Acute and chronic herpes zoster. An ancient scourge yields to timely therapy.

Abstract:

:With the US population aging steadily, herpes zoster represents a growing contributor to diminished quality of life. Dermatologic manifestations appear as immunity declines with age but rarely pose a significant threat, except in instances when ocular structures are involved. Pain is of more concern, because it usually accompanies and may even precede and persist after acute eruptions. In most young patients, pain is transient and bearable. Unfortunately, in the elderly--who are at highest risk for herpes zoster--pain is often more prolonged and more intense. In spite of a wide spectrum of interventions, palliative efforts remain rather ineffectual. At present, intervening as early as possible, ideally within 48 to 72 hours of disease onset, offers the greatest chance of minimizing neurologic sequelae. Inoculation with varicella vaccine in patients between ages 55 and 65 may prove to boost cell-mediated immunity sufficiently so that recrudescence of the varicella virus can be relegated to the annals of history.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Landow K

doi

10.3810/pgm.2000.06.1114

subject

Has Abstract

pub_date

2000-06-01 00:00:00

pages

107-8, 113-4, 117-8

issue

7

eissn

0032-5481

issn

1941-9260

journal_volume

107

pub_type

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