Endoscopic creation of reflux in the pig.

Abstract:

:Vesicoureteral reflux (VUR) in the animal model for experimental purposes can be created either by open transvesical or endoscopic techniques. The concept of reflux creation is the same for both techniques: incision of the roof of the intramural portion of the ureter at the 12 o'clock position. The open method has the disadvantages of requiring a cystotomy and a lengthy healing period prior to initiating a study, thereby incurring additional expense and the problem of introducing several confounding factors. The open method is unreliable because of the resolution of reflux over time. Herein, we present a simple transurethral endoscopic technique for creating VUR in pigs. This technique was successful in producing persistent Grade II or III reflux in 94% of the incised ureters.

journal_name

J Endourol

journal_title

Journal of endourology

authors

Elbahnasy AM,Shalhav AL,Hoenig DM,Maxwell K,Figenshau RS,McDougall EM,Clayman RV

doi

10.1089/end.1998.12.41

subject

Has Abstract

pub_date

1998-02-01 00:00:00

pages

41-4

issue

1

eissn

0892-7790

issn

1557-900X

journal_volume

12

pub_type

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