Antepartum diagnosis of fetal intracranial hemorrhage due to maternal Bernard-Soulier syndrome.


BACKGROUND:Bernard-Soulier syndrome, a lack of glycoprotein IB/IX, is a rare autosomal recessive bleeding disorder characterized by platelet dysfunction. Women with Bernard-Soulier syndrome are at risk of being immunized against glycoprotein IB/IX, leading to severe isoimmune neonatal thrombocytopenia. CASE:A 26-year-old Japanese woman, gravida 1, para 0, with Bernard-Soulier syndrome presented at 35 weeks' gestation with changes in fetal heart rate patterns and ultrasonographic findings that strongly suggested fetal intracranial hemorrhage. Management was by cesarean hysterectomy and bilateral salpingo-oophorectomy at 36 weeks, but the neonate died 6 hours after birth. CONCLUSION:Maternal immunization to glycoprotein IB/IX during pregnancy can cause severe fetal thrombocytopenia and massive intracranial bleeding.


Obstet Gynecol


Fujimori K,Ohto H,Honda S,Sato A




Has Abstract


1999-11-01 00:00:00




5 Pt 2








  • Diagnosis of placental abscess in association with recurrent maternal bacteremia in a twin pregnancy.

    abstract:BACKGROUND:Placental abscess formation is rarely recognized prenatally. We present a case detected ultrasonographically that developed from a central line infection and caused recurrent maternal bacteremia. CASE:A young woman with a 21-week twin gestation presented with recurrent fevers. She had received treatment for...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Meirowitz NB,Fleischer A,Powers M,Hippolyte F

    更新日期:2006-02-01 00:00:00

  • Uterine papillary serous carcinoma.

    abstract::Reviewed are 37 patients with the diagnosis of uterine papillary serous carcinoma. Clinically, 19 patients presented as stage I, 9 as stage II, 1 as stage III, and 8 as stage IV. Four of 18 patients with clinical stage I disease who underwent surgery had pelvic metastases and five had disease spread beyond the pelvis....

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Chambers JT,Merino M,Kohorn EI,Peschel RE,Schwartz PE

    更新日期:1987-01-01 00:00:00

  • Peripheral subcutaneous vulvar stimulation in the management of severe and refractory vulvodynia.

    abstract:BACKGROUND:Vulvodynia is a complex and multifactorial clinical condition with severe pain that occurs in the absence of visible infectious, inflammatory, neoplastic, or neurological findings. CASE:A 35-year-old woman with 3 years of dysesthetic vulvodynia tried conventional and interventional medical treatment with in...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: De Andres J,Sanchis-Lopez N,Asensio-Samper JM,Fabregat-Cid G,Dolz VM

    更新日期:2013-02-01 00:00:00

  • Practice Bulletin No. 163 Summary: Screening for Fetal Aneuploidy.

    abstract::Prenatal genetic screening is designed to assess whether a patient is at increased risk of having a fetus affected by a genetic disorder. In contrast, prenatal genetic diagnostic testing is intended to determine, with as much certainty as possible, whether a specific genetic disorder or condition is present in the fet...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,实务指引



    更新日期:2016-05-01 00:00:00

  • Normal endometrial cells in Papanicolaou smears: prevalence in women with and without endometrial disease.

    abstract:OBJECTIVE:To determine whether the prevalence of normal endometrial cells in Papanicolaou smears of women with and those without endometrial carcinoma or hyperplasia differs significantly. METHODS:Papanicolaou smears of women with biopsy-proved endometrial hyperplasia or carcinoma diagnosed between 1990 and 1998 were ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Gomez-Fernandez CR,Ganjei-Azar P,Behshid K,Averette HE,Nadji M

    更新日期:2000-12-01 00:00:00

  • Clinical and laboratory evaluation of patients with primary amenorrhea.

    abstract::Sixty-two patients with primary amenorrhea were retrospectively categorized into 4 groups: 1) breast development absent and uterus present (29 patients), 2) breast development present and uterus absent (9 patients), 3) both breast development and uterus absent (2 patients), and 4) both breast development and uterus pr...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Mashchak CA,Kletzky OA,Davajan V,Mishell DR Jr

    更新日期:1981-06-01 00:00:00

  • Predictors of antibiotic prophylactic failure in post-cesarean endometritis.

    abstract::Despite the use of prophylactic antibiotics, endometritis occurs in 1-31% of patients after cesarean delivery. We sought to identify predictors of prophylactic antibiotic failure. In a retrospective review of 1800 cesarean deliveries, 766 patients had either ampicillin or cefazolin prophylaxis; 240 (31.3%) developed e...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Chang PL,Newton ER

    更新日期:1992-07-01 00:00:00

  • Hormones and sexuality: effect of estrogen and progestogen.

    abstract::This study was planned to determine the effects of estrogen and progestogen on female sexual behavior. Forty-nine women who had undergone hysterectomy and bilateral salpingo-oophorectomy took part in a double-blind placebo-controlled cross-over study. Over a 12-month period each woman received 3 months each of ethinyl...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Dennerstein L,Burrows GD,Wood C,Hyman G

    更新日期:1980-09-01 00:00:00

  • Antenatal detection of fetal A-V dissociation utilizing real-time B-mode ultrasound.

    abstract::Congenital heart block is an unusual cause of fetal bradycardia. Until recently, the diagnosis could be confirmed only by evaluation of the fetal cardiac electrical activity. Two cases are reported in which the diagnosis of atrio-ventricular (A-V) dissociation was confirmed in the antepartum period by real-time ultras...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Platt LD,Manning FA,Gray C,Guttenburg M,Turkel SB

    更新日期:1979-03-01 00:00:00

  • Verrucous carcinoma of the vulva associated with an unusual type 6 human papillomavirus.

    abstract::An unusually rapid growing vulvar verrucous carcinoma found associated with human papillomavirus type 6 is described. Both human papillomavirus structural antigens and deoxyribonucleic acid (DNA) sequences were detected in the tumor biopsy. The human papillomavirus genome was isolated and compared with the genome of h...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Rando RF,Sedlacek TV,Hunt J,Jenson AB,Kurman RJ,Lancaster WD

    更新日期:1986-03-01 00:00:00

  • Decreased plasma tryptophan in pregnancy.

    abstract:OBJECTIVE:To examine levels of serum tryptophan and its degradation product kynurenine in uncomplicated pregnancy, according to the week of pregnancy and the concentrations of neopterin. METHODS:Plasma was analyzed from 45 healthy pregnant women (15 in each trimester), 15 healthy puerperas, and 20 nonpregnant controls...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Schröcksnadel H,Baier-Bitterlich G,Dapunt O,Wachter H,Fuchs D

    更新日期:1996-07-01 00:00:00

  • Maternal hemodynamics and aortic diameter in normal and hypertensive pregnancies.

    abstract::The aortic diameters of 89 normotensive pregnant women were compared with those of nine rigorously defined preeclamptic women and 59 women who required antihypertensive therapy. Over the course of normal pregnancy, the diameter increased significantly; it was larger in preeclamptic than in normotensive women throughou...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Easterling TR,Benedetti TJ,Schmucker BC,Carlson K,Millard SP

    更新日期:1991-12-01 00:00:00

  • Outcome at 3 years of age in a population-based cohort of extremely preterm infants.

    abstract:OBJECTIVE:To assess health and neurodevelopmental outcome at 3 years of age in neonatal intensive care unit (NICU)-surviving children who were born at 26 or fewer weeks of gestation in a geographically defined region of Belgium from 1999 through 2000. METHODS:The study included a clinical examination and a standardize...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: De Groote I,Vanhaesebrouck P,Bruneel E,Dom L,Durein I,Hasaerts D,Laroche S,Oostra A,Ortibus E,Roeyers H,van Mol C,Extremely Preterm Infants in Belgium (EPIBEL) Study Group.

    更新日期:2007-10-01 00:00:00

  • Academic manpower for obstetrics and gynecology in the United States.

    abstract::All 119 medical schools in the United States provided information for a study of academic manpower conducted by the Association of Professors of Gynecology and Obstetrics (APGO). The average number of full-time faculty members per medical school is 13.2, with 2 positions vacant per school. Subspecialists are concentra...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Messer RH,Pearse WH,Fielden JG

    更新日期:1979-05-01 00:00:00

  • Effect of prolonged vaginal distention and sphincter transection on physiologic function of the external anal sphincter in an animal model.

    abstract:OBJECTIVE:To estimate the effect of prolonged vaginal distention and anal sphincter transection on contractile properties of the external anal sphincter. METHODS:Young female virgin rats were randomly assigned to four treatment groups (sham, vaginal distention, transection of anal sphincter plus repair, or combined di...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Wai CY,Miller RT,Word RA

    更新日期:2008-02-01 00:00:00

  • Development and validation of a nomogram for predicting outcome of patients with vulvar cancer.

    abstract:OBJECTIVE:To construct and validate a nomogram to predict relapse-free survival of patients treated for vulvar cancer. METHODS:Data from 244 patients treated for vulvar cancer at a single institution (Creteil, France) were used as a training set to develop and calibrate a nomogram for predicting relapse-free survival ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Rouzier R,Preti M,Haddad B,Martin M,Micheletti L,Paniel BJ

    更新日期:2006-03-01 00:00:00

  • An evaluation of the significance of positive oxytocin challenge test.

    abstract::Sixty-six of 390 patients studied at LAC/USC Women's Hospital between 1970 and 1973 had positive oxytocin challenge tests (OCT). Twenty-four percent of patients who were allowed direct monitored labor after a positive OCT showed no late deceleration and must be assumed to have had false-positive tests. Patients with p...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Freeman RK,Goebelsman UW,Nochimson D,Cetrulo C

    更新日期:1976-01-01 00:00:00

  • Outcome of twin pregnancies reduced from triplets compared with nonreduced twin gestations.

    abstract:OBJECTIVE:To compare the outcome of triplet pregnancies reduced to twins who reached 24 weeks' gestation with the outcome of twin pregnancies managed in the same perinatal department. METHODS:The study group included 43 triplet pregnancies reduced to twins who reached 24 weeks' gestation and were delivered between Jan...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Lipitz S,Uval J,Achiron R,Schiff E,Lusky A,Reichman B

    更新日期:1996-04-01 00:00:00

  • The association between persistent occiput posterior position and neonatal outcomes.

    abstract:OBJECTIVE:To examine the effect of persistent occiput posterior position on neonatal outcome. METHODS:This is a retrospective cohort study of 31,392 term, cephalic, singleton births. Women with neonates born in persistent occiput posterior position at delivery were compared to those with occiput anterior position. Wom...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Cheng YW,Shaffer BL,Caughey AB

    更新日期:2006-04-01 00:00:00

  • Opioid Prescribing Patterns, Patient Use, and Postoperative Pain After Hysterectomy for Benign Indications.

    abstract:OBJECTIVE:To quantify physician prescribing patterns and patient opioid use in the 2 weeks after hysterectomy at an academic institution and to determine whether patient factors predict postsurgical opioid use and pain recovery. METHODS:We conducted a prospective quality initiative study by recruiting all English-spea...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: As-Sanie S,Till SR,Mowers EL,Lim CS,Skinner BD,Fritsch L,Tsodikov A,Dalton VK,Clauw DJ,Brummett CM

    更新日期:2017-12-01 00:00:00

  • Umbilical coiling index in normal and complicated pregnancies.

    abstract:OBJECTIVE:To estimate the relation between undercoiling and overcoiling of the umbilical cord and adverse pregnancy outcome. METHODS:Umbilical cords and hospital records of 885 patients were studied in a cross-sectional study design. The umbilical coiling index was determined as the number of complete coils divided by...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: de Laat MW,Franx A,Bots ML,Visser GH,Nikkels PG

    更新日期:2006-05-01 00:00:00

  • Pregnancy success after hysteroscopic sterilization reversal.

    abstract:OBJECTIVE:To evaluate the effectiveness of hysteroscopic sterilization reversal by assessing pregnancy rates and identifying surgical complications. METHODS:All patients at a single center undergoing elective reversal of hysteroscopic sterilization for fertility were followed from January 2009 to May 2014. Eligible pa...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Monteith CW,Berger GS,Zerden ML

    更新日期:2014-12-01 00:00:00

  • The secretion of insulin-like growth factors I and II by explant cultures of fibroids and myometrium from women treated with a gonadotropin-releasing hormone agonist.

    abstract::The gonadotropin-releasing hormone agonist (GnRH-a) leuprolide acetate depot was used as a biologic probe to investigate the possible roles of insulin-like growth factors (IGFs) I and II in fibroid growth. The secretion of IGF-I and IGF-II by explant cultures of fibroids and myometria from women treated with a GnRH-a ...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Rein MS,Friedman AJ,Pandian MR,Heffner LJ

    更新日期:1990-09-01 00:00:00

  • Effect of intra-amniotic administration of Exosurf in preterm rabbit fetuses.

    abstract:OBJECTIVE:Currently, treatment of respiratory distress syndrome (RDS) of the preterm newborn incorporates exogenous surfactant administration. Because fetuses make breathing motions, we proposed that intra-amniotic administration of an exogenous surfactant, Exosurf, to the preterm rabbit fetus results in uptake of Exos...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Galan HL,Kuehl TJ

    更新日期:1992-10-01 00:00:00

  • Acute intermittent porphyria in pregnancy.

    abstract::A 27-year-old, previously healthy normotensive woman was admitted for hyperemesis gravidarum and treated with intravenous fluids and metoclopramide. Thereafter, a neuropsychiatric syndrome developed, with acute asymmetrical axonal motor-sensory polyneuropathy and marked anxiety, depression, irritability, and memory an...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Milo R,Neuman M,Klein C,Caspi E,Arlazoroff A

    更新日期:1989-03-01 00:00:00

  • Methotrexate treatment of unruptured ectopic pregnancy: a report of 100 cases.

    abstract::In an ongoing clinical trial, 100 patients with an unruptured ectopic pregnancy of 3.5 cm or less in greatest dimension were treated with an outpatient protocol of methotrexate and citrovorum factor chemotherapy. Methotrexate and citrovorum were given on alternating days until the hCG titer had decreased by 15% on 2 c...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Stovall TG,Ling FW,Gray LA,Carson SA,Buster JE

    更新日期:1991-05-01 00:00:00

  • The significance of fetal heart rate reactivity with a positive oxytocin challenge test.

    abstract::This study reviews 27 patients with positive OCTs who were subsequently allowed a trial of directly monitored labor. Of these, 19 patients (70%) developed FHR signs of fetal distress and 8 (30%) tolerated labor without late decelerations. These patients were evaluated for signs of fetal reactivity (acceleration of the...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Braly P,Freeman RK

    更新日期:1977-12-01 00:00:00

  • Maternal and neonatal outcomes of successful Kielland's rotational forceps delivery.

    abstract:OBJECTIVE:To estimate the rates of early neonatal and maternal complications in a consecutive series of successful Kielland's rotational forceps deliveries. METHODS:This was a retrospective cohort study of consecutive cases of successful rotational forceps deliveries performed in singleton pregnancies at 36 weeks of g...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Stock SJ,Josephs K,Farquharson S,Love C,Cooper SE,Kissack C,Akolekar R,Norman JE,Denison FC

    更新日期:2013-05-01 00:00:00

  • Comparison of Midwifery and Obstetric Care in Low-Risk Hospital Births.

    abstract:OBJECTIVE:To compare midwife and obstetrician labor practices and birth outcomes in women with low-risk pregnancies delivered in the hospital. METHODS:We conducted a retrospective cohort study of singleton births of 37 0/7-42 6/7 weeks of gestation at 11 hospitals between January 1, 2014, and December 31, 2018. Exclus...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Souter V,Nethery E,Kopas ML,Wurz H,Sitcov K,Caughey AB

    更新日期:2019-11-01 00:00:00

  • Improving care for depression in obstetrics and gynecology: a randomized controlled trial.

    abstract:OBJECTIVE:To evaluate an evidence-based collaborative depression care intervention adapted to obstetrics and gynecology clinics compared with usual care. METHODS:A two-site, randomized controlled trial included screen-positive women (Patient Health Questionnaire-9 score of at least 10) who met criteria for major depre...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Melville JL,Reed SD,Russo J,Croicu CA,Ludman E,LaRocco-Cockburn A,Katon W

    更新日期:2014-06-01 00:00:00