Spontaneous remission of eosinophilic granuloma of the maxilla after incisional biopsy: a case report.

Abstract:

BACKGROUND:Langerhans cell histiocytosis (LCH), previously known as Histiocytosis X, is an infrequent disease that congregates a wide spectrum of clinical presentations with variable systemic involvement. Unification of these diseases under only one category is based on the almost identical histopathologic features of the lesions, but the etiology and proper approach for each presentation remains controversial. The localized alternative of Langerhans cell histiocytosis (LLCH), known as Eosinophilic Granuloma (EG) of bone, is the predominant clinical presentation of LCH. The maxilla is involved in 1 % of the head and neck region cases, representing an uncommon condition in this area. CASE PRESENTATION:In this clinical case report, it is described a case of a 16-year-old male patient with an asymptomatic osteolytic lesion at first upper left molar apical level, a finding detected on control radiographic images was reported as "Monostotic Eosinophilic granuloma of the maxillary bone", which was later confirmed through an incisional biopsy. A surgical excision was initially planned, but finally it was not performed due to a spontaneous healing of the lesion after the incisional biopsy. CONCLUSIONS:The presented case supports a conservative approach in the management of solitary EG of maxillary and mandibular bone lesions and even supports an expectant attitude in the course of treatment given the possibility of a spontaneous regression after the biopsy, especially in small lesions.

journal_name

Head Face Med

journal_title

Head & face medicine

authors

Vargas A,Ramírez H,Ramírez P,Foncea C,Venegas B,Astorga P

doi

10.1186/s13005-016-0118-9

subject

Has Abstract

pub_date

2016-06-02 00:00:00

pages

21

issue

1

issn

1746-160X

pii

10.1186/s13005-016-0118-9

journal_volume

12

pub_type

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