Anticoagulation Management and Monitoring during Pediatric Extracorporeal Life Support: A Review of Current Issues.

Abstract:

:Anticoagulation is an imperfect science and is even more complicated in neonates and young children. The addition of the extracorporeal life support (ECLS) foreign circuit adds an additional layer of complexity. Anticoagulation goals during ECLS are to maintain a clot-free circuit and a hemostatically balanced patient. Unfractionated heparin (UFH) is the default gold standard anticoagulant as no large studies have been performed on any other anticoagulants. This review will focus on the advantages and disadvantages of the various methods to monitor UFH anticoagulation, discuss alternative anticoagulants, and examine bleeding and thrombotic complications during ECLS.

journal_name

Front Pediatr

journal_title

Frontiers in pediatrics

authors

Ryerson LM,Lequier LL

doi

10.3389/fped.2016.00067

subject

Has Abstract

pub_date

2016-06-22 00:00:00

pages

67

issn

2296-2360

journal_volume

4

pub_type

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