[Myocardial morphometric study in protein-energy malnourished adults].

Abstract:

PURPOSE:To compare cardiac muscle cells width and cardiomyocyte lipofuscin pigment presence between malnourished and non-malnourished necropsied adults. METHODS:Out of 315 necropsy protocols of adults randomly chosen, those with edema, ascitis, systemic arterial hypertension, chronic liver disease, and heart disease were excluded. Malnutrition was defined by body mass index (BMI) < 17 kg/m2. Cardiomyocytes morphometry study and lipofuscin pigment counts were performed. RESULTS:Malnourished (n = 8) and controls (n = 4), respectively, showed statistical differences in relation to BMI (14.86 +/- 1.13 vs 22.02 +/- 0.9 kg/m2), heart weight/body weight ratio (0.68 +/- 0.09 vs 0.54 +/- 0.07%), cardiomyocytes width (10.91 +/- 0.77 vs 12.90 +/- 1.82 microns) and lipofuscin pigment presence (39.1 vs 54.4%). CONCLUSION:When compared with controls, necropsied malnourished adults showed decreased myocardial fibers diameters and lower lipofuscin pigment presence. These findings might reflect altered metabolism, and would be associated with harmful clinical effects in terminally ill patients.

journal_name

Arq Bras Cardiol

authors

da Cunha DF,Pedrini CH,Sousa JC,dos Reis MA,Ramos SG,da Cunha SF,Teixeira Vde P

subject

Has Abstract

pub_date

1998-11-01 00:00:00

pages

677-80

issue

5

eissn

0066-782X

issn

1678-4170

journal_volume

71

pub_type

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