Abstract:
:The aim of this study was to validate a multi-trial biomarker approach for the evaluation of toxicological risk due to benzo(alpha)pyrene. Carcinus aestuarii, exposed to increasing concentrations of B(alpha)P in the water, was used as the bioindicator organism. A set of biomarkers were tested in order to: identify biological materials for biomarker and residue analysis; determine a group of sensitive techniques for the assessment of PAH contamination; investigate correlation between responses at different levels of biological organisation. The results underlined that BPMO activities in hepatopancreas and gills were a good biomarker of exposure to PAH-type compounds. B esterases activities in hemolymph and porphyrin patterns in excreta could be proposed as a non-destructive approach for evaluating chemical exposure in this species.
journal_name
Chemospherejournal_title
Chemosphereauthors
Fossi MC,Casini S,Savelli C,Corbelli C,Franchi E,Mattei N,Sanchez-Hernandez JC,Corsi I,Bamber S,Depledge MHdoi
10.1016/s0045-6535(99)00300-8subject
Has Abstractpub_date
2000-04-01 00:00:00pages
861-74issue
8eissn
0045-6535issn
1879-1298pii
S0045-6535(99)00300-8journal_volume
40pub_type
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