Abstract:
:HLA-B27 is a transplantation antigen found in a high proportion of patients with ankylosing spondylitis. Recently, an association has been shown to exist between HLA-B27 and acute uveitis, even in the absence of ankylosing spondylitis. We have examined the HLA antigen profile of 45 patients with acute nongranulomatous anterior uveitis and have confirmed this relation. In addition, using 90mtechnetium stannous pyrophosphate we have been able to demonstrate abnormal bone scan in 19 of 30 patients studied. Such abnormalities are limited to the sacroiliac joints but are otherwise the same as those seen in overt ankylosing spondylitis. Seven of the 19 patients did not have HLA-B27. These factors suggest that acute anterior uveitis may often represent a manifestation of a spondylitic diathesis even in the complete absence of any suggestive symptomatic or radiologic change and, in some cases, even though the antigenic marker HLA-B27 may be absent.
journal_name
Ann Intern Medjournal_title
Annals of internal medicineauthors
Russell AS,Lentle BC,Percy JS,Jackson FIdoi
10.7326/0003-4819-85-5-606subject
Has Abstractpub_date
1976-11-01 00:00:00pages
606-8issue
5eissn
0003-4819issn
1539-3704journal_volume
85pub_type
杂志文章abstract:DESCRIPTION:The Women's Preventive Services Initiative (WPSI), a national coalition of women's health professional organizations and patient representatives, developed a recommendation on screening for anxiety in adolescent and adult women to improve detection; achieve earlier diagnosis and treatment; and improve healt...
journal_title:Annals of internal medicine
pub_type: 杂志文章,实务指引
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journal_title:Annals of internal medicine
pub_type: 杂志文章,meta分析,评审
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更新日期:2015-08-04 00:00:00
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journal_title:Annals of internal medicine
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2014-03-18 00:00:00
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更新日期:2011-04-19 00:00:00
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journal_title:Annals of internal medicine
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更新日期:2013-02-05 00:00:00
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更新日期:2006-02-21 00:00:00
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journal_title:Annals of internal medicine
pub_type: 杂志文章,评审
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更新日期:1996-07-01 00:00:00
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更新日期:1999-06-15 00:00:00
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更新日期:1998-06-01 00:00:00