Blood flow in a chronic entrapment neuropathy model in the rabbit sciatic nerve.

Abstract:

:A model of chronic entrapment neuropathy in the rabbit sciatic nerve was developed to try to elucidate the pathogenesis of chronic nerve entrapment. A non-compressive Silastic cuff was wrapped around the nerve at the mid-thigh level in eight rabbits. A sham operation that only elevated the sciatic nerve was performed in seven control rabbits. Six months later, the blood flow in the cuffed and the control sciatic nerves was determined with intra-arterially injected microspheres. Blood flow was significantly reduced in the entrapped nerve, compared to control nerves, but only in the segment proximal to the cuff. After surgical release of the cuff, the blood flow significantly increased in the proximal segment. This suggested that decreased blood flow may occur, but not necessarily at the site of nerve entrapment. Nerve conduction velocity changes were also consistent with an entrapment neuropathy. However, there were no significant quantitative morphometric changes at the nerve entrapment site, that is, in myelin thickness/nerve diameter ratio, distribution of axon sizes, and mean nerve fiber diameter. This indicates that only a mild entrapment was created.

journal_name

J Reconstr Microsurg

authors

Aziz W,Firrell JC,Ogden L,Breidenbach WC

doi

10.1055/s-2007-1000070

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

47-53

issue

1

eissn

0743-684X

issn

1098-8947

journal_volume

15

pub_type

杂志文章
  • A review of local and regional flaps for distal leg reconstruction.

    abstract::Reconstruction of defects or wounds of the distal third of the leg with exposed bone, tendon, or hardware is challenging. Free tissue transfer has allowed limb salvage in many cases but requires a relatively healthy and stable patient, long operative times, and a significant expense. Small and moderate-size wounds of ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章,评审

    doi:10.1055/s-0029-1223847

    authors: Parrett BM,Talbot SG,Pribaz JJ,Lee BT

    更新日期:2009-09-01 00:00:00

  • Functional limb salvage combining gastrocnemius neurotization and posterior tibial nerve grafting: a case report.

    abstract::Functional limb salvage requires motor and sensory reconstruction of the extremity. An avulsion of the tibial nerve in the popliteal fossa after arthroscopy is presented. Functional limb recovery necessitated intraoperative nerve mapping by awake stimulation, neurotization of the gastrocnemius muscle bellies, and inte...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2007-1006702

    authors: Francel TJ,Dellon AL

    更新日期:1992-05-01 00:00:00

  • Multiple vascular anastomoses with vein grafts for salvage of congestive flaps.

    abstract::The authors present two cases in which the venous drainage of transferred flaps was compromised and the flaps were salvaged by vein grafts. Traditionally, once transferred free flaps had become congestive, surgeons would re-anastomose the thrombosed veins, and administer anticoagulants or carry out peripheral vessel d...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2004-815639

    authors: Namba Y,Takahashi Y,Ito S,Koshima I

    更新日期:2003-11-01 00:00:00

  • Microsurgical reconstruction during the early puerperium.

    abstract::A transverse rectus abdominis musculocutaneous free flap was electively performed for reconstructing the cutaneous cover in a patient during the early puerperium (12 hr after delivery). This flap was chosen because of the natural expansion achieved by pregnancy, and because it would cover the entire area to be reconst...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2007-1006478

    authors: Iglesias M,Butrón P,Granados R

    更新日期:1996-05-01 00:00:00

  • Microsurgical training with surgical gauze: the first step.

    abstract::To assist nascent microsurgeons in the initial practices of handling instruments and tying knots before using an animal model, the authors discuss surgical gauze, which will be of benefit to all trainees. In this model, the nascent microsurgeon can familiarize himself or herself with the operating microscope, correct ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2003-42634

    authors: Demirseren ME,Tosa Y,Hosaka Y

    更新日期:2003-08-01 00:00:00

  • Outcomes of Subfascial, Suprafascial, and Super-Thin Anterolateral Thigh Flaps: Tailoring Thickness without Added Morbidity.

    abstract:BACKGROUND: Subfascial anterolateral thigh (ALT) flap thickness can be problematic with regards to bulk, oral competence, shoe-fit, or as a potential source of recurrent wound breakdown. We have utilized distinct upper thigh fascial planes to fashion thin (suprafascial) or super-thin (periscarpal) ALT flaps to improve ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-0037-1607426

    authors: Diamond S,Seth AK,Chattha AS,Iorio ML

    更新日期:2018-03-01 00:00:00

  • Acellular human dermal matrix as a small vessel substitute.

    abstract::In both vascular and microvascular surgery, there is a need for a non-thrombogenic, small-caliber, arterial substitute. Clinically, most vessel substitutes with diameters under 4 mm have low patency rates. An arterial conduit made from a biocompatible human acellular dermis may be useful as a small vessel conduit. The...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2007-1006491

    authors: Inoue Y,Anthony JP,Lleon P,Young DM

    更新日期:1996-07-01 00:00:00

  • Closure of big toe defects after wrap-around flap transfer using the arterialized venous flap.

    abstract::Sixteen arterialized venous flaps, free flaps that have arterial blood only flowing through the vein of the flap, were applied to reconstruct skin defects of the big toe resulting from wrap-around flap transfers. There were seven complete successes, six partial successes, and three complete failures. The clinical cour...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2007-1006756

    authors: Inoue G,Maeda N,Suzuki K

    更新日期:1991-01-01 00:00:00

  • Mechanical Allodynia Predicts Better Outcome of Surgical Decompression for Painful Diabetic Peripheral Neuropathy.

    abstract:BACKGROUND: To determine the role of mechanical allodynia (MA) in predicting good surgical outcome for painful diabetic peripheral neuropathy (DPN). MATERIALS AND METHODS: Data of 192 patients with painful DPN were collected in this study, with 148 surgical patients and 44 patients in the control group. Both groups we...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-0038-1636938

    authors: Liao C,Nickerson DS,Visocchi M,Yang M,Liu P,Zhong W,Zhou H,Zhang W

    更新日期:2018-07-01 00:00:00

  • Forequarter amputation wound coverage with an ipsilateral, lymphedematous, circumferential forearm fasciocutaneous free flap in patients undergoing palliative shoulder-girdle tumor resection.

    abstract::Closure of massive soft-tissue defects in patients undergoing forequarter amputation for shoulder-girdle tumors may present a daunting challenge. This report describes two patients whose forequarter amputations were closed using ipsilateral, lymphedematous, circumferential forearm fasciocutaneous free flaps. ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2007-1006658

    authors: Zachary LS,Gottlieb LJ,Simon M,Ferguson MK,Calkins E

    更新日期:1993-03-01 00:00:00

  • Double level amputation: should it be replanted?

    abstract::Multiple level amputation has been described as a contraindication to replantation. This is a case report of a patient with a double level amputation through the palm and forearm that was successfully replanted. Because of the need for multiple stages of reconstructive surgery, it was not clear until the end result th...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2007-1007016

    authors: Belsky MR,Ruby LK

    更新日期:1986-04-01 00:00:00

  • Treatment of a patient with small fiber pathology using nerve biopsy and grafting: a case report.

    abstract::Small fiber pathology is a common clinical entity with a variable clinical presentation and etiology. Unfortunately, little has been described regarding its treatment because a majority of cases are idiopathic. Hence, treatment often consists of symptomatic management of pain and autonomic dysfunction. This report des...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-0033-1349756

    authors: Peled ZM

    更新日期:2013-10-01 00:00:00

  • The Venous Lymph Node Flap: Concepts, Experimental Evidence, and Potential Clinical Implications.

    abstract::Background Traditionally, lymph node flaps (LNF) have been designed as arteriovenous flaps, with little attention given to the functional anatomy of lymphatic system included in the flap. Based on the anatomical and physiological features of lymphatic system, we believe that a new concept of LNF, the venous LNF, shoul...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-0036-1584527

    authors: Visconti G,Constantinescu T,Chen PY,Salgarello M,Franceschini G,Masetti R,Chen HC

    更新日期:2016-10-01 00:00:00

  • Posterior radial collateral artery as the basis of the lateral forearm flap.

    abstract::The lateral forearm flap is being increasingly used for covering minor-to-moderate-sized defects for which soft and thin skin is required. Within the framework of an anatomic study carried out on 28 cadaveric arms, the authors investigated the principal artery that supplies blood to this flap namely, the posterior rad...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2000-7537

    authors: Meirer R,Schrank C,Putz R

    更新日期:2000-01-01 00:00:00

  • The effect of ammonium sulfate injection on peripheral nerve.

    abstract::Local anesthetic drugs with prolonged nerve-block effect would have clinical application for postoperative or neuromatous pain relief. This study evaluated the possibility of peripheral nerve neurotoxicity by injection of 10 percent ammonium sulfate. Both intrafascicular and extrafascicular injection of 10 percent amm...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2007-1006418

    authors: Kobayashi J,Mackinnon SE,Langer JC,Hertl MC,Hunter DA,Tarasidis G

    更新日期:1997-08-01 00:00:00

  • Bridging critical nerve defects through an acellular homograft seeded with autologous schwann cells obtained from a regeneration neuroma of the proximal stump.

    abstract::Over the last decade, several models have investigated the usefulness of different biologic and/or synthetic matrices as alternatives to conventional nerve grafts. Still, axonal regeneration did not occur over longer (> 3 cm) distances. One problem may be that a growth-promoting environment not only includes physical ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2008-1076091

    authors: Aszmann OC,Korak KJ,Luegmair M,Frey M

    更新日期:2008-04-01 00:00:00

  • Single-stage maxillary and nasal floor reconstruction with the double-paddle rectus abdominis musculocutaneous free flap.

    abstract::Palatal integrity is essential for useful speech, deglutition, good oral hygiene, and prevention of nasal regurgitation. Maxillary defects after tumor extirpation, therefore, can have serious functional and cosmetic implications. Given the often disappointing results obtained with local and regional pedicled flaps for...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2007-974647

    authors: Herman CK,Benacquista T,Brindzei N,Berdichevsky M,Baum T,Strauch B

    更新日期:2007-04-01 00:00:00

  • Vascularized fibular grafting in the treatment of methicillin-resistant Staphylococcus aureus osteomyelitis and infected nonunion.

    abstract::Twenty patients with methicillin-resistant Staphylococcus aureus (MRSA) osteomyelitis and bone infection were treated with vascularized fibular grafts. There were 16 males and four females, and the patient ages at operation ranged from 17 to 73 years. Nine of the lesions affected the femur, eight the tibia, and there ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2004-818044

    authors: Yajima H,Kobata Y,Shigematsu K,Kawamura K,Kawate K,Tamai S,Takakura Y

    更新日期:2004-01-01 00:00:00

  • Flap monitoring by transcutaneous PO2 and PCO2: importance of transcutaneous PCO2 in determining follow-up treatment for compromised free flaps.

    abstract::The authors conducted a two-part study to determine whether transcutaneous oxygen pressure (TcPO (2)) and transcutaneous carbon dioxide pressure (TcPCO (2)) can be used to monitor flap viability after transplantation. The first part was an animal study in which TcPO (2) and TcPCO (2) were measured in 10 epigastric isl...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2007-985208

    authors: Hashimoto I,Nakanishi H,Takiwaki H,Takase MT,Yamano M,Sedo H

    更新日期:2007-07-01 00:00:00

  • Role of the target in end-to-side neurorrhaphy: reinnervation of a single muscle vs. multiple muscles.

    abstract::The authors examined the effects of end-to-side neurorrhaphy for reinnervation of the musculocutaneous nerve (Group A) which innervates the biceps muscle, compared to reinnervation of the median nerve which innervates multiple muscles in a rat model. Additionally, end-to-end neurorrhaphy to the musculocutaneous nerve ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2006-947151

    authors: Lutz BS,Ma SF,Chuang DC,Wei FC

    更新日期:2000-08-01 00:00:00

  • Direct neurotization of muscles by presynaptic motoneurons.

    abstract::The spinal cord cannot heal after severance because the central nervous system is "non-permissive" to the advancement of axons that regrow from presynaptic motoneurons. With the aim of overcoming paraplegia, the author has carried out extensive experimental research since 1980, first in rats and subsequently in monkey...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2001-18873

    authors: Brunelli GA

    更新日期:2001-11-01 00:00:00

  • Management of radial nerve injury associated with humeral shaft fractures: an evidence-based approach.

    abstract::Injury to the radial nerve is not uncommonly associated with fractures of the humerus. Despite a considerable amount of information and literature regarding management of these associated injuries, a universally accepted algorithm for treatment remains elusive. This article assimilates the data and provides evidence-b...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章,评审

    doi:10.1055/s-0028-1090623

    authors: Elton SG,Rizzo M

    更新日期:2008-11-01 00:00:00

  • Superficial ulnar artery: embryology, case report, and clinical significance in reconstructive microsurgery.

    abstract::In this paper the authors describe and illustrate a rare anatomic variation of the ulnar artery, a superficial ulnar artery. The possible embryologic events responsible for this variation are discussed. In addition, they describe the surgical considerations that should be kept in mind when this abnormality is encounte...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2007-1000120

    authors: Yuksel M,Yuksel E,Weinfeld AB,Shenaq SM

    更新日期:1999-08-01 00:00:00

  • Enhancement of fluorescein perfusion in experimental skin flaps following postischemic washout with iloprost, urokinase, verapamil, and University of Wisconsin solution.

    abstract::The enhancement of blood flow in experimental skin flaps following postischemic perfusion washout was investigated in rats. Unilateral island skin flaps based on the superficial epigastric vessels were raised and subjected to 6 hr of primary ischemia. Group 1 was designated as a control and did not undergo postischemi...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2007-1006753

    authors: Israeli D,Senderoff DM,Zhang WX,Urken ML,Weinberg H

    更新日期:1993-11-01 00:00:00

  • Free vascularized medial femoral condyle corticocancellous flap for treatment of challenging upper extremity nonunions.

    abstract:BACKGROUND:Nonunions in the upper extremity are challenging for the reconstructive surgeon. The evolution of microsurgical techniques has allowed for the reliable use of free vascularized bone flaps. METHODS:In a retrospective study, patients with challenging upper limb nonunions who underwent free vascularized cortic...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-0034-1390045

    authors: Fei W,Danmou X,Dong R,Wei F,Eberlin KR,Yan C,Wusheng K

    更新日期:2015-02-01 00:00:00

  • Epidural anesthesia during lower extremity free tissue transfer.

    abstract::A continuous epidural bupivacaine infusion was used for anesthesia in 20 patients who underwent lower extremity free tissue transfer. In 60 percent of the patients, general anesthesia supplementation with nitrous oxide was used for comfort during prolonged lying on the operating table. In all cases, this technique pro...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-2007-1006939

    authors: Strecker WB,Wood MB,Wedel DJ

    更新日期:1988-07-01 00:00:00

  • Indocyanine Green Lymphography, Lymphoscintigraphy, and Genetic Analysis in Nonsyndromic Primary Lymphedema: The Distal Dermal Backflow Grading System and the Print Sign.

    abstract:BACKGROUND: Investigating correlations between clinical, instrumental, and genetic features of primary lymphedema (PL) with the aim to facilitate the diagnosis, the staging, and the management of this subgroup of patients. METHODS: A prospective observational study was conducted from September 2016 to May 2018, includ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-0039-1698748

    authors: Mangialardi ML,Lorenzano V,Pagliara D,Visconti G,Gentileschi S,Salgarello M

    更新日期:2020-03-01 00:00:00

  • Outcomes of Muscle Reinnervation with Direct Nerve Implantation into the Native Motor Zone of the Target Muscle.

    abstract::Background Our recent work has demonstrated that the native motor zone (NMZ) within a given skeletal muscle is the best site for muscle reinnervation. This study was designed to explore the outcomes of direct nerve implantation (DNI) into the NMZ of denervated sternomastoid (SM) muscle in a rat model. Methods The righ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-0036-1592362

    authors: Sobotka S,Chen J,Nyirenda T,Mu L

    更新日期:2017-02-01 00:00:00

  • Preliminary Outcomes of Distal IMAP and SEAP Flaps for the Treatment of Unstable Keloids Subject to Recurrent Inflammation and Infections in the Lower Sternal and Upper Abdominal Areas.

    abstract:BACKGROUND:We present the clinical application of the sixth internal mammary artery perforator (IMAP) and superior epigastric artery perforator (SEAP) flaps for the treatment of defects resulting from the excision of large lower sternal and upper abdominal keloids. Perforator selection and flap design were based solely...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-0035-1556078

    authors: Wang J,Min P,Grassetti L,Lazzeri D,Zhang YX,Nicoli F,Innocenti M,Torresetti M,Levin LS,Persichetti P

    更新日期:2015-11-01 00:00:00

  • Medium- and Large-Sized Autologous Breast Reconstruction using a Fleur-de-lys Profunda Femoris Artery Perforator Flap Design: A Report Comparing Results with the Horizontal Profunda Femoris Artery Perforator Flap.

    abstract:BACKGROUND: The volume of the profunda femoris artery perforator (PAP) flap limits its indications to small- and medium-sized breast reconstructions after modified radical mastectomy for cancer. We report a modified PAP flap design, including not only a vertical extension that increases its volume but also the skin sur...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章

    doi:10.1055/s-0038-1649508

    authors: Hunsinger V,Lhuaire M,Haddad K,Wirz FS,Abedalthaqafi S,Obadia D,Derder M,Marchac A,Benjoar MD,Hivelin M,Lantieri L

    更新日期:2019-01-01 00:00:00