Abstract：
BACKGROUND:Apoptosis, or programmed cell death is a form of physiological cell death. It is increased or decreased in the presence of infection, inflammation or tissue remodelling. Previous studies suggest that apoptosis is involved in the pathogenesis of inflammatory periodontal disease. The aim of the present study was to investigate the clinical features and known indicators of apoptosis (p53, Bcl-2, Caspase-3) in patients with generalized aggressive periodontitis (GAP) METHODS: Eight patients with GAP, who had sites with probing depths (PD) > 5 mm, and 10 periodontally-healthy persons were included in the study. Clinical examinations and PD were performed, and the plaque index and gingival index were recorded. Gingival tissues biopsies were obtained from active site of each patient and from healthy individuals. The expression of caspase-3, Bcl-2, and p53 was evaluated by immunohistochemistry RESULTS:There were no significant differences between GAP and control group with respect to levels of caspase-3 and p53 expression (P > 0.05). Contrary, the frequency of grade 3 expression of Bcl-2 was higher in GAP group than the control group. CONCLUSION:The higher frequency of Bcl-2 expression in GAP group indicates and delayed apoptosis can lead to increasing resident inflammatory cells in periodontal tissues and resulting in progressive periodontal destruction.
journal_name
Head Face Medjournal_title
Head & face medicineauthors
Bulut S,Uslu H,Ozdemir BH,Bulut OEdoi
10.1186/1746-160X-2-17subject
Has Abstractpub_date
2006-06-20 00:00:00pages
17issn
1746-160Xpii
1746-160X-2-17journal_volume
2pub_type
杂志文章abstract：INTRODUCTION:Various surgical procedures are available to correct paralytic ectropion, which are applied in irreversible facial paresis. Problems occur when facial paresis has an unclear prognosis, since surgery of the lower eyelid is usually irreversible. We propose a simple method to correct temporary ectropion in fa...
journal_title：Head & face medicine
pub_type： 临床试验,杂志文章
doi：10.1186/1746-160X-4-12
更新日期：2008-07-21 00:00:00
abstract：BACKGROUND:Functional and aesthetic mandibular reconstruction after ablative tumor surgery continues to be a challenge even after the introduction of microvascular bone transfer. Complex microvascular reconstruction of the resection site requires accurate preoperative planning. In the recent past, bone graft and fixati...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/1746-160X-3-5
更新日期：2007-01-15 00:00:00
abstract：BACKGROUND:The reconstruction of large head and face missing structures in the craniofacial region in children is very challenging for plastic surgeons. Expanded local and expanded axial-pattern flaps are widely used for the reconstruction of large-area scars. Free flaps are used very cautiously in children. 3D printin...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/s13005-020-00219-1
更新日期：2020-03-03 00:00:00
abstract：OBJECTIVES:Simultaneous, radiation-free registration of the teeth and the upper and lower jaw positions in relation to the extraoral soft tissue could improve treatment planning and documentation. The purpose of this study is to describe a workflow to solve this form of registration and surface acquisition with a mobil...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/s13005-019-0212-x
更新日期：2019-11-25 00:00:00
abstract：:Melanotic neuroectodermal tumor of infancy (MNTI) is a rare condition that occurs normally in the anterior maxilla of infants aged <1 year. The use of clinical and imaging tools for MNTI is extremely important to prevent problems with function as well as the aesthetic features in a breastfeeding child. Brazil is a mul...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/1746-160X-9-35
更新日期：2013-11-25 00:00:00
abstract：OBJECTIVE:Patients suspected of having swallowing disorders, could highly benefit from simple diagnostic screening before being referred to specialist evaluations. The article analyzes various instrumental methods of dysphagia assessment, introduces surface electromyography (sEMG) to carry out rapid assessment of such ...
journal_title：Head & face medicine
pub_type： 杂志文章,评审
doi：10.1186/1746-160X-5-9
更新日期：2009-02-20 00:00:00
abstract：BACKGROUND:The purpose of this study was to assess the influence of head and neck pathologies on the detection rate, configuration and diameter of the thoracic duct (TD) and right lymphatic duct (RLD) in computed tomography (CT) of the head and neck. METHODS:One hundred ninety-seven patients were divided into the subg...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/s13005-016-0108-y
更新日期：2016-03-31 00:00:00
abstract：BACKGROUND:CHARGE syndrome (CS) is a rare genetic condition (OMIM #214800). The condition has a variable phenotypic expression. Historically, the diagnosis of CHARGE syndrome was based on the presence of specific clinical criteria. The genetic aetiology of CS has since been elucidated and attributed to pathogenic varia...
journal_title：Head & face medicine
pub_type： 杂志文章,评审
doi：10.1186/s13005-020-00224-4
更新日期：2020-05-08 00:00:00
abstract：OBJECTIVE:To analyze the interradicular trabecular bone density of the lateral maxilla regarding the insertion of temporary anchorage devices (TADs). MATERIAL AND METHODS:The material consisted of tissue blocks of autopsy material from 20 subjects (17 male, 3 female, 16 - 63y). The specimens comprised the dentated alv...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/s13005-015-0058-9
更新日期：2015-02-07 00:00:00
abstract：BACKGROUND:Recently, medical rapid prototyping (MRP) models, fabricated with computer-aided design and computer-aided manufacture (CAD/CAM) techniques, have been applied to reconstructive surgery in the treatment of head and neck cancers. Here, we tested the use of preoperatively manufactured reconstruction plates, whi...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/1746-160X-10-45
更新日期：2014-10-23 00:00:00
abstract：BACKGROUND:The apparent interactions between the mechanisms of action of non-steroidal anti-inflammatory drugs (NSAIDS) and steroids suggest that co-therapy may provide beneficial inflammatory and pain relief in the absence of side effects. The aim of the study was to compare the effect of co-administered dexamethasone...
journal_title：Head & face medicine
pub_type： 杂志文章,随机对照试验
doi：10.1186/1746-160X-1-11
更新日期：2005-11-07 00:00:00
abstract：:There is no doubt that the main reason for an internal grauloma is a traumatic event. The trauma may be physical or chemical as in the case of caries or coronal pulpectomy. In most of the cases it is diagnosed by hazard or, when in case of fracture or mobility, extraction is the only therapy to be performed. If diagno...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/s13005-015-0077-6
更新日期：2015-06-12 00:00:00
abstract：INTRODUCTION:This study determined the amount and severity of EARR (external apical root resorption) after orthodontic treatment with self-ligating (SL) and conventional (Non-SL) brackets. Differences regarding rate of extraction cases, appointments and treatment time were evaluated. MATERIAL AND METHODS:213 patients ...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/1746-160X-10-2
更新日期：2014-01-23 00:00:00
abstract：INTRODUCTION:The aim of the study was to compare the detectability of neck vessels with contrast enhanced magnetic resonance angiography (MRA) in the setting of a whole-body MRA and multislice computed tomography angiography (CTA) for preoperative vascular mapping of head and neck. METHODS:In 20 patients MRA was perfo...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/1746-160X-10-16
更新日期：2014-05-12 00:00:00
abstract：BACKGROUND:A pneumatized superior turbinate is a rare cause of headache. Nasal endoscopy alone, does not provide us with adequate information for this inaccessible area of the superior nasal cavity. A coronal computed tomography (CT) must be obtained to confirm the diagnosis. CASE PRESENTATION:We present a 40-year-old...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/1746-160X-3-3
更新日期：2007-01-09 00:00:00
abstract：INTRODUCTION:The annual examination of first graders' oral health as stipulated by law aimed to reach every child in Rhineland-Palatinate (Germany) in their first year of school. We intended to evaluate the first graders' oral health based on the examination data for 2013/2014. METHODS:Instructed examiners measured th...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/s13005-015-0091-8
更新日期：2015-10-02 00:00:00
abstract：:Ectopic internal carotid artery (ICA) is a very rare variation. The major congenital abnormalities of the ICA can be classified as agenesis, aplasia and hypoplasia, and they can be unilateral or bilateral. Anomalies of the neck artery may be vascular neoplasms or ectopic position. Carotid angiograms provide absolute c...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/1746-160X-4-20
更新日期：2008-08-26 00:00:00
abstract：INTRODUCTION:It has been shown that Low Level Laser (LLL) has a positive effect on bone formation. The aim of this study was to evaluate the effect of low level laser on condylar growth during mandibular advancement in rabbits. MATERIALS AND METHODS:Continuous forward mandibular advancement was performed in fourteen m...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/1746-160X-8-4
更新日期：2012-02-23 00:00:00
abstract：BACKGROUND:To report the outcome of guided endodontic treatment (GET) of a case of dentin dysplasia with pulp canal calcification (PCC) and apical periodontitis based on the use of a 3D-printed template designed by merging cone-beam computed tomography (CBCT) and surface scan data. CASE PRESENTATION:A 12-year old fema...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/s13005-020-00240-4
更新日期：2020-11-17 00:00:00
abstract：BACKGROUND:Ablative tumor surgery often results in continuity defects of the mandible. When an immediate reconstruction using autologous bone grafts is not possible the bridging of the defects with a variety of bridging plates might be achieved. However, those bridging plates have the risk of plate fractures or exposur...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/s13005-016-0114-0
更新日期：2016-04-11 00:00:00
abstract：:We describe a case of adenomatoid odontogenic tumor (AOT) associated with odontoma occurring in the posterior mandible of a 32-year-old man. Although calcifications are commonly found in the AOT, the presence of rudimentary dental structures is a very rare phenomenon. Cases with similar aspects have been described as ...
journal_title：Head & face medicine
pub_type： 杂志文章,评审
doi：10.1186/1746-160X-9-20
更新日期：2013-08-09 00:00:00
abstract：BACKGROUND:Schwannomas are uncommon benign tumors of the external auditory canal. The clinical features, the differential diagnosis, and the surgical treatment of these lesions are discussed. CASE PRESENTATION:A 51-year-old patient presented with a mass obliterating the external auditory meatus. Excisional biopsy was ...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/1746-160X-3-6
更新日期：2007-01-15 00:00:00
abstract：:Potential applications for gene-based tissue engineering therapies in the oral and maxillofacial complex include the delivery of growth factors for periodontal regeneration, pulp capping/dentin regeneration, and bone grafting of large osseous defects in dental and craniofacial reconstruction. Part 1 reviewed the princ...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/1746-160X-2-16
更新日期：2006-05-25 00:00:00
abstract：BACKGROUND:Successful treatment of patients with multiple bilateral impactions can be an orthodontic challenge, but few reports on treatment planning and execution exist. CASE PRESENTATION:In this case report, we describe the successful orthodontic treatment of a 16.3-year old female patient without systemic or geneti...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/s13005-016-0122-0
更新日期：2016-07-25 00:00:00
abstract：INTRODUCTION:The aim of this study was to compare the shear bond strength of Biodentine, ProRoot MTA (MTA), glass ionomer cement (GIC) and composite resin (CR) on dentine. METHODS:120 extracted human third molars were embedded in cold-cured-resin and grinned down to the dentine. For each material 30 specimens were pro...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/s13005-015-0071-z
更新日期：2015-04-19 00:00:00
abstract：BACKGROUND:Oral Health-Related Quality of Life (OHRQoL) is an important aspect of quality of life. Acute illnesses, as well as chronic diseases, can have a strong, persisting impact on an individual's quality of life. This study evaluates OHRQoL of patients with odontogenic fascial space abscesses, the underlying condi...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/s13005-019-0201-0
更新日期：2019-06-21 00:00:00
abstract：BACKGROUND:Langerhans cell histiocytosis (LCH), previously known as Histiocytosis X, is an infrequent disease that congregates a wide spectrum of clinical presentations with variable systemic involvement. Unification of these diseases under only one category is based on the almost identical histopathologic features of ...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/s13005-016-0118-9
更新日期：2016-06-02 00:00:00
abstract：:The traumatic bone cyst (TBC) is an uncommon nonepithelial lined cavity of the jaws. The lesion is mainly diagnosed in young patients most frequently during the second decade of life. The majority of TBCs are located in the mandibular body between the canine and the third molar. Clinically, the lesion is asymptomatic ...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/1746-160X-2-40
更新日期：2006-11-12 00:00:00
abstract：BACKGROUND:Hyperbaric oxygen (HBO) therapy is an effective adjunct treatment for ischemic disorders such as chronic infection or chronic wounds. It combines hyperoxic effects with the stimulating potential of post-therapeutic reactive hypoxia. As its crucial effects, stimulation of fibroblast growth, induction of colla...
journal_title：Head & face medicine
pub_type： 临床试验,杂志文章
doi：10.1186/1746-160X-6-29
更新日期：2010-12-22 00:00:00
abstract：BACKGROUND:Orthodontic treatment with fixed appliances requires - among others - the correct clinical expression of torque, which depends on the precise fitting of archwire and slot. Especially in the lingual technique torque problems become clinically more evident than in labial appliances also with respect to the ver...
journal_title：Head & face medicine
pub_type： 杂志文章
doi：10.1186/1746-160X-5-27
更新日期：2009-12-15 00:00:00
