Methodological issues related to studies of lead mobilization during menopause.

Abstract:

:While there has been a substantial decline in lead exposure in the United States during the past two decades, mobilization of existing lead stored in bone potentially represents an important endogenous source of exposure for menopausal women. It has been hypothesized that lead may be mobilized from skeletal stores during conditions of high bone turnover, such as during menopause. However, such mobilization has not been documented in prospective studies. This discussion is focussed on some of the methodological difficulties to be anticipated in longitudinal studies of lead mobilization specific to menopause and the issues that need to be taken into account when evaluating the results of such studies. To evaluate whether lead mobilization occurs during menopause, a prospective repeated measures design is needed using X-ray fluorescence analysis of lead in bone and serial measurements of blood lead. Potential confounders and effect modifiers also need to be taken into account in the statistical analysis.

journal_name

Salud Publica Mex

journal_title

Salud publica de Mexico

authors

Berkowitz GS,Moline JM,Todd AC

doi

10.1590/s0036-36341999000800004

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

S88-92

eissn

0036-3634

issn

1606-7916

journal_volume

41 Suppl 2

pub_type

杂志文章,评审
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    doi:

    authors: Berumen J,Villegas N

    更新日期:1997-07-01 00:00:00

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    authors: Pérez-Cuevas R,Doubova SV,Flores-Hernández S,Muñoz-Hernández O

    更新日期:2012-01-01 00:00:00

  • [Local health systems: a transition of the organized social response].

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    journal_title:Salud publica de Mexico

    pub_type: 杂志文章,评审

    doi:

    authors: Gutiérrez G

    更新日期:1991-11-01 00:00:00

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    journal_title:Salud publica de Mexico

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    doi:

    authors: Pérez-Padilla JR,Regalado-Pineda J,Vázquez-García JC

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    pub_type: 杂志文章,评审

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    authors: Katz G,Lazcano-Ponce E

    更新日期:2008-01-01 00:00:00

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    pub_type: 杂志文章

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    authors: Mejía-Rodríguez F,Shamah-Levy T,Villalpando S,García-Guerra A,Méndez-Gómez Humarán I

    更新日期:2013-05-01 00:00:00

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    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: José MV,Olvera J

    更新日期:1992-05-01 00:00:00

  • Prospects for controlling cervical cancer at the turn of the century.

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    journal_title:Salud publica de Mexico

    pub_type: 杂志文章,评审

    doi:10.1590/s0036-36342003000900011

    authors: Franco EL,Duarte-Franco E,Ferenczy A

    更新日期:2003-01-01 00:00:00

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    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: García-Baltazar J,Figueroa-Perea JG

    更新日期:1992-07-01 00:00:00

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    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: López-Arellano O,Blanco-Gil J

    更新日期:1994-07-01 00:00:00

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    abstract::The Social Functioning Scale (SFS) is described, together with its rationale and development. The instrument consists of 35 items, and was administered to a sample of 320 adult patients of a health center. Social functioning is assessed in a semistructured, 30 minute interview. The patient reports the level of satisfa...

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    pub_type: 杂志文章

    doi:

    authors: Valencia M,Rojas E,González C,Ramos L,Villatoro J

    更新日期:1989-09-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Meneses-González F,Rea R,Ruíz-Matus C,Hernández-Avila M

    更新日期:1993-09-01 00:00:00

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    authors: Madrazo-Lajous A,Guerrero-Alcántara A

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    doi:

    authors: Banda-Arévalo JP,Salinas-Martínez R

    更新日期:1992-09-01 00:00:00

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    doi:10.1590/s0036-36342006000100004

    authors: Ramos-Ligonio A,Ramírez-Sánchez ME,González-Hernández JC,Rosales-Encina JL,López-Monteon A

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    doi:10.21149/11481

    authors: Félix-Arellano EE,Schilmann A,Hurtado-Díaz M,Texcalac-Sangrado JL,Riojas-Rodríguez H

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    abstract:OBJECTIVE:To determine the presence of Rickettsia typhi in Rhipicephalus sanguineus s.l. and Amblyomma mixtum in southern Mexico. MATERIALS AND METHODS:Ticks were collected in humans and domestic animals. The presence of Rickettsia was determined by PCR and sequencing. RESULTS:10/39 work vials amplified fragments of ...

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    doi:10.21149/10160

    authors: Ulloa-García A,Dzul-Rosado K,Bermúdez-Castillero SE,López-López N,Torres-Monzón JA

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  • [Poverty in Mexico. I. Methodology and evolution].

    abstract::This article is the first of two parts of a research report on the evolution and magnitude of poverty in Mexico. Herein are presented the methodologies used in both parts and the evolution of poverty. The Poverty Line methodology (PL), in its Standard Basket of Essential Satisfiers version, is succinctly explained. Tw...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Boltvinik J

    更新日期:1995-07-01 00:00:00

  • [Principal characteristics and diagnosis of the pathogenic groups of Escherichia coli].

    abstract::Escherichia coli colonizes the human intestinal tract within hours of birth and is considered a non-pathogenic member of the normal intestinal flora. However, there are six pathogenic groups that may produce diarrhea: enterotoxigenic (ETEC), enterohemorrhagic (EHEC), enteroinvasive (EIEC), enteropathogenic (EPEC), ent...

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    pub_type: 杂志文章,评审

    doi:

    authors: Rodríguez-Angeles G

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    pub_type: 杂志文章

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    authors: Garza-Montoya BG,Ramos-Tovar ME

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    doi:

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    更新日期:1998-09-01 00:00:00

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    authors: Durán-Nah JJ,Collí-Quintal J

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  • Cervical cancer and human papillomavirus: epidemiological evidence and perspectives for prevention.

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    更新日期:1993-11-01 00:00:00