Abstract:
:The tick-borne encephalitis (TBE) virus gives rise to epidemic encephalitis. Mild forms usually manifest as influenza-like episodes or are clinically silent. MRI is usually normal in TBE. We describe severe TBE in a patient who presented with fever and altered mental status after a tick bite and a specific antibody response to TBE. MRI revealed pronounced signal abnormalities in the basal ganglia and thalamus, without contrast enhancement. These findings coincide well with neuropathological studies of severe nerve cell degeneration with inflammatory cell infiltrates, neuronophagia and reactive astrocytosis in the deep grey matter. We review the literature and discuss the relevant differential diagnosis.
journal_name
Neuroradiologyjournal_title
Neuroradiologyauthors
Alkadhi H,Kollias SSdoi
10.1007/s002340000396subject
Has Abstractpub_date
2000-10-01 00:00:00pages
753-5issue
10eissn
0028-3940issn
1432-1920journal_volume
42pub_type
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