Suppression of gastrin release and gastric secretion by gastric inhibitory polypeptide (GIP) and vasoactive intestinal polypeptide (VIP).

Abstract:

:Five dogs prepared with Heidenhain pouches received infusions of saline, GIP and VIP before and after a standard meat meal. Blood samples were obtained under basal conditions and at subsequent intervals for measurement of gastrin, insulin, GIP and VIP by radioimmunoassay. GIP and VIP infusions had no effect on basal levels of gastrin. GIP and VIP (in common with secretin and glucagon) were found to suppress food-stimulated release of gastrin and gastrin-stimulated acid secretion from the Heidenhain pouch. Insulin levels were significantly elevated during GIP and VIP infusions. Food released GIP (and perhaps VIP.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Villar HV,Fender HR,Rayford PL,Bloom SR,Ramus NI,Thompson JC

doi

10.1097/00000658-197607000-00016

subject

Has Abstract

pub_date

1976-07-01 00:00:00

pages

97-102

issue

1

eissn

0003-4932

issn

1528-1140

journal_volume

184

pub_type

杂志文章
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    更新日期:1986-08-01 00:00:00

  • Irrigation versus suction alone during laparoscopic appendectomy for perforated appendicitis: a prospective randomized trial.

    abstract:BACKGROUND:The efficacy of irrigating the peritoneal cavity during appendectomy for perforated appendicitis has been debated extensively. To date, prospective comparative data are lacking. Therefore, we conducted a prospective, randomized trial comparing peritoneal irrigation to suction alone during laparoscopic append...

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    更新日期:2012-10-01 00:00:00

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    更新日期:1993-11-01 00:00:00

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    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198905000-00007

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    更新日期:1989-05-01 00:00:00

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    pub_type: 杂志文章

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    pub_type: 杂志文章,多中心研究

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    更新日期:2017-03-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1097/00000658-198705000-00003

    authors: Schwartz SI,Husser WC

    更新日期:1987-05-01 00:00:00

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    pub_type: 杂志文章

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