Abstract:
:Candida lipolytica was recovered from the blood and the central venous catheter in a patient receiving allogeneic bone marrow transplantation. Two C. lipolytica strains from different geographical areas and the ATCC 9773 strain of C. lipolytica were used as controls. C. lipolytica was identified by standard methods. MICs indicated antifungal susceptibilities to amphotericin B, fluconazole, and itraconazole for all strains. In vitro testing and scanning electron microscopy showed that C. lipolytica was capable of producing large amounts of viscid slime material in glucose-containing solution, likely responsible for the ability of the yeast to adhere to catheter surfaces. Restriction fragment length polymorphisms revealed an identical profile for all clinical isolates, unrelated to those observed for the control strains. This finding suggested the absence of microevolutionary changes in the population of the infecting strain, despite the length of the sepsis and the potential selective pressure of amphotericin B, which had been administered to the patient for about 20 days. The genomic differences that emerged between the isolates and the control strains were indicative of a certain degree of genetic diversity between C. lipolytica isolates from different geographical areas.
journal_name
J Clin Microbioljournal_title
Journal of clinical microbiologyauthors
D'Antonio D,Romano F,Pontieri E,Fioritoni G,Caracciolo C,Bianchini S,Olioso P,Staniscia T,Sferra R,Boccia S,Vetuschi A,Federico G,Gaudio E,Carruba Gdoi
10.1128/jcm.40.4.1381-1386.2002subject
Has Abstractpub_date
2002-04-01 00:00:00pages
1381-6issue
4eissn
0095-1137issn
1098-660Xjournal_volume
40pub_type
杂志文章abstract::The peripheral blood lymphocytes from 48 heparinized blood specimens from human immunodeficiency virus (HIV) antibody-positive individuals were divided into two aliquots. One aliquot was reconstituted in one of the following five media. Medium 1 consisted of tryptose broth with 0.5% gelatin; medium 2 consisted of RPMI...
journal_title:Journal of clinical microbiology
pub_type: 杂志文章
doi:10.1128/JCM.27.1.88-90.1989
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journal_title:Journal of clinical microbiology
pub_type: 杂志文章
doi:10.1128/JCM.36.11.3342-3346.1998
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journal_title:Journal of clinical microbiology
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doi:10.1128/JCM.32.6.1464-1469.1994
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journal_title:Journal of clinical microbiology
pub_type: 杂志文章
doi:10.1128/JCM.11.4.398-401.1980
更新日期:1980-04-01 00:00:00
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journal_title:Journal of clinical microbiology
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更新日期:1997-03-01 00:00:00
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journal_title:Journal of clinical microbiology
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更新日期:1992-04-01 00:00:00
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journal_title:Journal of clinical microbiology
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doi:10.1128/JCM.28.8.1720-1724.1990
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journal_title:Journal of clinical microbiology
pub_type: 杂志文章
doi:
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abstract::This study compares the identification, typing, and phylogenetic relationships of the most prevalent clinical Nocardia species in Spain, as determined via sequence analysis of their housekeeping genes gyrB and rpoB, with the results returned by the gold standard 16S rRNA method. gyrB and rpoB analyses identified Nocar...
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journal_title:Journal of clinical microbiology
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doi:10.1128/JCM.26.2.380-381.1988
更新日期:1988-02-01 00:00:00
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journal_title:Journal of clinical microbiology
pub_type: 杂志文章,评审
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更新日期:1996-05-01 00:00:00
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journal_title:Journal of clinical microbiology
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journal_title:Journal of clinical microbiology
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更新日期:2015-08-01 00:00:00
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journal_title:Journal of clinical microbiology
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doi:10.1128/JCM.21.4.486-489.1985
更新日期:1985-04-01 00:00:00
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journal_title:Journal of clinical microbiology
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journal_title:Journal of clinical microbiology
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journal_title:Journal of clinical microbiology
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doi:10.1128/JCM.23.3.576-581.1986
更新日期:1986-03-01 00:00:00
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journal_title:Journal of clinical microbiology
pub_type: 杂志文章
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更新日期:1983-05-01 00:00:00