP) is one of the most widely prescribed formulas and has been shown to have remarkable protective effect on coronary heart disease (CHD). However, its regulatory effects on lipid metabolism disorders haven't been comprehensively studied so far. We aimed to explore the effects of DQP on Peroxiso...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-016-1083-3

    authors： Chang H,Wang Q,Shi T,Huo K,Li C,Zhang Q,Wang G,Wang Y,Tang B,Wang W,Wang Y

    更新日期：2016-03-22 00:00:00

  • ViscumTT induces apoptosis and alters IAP expression in osteosarcoma in vitro and has synergistic action when combined with different chemotherapeutic drugs.

    abstract：BACKGROUND:Osteosarcoma is the most common bone tumor and is associated with a poor prognosis. Conventional therapies, surgery and chemotherapy, are still the standard but soon reach their limits. New therapeutic approaches are therefore needed. Conventional aqueous mistletoe extracts from the European mistletoe (Viscu...

    journal_title：BMC complementary and alternative medicine

    pub_type： 杂志文章

    doi：10.1186/s12906-016-1545-7

    authors： Kleinsimon S,Kauczor G,Jaeger S,Eggert A,Seifert G,Delebinski C

    更新日期：2017-01-07 00:00:00