The role of primary surgical procedure in maintaining intestinal continuity for patients with Crohn's colitis.

Abstract:

OBJECTIVE:This study evaluates surgical procedures for Crohn's colitis. The risk of recurrence and how it interacts with future avoidance of permanent stoma and quality of life (QoL) is studied. BACKGROUND:Segmental and subtotal colectomy are widely used surgical options in isolated Crohn's colitis. It is not clear which procedure offers the best outcomes. METHODS:Patients undergoing index resection for isolated colonic Crohn's disease (CD) from 1995 to 2009, were identified from a prospectively maintained CD database. Patients were categorized into subtotal colectomy or segmental groups. Demographics, disease characteristics, operative details, morbidity, stoma formation, recurrence requiring surgery and QoL data were extracted. Recurrence and stoma free survival was calculated for each group and independent risk factors for recurrence and stoma formation identified. RESULTS:One hundred and eight patients (49 segmental, 59 subtotal) underwent primary colectomy with anastomosis. Segmental colectomy patients had significantly reduced recurrence free survival (P = 0.032) but not stoma free survival P = 0.62 on univariate analysis. On multivariate analysis, the presence of perianal sepsis (P = 0.032) and >1 medical comorbidity (P = 0.01), but not segmental colectomy, were associated with reduced SFS. There was no difference in Cleveland Global Quality of Life (P = 0.88), or Short Form Inflammatory Bowel Disease Questionnaire scores between groups (P = 0.92). CONCLUSIONS:Using a strictly defined cohort of patients, we were unable to identify segmental resection as an independent risk factor for recurrence or stoma formation and no reduction in QoL scores to suggest an adverse effect of recurrence was observed. Segmental colectomy affords good function, and our data supports the practice of a conservative approach with anastomosis in anatomically linked CD.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Kiran RP,Nisar PJ,Church JM,Fazio VW

doi

10.1097/SLA.0b013e318212b1a4

subject

Has Abstract

pub_date

2011-06-01 00:00:00

pages

1130-5

issue

6

eissn

0003-4932

issn

1528-1140

journal_volume

253

pub_type

杂志文章
  • Catecholamines: mediator of the hypermetabolic response to thermal injury.

    abstract::Hypermetabolism characterizes the metabolic response to thermal injury and the extent of energy production is positively related to the rate of urinary catecholamine excretion. Alpha and beta adrenergic blockade decreased metabolism from 69.6 +/- 5.3 Kcal/m(2)/hr to 57.4 +/- 5.2 (p < 0.01), and infusion of 6 microgm e...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197410000-00031

    authors: Wilmore DW,Long JM,Mason AD Jr,Skreen RW,Pruitt BA Jr

    更新日期:1974-10-01 00:00:00

  • Choice of abdominal operative incision in the obese patient: a study using blood gas measurements.

    abstract::Although many factors may influence the choice of the operative incision, physiologic safety in terms of the degree of postoperative hypoxemia should be considered. No data currently exist to delineate in markedly obese patients the effect of the operative incision on the extent or duration of this hypoxemia. Fifty-f...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000658-197506000-00012

    authors: Vaughan RW,Wise L

    更新日期:1975-06-01 00:00:00

  • Surgical versus medical treatment of type 2 diabetes mellitus in nonseverely obese patients: a systematic review and meta-analysis.

    abstract:OBJECTIVE:To compare surgical versus medical treatment of type 2 diabetes mellitus (T2DM) remission and comorbidities in patients with a body mass index (BMI) less than 35 kg/m2. BACKGROUND:Obesity surgery can achieve remission of T2DM and its comorbidities. Metabolic surgery has been proposed as a treatment option fo...

    journal_title:Annals of surgery

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/SLA.0000000000001014

    authors: Müller-Stich BP,Senft JD,Warschkow R,Kenngott HG,Billeter AT,Vit G,Helfert S,Diener MK,Fischer L,Büchler MW,Nawroth PP

    更新日期:2015-03-01 00:00:00

  • Preventing Parastomal Hernia Using a Modified Sugarbaker Technique With Composite Mesh During Laparoscopic Abdominoperineal Resection: A Randomized Controlled Trial.

    abstract:OBJECTIVE:The aim of this study was to assess the reduction in the incidence of parastomal hernia (PH) after placement of prophylactic synthetic mesh using a modified Sugarbaker technique when a permanent end-colostomy is needed. SUMMARY OF BACKGROUND DATA:Prevention of PH formation is crucial given the high prevalenc...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/SLA.0000000000001684

    authors: López-Cano M,Serra-Aracil X,Mora L,Sánchez-García JL,Jiménez-Gómez LM,Martí M,Vallribera F,Fraccalvieri D,Serracant A,Kreisler E,Biondo S,Espín E,Navarro-Soto S,Armengol-Carrasco M

    更新日期:2016-12-01 00:00:00

  • Hereditary spherocytosis. Recent experience and current concepts of pathophysiology.

    abstract::Hereditary spherocytosis is a clinically heterogeneous, genetically determined red blood cell membrane disorder resulting in hemolytic anemia. A deficiency of spectrin, the largest and most abundant structural protein of the erythrocyte membrane skeleton, results in the formation of spherocytes which lack the strength...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198601000-00007

    authors: Croom RD 3rd,McMillan CW,Orringer EP,Sheldon GF

    更新日期:1986-01-01 00:00:00

  • Prognostic Value of a Four-miRNA Signature in Patients with Lymph Node Positive Locoregional Esophageal Squamous Cell Carcinoma Undergoing Complete Surgical Resection.

    abstract:OBJECTIVE:This study was intended to identify prognostic biomarkers for lymph node (LN)-positive locoregional esophageal squamous cell carcinoma (ESCC) patients. SUMMARY OF BACKGROUND DATA:Surgery is a major treatment for LN-positive locoregional ESCC patients in China. However, patient outcomes are poor and heterogen...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000003369

    authors: Wen J,Wang G,Xie X,Lin G,Yang H,Luo K,Liu Q,Ling Y,Xie X,Lin P,Chen Y,Zhang H,Rong T,Fu J

    更新日期:2019-04-30 00:00:00

  • Standard versus extended lymphadenectomy associated with pancreatoduodenectomy in the surgical treatment of adenocarcinoma of the head of the pancreas: a multicenter, prospective, randomized study. Lymphadenectomy Study Group.

    abstract:OBJECTIVE:The study was conducted to determine whether the performance of an extended lymphadenectomy and retroperitoneal soft-tissue clearance in association with a pancreatoduodenal resection improves the long-term survival of patients with a potentially curable adenocarcinoma of the head of the pancreas. SUMMARY BA...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00000658-199810000-00007

    authors: Pedrazzoli S,DiCarlo V,Dionigi R,Mosca F,Pederzoli P,Pasquali C,Klöppel G,Dhaene K,Michelassi F

    更新日期:1998-10-01 00:00:00

  • Sentinel lymph node biopsy in patients with thin primary cutaneous melanoma.

    abstract:OBJECTIVES:To determine the rate and clinicopathologic factors predictive of sentinel lymph node (SLN) positivity, regional lymph node recurrence, and survival in a large series of patients with thin primary cutaneous melanoma who underwent SLN biopsy (SLNB). METHODS:Patients with thin (≤1 mm) melanomas who underwent ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3182306c72

    authors: Murali R,Haydu LE,Quinn MJ,Saw RP,Shannon K,Spillane AJ,Stretch JR,Thompson JF,Scolyer RA

    更新日期:2012-01-01 00:00:00

  • Carcinoid syndrome from gastrointestinal carcinoids without liver metastasis.

    abstract::Although patients with bronchial and ovarian carcinoid tumors can develop the carcinoid syndrome (diarrhea and/or flushing) in the absence of hepatic metastasis, it is believed that development of the carcinoid syndrome in patients with carcinoid tumors of gastrointestinal origin occurs only after the patient has hepa...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198207000-00008

    authors: Feldman JM,Jones RS

    更新日期:1982-07-01 00:00:00

  • Surgical strategies in esophageal carcinoma with emphasis on radical lymphadenectomy.

    abstract::From 1975 through 1988, 257 patients with carcinoma of the thoracic esophagus have been treated in our department. Operability was 90% (232/257); overall resectability, 77% (198/257), and for the operated group, 85% (198/232). Hospital mortality rate was 9.6% but decreased to 3% over the period 1986 to 1988. There wer...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199211000-00010

    authors: Lerut T,De Leyn P,Coosemans W,Van Raemdonck D,Scheys I,LeSaffre E

    更新日期:1992-11-01 00:00:00

  • One thousand liver transplants. The lessons learned.

    abstract:OBJECTIVE:To evaluate the first 1000 liver transplants performed at UCLA Medical Center to determine factors responsible for improved results. SUMMARY BACKGROUND DATA:Liver transplant has evolved impressively since the first case was performed in 1963. The 1980s have highlighted this progress with the development of b...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199405000-00007

    authors: Busuttil RW,Shaked A,Millis JM,Jurim O,Colquhoun SD,Shackleton CR,Nuesse BJ,Csete M,Goldstein LI,McDiarmid SV

    更新日期:1994-05-01 00:00:00

  • Evolution of the modified Rossetti fundoplication in children: surgical technique and results.

    abstract:OBJECTIVE:To compare the modified Rossetti fundoplication with the classic Nissen. SUMMARY BACKGROUND DATA:The traditional surgical treatment of gastroesophageal reflux in children has been the classic Nissen fundoplication, defined by liver mobilization, crural repair, takedown of short gastric vessels, and floppy wr...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199906000-00003

    authors: Levy MS,Sorrels CW,Wagner CW,Jackson RJ,Barnes RW,Smith SD

    更新日期:1999-06-01 00:00:00

  • Phospholipase A2 isoforms are altered in chronic pancreatitis.

    abstract:OBJECTIVE:To determine if phospholipase A2 (PLA2) type II and type IV mRNA expression and protein are altered in chronic pancreatitis. SUMMARY BACKGROUND DATA:PLA2s have an important regulatory function in several signaling pathways, especially in inflammation. In this study, we examined the expression of three PLA2 i...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199802000-00011

    authors: Kashiwagi M,Friess H,Uhl W,Graber H,Duarte R,Zimmermann A,Büchler MW

    更新日期:1998-02-01 00:00:00

  • The role of tumor necrosis factor and nitric oxide in the acute cardiovascular response to endotoxin.

    abstract:OBJECTIVE:This study was designed to examine the differential effects of tumor necrosis factor (TNF) and nitric oxide on the acute cardiovascular changes that occur in response to endotoxemia. SUMMARY BACKGROUND DATA:Recent studies have suggested that some, if not all, of the cardiovascular effects of TNF are mediated...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199601000-00009

    authors: Fahey TJ 3rd,Yoshioka T,Shires GT,Fantini GA

    更新日期:1996-01-01 00:00:00

  • Transvaginal natural orifice translumenal endoscopic surgery cholecystectomy: early evolution of the technique.

    abstract:INTRODUCTION:Initial excitement for Natural Orifice Transluminal Endoscopic Surgery (NOTES) has been partly tempered by the reality that a NOTES procedure without laparoscopic or needleoscopic-assistance has not been performed by most groups. After safely performing laparoscopically-assisted transvaginal cholecystectom...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章

    doi:10.1097/SLA.0b013e3181a802e2

    authors: Gumbs AA,Fowler D,Milone L,Evanko JC,Ude AO,Stevens P,Bessler M

    更新日期:2009-06-01 00:00:00

  • Surgical treatment of gastroesophageal reflux in infants.

    abstract::Thirty-one infants less than a year of age underwent surgery for correction of pernicious gastroesophageal reflux. Severe growth retardation from persistent vomiting was the single most important indication for surgery (25 patients). Recurrent aspiration penumonitis was another serious sequella of reflux and necessita...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197410000-00013

    authors: Randolph JG,Lilly JR,Anderson KD

    更新日期:1974-10-01 00:00:00

  • Metastatic carcinoid to the liver treated by hepatic dearterialization.

    abstract::A historical review of work bearing on the rationale for hepatic artery ligation in the treatment of malignant disease in the liver is presented, particularly the early work showing that malignant disease of the liver is supplied primarily by the arterial circulation and not by the portal. A review is presented of som...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197409000-00008

    authors: McDermott WV Jr,Hensle TW

    更新日期:1974-09-01 00:00:00

  • Primary hyperparathyroidism in the 1990s. Choice of surgical procedures for this disease.

    abstract::Many advances have occurred in recent years in the diagnosis, localization, and treatment of primary hyperparathyroidism. Several different operative choices for primary hyperparathyroidism also have been proposed--a unilateral approach versus the standard bilateral parathyroid exploration. The unilateral approach is ...

    journal_title:Annals of surgery

    pub_type: 杂志文章,评审

    doi:10.1097/00000658-199204000-00002

    authors: Kaplan EL,Yashiro T,Salti G

    更新日期:1992-04-01 00:00:00

  • The HYSLAR trial: a prospective randomized controlled trial of the use of a restrictive fluid regimen with 3% hypertonic saline versus lactated Ringers in patients undergoing pancreaticoduodenectomy.

    abstract:OBJECTIVE:This study was designed to determine whether the volume and type of fluid administered for pancreaticoduodenectomy impacts postoperative outcomes. BACKGROUND:Three percent hypertonic saline (HYS) has been suggested as a means of reducing the volume of fluid required to sustain tissue perfusion in the periope...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0000000000000872

    authors: Lavu H,Sell NM,Carter TI,Winter JM,Maguire DP,Gratch DM,Berman RA,Feil MG,Grunwald Z,Leiby BE,Pequignot EC,Rosato EL,Yeo CJ

    更新日期:2014-09-01 00:00:00

  • Lung vascular injury with protease infusion. Relationship to plasma fibronectin.

    abstract::Fibronectin exists in a soluble form in plasma and in an insoluble form in tissues. Plasma fibronectin can modulate phagocytic function as well as incorporate into the tissue matrix where it is believed to influence microvascular integrity and tissue repair. The temporal alterations in plasma and lung lymph fibronecti...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198508000-00016

    authors: Cohler LF,Saba TM,Lewis EP

    更新日期:1985-08-01 00:00:00

  • Computerized nuclear morphometry: a new morphologic assessment for advanced gastric adenocarcinoma.

    abstract:OBJECTIVE:To evaluate the correlation between the morphologic nuclear features and clinicopathologic parameters in patients with advanced gastric cancer. SUMMARY BACKGROUND DATA:Nuclear profiles have been reported as useful prognostic predictors in various cancers. Data from computerized morphometries are objective an...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199901000-00007

    authors: Ikeguchi M,Oka S,Saito H,Kondo A,Tsujitani S,Maeta M,Kaibara N

    更新日期:1999-01-01 00:00:00

  • Effect of moderate hypothermia in the treatment of canine hemorrhagic shock.

    abstract::This study evaluated a possible protective and therapeutic effect of moderate hypothermia in the treatment of severe hemorrhagic shock. A modified Wiggers shock preparation was used. Normothermic dogs (Group I, N = 6) were maintained at normal body temperature throughout hemorrhagic shock and resuscitation. In Group I...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198804000-00015

    authors: Meyer DM,Horton JW

    更新日期:1988-04-01 00:00:00

  • Fibrin sealant versus mechanical stapling for mesh fixation during endoscopic extraperitoneal inguinal hernioplasty: a randomized prospective trial.

    abstract:OBJECTIVE:To compare the clinical outcome of simultaneous bilateral endoscopic totally extraperitoneal inguinal hernioplasty (TEP) using fibrin sealant (FS) and mechanical stapling for prosthetic mesh fixation. SUMMARY BACKGROUND DATA:Similar efficacy of FS and mechanical stapling for mesh fixation has been demonstrat...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.sla.0000186440.02977.de

    authors: Lau H

    更新日期:2005-11-01 00:00:00

  • Does preoperative radiation therapy enhance the probability of local control and survival in high-risk distal rectal cancer?

    abstract::One hundred forty-eight patients were treated with preoperative radiation therapy and surgery for resectable rectal adenocarcinoma at the University of Florida between 1975 and 1986. All patients had at least 5 years' follow-up; no patient was lost to follow-up. Three treatment protocols were used over the study perio...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000658-199206000-00017

    authors: Mendenhall WM,Bland KI,Copeland EM 3rd,Summers GE,Pfaff WW,Souba WW,Million RR

    更新日期:1992-06-01 00:00:00

  • Use of Prophylactic Mesh When Creating a Colostomy Does Not Prevent Parastomal Hernia: A Randomized Controlled Trial-STOMAMESH.

    abstract:OBJECTIVE:The aim of this study was to determine whether parastomal hernia (PSH) rate can be reduced by using synthetic mesh in the sublay position when constructing permanent end colostomy. The secondary aim was to investigate possible side-effects of the mesh. BACKGROUND:Prevention of PSH is important as it often ca...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/SLA.0000000000002542

    authors: Odensten C,Strigård K,Rutegård J,Dahlberg M,Ståhle U,Gunnarsson U,Näsvall P

    更新日期:2019-03-01 00:00:00

  • Chemical debridement of burns.

    abstract::The development of effective, non-toxic (local and systemic) methods for the rapid chemical (enzymatic and non-enzymatic) debridement of third degree burns would dramatically reduce the morbidity and mortality of severely burned patients. Sepsis is still the major cause of death of patients with extensive deep burns. ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197410000-00032

    authors: Levenson SM,Kan D,Gruber C,Crowley LV,Lent R,Watford A,Seifter E

    更新日期:1974-10-01 00:00:00

  • Abdominal aortic aneurysm in high-risk patients. Outcome of selective management based on size and expansion rate.

    abstract::Low mortality rates for elective surgical treatment of abdominal aortic aneurysms justify an aggressive approach in most patients. However, in high-risk patients with small aneurysms and no symptoms, the decision to operate remains a delicate balance of risk and benefit. Our observations include 99 high-risk patients ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198409000-00003

    authors: Bernstein EF,Chan EL

    更新日期:1984-09-01 00:00:00

  • The American Association of Endocrine Surgeons Guidelines for the Definitive Surgical Management of Thyroid Disease in Adults.

    abstract:OBJECTIVE:To develop evidence-based recommendations for safe, effective, and appropriate thyroidectomy. BACKGROUND:Surgical management of thyroid disease has evolved considerably over several decades leading to variability in rendered care. Over 100,000 thyroid operations are performed annually in the US. METHODS:The...

    journal_title:Annals of surgery

    pub_type: 杂志文章,实务指引

    doi:10.1097/SLA.0000000000003580

    authors: Patel KN,Yip L,Lubitz CC,Grubbs EG,Miller BS,Shen W,Angelos P,Chen H,Doherty GM,Fahey TJ 3rd,Kebebew E,Livolsi VA,Perrier ND,Sipos JA,Sosa JA,Steward D,Tufano RP,McHenry CR,Carty SE

    更新日期:2020-03-01 00:00:00

  • Association Between Intraoperative Platelet Transfusion and Early Graft Regeneration in Living Donor Liver Transplantation.

    abstract:OBJECTIVE:To evaluate the association between anesthetic management before and after graft reperfusion and early graft regeneration in living donor liver transplantation (LDLT). BACKGROUND:Sufficient graft regeneration is essential for the success of LDLT. Diverse signals start to trigger liver regeneration immediatel...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000001526

    authors: Han S,Park HW,Song JH,Gwak MS,Lee WJ,Kim G,Lee SK,Ko JS

    更新日期:2016-12-01 00:00:00

  • Ethics of Codes and Codes of Ethics: When Is It Ethical to Provide Cardiopulmonary Resuscitation During the COVID-19 Pandemic?

    abstract:OBJECTIVE:Our study aims to provide a paradigm when it is ethical to perform cardiopulmonary resuscitation (CPR) on patients during the COVID-19 pandemic. SUMMARY BACKGROUND DATA:Hospitals around the nation are enacting systems to limit CPR in caring for COVID+ patients for a variety of legitimate reasons and based on...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000004318

    authors: Kopar PK,Brown DE,Turnbull IR

    更新日期:2020-12-01 00:00:00