Respiratory tract mortality in cement workers: a proportionate mortality study.

abstract：BACKGROUND:Reduced lung function in patients with chronic obstructive pulmonary disease (COPD) is likely due to both environmental and genetic factors. We report here a targeted high-throughput DNA sequencing approach to identify new and previously known genetic variants in a set of candidate genes for COPD. METHODS:E...

journal_title：BMC pulmonary medicine

authors： Matsson H,Söderhäll C,Einarsdottir E,Lamontagne M,Gudmundsson S,Backman H,Lindberg A,Rönmark E,Kere J,Sin D,Postma DS,Bossé Y,Lundbäck B,Klar J

更新日期：2016-11-11 00:00:00

abstract：BACKGROUND:The aim of this substudy of the ghrelin treatment, multicenter, randomized, double-blind, placebo-controlled trial was to investigate the effects of ghrelin administration on exercise capacity and the underlying mechanisms in underweight patients with chronic obstructive pulmonary disease (COPD) using cardio...

journal_title：BMC pulmonary medicine

authors： Miki K,Maekura R,Nagaya N,Kitada S,Miki M,Yoshimura K,Tateishi Y,Motone M,Hiraga T,Mori M,Kangawa K

更新日期：2013-06-10 00:00:00

abstract：BACKGROUND:Asthma is a common chronic disease among young adults, and several studies have reported increased mortality rates in patients with asthma. However, no study has described sudden unexpected death in a nationwide setting in patients with uncontrolled asthma. We defined uncontrolled asthma as a previous hospit...

journal_title：BMC pulmonary medicine

authors： Gullach AJ,Risgaard B,Lynge TH,Jabbari R,Glinge C,Haunsø S,Backer V,Winkel BG,Tfelt-Hansen J

更新日期：2015-04-14 00:00:00

abstract：BACKGROUND:Breathlessness is a common and distressing symptom affecting many patients with advanced disease both from malignant and non-malignant origin. A combination of pharmacological and non-pharmacological measures is necessary to treat this symptom successfully. Breathlessness services in various compositions aim...

journal_title：BMC pulmonary medicine

authors： Bausewein C,Jolley C,Reilly C,Lobo P,Kelly J,Bellas H,Madan P,Panell C,Brink E,De Biase C,Gao W,Murphy C,McCrone P,Moxham J,Higginson IJ

更新日期：2012-09-19 00:00:00

abstract：BACKGROUND:Diagnosis of lower respiratory tract infections (LRTI) depends on the presence of clinical, radiological and microbiological findings. Endotracheal suction aspirate (ETSA) is the commonest respiratory sample sent for culture from intubated patients. Very few studies have compared quantitative and semi-quanti...

journal_title：BMC pulmonary medicine

authors： Rattani S,Farooqi J,Jabeen G,Chandio S,Kash Q,Khan A,Jabeen K

更新日期：2020-10-29 00:00:00

abstract：BACKGROUND:Penicillium species are among the most common fungi present in the environment and are usually considered non-pathogenic to humans. However, in immunocompromised hosts they can be virulent pathogens and can cause death. Penicillium digitatum is a plant pathogen that commonly causes a postharvest fungal disea...

journal_title：BMC pulmonary medicine

authors： Oshikata C,Tsurikisawa N,Saito A,Watanabe M,Kamata Y,Tanaka M,Tsuburai T,Mitomi H,Takatori K,Yasueda H,Akiyama K

更新日期：2013-03-23 00:00:00

abstract：BACKGROUND:Telehealth and telemonitoring is an emerging area of study in people with cystic fibrosis (CF), with the potential of increasing access to care, and minimising infection control risks to patients without compromising their health outcomes. To date, limited evidence is available to support the use of teleheal...

journal_title：BMC pulmonary medicine

authors： Lang RL,Wilson C,Stockton K,Russell T,Johnston LM

更新日期：2019-01-24 00:00:00

abstract：BACKGROUND:The tissue factor (TF)-dependent extrinsic pathway has been suggested to be a central mechanism by which the coagulation cascade is locally activated in the lungs of patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS) and thus represents an attractive target for therapeutic int...

journal_title：BMC pulmonary medicine

authors： Morris PE,Steingrub JS,Huang BY,Tang S,Liu PM,Rhode PR,Wong HC

更新日期：2012-02-16 00:00:00

abstract：BACKGROUND:Compared to other pulmonary function tests, there is a lack of standardization regarding how a maximum voluntary ventilation (MVV) maneuver is performed. Specifically, little is known about the variation in breathing frequency (fR) and its potential impact on the accuracy of test results. This study examines...

journal_title：BMC pulmonary medicine

authors： Neufeld EV,Dolezal BA,Speier W,Cooper CB

更新日期：2018-05-24 00:00:00

abstract：BACKGROUND:Treatment of patients with Cystic Fibrosis homozygous for the Phe508del gene, with Lumacaftor /Ivacaftor (LUM/IVA) improves outcomes in patients with FEV1 > 40% predicted. We set out to observe the most sensitive clinical measure that would change with treatment in terms of exercise capacity or lung function...

journal_title：BMC pulmonary medicine

authors： Wark PAB,Cookson K,Thiruchelvam T,Brannan J,Dorahy DJ

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:Onset of allergic asthma has a strong association with childhood but only a few studies have analyzed incidence of asthma from childhood to late adulthood in relation to allergy. The purpose of the study was to assess age-specific incidence of allergic and non-allergic asthma. METHODS:Questionnaires were se...

journal_title：BMC pulmonary medicine

authors： Pakkasela J,Ilmarinen P,Honkamäki J,Tuomisto LE,Andersén H,Piirilä P,Hisinger-Mölkänen H,Sovijärvi A,Backman H,Lundbäck B,Rönmark E,Kankaanranta H,Lehtimäki L

更新日期：2020-01-10 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a disease with poor prognosis mainly affecting males. Differences in clinical presentation between genders may be important both for the diagnostic work-up and for follow-up. In the present study, we therefore explored potential gender differences at presentation in a S...

journal_title：BMC pulmonary medicine

authors： Kalafatis D,Gao J,Pesonen I,Carlson L,Sköld CM,Ferrara G

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:Programmed cell death 5 (PDCD5) was first identified as an apoptosis-promoting protein and involved in some autoimmune diseases and inflammatory processes. Our previous study demonstrated greater expression of serum PDCD5 in asthmatic patients than controls. This study aimed to further explore the significan...

journal_title：BMC pulmonary medicine

authors： Diao X,Wang J,Zhu H,He B

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities. The main causes of COPD are Gene-environment interactions associated with tobacco smoking (COPD-TS) and biomass smoke (COPD-BS). It is w...

journal_title：BMC pulmonary medicine

authors： Velasco-Torres Y,Ruiz-López V,Pérez-Bautista O,Buendía-Roldan I,Ramírez-Venegas A,Pérez-Ramos J,Falfán-Valencia R,Ramos C,Montaño M

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:Pneumonia poses a significant burden to the U.S. health-care system. However, there are few data focusing on severe pneumonia, particularly cases of pneumonia associated with specialized care in intensive care units (ICU). METHODS:We used administrative and electronic medical record data from six integrated...

journal_title：BMC pulmonary medicine

authors： Storms AD,Chen J,Jackson LA,Nordin JD,Naleway AL,Glanz JM,Jacobsen SJ,Weintraub ES,Klein NP,Gargiullo PM,Fry AM

更新日期：2017-12-16 00:00:00

abstract：BACKGROUND:The dysfunction of airway epithelial barrier is closely related to the pathogenesis of asthma. Secreted Hsp90α participates in inflammation and Hsp90 inhibitor protects endothelial dysfunction. In the current study, we aimed to explore the role of secreted Hsp90α in asthmatic airway epithelial barrier functi...

journal_title：BMC pulmonary medicine

authors： Ye C,Huang C,Zou M,Hu Y,Luo L,Wei Y,Wan X,Zhao H,Li W,Cai S,Dong H

更新日期：2019-11-20 00:00:00

abstract：BACKGROUND:Physical training has been shown to improve exercise capabilities in patients with asthma. Most studies focused on children and younger adults. Previously, the maximum program duration was six months. It is not known whether the same results may be obtained with lower intensity programs and sustained for tim...

journal_title：BMC pulmonary medicine

authors： Meyer A,Günther S,Volmer T,Taube K,Baumann HJ

更新日期：2015-05-07 00:00:00

abstract：BACKGROUND:The ability to objectively differentiate exacerbations of chronic obstructive pulmonary disease (COPD) from day-to-day symptom variations would be an important development in clinical practice and research. We assessed the ability of domiciliary pulse oximetry to achieve this. METHODS:40 patients with moder...

journal_title：BMC pulmonary medicine

authors： Hurst JR,Donaldson GC,Quint JK,Goldring JJ,Patel AR,Wedzicha JA

更新日期：2010-10-20 00:00:00

abstract：BACKGROUND:Many studies have investigated whether pleural cholesterol levels can aid in diagnosis of pleural exudates, and the results have varied considerably. To gain a more reliable answer to this question, we meta-analyzed the literature on using pleural cholesterol or the ratio of cholesterol in pleural fluid to c...

journal_title：BMC pulmonary medicine

authors： Shen Y,Zhu H,Wan C,Chen L,Wang T,Yang T,Wen F

更新日期：2014-04-15 00:00:00

abstract：BACKGROUND:In Europe, administration of an inhaled corticosteroid (ICS) combined with a long-acting β2 agonist is approved in chronic obstructive pulmonary disease (COPD) patients with a pre-bronchodilator FEV1 < 60% predicted normal, a history of repeated exacerbations, and who have significant symptoms despite regula...

journal_title：BMC pulmonary medicine

authors： Roche N,Pribil C,Van Ganse E,Serrier P,Housset B,Poirier D,Texier N,Schück S,Boucot I

更新日期：2014-04-02 00:00:00

abstract：BACKGROUND:A recent method determines regional gas flow of the lung by electrical impedance tomography (EIT). The aim of this study is to show the applicability of this method in a porcine model of mechanical ventilation in healthy and diseased lungs. Our primary hypothesis is that global gas flow measured by EIT can b...

journal_title：BMC pulmonary medicine

authors： Bodenstein M,Boehme S,Bierschock S,Vogt A,David M,Markstaller K

更新日期：2014-04-29 00:00:00

abstract：BACKGROUND:Hypoxemia is a major complication of COPD and is a strong predictor of mortality. We previously identified independent risk factors for the presence of resting hypoxemia in the COPDGene cohort. However, little is known about characteristics that predict onset of resting hypoxemia in patients who are normoxic...

journal_title：BMC pulmonary medicine

authors： Wells JM,Estepar RS,McDonald MN,Bhatt SP,Diaz AA,Bailey WC,Jacobson FL,Dransfield MT,Washko GR,Make BJ,Casaburi R,van Beek EJ,Hoffman EA,Sciurba FC,Crapo JD,Silverman EK,Hersh CP,COPDGene Investigators.

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is combination of progressive lung diseases. The diagnosis of COPD is generally based on the pulmonary function testing, however, difficulties underlie in prognosis of smokers or early stage of COPD patients due to the complexity and heterogeneity of the pathogene...

journal_title：BMC pulmonary medicine

authors： Matsumura K,Ito S

更新日期：2020-02-03 00:00:00

abstract：BACKGROUND:The early diagnosis of non-small cell lung cancer is of great significance to the prognosis of patients. However, traditional histopathology and imaging screening have certain limitations. Therefore, new diagnostical methods are urgently needed for the current clinical diagnosis. In this study we evaluated t...

journal_title：BMC pulmonary medicine

authors： Li J,Liao Y,Ran Y,Wang G,Wu W,Qiu Y,Liu J,Wen N,Jing T,Wang H,Zhang S

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:The assessment of airway inflammation for the diagnosis of asthma or COPD is still uncommon in pneumology-specialized general practices. In this respect, the measurement of exhaled nitric oxide (NO), as a fast and simple methodology, is increasingly used. The indirect assessment of airway inflammation, howev...

journal_title：BMC pulmonary medicine

authors： Holz O,Seiler T,Karmeier A,Fraedrich J,Leiner H,Magnussen H,Jörres RA,Welker L

更新日期：2008-02-28 00:00:00

abstract：BACKGROUND:The use of extracorporeal membrane oxygenation (ECMO) in awake, spontaneously breathing and non-intubated patients (awake ECMO) may be a novel therapeutic strategy for severe acute respiratory distress syndrome (ARDS) patients. The purpose of this study is to assess the feasibility and safety of awake ECMO i...

journal_title：BMC pulmonary medicine

authors： Xia J,Gu S,Li M,Liu D,Huang X,Yi L,Wu L,Fan G,Zhan Q

更新日期：2019-12-09 00:00:00

abstract：BACKGROUND:Air pollution has many negative health effects on the general population, especially children, subjects with underlying chronic disease and the elderly. The aims of this study were to evaluate the effects of traffic-related pollution on the exacerbation of asthma and development of respiratory infections in ...

journal_title：BMC pulmonary medicine

authors： Esposito S,Galeone C,Lelii M,Longhi B,Ascolese B,Senatore L,Prada E,Montinaro V,Malerba S,Patria MF,Principi N

更新日期：2014-08-07 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) with carbon dioxide retention is associated with a worsening clinical condition and the beginning of pulmonary ventilation decompensation. This study aimed to identify the factors associated with carbon dioxide retention. METHODS:This was a retrospective study of...

journal_title：BMC pulmonary medicine

authors： Wei X,Yu N,Ding Q,Ren J,Mi J,Bai L,Li J,Qi M,Guo Y

更新日期：2018-07-31 00:00:00

abstract：BACKGROUND:The 2013 GOLD classification system for COPD distinguishes four stages: A (low symptoms, low exacerbation risk), B (high symptoms, low risk), C (low symptoms, high risk) and D (high symptoms, high risk). Assessment of risk is based on exacerbation history and airflow obstruction, whatever results in a higher...

journal_title：BMC pulmonary medicine

authors： Goossens LM,Leimer I,Metzdorf N,Becker K,Rutten-van Mölken MP

更新日期：2014-10-18 00:00:00

abstract：BACKGROUND:US mentholated cigarette sales have increased considerably over 50 years. Preference for mentholated cigarettes is markedly higher in Black people. While menthol itself is not genotoxic or carcinogenic, its acute respiratory effects might affect inhalation of cigarette smoke. This possibility seems consisten...

journal_title：BMC pulmonary medicine

authors： Lee PN

更新日期：2011-04-18 00:00:00