Effect of pepper and bismuth subsalicylate on gastric pain and surface hydrophobicity in the rat.

abstract：BACKGROUND:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19), became a global threat to human health. Liver impairment has been frequently reported as a common manifestation, although its clinical significance is still unclear, particularly in pa...

journal_title：Alimentary pharmacology & therapeutics

authors： Garrido I,Liberal R,Macedo G

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Data on whether long-acting somatostatin analogue octreotide causes or prevents pancreatic injury following endoscopic retrograde cholangiopancreatography (ERCP) are controversial. AIM:This multicentre, prospective trial studied the effect of octreotide on pancreatic injury in a large unselected group of pa...

journal_title：Alimentary pharmacology & therapeutics

authors： Tulassay Z,Döbrönte Z,Prónai L,Zágoni T,Juhász L

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Faecal calprotectin and lactoferrin increasingly serve as surrogate markers of disease activity in IBD. Data on the correlation of these markers with simple endoscopic score for Crohn's disease (SES-CD) and with histological findings are as yet limited. Aim To study the correlation of faecal calprotectin and...

journal_title：Alimentary pharmacology & therapeutics

authors： Sipponen T,Kärkkäinen P,Savilahti E,Kolho KL,Nuutinen H,Turunen U,Färkkilä M

更新日期：2008-11-15 00:00:00

abstract：BACKGROUND:The efficacy of cyclosporin in the management of ulcerative colitis is recognized. Not all patients respond to this treatment. Existing clinical and laboratory parameters are of little use in identifying those most likely to respond. AIMS:To determine whether in-vitro sensitivity to cyclosporin as measured ...

journal_title：Alimentary pharmacology & therapeutics

authors： McCormack G,O'Donoghue D,Baird A

更新日期：2001-05-01 00:00:00

abstract：:This review summarizes the clinical evidence to support current therapies in irritable bowel syndrome (IBS). Fibre is indicated at a dose of at least 12 g per day in patients with constipation-predominant IBS. Loperamide (and probably other opioid agonists) are of proven benefit in diarrhoea-predominant IBS; loperamid...

journal_title：Alimentary pharmacology & therapeutics

authors： Camilleri M

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Infliximab reduces mucosal inflammation in some, but not all, patients with Crohn's disease. AIM:To monitor clinical data and changes in mucosal cytokine levels after infliximab treatment to identify differences between responders and non-responders. METHODS:Twenty-six patients with fistulating Crohn's dis...

journal_title：Alimentary pharmacology & therapeutics

authors： Agnholt J,Dahlerup JF,Buntzen S,Tøttrup A,Nielsen SL,Lundorf E

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Pregabalin has a broad spectrum of analgesic and antihyperalgesic activity in both basic and clinical studies. However, its mechanisms and sites of action have yet to be determined in humans. AIMS:To assess the antinociceptive effect of pregabalin on experimental gut pain in patients with visceral hyperalge...

journal_title：Alimentary pharmacology & therapeutics

authors： Olesen SS,Graversen C,Olesen AE,Frøkjaer JB,Wilder-Smith O,van Goor H,Valeriani M,Drewes AM

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Dexlansoprazole MR is a Dual Delayed Release formulation of dexlansoprazole, an enantiomer of lansoprazole, designed to extend the duration of acid suppression. AIM:To assess the 12-month safety of dexlansoprazole MR in patients with symptomatic gastro-oesophageal reflux disease (GERD). METHODS:In this ran...

journal_title：Alimentary pharmacology & therapeutics

authors： Dabholkar AH,Han C,Paris MM,Perez MC,Atkinson SN,Peura DA

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:[corrected] A predictable consequence of cholestasis is malabsorption of fat-soluble factors, (vitamins A, D, E, K) and other free radical scavengers, such as carotenoids. It has been suggested that oxygen-derived free radicals may be involved in the pathogenesis of chronic liver damage. AIMS:(i) To evaluat...

journal_title：Alimentary pharmacology & therapeutics

authors： Floreani A,Baragiotta A,Martines D,Naccarato R,D'odorico A

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Clostridium difficile (C. difficile) infection in hospitals in developed countries continues to be a major public health hazard despite increased control measures including review of antibiotic policies and hygiene measures. Patients with colitis are thought to be particularly vulnerable to C. difficile asso...

journal_title：Alimentary pharmacology & therapeutics

authors： Jen MH,Saxena S,Bottle A,Aylin P,Pollok RC

更新日期：2011-06-01 00:00:00

abstract：:The study investigated the oral absorption of two antifungal agents, fluconazole and itraconazole, under conditions of low intragastric acidity. Twelve healthy male volunteers received each of 4 dosing regimens: 200 mg itraconazole alone, 200 mg itraconazole and famotidine, 100 mg fluconazole alone, and 100 mg flucona...

journal_title：Alimentary pharmacology & therapeutics

authors： Lim SG,Sawyerr AM,Hudson M,Sercombe J,Pounder RE

更新日期：1993-06-01 00:00:00

abstract：:More than 15 years after the launch of omeprazole in 1988, proton-pump inhibitors remain central to the management of acid-suppression disorders and are unchallenged with regard to their efficacy and popularity among doctors and patients. They are considered safe despite early concerns about the possibility of an asso...

journal_title：Alimentary pharmacology & therapeutics

authors： Raghunath AS,O'Morain C,McLoughlin RC

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Travellers' diarrhoea, a common problem worldwide with significant medical impact, is generally treated with anti-diarrhoeal agents and fluid replacement. Systemic antibiotics are also used in selected cases, but these may be associated with adverse effects, bacterial resistance and drug-drug interactions. ...

journal_title：Alimentary pharmacology & therapeutics

authors： Layer P,Andresen V

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Peginterferon-alpha-based therapy frequently leads to neutropenia. It remains unclear whether neutropenia is associated with bacterial infection in chronic hepatitis C (CHC). AIM:To evaluate the risk of bacterial infection and neutropenia in patients with CHC treated with peginterferon-alpha/ribavirin. MET...

journal_title：Alimentary pharmacology & therapeutics

authors： Yang JF,Hsieh MY,Hou NJ,Dai CY,Huang JF,Lin ZY,Chen SC,Hsieh MY,Wang LY,Chuang WL,Yu ML

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Strong suppression of viral replication and normalization of alanine aminotransferase is feasible with nucleos(t)ide analogues. It is estimated viral replication and liver inflammation can be controlled in 90% of patients with chronic hepatitis B with the current available treatments. AIM:To review the stud...

journal_title：Alimentary pharmacology & therapeutics

authors： Leemans WF,Ter Borg MJ,de Man RA

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:The most common complication after ileal pouch anal anastomosis in up to 50% of patients is an acute pouchitis. The majority of patients respond to antibiotic treatment. However, 10%-15% develops chronic antibiotic-dependent or refractory pouchitis which is usually hard to treat. AIM:To evaluate the effecti...

journal_title：Alimentary pharmacology & therapeutics

authors： Bär F,Kühbacher T,Dietrich NA,Krause T,Stallmach A,Teich N,Schreiber S,Walldorf J,Schmelz R,Büning C,Fellermann K,Büning J,Helwig U,German IBD Study Group.

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Alginates form a raft above the gastric contents, which may suppress gastro-oesophageal reflux; however, inconsistent effects have been reported in mechanistic and clinical studies. AIMS:To visualise reflux suppression by an alginate-antacid [Gaviscon Advance (GA), Reckitt Benckiser, UK] compared with a non...

journal_title：Alimentary pharmacology & therapeutics

authors： Sweis R,Kaufman E,Anggiansah A,Wong T,Dettmar P,Fried M,Schwizer W,Avvari RK,Pal A,Fox M

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Radiotherapy is an established treatment modality for prostate cancer; however, up to a third of patients develops a radiation-induced proctopathy. AIM:To assess the effect of topical beclomethasone dipropionate (BDP) in the prevention of radiation-induced proctopathy in patients undergoing radiotherapy for...

journal_title：Alimentary pharmacology & therapeutics

authors： Fuccio L,Guido A,Laterza L,Eusebi LH,Busutti L,Bunkheila F,Barbieri E,Bazzoli F

更新日期：2011-09-01 00:00:00

abstract：AIM:To assess the efficacy of the 8-week therapy with esomeprazole 40 mg vs. pantoprazole 40 mg for healing erosive oesophagitis (EE) as part of a management study. METHODS:Patients had a history of gastro-oesophageal reflux disease symptoms (> or =6 months) and had suffered heartburn on at least 4 of the 7 days prece...

journal_title：Alimentary pharmacology & therapeutics

authors： Labenz J,Armstrong D,Lauritsen K,Katelaris P,Schmidt S,Schütze K,Wallner G,Juergens H,Preiksaitis H,Keeling N,Nauclér E,Eklund S,Expo Study Investigators.

更新日期：2005-03-15 00:00:00

abstract：BACKGROUND:There is no consensus on the standard treatment of gastric mucosa-associated lymphoid tissue (MALT) lymphoma for Helicobacter pylori-negative patients and for patients with persistent disease despite H. pylori eradication. AIM:To evaluate the comparative efficacy and safety of alkylating agents and rituxima...

journal_title：Alimentary pharmacology & therapeutics

authors： Amiot A,Lévy M,Copie-Bergman C,Dupuis J,Szablewski V,Le Baleur Y,Baia M,Belhadj K,Sobhani I,Leroy K,Haioun C,Delchier JC

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Population-based data on gastro-oesophageal reflux in Latin America are lacking. AIM:To assess gastro-oesophageal reflux symptom prevalence, clinical spectrum and association with the atypical symptoms in our country. METHODS:Gastro-oesophageal reflux self-report questionnaires validated at Mayo Clinic, US...

journal_title：Alimentary pharmacology & therapeutics

authors： Chiocca JC,Olmos JA,Salis GB,Soifer LO,Higa R,Marcolongo M,ARGENTINEAN GASTRO-OESOPHAGEAL REFLUX STUDY GROUP.

更新日期：2005-08-15 00:00:00

abstract：:Upper gastrointestinal symptoms are highly prevalent; usually those consulting have multiple symptoms, confounding management. Here, common clinically relevant management issues are considered based on the best available evidence. Regardless of the presenting symptoms, determine if there are any alarm features; these ...

journal_title：Alimentary pharmacology & therapeutics

authors： Talley NJ

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Tacrolimus is a calcineurin inhibitor commonly used for prophylaxis of rejection in renal and liver transplantation. There are limited but favourable data regarding its possible use in patients with inflammatory bowel disease (IBD). AIMS:To evaluate the efficacy and safety of tacrolimus in patients with IBD...

journal_title：Alimentary pharmacology & therapeutics

authors： Rodríguez-Lago I,Castro-Poceiro J,Fernández-Clotet A,Mesonero F,López-Sanromán A,López-García A,Márquez L,Clos-Parals A,Cañete F,Vicuña M,Nantes Ó,Merino O,Matallana V,Gordillo J,Elorza A,Vicente R,Casanova MJ,Ferreiro-

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:There has been growing interest in the use of faecal microbiota transplantation (FMT) for the treatment of gastrointestinal and nongastrointestinal diseases. AIM:To review systematically the reported efficacy and safety of FMT in the management of gastrointestinal and nongastrointestinal disorders in adults...

journal_title：Alimentary pharmacology & therapeutics

authors： Sha S,Liang J,Chen M,Xu B,Liang C,Wei N,Wu K

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome is characterised by chronic abdominal pain and frequent comorbid anxiety. The substance P ⁄ neurokinin-1 receptor system is implicated in the regulation of both pain and anxiety, suggesting a potential therapeutic target in IBS. AIM:To determine whether inhibition of the neurokinin-...

journal_title：Alimentary pharmacology & therapeutics

authors： Tillisch K,Labus J,Nam B,Bueller J,Smith S,Suyenobu B,Siffert J,McKelvy J,Naliboff B,Mayer E

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:CXC chemokines such as interleukin (IL)-8 are neutrophil chemoattractants, the levels of which increase in Helicobacter pylori-infected gastric mucosa. Many investigators have focused on the chemotactic aspects of IL-8: however, CXC chemokines are also reported to have angiogenic activity and to serve as rem...

journal_title：Alimentary pharmacology & therapeutics

authors： Suzuki H,Mori M,Seto K,Shibata F,Nagahashi S,Kawaguchi C,Suzuki M,Matsui H,Watanabe K,Miura S,Ishii H

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Helicobacter-negative gastritis and duodenitis occur more often in patients with inflammatory bowel disease (IBD) than in non-IBD controls. Preliminary evidence suggests that they are particularly common among children. AIM:To study the age-specific occurrence of gastritis and duodenitis among paediatric IB...

journal_title：Alimentary pharmacology & therapeutics

authors： Genta RM,Sonnenberg A

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Data on liver transplantation (LT) in acute on chronic liver failure (ACLF) are scanty. AIM:To perform meta-analysis on outcomes after LT for ACLF compared with ACLF patients not receiving LT or with LT recipients for indications other than ACLF. METHODS:We pooled data from 12 studies on LT outcomes among ...

journal_title：Alimentary pharmacology & therapeutics

authors： Abdallah MA,Waleed M,Bell MG,Nelson M,Wong R,Sundaram V,Singal AK

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Twice-daily dosing is increasingly used to improve gastric acid control, although not all proton-pump inhibitors are more effective when doses are split. Standard dose esomeprazole provides better gastric acid control than other standard dose proton-pump inhibitors. AIMS:To compare the effect of standard do...

journal_title：Alimentary pharmacology & therapeutics

authors： Hammer J,Schmidt B

更新日期：2004-05-15 00:00:00

abstract：BACKGROUND:Pancreatic exocrine insufficiency (PEI) results in maldigestion, leading to abdominal pain, steatorrhoea, malnutrition and weight loss. AIM:To assess the efficacy and safety of pancreatin (Creon 40000 MMS) in treating PEI due to chronic pancreatitis (CP). METHODS:This was a 1-week, double-blind, randomised...

journal_title：Alimentary pharmacology & therapeutics

authors： Thorat V,Reddy N,Bhatia S,Bapaye A,Rajkumar JS,Kini DD,Kalla MM,Ramesh H

更新日期：2012-09-01 00:00:00